Presentation
The mean patient age at presentation was 28.7 years (range 15 to 46 years); 18 were female and six male. [thejns.org]
Uncommon clinical presentations in three cases were related to increased cyst size caused by hemorrhage, sudden death, and postural syncope and loss of consciousness. [ncbi.nlm.nih.gov]
Vignette: A 34 year old female presents with headaches. Image Findings: A T2-weighted axial MR scan shows a mass in the pineal region. The mass is ovoid with smooth edges and is isodense to CSF. [radrounds.com]
In the present study, septation was observed in 18 PCs (32.14%). [wjgnet.com]
Entire Body System
- Asymptomatic
Asymptomatic cysts of the pineal gland are found frequently by radiological examination of the brain or at postmortem examination. Symptomatic cysts are rare, and may require surgical intervention. [ncbi.nlm.nih.gov]
Abstract Pineal cysts are usually asymptomatic; however, they may rarely cause symptoms such as chronic headache, paroxysmal headache with gaze paresis, postural syncope, loss of consciousness, and sudden death. [doi.org]
In contrast to patients with pineal neoplasms, pineal cysts are usually asymptomatic. They infrequently obstruct the aqueduct to cause hydrocephalus or compress the tectum to produce the neuro-ophthalmologic signs of dorsal midbrain dysfunction. [n.neurology.org]
- Fatigue
CONCLUSIONS: Pineal cysts can present with vague and unusual symptoms such as weakness, fatigue, depression, loss of appetite and weight loss that must be kept in the differential diagnosis. [n.neurology.org]
I have a pineal cyst like most of you, with a lot of the same symptoms (fatigue, vision problems, trouble sleeping, pressure headaches, problems with my short term memory, irritability). [steadyhealth.com]
We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: March 12, 2020 [patientslikeme.com]
Walking up the stairs I was easily fatigued. [pinealglandcystsurgery.com]
[…] smaller cysts (less than 5.0 mm) were usually asymptomatic, but for larger cysts (greater than 5.0 mm), symptoms could include headache, unexpected seizures, visual disturbances, memory loss, cognitive decline, muscle fasciculations, nausea, weakness, fatigue [youtube.com]
- Weakness
CONCLUSIONS: Pineal cysts can present with vague and unusual symptoms such as weakness, fatigue, depression, loss of appetite and weight loss that must be kept in the differential diagnosis. [n.neurology.org]
Customer: She said it could be just a weak muscle neuromd2012 : very good. [justanswer.com]
[…] believed that smaller cysts (less than 5.0 mm) were usually asymptomatic, but for larger cysts (greater than 5.0 mm), symptoms could include headache, unexpected seizures, visual disturbances, memory loss, cognitive decline, muscle fasciculations, nausea, weakness [youtube.com]
I was having all kinds of weird neurological symptoms last fall...strong pressure in my head, dizziness, weakness, headaches, etc. MRI showed nothing but a 6mm pineal cyst. [healthboards.com]
It is something to worry about when you have a bunch of symptoms such as blurred vision, double vision, eyes not focusing, spots in the eye that flicker, weakness in your legs, blacking out, dizziness, sick at your stomach, ringing in the ears, sezuires [change.org]
- Falling
If you know it takes you a while to fall asleep, start winding down earlier, and get into bed before you want to fall asleep. Consider setting an alarm to remind you to get ready for bed by a certain time. Avoid the snooze button. [healthline.com]
I was having all kinds of weird neurological symptoms last fall...strong pressure in my head, dizziness, weakness, headaches, etc. MRI showed nothing but a 6mm pineal cyst. [healthboards.com]
A member of Glenmoor Presbyterian Church, she was to enter her senior year at Beaver Local High School in the fall. She was a member of the volleyball team and had played basketball at one time. [steadyhealth.com]
While we are really not sure of all of its functions I will tell you that plenty of patients with larger pineal cysts, greater than 1 cm, have difficulty falling asleep. Melatonin at bedtime seems to remedy the insomnia. [pituitaryworldnews.org]
- Disability
A 43-year-old woman applied for Social Security disability benefits claiming to be disabled by a cyst in her pineal gland, a small endocrine gland in the brain that produces melatonin, which regulates sleep. [medicallawperspectives.com]
I had in all this time filed for SSD (Social Security Disability) and got turned down. [sclero.org]
Also Read: Pineal Cyst or Pineal Gland Cyst: Treatment, Recovery Period, Prognosis, Complications Pineal Cyst or Pineal Gland Cyst: Prevention, Social Security Disability, Coping [epainassist.com]
