Objective: We present a case of pityriasis rotunda in a 44-year-old African-Canadian woman who presented to a community dermatology practice in Toronto. Results: Pityriasis rotunda has been well described in Japan, Italy, and South Africa. [semanticscholar.org]

scaly lesions on his forearms that had been present for several months. [escholarship.org]

It has been associated with systemic diseases and malignant tumors, though many cases present no associated disorders.1 We present a case of intense PR associated with hyperprolactinemia. [actasdermo.org]

We report the case of a 20-year old male Congolese presenting with PR and ichthyosis vulgaris. This rarely described association raises the problem, discussed here, of whether PR belongs to ichthyosis vulgaris. [unboundmedicine.com]

Case Report A 7-year-old female presented to us with a 6-month history of an asymptomatic, dry, scaly circular lesion over the left arm. [ijpd.in]

• Recurrent Respiratory Infection

  Pityriasis rotunda with recurrent respiratory infections. G Ital Dermatol Venereol. 2017 Apr;152(2):190-191. [PubMed: 28166620] 4. Lefkowitz EG, Natow AJ. Pityriasis Rotunda: A Case Report of Familial Disease in an American-Born Black Patient. [ncbi.nlm.nih.gov]

• Weight Loss

  A review of systems was negative for fever, chills, shortness of breath, headache, abdominal pain, or weight loss. A punch biopsy was obtained for further diagnosis. [escholarship.org]

• Chills

  A review of systems was negative for fever, chills, shortness of breath, headache, abdominal pain, or weight loss. A punch biopsy was obtained for further diagnosis. [escholarship.org]

• Chronic Diarrhea

  […] infections Heart disease Female genital tract anomalies (ovarian cyst and fibroids) Glucose-6-phosphate dehydrogenase deficiency (favism) Chronic diarrhea Scleroderma Sarcoidosis Hormonal disorders such as hyperprolactinemia. [ncbi.nlm.nih.gov]

• Abdominal Pain

  A review of systems was negative for fever, chills, shortness of breath, headache, abdominal pain, or weight loss. A punch biopsy was obtained for further diagnosis. [escholarship.org]

• Skin Disease

  Abstract Pityriasis rotunda (PR) is a well-known skin disease in Japan, but it is seldom observed in Europe. [unboundmedicine.com]

  Overview Pityriasis rotunda is a rare skin disease characterized by round, scaly, pigmented patches that mainly occur on the trunk, arms and legs. There are two types of pityriasis rotunda. [rarediseases.org]

  […] authorHussein Odeibat MD, Department of Dermatology, Venereology and Laser, Laser King Hussein Medical Center, Amman, Jordan Search for more papers by this author First published: 17 May 2018 Citations: 4 Abstract Background Pityriasis rotunda is a rare skin [onlinelibrary.wiley.com]

  Lesions are usually darker than surrounding skin (hyperpigmented) in patients with dark skin and lighter (hypopigmented) in patients with light skin. [dermnetnz.org]

  These individuals do not have any associated malignancy or systemic diseases, but have multiple lesions that are lighter (hypopigmented) than the surrounding skin. [rarediseases.info.nih.gov]

• Nummular Dermatitis

  Pityriasis rosea: exanthematous, inflammatory, small focal plaques with typical scaling Nummular dermatitis: derb infiltrated, itching, scaly, possibly weeping. Subacute disease. [altmeyers.org]

• Hepatocellular Carcinoma

  Discover the latest research on Hepatocellular Carcinoma here. [meta.org]

  Pityriasis rotunda is a disorder of keratisation of the skin that manifests as a perfectly circular, scaly patches on the torso and proximal portions of the extremities.[1] It may be associated with diseases like hepatocellular carcinoma in racially predisposed [wikiwand.com]

  carcinoma in racially predisposed groups.[3] See also[edit] Skin lesion List of cutaneous conditions References[edit] ^ a b James, William; Berger, Timothy; Elston, Dirk (2005). [en.wikipedia.org]

  Hepatocellular carcinoma and cirrhosis were excluded. The patient was not able to establish the source of possible viral transmission. [x-mol.com]

There is no specific treatment for pityriasis rotunda. Lesions usually improve or resolve with treatment of the underlying internal disease or malignancy. [dermnetnz.org]

She reported no associated symptoms or previous treatment. [actasdermo.org]

Treatment of the disease can be challenging, and several different pharmacological treatments have been tried with limited success. [karger.com]

There is no specific treatment for pityriasis rotunda. [rarediseases.info.nih.gov]

They rarely itch, slowly enlarge, and coalesce and may be hypo- or hyper-pigmented.[2],[3],[4] Onset in childhood has been reported to have a better prognosis, with remission in later childhood in almost 50%.[6] Lesions are commonly seen on the buttocks [ijpd.in]

They rarely itch, slowly enlarge, and coalesce and may be hypo- or hyper-pigmented.[234] Onset in childhood has been reported to have a better prognosis, with remission in later childhood in almost 50%.[6] Lesions are commonly seen on the buttocks, thighs [journals.lww.com]

The prognosis for pityriasis rotunda is excellent. [emedicine.medscape.com]

Discussion The etiology of pityriasis rotunda remains unknown. [ijpd.in]

Figure 1: Single well-defined circular, scaly macule over the arm Discussion The etiology of pityriasis rotunda remains unknown. [journals.lww.com]

The etiology of pityriasis rotunda remains unknown, and the diagnosis is usually based on clinical examination. Importantly, the condition is often associated with underlying malignancies and chronic diseases or infections. [karger.com]

Pityriasis rotunda, not commonly encountered in some regions of the world, is not always easy to diagnose.[1][2][3] Etiology The etiology of pityriasis rotunda is not established. [ncbi.nlm.nih.gov]

Clinical and epidemiological study and follow-up on 47 cases observed in north Sardinia (1981-1995). Ena P., Chiarolini F., Gallus D., Spano G., Masotti A., Leigheb G. Università degli Studi - Sassari, Istituto di Clinica Dermatologica Background. [minervamedica.it]

Occurrence/Epidemiology This section has been translated automatically. w:m=3:1; several hundred patients have been described worldwide (Al-Refu et al. 2018). Etiopathogenesis This section has been translated automatically. [altmeyers.org]

However, researchers have not eliminated the idea that the association of some of these conditions associated with pityriasis rotunda, especially favism, could be due to chance.[4][5][6][7] Epidemiology Pityriasis rotunda affects both genders equally, [ncbi.nlm.nih.gov]

Pathophysiology The pathophysiology of pityriasis rotunda is still not completely understood. It may be a variant of ichthyosis vulgaris. [emedicine.medscape.com]

Pathophysiology Hashimoto et al. described a diminished expression of loricrin and filaggrin in pityriasis rotunda lesions. According to Yoneda et al., a complete absence of the profilaggrin-N terminus domain is observed in the lesional skin. [ncbi.nlm.nih.gov]

/kg/day for 5 days, maximum 500 mg/day Acyclovir 400mg per os every 4 hours for 5 days 800mg per os s 5 times per day Phototherapy UVB 5 times/week Special cases Children with severe pruritus Methylprednisolone 16mg/day Pregnant women: acyclovir may prevent [revistas.unal.edu.co]