We present the first report on familial pineocytoma. The propositus, a 31-year-old man, presented with incontinence due to a cystic and haemorrhagic tumour of the pineal region. [ncbi.nlm.nih.gov]

CASE DESCRIPTION: We present a case of a 28-year-old man with a 35-mm tumor of the pineal region. Considering the typical radiological and pathologic presentation, the tumor was first diagnosed as pineocytoma. [read.qxmd.com]

We evaluated the occurrence of subjective ... 28 Gempt Jens - - 2012 We present the first report on familial pineocytoma. The propositus, a 31-year-old man, presented with incontinence due to a cystic and haemorrhagic tumour of the pineal region. [biomedsearch.com]

• Weight Gain

  The tumor's effect on the hypothalamus will lead to weight gain, disruption of sleep, disruption of temperature control, and water regulation. Cerebellar involvement would result in motor impairment. [wikidoc.org]

• Myopathy

  […] in maloriented specimens. b) Pineal parenchymal tumors: Pineoblastoma, Pineocytoma (c) Embryonal Tumors: Medulloblastoma Possible differential diagnosis of DEP include blow-out fracture of the orbital floor, congenital or acquired fibrosis, endocrine myopathy [medical-dictionary.thefreedictionary.com]

• Suggestibility

  This case suggests that distant, subarachnoidal metastasis to the spinal cord can occur in pineocytomas even after long-term dormancy. [ncbi.nlm.nih.gov]

• Incontinence

  The propositus, a 31-year-old man, presented with incontinence due to a cystic and haemorrhagic tumour of the pineal region. His 34-year-old sister, who had suffered from tinnitus for several years, also had a pineal tumour. [ncbi.nlm.nih.gov]

  […] parenchymal tumors, manifesting with symptoms such as Parinaud's syndrome (a group of eye movement abnormalities and pupil dysfunction, including deficiency in upward-gaze and convergence-retraction nystagmus), headaches, balance impairment, urinary incontinence [orpha.net]

  Nausea Fatigue Blurred vision / double vision Memory problems Urinary incontinence Balance problems / dizziness Hydrocephalus (the abnormal enlargement of the brain ventricles due to a build up of cerebrospinal fluid (CSF) Paralysis in upward gaze ( Parinaud [arthriticchick.com]

• Communicating Hydrocephalus

  It has mass effect on the adjacent structures with stenosis of the cerebral aqueduct (some flow still present on cine imaging) and associated non-communicating hydrocephalus affecting the lateral ventricles and 3rd ventricle. [radiopaedia.org]

  From September 2007 to February 2012, 43 patients were treated in Chinese People's Liberation Army General Hospital, including 30 male and 14 female patients, with pineal region tumors and non-communicating hydrocephalus were enrolled, who ... 4 Jouvet [biomedsearch.com]

• Sciatica

  Recurrence In February 2009, the patient returned to clinic complaining of bilateral resting tremors and left hand numbness over the previous year, progressive low back pain and sciatica-like pain running down her left leg into her left foot for the past [pagepress.org]

• Convergence Nystagmus

  Parinaud’s syndrome includes upward gaze palsy with impaired convergence, nystagmus retractorius, eyelid retraction ( Collier’s sign ), and light-near dissociation (pseudo Argyll-Robertson pupil), where pupils are dilated and respond poorly to light but [ispn.guide]

• Dysarthria

  On neurologic examination, he had apraxia of eyelid opening, vertical supranuclear gaze palsy, dysarthria, and dysphagia. There was facial hypomimia, moderate axial rigidity, symmetrical bradykinesia, and no tremor. [neurology.org]

• Bradykinesia

  There was facial hypomimia, moderate axial rigidity, symmetrical bradykinesia, and no tremor. Gait was characterized by freezing and postural instability. Cognitive assessment was normal. [neurology.org]

No other workup or CSF markers were obtained. MRI of 10/05: Lesion is recorded as 8×10 mm. [med.virginia.edu]