I had mne removed 15 months ago.....still have all the problems and worse the hole that he put removing it is stll yet to heal....it has been the worse 15 months of my life....and has left me disable....do to the the lack of being able to excerise and [steadyhealth.com]
Gastrointestinal
- Nausea
Pineal cysts manifest in childhood or early adulthood through clinical symptoms such as headaches, nausea, vomiting, visual disorders or disturbances of equilibrium. [www2.medizin.uni-greifswald.de]
If narrowing of the cerebral aqueduct occurs, many neurological symptoms may exist, including headaches, vertigo, nausea, muscle fasciculations, eye sensitivity, and ataxia. [youtube.com]
Nausea. Oh man, the nausea. I do have a very sensitive stomach but it would have been good to have a heads up that Dr. Shaianian actually expects extreme nausea after surgery. [annaelizmon.wordpress.com]
If narrowing of the aqueduct of sylvius occurs, many neurological symptoms may exist, including headaches, vertigo, nausea, eye sensitivity, and ataxia. [medhelp.org]
Pineal cyst apoplexy is a very rare entity with previously reported symptoms of severe frontal or occipital headache, gaze paresis and visual field defects, nausea or vomiting, syncope, ataxia, hearing loss and sudden death. [ncbi.nlm.nih.gov]
- Vomiting
Pineal cysts manifest in childhood or early adulthood through clinical symptoms such as headaches, nausea, vomiting, visual disorders or disturbances of equilibrium. [www2.medizin.uni-greifswald.de]
Pineal cyst apoplexy is a very rare entity with previously reported symptoms of severe frontal or occipital headache, gaze paresis and visual field defects, nausea or vomiting, syncope, ataxia, hearing loss and sudden death. [ncbi.nlm.nih.gov]
Presenting features in 20 symptomatic cases included: headache in 19; nausea and/or vomiting in seven; papilledema in five; visual disturbances in five (diplopia in three, “blurred vision” in two, and unilateral partial oculomotor nerve palsy in one); [thejns.org]
Presenting features in 20 symptomatic cases included: headache in 19; nausea and/or vomiting in seven; papilledema in five; visual disturbances in five (diplopia in three, 'blurred vision' in two, and unilateral partial oculomotor nerve palsy in one); [mayoclinic.pure.elsevier.com]
- Diarrhea
At her hearing before the administrative law judge (ALJ), the woman testified that her activities were severely limited by her pain and the side effects of the narcotic medications that she took for it, which included drowsiness and diarrhea. [medicallawperspectives.com]
Skin
- Sweating
Customer: I've never noticed a difference in pupil size neuromd2012 : and let your neurologist know Customer: or anything sweat related about different sides of my face Customer: but I shall look neuromd2012 : so it could be just a weak superior levator [justanswer.com]
These cysts may even contain sweat gland cells or hair follicle cells. These often appear in children. An epidermoid cyst is also called an epidermoid tumor. [healthcare.ascension.org]
I am constantly sweating uncontrollably. Sometimes I get a kind “fog” in my head that I can not seem to shake that will make me feel like I am moving/thinking in slow motion. Always tired. [braintumor.org]
Musculoskeletal
- Fracture
[…] diagnostics in women suspected pelvic endometriosis [Sodoben pristop k diagnostiki žensk s sumom na pelvično endometriozo] 2019 ► Mavčič Blaž; Saraph Vinay; Gilg Magdalena Maria; Bergovec Marko; Brecelj Janez; Leithner Andreas Risk factors for pathological fractures [ricinus2.mf.uni-lj.si]
Ears
- Tinnitus
Robb09 Member Location: Canada Tinnitus Since: 3/2015 Cause of Tinnitus: buzzing shaver/laptop fan whine/pellet gun/music/caff/wax/ eardrum red How are you doing nowadays @Matty ? Hope all is well. [tinnitustalk.com]
[…] mm) were usually asymptomatic, but for larger cysts (greater than 5.0 mm), symptoms could include headache, unexpected seizures, visual disturbances, memory loss, cognitive decline, muscle fasciculations, nausea, weakness, fatigue, light sensitivity, tinnitus [youtube.com]
An ischemic mechanism can be hypothesized when neuroimaging exams do not show signs of hemorrhage, as happened in a case of a vanishing pineal gland in a girl after acute onset of headaches, vomiting, dizziness, and tinnitus described by Patriarca et [gs.amegroups.com]
Some symptoms without correlation to the disease such as epilepsy, hemifacial edema, tinnitus, cervicalgia, and sarcoidosis, were also encountered. [surgicalneurologyint.com]
Eyes
- Blurred Vision
