The active compounds are pilosine, isopilosine, epi- isopiloturine, and pilocarpine, the latter being the most important alkaloid present in Pilocarpus jaborandi extract, and used in its isolated base form in some of the present compositions. [google.com]

Flor: cor rósea/vinácea; pedicelo(s) presente(s); pétala(s) com quilha(s). Fruto: superfície(s) dos mericarpo(s) não rugoso(s); tamanho dos mericarpo(s) até 15 mm. [worldfloraonline.org]

[…] being used as sources of this alkaloid[ Although P[ microphyllus is presently the main source of pilocarpine\ P[ jaborandi\ commercially designated as Pernambuco jaborandi\ is still mentioned in pharmacopeias ð0Ł and used for extraction of the alkaloid [kundoc.com]

Little by little they were discovering new properties and discarding others that had been attributed up to the present era, in which exploit its properties as a cholinergic agent, ie, activates the parasympathetic nervous system. [mtplantas.com]

• Inflammation

  America, where native people have employed the plant as a natural remedy for epilepsy, convulsions, gonorrhoea, fever, influenza, pneumonia, gastrointestinal inflammations, kidney disease, psoriasis, neurosis, and as an agent to promote sweating. [tropical.theferns.info]

  Pleuritis, Meningitis and other inflammations of serous membranes,—it is remarkably efficient in removing exudations. Dropsy is its chief field of action, especially renal dropsy; but it is contraindicated when the heart is weak from any cause. [henriettes-herb.com]

  Cataract Discoloration; redness Eye feels hot during exertion when using eyes Inflammation; wounds; back of eye (behind retina - choroid) Pain from exertion of vision; in detailed work when using eyes; when reading aching; while reading Paralysis; of [abchomeopathy.com]

• Epilepsy

  America, where native people have employed the plant as a natural remedy for epilepsy, convulsions, gonorrhoea, fever, influenza, pneumonia, gastrointestinal inflammations, kidney disease, psoriasis, neurosis, and as an agent to promote sweating. [tropical.theferns.info]

  Traditional Uses Jaborandi is used mainly in the treatment of glaucoma, but it has also been used for epilepsy, convulsions, gonorrhea, ischuria, and as an anesthetic for mucous membranes, for fever, influenza, pneumonia, gastrointestinal inflammations [cloverleaffarmherbs.com]

• Pneumonia

  They have been used by herbalists for treating a range of complaints including bronchitis, asthma, pneumonia, diphtheria, colds and flu, laryngitis, renal insufficiency, hepatitis, diabetes, kidney diseases, oedema and fever[ ]. [tropical.theferns.info]

  By 1876, Jaborandi leaves were being employed in Europe in the treatment of many diseases including fever, stomatitis, colitis, laryngitis, bronchitis, influenza, pneumonia, and psoriasis. [rain-tree.com]

• Bronchial Spasm

  Symptoms include bradycardia, bronchial spasms, colics, possible cardiac collapse, convulsions, and a drop in blood pressure. A lethal dose is about 60 mg. of pilocarpine, corresponding to 5 to 10 g of the drug. [cloverleaffarmherbs.com]

  Reported side effects for non-lethal dosages of pilocarpine include vomiting, nausea, sweating, convulsions, increased heart rate, difficulty in breathing, and bronchial spasms. [rain-tree.com]

• Snoring

  Interestingly, a positive side effect of reported use of the pilocarpine eye solution drug was an improvement in sleep apnea and snoring in glaucoma patients using the drug. [rain-tree.com]

• Dyspnea

  Difficult (dyspnea) ≡ show all authors ... ▲ SKIN Skin Excessive perspiration from all parts of the body Persistent dryness of skin Dry eczema Semi-lateral sweats Chilliness with sweat. ≡ show all authors ... ▲ ABDOMEN Abdomen Diarrhoea, painless; during [abchomeopathy.com]

• Nausea

  Emptiness after stool Stomach; thirst; morning thirst; morning; on waking Nausea nausea; from looking; at moving object (see vertigo, dizziness) nausea; movement of eyes nausea; while reading nausea; when using the eyes Vomiting Nausea on looking at objects [abchomeopathy.com]

  Vertigo and nausea after using eyes. Head: headache. [qjure.com]

  Both jaborandi and pilocarpine may cause headaches and can irritate the stomach and cause vomiting and nausea. [rain-tree.com]

• Hypotension

  Symptoms that occur because of jaborandi powder overdose include bronchospasm, bradycardia, cardiac collapse, colic, convulsions, hypotension, and possible cardiac arrest. [amazondiscovery.com]

  […] pneumonia Properties/Actions Documented by Research: diaphoretic (promotes sweating), digestive stimulant, diuretic, sialagogue (increases saliva) Other Properties/Actions Documented by Traditional Use: anti-inflammatory, anticonvulsant, cardiac depressant, hypotensive [rain-tree.com]

• Jaundice

  It is useful in psoriasis, prurigo, deafness depending on syphilitic disease of the labyrinth, baldness, chronic catarrh, catarrhal jaundice, tonsillitis, and particularly dropsy. Probably it is most popularly known in preparations for the hair. [botanical.com]

