The patient presented with a disorder of sexual differentiation (DSD) and 46, XX karyotype. [endopedonline.com.ar]

Affected males, on the other hand, do not present with obvious defects at birth, so are diagnosed much later in life, presenting with clinical symptoms, which include tall stature, delayed skeletal maturation, delayed epiphyseal closure, bone pain, eunuchoid [ncbi.nlm.nih.gov]

The present report reviews the various phenotypes of hyperandrogenism during pregnancy and its origin, pathophysiology, and the effect of hyperandrogenism on the fetal developmental trajectory and offspring consequences. [scholars.opb.msu.edu]

Both ovarian and testicular tissue present, ambiguous genitalia Defective androgen receptor Testosterone secreting tumor Exogenous Steroid use Hypogonadotropic hypogonadism ↓ Testosterone & ↓ LH Kallman Syndrome Ovaries are present, but the external genitalia [quizlet.com]

Case presentation A 26-year-old primigravida presented at 27 weeks of gestation with symptoms of facial and abdominal hirsutism, deepening of the voice and facial acne. [edmcasereports.com]

• Thyroid Nodule

  nodules; and new coverage of when and when not to use radioiodine in the treatment of patients with thyroid cancer. [books.google.com]

• Euthyroid

  Physical examination at 2.4 years old Weight: 14 kg (1.01 SDS) Length: 91 cm (0.55 SDS) No dysmorphic features, clinically euthyroid, in good general condition. [endopedonline.com.ar]

Following the examination by the family’s pediatrician, female pseudohermaphroditism was suspected, and a comprehensive workup was initiated. The hormonal changes in the mother before and after delivery are reported in Table 2. [academic.oup.com]

Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. [books.google.com]

Clinical efficacy of lower dose flutamide 125 mg/day in the treatment of hirsutism. J Endocrinol Invest 22: 165, 1999. PubMed CrossRef Google Scholar 21. Vigersky RA, Mehlman I, Glass AR, Smith CE. Treatment of hirsute women with cimetidine. [link.springer.com]

Conceptually, however, it is simplest to think of these causes in terms of the histology of the infant's gonads, which determines the prognosis with regard to fertility and pubertal development ( Table 2 ). [pediatrics.aappublications.org]

Chem. (2004) [ Pubmed ] High expression of steroid sulfatase mRNA predicts poor prognosis in patients with estrogen receptor-positive breast cancer. Miyoshi, Y., Ando, A., Hasegawa, S., Ishitobi, M., Taguchi, T., Tamaki, Y., Noguchi, S. Clin. [wikigenes.org]

The incidence and prevalence of ambiguous genitalia has not been as well documented as some other medical conditions because of the numerous varying etiologies. [gwumc.edu]

A retrospective study by Elhassan et al indicated that in women with androgen excess, the pattern of excess varies according to the etiology. [emedicine.medscape.com]

By contrast, with the exception of epidemiological studies assessing breast cancer risk and other scientific studies, the main value of E3 measurements is in the diagnosis of maternal-fetal diseases. [mayomedicallaboratories.com]

[…] major books: (1) Toxicology of Organophosphate and Carbamate Compounds, (2) Veterinary Toxicology: Basic and Clinical Principles, (3) Handbook of Toxicology of Chemical Warfare Agents, (4) Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology [books.google.it]

In premenopausal women, polycystic ovary syndrome was the primary cause of severe DHEAS excess. [24] Epidemiology Frequency United States The prevalence of androgen excess is 8%. [emedicine.medscape.com]

Covers the full spectrum of reproductive pathophysiology and disorders, from pregnancy and birth to reproductive aging. Includes the work of leaders in the field of reproductive endocrinology for guidance you can trust. [books.google.com]

The present report reviews the various phenotypes of hyperandrogenism during pregnancy and its origin, pathophysiology, and the effect of hyperandrogenism on the fetal developmental trajectory and offspring consequences. [scholars.opb.msu.edu]

Assessing estrogen metabolism, estrogen and estrogen-like medications, and other endogenous or exogenous factors impacting on estrogen metabolism in the context of other basic scientific and clinical studies Clinical Information Discusses physiology, pathophysiology [mayomedicallaboratories.com]

Hyperandrogenism, insulin resistance, and acanthosis nigricans syndrome: a common endocrinopathy with distinct pathophysiologic features. Am J Obstet Gynecol. 1983 Sep 1. 147(1):90-101. [Medline]. Legro RS. [emedicine.medscape.com]

Yet a lack of aromatase in the breast tissue induces a positive result by preventing estrogen dependent breast cancer. [www-personal.umd.umich.edu]

This conversion in the placenta prevents androgens from directing sexual development in female fetuses. After birth, the conversion of androgens to estrogens takes place in multiple tissues. [ghr.nlm.nih.gov]

Animal studies have demonstrated a role for estrogen in preventing the formation of new atherosclerotic plaques, but this role has not yet been demonstrated in humans. Androgens Arch Intern Med. 2006 Jul 10;166(13):1380-8. [pathophys.org]

There is a good reason for this: in the first days of pregnancy, corticotrophin-releasing hormone suppresses the mother’s immune system, preventing the mother’s body from attacking the foetus. [slideshare.net]

It is important to prevent these symptoms of adrenal crisis. Evaluation of serum electroytes and urinary excretion of sodium and potassium should be obtained daily until salt-wasting CAH can be ruled in or out. [gwumc.edu]