Since been 14 years old iv had strange symptoms since a bang to the head such as migraines, dizzy, nausea, hallucinations at night and waking up screaming, depression/anxiety, blurred vision, tingling on my head and face and well lots more like feeling [medhelp.org]
Presenting features in 20 symptomatic cases included: headache in 19; nausea and/or vomiting in seven; papilledema in five; visual disturbances in five (diplopia in three, “blurred vision” in two, and unilateral partial oculomotor nerve palsy in one); [thejns.org]
Presenting features in 20 symptomatic cases included: headache in 19; nausea and/or vomiting in seven; papilledema in five; visual disturbances in five (diplopia in three, 'blurred vision' in two, and unilateral partial oculomotor nerve palsy in one); [mayoclinic.pure.elsevier.com]
It is something to worry about when you have a bunch of symptoms such as blurred vision, double vision, eyes not focusing, spots in the eye that flicker, weakness in your legs, blacking out, dizziness, sick at your stomach, ringing in the ears, sezuires [change.org]
Occasionally a cyst may enlarge and press on surrounding structures causing symptoms such as headaches and blurred vision. If this occurs, the cyst can be removed using surgery. [healthunlocked.com]
- Photophobia
Clinic, Warangal, India Correspondence to Dr Anirudda Deshpande, dr.anirudda.deshpande{at}gmail.com Statistics from Altmetric.com radiology neurology Description A 24-year-old female patient presented with acute-onset, vertex headache associated with photophobia [casereports.bmj.com]
These types of issues include overstimulation problems, fatigue, headaches, memory problems, anxiety, depression, photophobia and many other symptoms can occur. For me, I mainly experience these problems when I am over tired or stressed out. [mypinealcyst.com]
She also had headache, photophobia, and phonophobia. Clinical and neurological examinations were unremarkable. [jcsm.aasm.org]
- Abnormal Eye Movement
Here are some other signs and symptoms to watch out for according to ACS and National Cancer Institute (NCI): seizures nausea and vomiting weakness or loss of feeling in the arms and legs stumbling or lack of coordination in walking abnormal eye movements [emedicinehealth.com]
- Visual Impairment
Symptoms in children and adults may include headaches, nausea, fatigue, visual impairments, double vision, memory problems, and seizures. In children, precocious puberty has been identified as a key indicator of a pineal tumor. [skullbaseinstitute.com]
Psychiatrical
- Fear
I quickly gripped the railing, I was accompanied by feelings of anxiety or fear. When I stepped out of the elevator everything turned back to normal and all the problems were gone. [pinealglandcystsurgery.com]
I it's not the constant health panic, it's the fear that I'm going crazy or schizophrenic. I can't even try any SSRIs because I'll take one and go straight into panic. I got prescribe Paxil and boom.. [nomorepanic.co.uk]
I've experienced the full range of emotions, anger, scared, fear of death, sadness, resolve, determination, etc, just depends on the moment and time and day. [inspire.com]
I have eaten very little in 3 days for fear of the pain with the cramps. Any idea on what I should do, or suggestions would be appreciated. XXXXXXX MD Brief Answer: Cramps under right ribs/ Under Evaluation Detailed Answer: Hi Dear !! [healthcaremagic.com]
- Anxiety Disorder
Alcohol Induced Neuropathy... by Icehouse 05-12-2019 02:37 PM 144 3,216 Anxiety and OCD (4 Viewing) A support forum for all anxiety disorders, including obsessive-compulsive disorder (OCD). [neurotalk.psychcentral.com]
Neurologic
- Headache
Abstract Pineal cysts are usually asymptomatic; however, they may rarely cause symptoms such as chronic headache, paroxysmal headache with gaze paresis, postural syncope, loss of consciousness, and sudden death. [doi.org]
Abstract The cyclic nature of some of headache disorders is closely related to melatonin, which is secreted by the pineal gland. We report a 29-year-old male patient with a 2.5-year history of headaches that woke him in the middle of the night. [ncbi.nlm.nih.gov]
Usually, they are asymptomatic; however, clinical signs such as headache, sight disorders, dizziness or hydrocephalia may occur. [termedia.pl]
One year post-operatively the patient is totally free of symptoms, headache and double vision. [www2.medizin.uni-greifswald.de]
Since your headaches might not be due to the pineal gland cyst, discuss with your doctor other possible causes for your headaches. A variety of primary headache and medical conditions can lead to chronic headaches. [newsnetwork.mayoclinic.org]
- Seizure
(these seizures have started recently) and more. [gofundme.com]