  […] perspiration and salivation Mexico for edema, nephritis, pleurisy, rheumatism Peru promote perspiration, salivation, urination and milk flow Elsewhere for asthma, baldness, catarrh, deafness, diabetes, edema, lactation aid, glaucoma, intestinal problems, jaundice [rain-tree.com]

• Ulcer

  History Explorers to Brazil in the 16th century discovered that indigenous tribes used the plant to treat mouth ulcers, colds, and flu. [cloverleaffarmherbs.com]

  TRIBAL AND HERBAL MEDICINE USES In 1570, Gabriel Soares de Souza, a European observer, first recorded that the Guarani Indians of Brazil were using jaborandi to treat mouth ulcers. [rain-tree.com]

• Hyperhidrosis

  Jaborandi in the management of emotional palmar hyperhidrosis was studied. [ir.dut.ac.za]

• Renal Insufficiency

  They have been used by herbalists for treating a range of complaints including bronchitis, asthma, pneumonia, diphtheria, colds and flu, laryngitis, renal insufficiency, hepatitis, diabetes, kidney diseases, oedema and fever[ ]. [tropical.theferns.info]

  In Brazil jaborandi has been used by herbalists for bronchitis, asthma, pneumonia, diphtheria, colds and flu, laryngitis, renal insufficiency, hepatitis, diabetes, kidney diseases, edema and fever. [rain-tree.com]

• Irritability

  Exophthalmic goitre, with increased heart’s action and pulsation of arteries; tremors and nervousness; heat and sweating; bronchial irritation. A valuable remedy in limiting the duration of mumps. Non-Homeopathic Uses. [abchomeopathy.com]

  Irritability of the ciliary muscle. Eyes easily tire from slightest use. Heat and burning in eyes on use. Headache; smarting and pain in globe on use. Everything at a distance appears hazy; vision becomes indistinct every few moments. [homeoint.org]

  Eyes: staring; heat, burning, strain, smarting, tired, spasm, < slightest use, < reading, < electric or other artificial light; irritability ciliary muscle; vision hazy, indistinct, < distant objects, images retained long after using eyes; pupils contracted [qjure.com]

  ‘Both jaborandi and pilocarpine may cause headaches and can irritate the stomach and cause vomiting and nausea.’ 2 Any of the plants that yield jaborandi. [en.oxforddictionaries.com]

• Convulsions

  Symptoms include bradycardia, bronchial spasms, colics, possible cardiac collapse, convulsions, and a drop in blood pressure. A lethal dose is about 60 mg. of pilocarpine, corresponding to 5 to 10 g of the drug. [cloverleaffarmherbs.com]

  America, where native people have employed the plant as a natural remedy for epilepsy, convulsions, gonorrhoea, fever, influenza, pneumonia, gastrointestinal inflammations, kidney disease, psoriasis, neurosis, and as an agent to promote sweating. [tropical.theferns.info]

  Symptoms that occur because of jaborandi powder overdose include bronchospasm, bradycardia, cardiac collapse, colic, convulsions, hypotension, and possible cardiac arrest. [amazondiscovery.com]

• Headache

  ▲ HEAD Head Empty, hollow sensation Restlessness Headache Pain, headache; late morning noon eyes and vision (affecting or affected by); from straining eyes increasing gradually; and decreasing gradually in forehead; afternoon back of head (occiput); [abchomeopathy.com]

  ‘Both jaborandi and pilocarpine may cause headaches and can irritate the stomach and cause vomiting and nausea.’ 2 Any of the plants that yield jaborandi. [en.oxforddictionaries.com]

  Headache; smarting and pain in globe on use. Everything at a distance appears hazy; vision becomes indistinct every few moments. Retinal images retained long after using eyes. Irritation from electric or other artificial light. [homeoint.org]

• Seizure

  Mice deficient for the extracellular matrix glycoprotein tenascin-R structural hallmarks show physiological and increased hippocampal excitability, but no increased susceptibility to seizures in the pilocarpine model of epilepsy. [link.springer.com]

Extensive modern research has borne out the efficacy of many of these treatments. The leaves contain a number of medically active constituents, including alkaloids; an essential oil; terpenes and tannic acid[ ]. [tropical.theferns.info]

In 1876, the isolated pilocarpine alkaloid was introduced into conventional ophthalmology for the treatment of glaucoma. [rain-tree.com]

2004 2004 [Epidemiology of 118 cases of multiple sclerosis after 15 years of follow-up on the reference center of Hospital da Restauração, Recife, Pernambuco, Brazil]. [semanticscholar.org]

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition. [amazon.com]

The sweating may be prevented or checked by the subcutaneous injection of 1-100 of a grain of atropine. --from Parke, Davis & Co. Organic Materia Medica. Detroit, MI: Parke, Davis & Company; 1888., pg. 103-104. [stars.library.ucf.edu]

The effects are due to stimulation of the nerve-endings, and are prevented by atropine. The arterial muscles are not affected, and probably not the uterus. [chestofbooks.com]