We present a report of two patients with pituicytomas and review the literature regarding treatment and prognosis for this unusual lesion. Possible histogenetic relationships of this tumor with other pituitary neoplasms are presented. [ncbi.nlm.nih.gov]

• Spontaneous Hemorrhage

  Benveniste RJ, Purohit D, Byun H (2006) Pituicytoma presenting with spontaneous hemorrhage. Pituitary 9:53–58 PubMed CrossRef Google Scholar 15. Chen KT (2005) Crush cytology of pituicytoma. [link.springer.com]

  Benveniste RJ, Purohit D, Byun H (2006) Pituicytoma presenting with spontaneous hemorrhage. Pituitary 9:53–58 PubMed CrossRef Google Scholar 3. Brandao RA, Braga MH, de Souza AA, Reis BL, Faraj de Lima FB (2010) Pituicytoma. [doi.org]

  Pituicytoma presenting with spontaneous hemorrhage. Pituitary 2006; 9 :53–8 [ PubMed ] [ Google Scholar ] 6. Wolfe SQ, Bruce J, Morcos JJ. Pituicytoma: Case report. Neurosurgery 2008; 63 :173–4 [ PubMed ] [ Google Scholar ] 7. [ncbi.nlm.nih.gov]

  Pituicytoma presenting with spontaneous hemorrhage. Pituitary. 2006. 9: 53-8 2. Brat DJ, Scheithauer BW, Staugaitis SM, Holtzman RN, Morgello S, Burer PC. Pituicytoma: A distinctive low-grade glioma of the neurohypophysis. [surgicalneurologyint.com]

• Amyloidosis

  HGA is an autosomal-dominant systemic amyloidosis, characterized by slowly progressive neurological deterioration with corneal lattice dystrophy, cranial neuropathy, and cutis laxa. [ncbi.nlm.nih.gov]

• Chronic Fatigue Syndrome

  "HPA axis" is now becoming a "pop" diagnosis, in a class with chronic fatigue syndrome, fibromyalgia, and multiple chemical sensitivities (except for the last, I think there is something real, but there are plenty of somatizers and it is hard to sort [pathguy.com]

• Overeating

  We report two patients with pituicytoma operated on at our Institute over 8 years. Imaging of one patient showed a parasellar and medial temporal extension, which has not been reported to our knowledge. [ncbi.nlm.nih.gov]

  Pituicytomas are typically slow growing lesions that gradually grow in size over a period of years. [elynsgroup.com]

  We report the case of a 62-year-old man with a recurrent sellar mass over a 21-year-period. The patient initially presented in 1990 with jaundice and tested positive for hepatitis B. [academic.oup.com]

• Increased Appetite

  have increased appetite), show a female pattern of fat distribution, and have delayed (if ever) appearance of primary or secondary sex characteristics. [pathguy.com]

• Cutis Laxa

  HGA is an autosomal-dominant systemic amyloidosis, characterized by slowly progressive neurological deterioration with corneal lattice dystrophy, cranial neuropathy, and cutis laxa. [ncbi.nlm.nih.gov]

• Suggestibility

  These features intermediate between a pituicytoma and a pituitary adenoma suggest that "pituicytomas" may also arise from the specialized stromal folliculo-stellate cells of the adenohypophysis, which are able to differentiate into endocrine cells. [ncbi.nlm.nih.gov]

  These features intermediate between a pituicytoma and a pituitary adenoma suggest that pituicytomas may also arise from the specialized stromal folliculo-stellate cells of the adenohypophysis, which are able to differentiate into endocrine cells. [doi.org]

• Cranial Neuropathy

  HGA is an autosomal-dominant systemic amyloidosis, characterized by slowly progressive neurological deterioration with corneal lattice dystrophy, cranial neuropathy, and cutis laxa. [ncbi.nlm.nih.gov]

• Polyneuropathy

  Two known gene point mutations result in gelsolin amyloid deposition, a characteristic feature of a rare type of familial amyloid polyneuropathy (FAP), the Finnish-type FAP, or hereditary gelsolin amyloidosis (HGA). [ncbi.nlm.nih.gov]

During the course of his workup, an MRI of the brain was performed, which showed a pituitary/sellar mass. In 1997, the patient had a recurrence of the tumor and underwent surgery, which suggested the diagnosis of pituicytoma. [academic.oup.com]

The lab workup of acromegaly is straightforward. Your screening test is a spot blood insulin-like growth factor I (IGF-I). If this is normal, acromegaly is unlikely. [pathguy.com]

Tumor resection is the primary treatment option, but remains subtotal due to excessive bleeding in many cases. The search for alternative or additional treatment regimens is necessary. [ncbi.nlm.nih.gov]

Treatment Review Less than 50 cases have been reported in the world literature till 2013 13). [operativeneurosurgery.com]

The prognosis and role of adjuvant therapy remain unclear for this discrete noninfiltrative glioma. [ncbi.nlm.nih.gov]

This fourteenth volume of the series provides comprehensive, current information on the diagnosis, therapy and prognosis of brain tumors and spinal tumors. [books.google.com]

Although three cases of pituicytoma with elevated plasma adrenocorticotropic hormone (ACTH) have been reported previously, the etiological mechanisms remain unknown. [file.scirp.org]

Little is known of the etiology or genetics (J. Neurosurg. 98 : 162, 2003). Grossly, most of these tumors usually filled with little cysts that contain an unsavory, cholesterol-rich fluid ("machine oil"). [pathguy.com]

Epidemiology PTs had a higher prevalence in the fifth and sixth decades of life, with a slight male predominance. 6). [operativeneurosurgery.com]

However, the epidemiology is not well known because of low incidence of the tumor. The clinical symptoms of pituicytomas are variable according to tumor size and location. [btrt.org]

[…] pituitary { 02294 } anterior pituitary, histology; curious stain, don't worry about the colors { 14948 } posterior pituitary, histology (arrow: Herring body) OBJECTIVES; Know when to suspect each of these clinical syndromes, and give the likely etiologies, pathophysiology [pathguy.com]

We removed the suprasellar tumor by the transcranial approach to decompress the optic nerves and chiasm to prevent permanent visual loss after angiography and recognition of the unusual pathology. [btrt.org]

POU1F prevents productions of GH, prolactin, and TSH (J. Clin. Endo. Metab. 90 : 4762, 2005). Even ACTH usually is insufficient: J. Clin. Endo. Metab. 89 : 5256, 2004. [pathguy.com]

At present, most patients are treated as having a clinically nonfunctioning adenoma, and the therapeutic goals are restoration of visual deficits, preservation of pituitary function, and prevention of recurrence. [15] Null cell adenomas and oncocytomas [emedicine.medscape.com]