Although most pineal cysts are small, large pineal cysts can cause a variety of symptoms such as: headaches, normal pressure hydrocephalus (increased pressure on the brain due to build-up excess fluid), and even seizures and loss of consciousness in extreme [med.uth.edu]
We report a new complication of intracystic hemorrhage in a large pineal gland cyst in a 40-year-old man with new onset seizures. [ncbi.nlm.nih.gov]
Not to mention, after the three seizures I have had I am extremely hesitant in driving a motor vehicle. I day dream all the time about the possibilities. [braintumor.org]
This especially struck home when I read the fact that "large symptomatic pineal cysts may potentially cause serious conditions such as seizures and loss of consciousness", as our son has most recently been exhibiting "seizure-like episodes" and "vision [ourabrammayhem.weebly.com]
- Ataxia
Pineal cyst apoplexy is a very rare entity with previously reported symptoms of severe frontal or occipital headache, gaze paresis and visual field defects, nausea or vomiting, syncope, ataxia, hearing loss and sudden death. [ncbi.nlm.nih.gov]
[…] all 24 cases (range 3 months to 10 years) revealed no complications in 21, mild ocular movement deficit in one, gradually resolving Parinaud's syndrome in one, and radiographic evidence of a postoperative venous infarct of the superior cerebellum with ataxia [thejns.org]
If narrowing of the cerebral aqueduct occurs, many neurological symptoms may exist, including headaches, vertigo, nausea, muscle fasciculations, eye sensitivity, and ataxia. [youtube.com]
Symptoms include: • headache • nausea • papilledema • diplopia • vertical gaze paralysis • seizure • ataxia • hemiparesis Radiolographic findings: On CT: • sharply defined wall • hypodense to CSF • calcification in cyst wall in half of cases • if present [radrounds.com]
- Insomnia
Try a natural sleep aid WEBSITES: causes cures & treatment www.helpguide.org/life/insomnia 17 proven tips for insomnia Insomnia & sleep National sleep foundation www. Insomnia (chronic and acute)causes www.webmd.com/sleep... [mdjunction.com]
Here, the authors report an unusual case of a 28-year-old male patient with pineal cyst apoplexy, presenting with headache, insomnia, and sexual dysfunction symptoms who is being managed conservatively and observed for two years by an academic tertiary [ncbi.nlm.nih.gov]
Recently I began suffering bad insomnia. Could the cyst be hindering melatonin? My neurologists say no and think insomnia due to stress. [healthcaremagic.com]
[…] online forums include: severe fatigue, dizziness, memory loss, excruicating headaches and eye pain, migranes, worsening depression, mood swings, neck pain, jaw pain, numbness on side of face, brain fog, blurred vision, worsening eyesight, eye floaters, insomnia [medhelp.org]
- Tremor
I’ve ever dealt with in my life. main symptoms and constant : nausea/vertigo, loss of vision, blurred vision and speech, extreme fatigue or insomnia some nights, vomiting, light sensitivity, memory loss, migraines, bilateral ear pain, muscle spasms, tremors [gofundme.com]
Additional symptoms include memory problems, lack of coordination and tremor. Diagnosis Scans A magnetic resonance imaging (MRI) of the brain is the most important imaging study. It will show the location, size, and shape of the tumor. [uclahealth.org]
[…] nausea and vomiting visual problems light sensitivity lack of muscle coordination lethargy vertigo sleep problems coma In addition to the above, there are also some core anecdotal symptoms derived from forums with people with pineal gland cysts: fatigue tremors [hubpages.com]
He also said the tremors I was having in my arms and head was just my body's reaction to pain. I guess this is true since I only have them when the pain's severe. [healthboards.com]
Workup
Measurement of AFP and b-hCG in serum and CSF is routine in the preoperative workup. [aboutcancer.com]
Therefore, a rigorous and uniform preoperative workup is a requisite for all patients thought to harbor a pineal region tumor. Any endocrine abnormalities should be investigated prior to surgery. [emedicine.medscape.com]
Treatment
SRS is increasingly being used to treat pineal region tumors, either as an additional therapy after conventional treatments or as a primary treatment. [wikidoc.org]
No controlled trials of treatment interventions were identified; evidence on treatment is mainly found in case reports. No evidence-based guidelines for the diagnosis and treatment of pineal gland cysts were identified. [crd.york.ac.uk]
Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. [practo.com]