Therefore, a rigorous and uniform preoperative workup is a requisite for all patients thought to harbor a pineal region tumor. Any endocrine abnormalities should be investigated prior to surgery. [emedicine.medscape.com]

Therefore differences in workup, diagnosis and treatment modalities are unavoidable and comparison of the data of a long time period is difficult. PPT are not a homogeneous histological tumor entity. [ro-journal.biomedcentral.com]

Abstract Given its rarity, appropriate treatment for pineocytoma remains variable. [ncbi.nlm.nih.gov]

At the time of treatment planning, the target volume was 1.68 cc and measured approximately 13×15×20 mm. Daily treatment was delivered by a dedicated 6-MV linear accelerator with micromultileaf collimators (Novalis, Heimstetten, Germany). [pagepress.org]

Some patients will undergo other treatments such as radiation treatments for residual tumor or chemotherapy, particular in more malignant tumors. [nervous-system-diseases.com]

SRS is increasingly being used to treat pineal region tumors, either as an additional therapy after conventional treatments or as a primary treatment. [wikidoc.org]

Pineocytomas are pineal parenchymal tumour, are generally non-agressive and have a relatively good prognosis. [operativeneurosurgery.com]

Pineocytomas are a relatively benign pineal parenchymal tumor that have a relatively good prognosis. [radiopaedia.org]

Acta Path Microbiol Immunol Scand Sect A 95: 113-11 Numoto RT (1994) Pineal parenchymal tumors: cell differentiation and prognosis. [path.upmc.edu]

The most-common etiologies are pineal gland tumors and midbrain infarction. Pineal gland tumors are rare tumors that show a predilection for males. [ncbi.nlm.nih.gov]

There was no evidence of infection, with negligible leukocytes and negative tests for syphilis, cryptococcus, tuberculosis and other infectious etiologies. In March 2009, a left frontal craniotomy and dural biopsy were performed. [pagepress.org]

The mechanisms behind HPG activation are complex and a clear etiology for early activation is often not elucidated. [biomedsearch.com]

This publication takes advantage of the knowledge and experience of Japanese experts in pineal tumors, with emphasis on epidemiology and pathological diagnosis. [books.google.com]

Epidemiology Pineocytoma accounts for less than 1% of all intracranial tumors, but about 45% of all pineal parenchymal tumors. These lesions usually arise in adults between the ages of 25-35. Both sexes are affected equally. [prod.wiki.cns.org]

Epidemiology Pineocytomas can be encountered at any age but mostly occur in young adults in the second decade of life Unlike pineal germinomas both genders are equally affected. [operativeneurosurgery.com]

Accessed on November 20, 2015 ↑ 12.0 12.1 Epidemiology of pineocytoma. Dr Bruno Di Muzio and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pineocytoma. [wikidoc.org]

[…] intermediate differentiation (grade II or III) Papillary tumor of the pineal region (grade II or III) Pineoblastoma (grade IV) According to the WHO classification of tumors of the central nervous system, pineocytoma is classified into a WHO grade I tumor. [2] Pathophysiology [wikidoc.org]

The pathophysiology of pineal region tumors is mostly a result of anatomic compression of adjacent structures, although local infiltration of neural structures can lead to symptoms in cases of highly invasive tumors. [emedicine.medscape.com]

MedMaven Editor Mar 21 Neuropathy (Numbness and Tingling )- How is it Prevented and Treated? Chemotherapy damage to nerves can cause numbness, tingling, & a loss of sensation known as peripheral neuropathy. [news.cancerconnect.com]

This consequently prevents us from addressing the potential for systematic flaws or differences among studies in a statistically meaningful way. [link.springer.com]

Parinaud syndrome prevents a person from moving his or her eyes up and down. The thalamus can be affected, and if so, there can be disturbances on that side of the body which would result in weakness and loss of sensation. [wikidoc.org]

A standardized protocol for the prevention of clinically relevant venous air embolism during neurosurgical interventions in the semisitting position. Neurosurgery. 2009. 64: 533-8 13. Jakola AS, Bartek J, Mathiesen T. [surgicalneurologyint.com]