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Pituicytoma


Presentation

  • […] signs, and biopsy.We present a case of pituicytoma with corticotroph hyperplasia in a 46-year-old woman with typical Cushing syndrome.[ncbi.nlm.nih.gov]
  • We present a report of two patients with pituicytomas and review the literature regarding treatment and prognosis for this unusual lesion. Possible histogenetic relationships of this tumor with other pituitary neoplasms are presented.[ncbi.nlm.nih.gov]
  • A 42-year-old woman presented with a history of amenorrhea and vertigo, and a 62-year-old woman presented with mild headache. Both patients had mild hyperprolactinemia and one had mild anterior pituitary dysfunction.[ncbi.nlm.nih.gov]
  • Previously reported pituicytomas all presented with signs and symptoms relating to mass effect or endocrinological dysfunction.[ncbi.nlm.nih.gov]
  • A summary of the clinical and pathologic features of this case, as well as the 12 previously reported cases, is presented.[ncbi.nlm.nih.gov]
Hyperthermia
  • After surgery, in addition to endocrine disorders, the patient presented severe neurological sequelae and hyperthermia, likely due to damage of the hypothalamus, followed by a progressive metabolic syndrome.[ncbi.nlm.nih.gov]
Spontaneous Hemorrhage
  • Benveniste RJ, Purohit D, Byun H (2006) Pituicytoma presenting with spontaneous hemorrhage. Pituitary 9:53–58 PubMed CrossRef Google Scholar 3. Brandao RA, Braga MH, de Souza AA, Reis BL, Faraj de Lima FB (2010) Pituicytoma.[doi.org]
  • Benveniste RJ, Purohit D, Byun H (2006) Pituicytoma presenting with spontaneous hemorrhage. Pituitary 9:53–58 CrossRef PubMed Google Scholar 43. Nakasu Y, Nakasu S, Saito A, Horiguchi S, Kameya T (2006) Pituicytoma. Two case reports.[doi.org]
Overeating
  • There has been no regrowth of the residual tumor, as shown on magnetic resonance imaging, over a follow-up period of 1.5 years. The final pathological diagnosis was pituicytoma.[ncbi.nlm.nih.gov]
  • No recurrence was found over 8 years of follow-up.Pituicytoma is a rare type of sellar tumor. Pituicytomas in patients with Cushing syndrome are rarer still.[ncbi.nlm.nih.gov]
  • We report two patients with pituicytoma operated on at our Institute over 8 years. Imaging of one patient showed a parasellar and medial temporal extension, which has not been reported to our knowledge.[ncbi.nlm.nih.gov]
  • We report the case of a 62-year-old man with a recurrent sellar mass over a 21-year-period. The patient initially presented in 1990 with jaundice and tested positive for hepatitis B.[academic.oup.com]
  • […] multicenter study , reporting the clinical manifestations, radiological characteristics, histopathological features, treatment strategies and long-term outcome s of patients who have been treated for a Pituicytoma at various institutions in Paris, France over[operativeneurosurgery.com]
Scotoma
  • We report a case of vision loss and a junctional scotoma in a 43-year-old woman caused by compression of the optic chiasm by a pituitary tumor.[karger.com]
  • Pituicytoma: a case report with literature revisited. ( 24056664 ) Shenoy AS...Mehta JK 2013 27 Pituicytoma of the neurohypophysis: analysis of cell proliferation biomarkers. ( 23041408 ) Karamchandani J....Kovacs K. 2012 28 Decreased vision and junctional scotoma[malacards.org]
  • : a case report with literature revisited. ( 24056664 ) Shenoy A.S....Mehta J.K. 2013 27 Pituicytoma of the neurohypophysis: analysis of cell proliferation biomarkers. ( 23041408 ) Karamchandani J....Kovacs K. 2012 28 Decreased vision and junctional scotoma[malacards.org]
  • Huynh N, Stemmer-Rachamimov AO, Swearingen B, Cestari DM (2012) Decreased vision and junctional scotoma from pituicytoma: case report. Ophthalmol 3:190–196 Google Scholar 36.[doi.org]
Cutis Laxa
  • HGA is an autosomal-dominant systemic amyloidosis, characterized by slowly progressive neurological deterioration with corneal lattice dystrophy, cranial neuropathy, and cutis laxa.[ncbi.nlm.nih.gov]
Cranial Neuropathy
  • HGA is an autosomal-dominant systemic amyloidosis, characterized by slowly progressive neurological deterioration with corneal lattice dystrophy, cranial neuropathy, and cutis laxa.[ncbi.nlm.nih.gov]

Workup

  • During the course of his workup, an MRI of the brain was performed, which showed a pituitary/sellar mass. In 1997, the patient had a recurrence of the tumor and underwent surgery, which suggested the diagnosis of pituicytoma.[academic.oup.com]

Treatment

  • Tumor resection is the primary treatment option, but remains subtotal due to excessive bleeding in many cases. The search for alternative or additional treatment regimens is necessary.[ncbi.nlm.nih.gov]
  • Surgical removal is the treatment of choice for this neoplasm. In recent years the endoscopic endonasal approach has proven to be a viable and effective alternative to standard craniotomy.[ncbi.nlm.nih.gov]
  • Currently, the optimal treatment is gross total resection, and confirmed diagnosis relies upon pathological tests. Regular MRI follow-up is recommended.[ncbi.nlm.nih.gov]
  • To round out the clinician's understanding of the illness, a patient describes the experience of diagnosis, treatment, and follow-up.[books.google.com]
  • Awareness of this entity is essential for planning management and treatment.[ncbi.nlm.nih.gov]

Prognosis

  • The prognosis and role of adjuvant therapy remain unclear for this discrete noninfiltrative glioma.[ncbi.nlm.nih.gov]
  • With total resection, the pituicytoma appears to have a good prognosis. However, its highly vascular nature makes total resection difficult and local recurrence after subtotal resection is not uncommon.[ncbi.nlm.nih.gov]
  • We present a report of two patients with pituicytomas and review the literature regarding treatment and prognosis for this unusual lesion. Possible histogenetic relationships of this tumor with other pituitary neoplasms are presented.[ncbi.nlm.nih.gov]
  • This fourteenth volume of the series provides comprehensive, current information on the diagnosis, therapy and prognosis of brain tumors and spinal tumors.[books.google.com]
  • Volume 11: Imaging, Glioma and Glioblastoma, Stereotactic Radiotherapy, Spinal Cord Tumors, Meningioma, and Schwannomas concentrates on the diagnosis, prognosis and therapy of four types of tumors, namely Glioblastoma, Meningioma, Schwannoma and Spinal[books.google.com]

Etiology

  • Although three cases of pituicytoma with elevated plasma adrenocorticotropic hormone (ACTH) have been reported previously, the etiological mechanisms remain unknown.[file.scirp.org]

Epidemiology

  • Epidemiology PTs had a higher prevalence in the fifth and sixth decades of life, with a slight male predominance. 6) .[operativeneurosurgery.com]
Sex distribution
Age distribution

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