The patient underwent oral melatonin treatment (6 mg/day). After 1 month he experienced a 70% reduction in his symptoms. [ncbi.nlm.nih.gov]
Prognosis
Extragonadal GCTs (including pineal region) have a poorer prognosis than gonadal GCTs. [aboutcancer.com]
Prognosis The response of tumours to various treatment modalities depends on the tumour subtype. [ 3 ] Generally, intracranial germinomas have an excellent prognosis on account of their sensitivity to radiotherapy (the five-year overall survival rate [patient.info]
It is quite difficult for me to recount the exact timing of my prognosis, but, with the help of my boyfriend documenting for me, we could recall that my first seizure had occurred around February of last year. [braintumor.org]
[…] postcontrast imaging is delayed (60-90 min), gadolinium may diffuse into the cyst fluid and may lead to the mass appearing solid in atypical cases enhancement may be nodular, or there may be evidence of previous hemorrhage into the cysts Treatment and prognosis [radiopaedia.org]
Etiology
The underlying etiological association is unclear and this case exemplifies the enigmatic role of the pineal gland in puberty. Contributors : KVS, AV worked up the patient clinically. [indianpediatrics.net]
The etiology of pineal cysts is still under debate; however, several postulates have been presented in an attempt to explain their origin. [thejns.org]
Epidemiology
Objective Epidemiological and clinical evaluation of the occurrence of pineal cysts in children treated in a single oncological ward over a period of 7 years. [termedia.pl]
Epidemiology, pathophysiology, and surgical approaches. 9:239–266 Google Scholar 15. Sano K, Matsutani M (1981) Pineal (germinoma) treated by direct surgery and postoperative irradiation. Child's Brain 8:81–97 Google Scholar 16. [link.springer.com]
diagnostic dilemmas] 2005 ► Hicheri J; Badri T; Fazaa B; Zermani R; Kourda N; Ben-Jilani S; Kamoun MR Scrotal calcinosis: pathogenesis and case report 2005 ► Šoba Barbara; Logar Jernej Molekularna epidemiologija humane kriptosporidioze [Molecular epidemiology [ricinus2.mf.uni-lj.si]
Epidemiology [ 3 ] They account for 0.4-1% of adult intracranial tumours. They make up 3-8% of childhood intracranial tumours, with most occurring between the first and second decade of life. [patient.info]
Currently, initial surgical management for tissue diagnosis, and possible resection, is the standard of care for most children with pineal region tumors. [16] Epidemiology Pineal region tumors make up 0.4-1.0% of intracranial tumors in adults and 3-8% [emedicine.medscape.com]
Pathophysiology
It also provides further support that the pineal region may play a role in the pathophysiology of psychiatric diseases, although more studies will be needed to elucidate this interesting connection. [mdanderson.elsevierpure.com]
Epidemiology, pathophysiology, and surgical approaches. 9:239–266 Google Scholar 15. Sano K, Matsutani M (1981) Pineal (germinoma) treated by direct surgery and postoperative irradiation. Child's Brain 8:81–97 Google Scholar 16. [link.springer.com]
Pathophysiology Tumors and Cysts Due to the pineal gland's location, any tumor or cyst formation would lead to the compression of the aqueduct of Sylvius. It is the aqueduct of Sylvius that allows the cerebrospinal fluid (CSF) to circulate out. [statpearls.com]
We review present an up-to-date review including the anatomy, embryology, and physiology of the pineal gland and its ability to secrete hormones including melatonin, pathophysiology of pineal gland tumors, cysts, and calcifications, their clinical presentation [read.qxmd.com]
The pathophysiology of pineal region tumors is mostly a result of anatomic compression of adjacent structures, although local infiltration of neural structures can lead to symptoms in cases of highly invasive tumors. [emedicine.medscape.com]
Prevention
The wedge that you must sleep on 3 weeks after surgery to prevent brain bleeding. [annaelizmon.wordpress.com]
I have also been put on tablets to prevent my absent seizures I am now experiencing daily! [gofundme.com]
Centers for Disease Control and Prevention says. Certain brain cysts, such as arachnoid cysts, can form later in life from causes other than developmental abnormalities. [livestrong.com]
Also Read: Pineal Cyst or Pineal Gland Cyst: Treatment, Recovery Period, Prognosis, Complications Pineal Cyst or Pineal Gland Cyst: Prevention, Social Security Disability, Coping [epainassist.com]
Parinaud syndrome prevents a person from moving his or her eyes up and down. The thalamus can be affected, and if so, there can be disturbances on that side of the body which would result in weakness and loss of sensation. [statpearls.com]