Presentation
A case of near full-term abortion involving a Friesian mare in the Pretoria district of Gauteng Province in South Africa during February 2000, with the same placental lesion as described in the Kentucky cases, is presented. [jsava.co.za]
These data are presented in light of current theories of fetal viral immunity. [ncbi.nlm.nih.gov]
42 37+6 5–10 75–90 95% Present 43 34+2 5–10 90–95 10% Present 44 31 25–50 25–50 Absent Present 45 37+3 25–50 75–90 75–80% Present 46 37+3 <3 >97 10% Present 47 (TWIN) 28+5 25–50 75–90 40% Present 48 (TWIN) 28+5 25–50 75–90 40% Present 49 31+6 50–75 50 [thelancet.com]
The present report demonstrates that the progesterone level and CTUP may be adequate as early diagnostic markers of fungal placentitis and bacterial infection. [jlc.jst.go.jp]
Entire Body System
- Sepsis
They still carry a risk for sepsis and orthopaedic complications. Treatment: Treatment of placentitis is often unrewarding, when the mare has developed clinical signs. [myeventflo.com]
Infection of the placenta results in subsequent infection of the fetus and in the release of prostaglandins from the inflamed placenta, which ultimately leads to abortion or delivery of a premature foal with bacterial sepsis. [equine.ca.uky.edu]
Any foal born to a mare with placentitis (premature or not) should be treated as being at a high risk of sepsis and managed accordingly. [beh.com.au]
Depending on the stage of pregnancy the above clinical signs are followed by either abortion or the birth of a small, weak foal that may be infected (septic) or develop sepsis. [riverinaequinevet.com.au]
- Falling
Total maternal plasma progestins are low until the last 2-3 weeks of gestation, climb substantially, and then fall abruptly within 24 hours of parturition. [theequinereport.com]
January 2022]) Persistent placental infection after maternal recovery has been described in case reports, with potential for placental compromise (Cell Prolif 2021;54:e13091, Viruses 2021;13:2545) Pathophysiology Pregnancies affected by COVID infection fall [pathologyoutlines.com]
Crossref PubMed Scopus (17) Google Scholar Ethics The Department of Clinical Governance considered that the study did not fall under the category of original research as no investigations were undertaken for research purposes and there was no control [thelancet.com]
- Hypothermia
Bradycardia and hypothermia was observed at 48 hours of life in No Survivors Group. Foals from No Survivors and Healthy groups showed leukopenia at birth with slight variations until 48h. [scielo.br]
- Malaise
After five days of malaise she spontaneously delivered a stillborn infant; she became acutely ill during the immediate postpartum period with septicaemic shock, acute renal failure, and disseminated intravascular coagulation. [ncbi.nlm.nih.gov]
Respiratoric
- Pneumonia
Bacterial agents commonly associated with the occurrence of placentitis includeStreptococcus equisubspecieszooepidemicus,Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa, Leptospiraspp, nocardioform bacteria (Crossiella equi, Amycolatopsis [equine.ca.uky.edu]
Foetus: fresh, minimal autolysis, pneumonia, hepatitis Placenta, foetus Diagnosis: identification in stained smears of the placenta or by ELISA, fluorescent antibody staining, PCR, or isolation in embryonated chicken eggs or cell culture. [partners-in-reproduction.com]
Klebsiella pneumoniae and alpha-hemolytic Streptococcus Streptococcus spp. [vetstream.com]
Bacterial agents commonly associated with the occurrence of placentitis include Streptococcus equi subspecies zooepidemicus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Leptospira spp, nocardioform bacteria ( Crossiella equi, Amycolatopsis [equimanagement.com]
Bacterial agents commonly associated with the occurrence of placentitis include Streptococcus equi subspecies zooepidemicus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Leptospira spp, nocardioform bacteria (Crossiella equi, Amycolatopsis [horsetalk.co.nz]
Gastrointestinal
- Abdominal Pain
陣痛 laparoscopy腹腔鏡検査 last menstrual period最終月経 late deceleration遅発一過性徐脈 leiomyosarcoma of the uterus子宮平滑筋肉腫 length of the fundus uteri子宮底長 lower abdominal pain下腹[部]痛 lower back pain腰痛 lumbago腰痛 luteinizing hormone (LH)黄体化ホルモン m maintenance chemotherapy [tokyo-med.ac.jp]
Fetus
- Placental Disorder
disorders, first trimester O43892Other placental disorders, second trimester O43893Other placental disorders, third trimester O4391Unspecified placental disorder, first trimester O4392Unspecified placental disorder, second trimester O4393Unspecified [cms.gov]
Urogenital
- Cervical Incompetence
Anatomical, hormonal or even neurological factors contributing to cervical incompetence and/or increased perineal or vaginal contamination will increase the risk of ascending placentits. [myeventflo.com]
In mares that are considered high risk (those that have a history of previous feto-placental compromise, cervical incompetency/lacerations, chronic disease, old age, poor reproductive conformation), routine placental ultrasonographic evaluations, in conjunction [info.selectbreeders.com]
[…] cancer子宮頸癌 cervical gland子宮頸管腺 cervical incompetency頸管無力症 cervical intraepithelial neoplasia (CIN)子宮頸部上皮内腫瘍 cervicitis子宮頸管炎 cesarean delivery帝王切開による分娩 cesarean section帝王切開 chemotherapy化学療法 Chlamydia trachomatisクラミジア トラコマテイス choriocarcinoma絨毛癌 chromosomal [tokyo-med.ac.jp]
Workup
Serum
- Leukopenia
Foals from No Survivors and Healthy groups showed leukopenia at birth with slight variations until 48h. Foals born from mares with ascending placentitis and treated showed distinct clinical and neonatal responses. [scielo.br]
Microbiology
- Pseudomonas
Leptospirosis spp., Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus, Streptococcus and Salmonella abortus equi are bacteria that can enter by this mechanism. [info.selectbreeders.com]
Bacterial agents commonly associated with the occurrence of placentitis includeStreptococcus equisubspecieszooepidemicus,Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa, Leptospiraspp, nocardioform bacteria (Crossiella equi, Amycolatopsis [equine.ca.uky.edu]
Common bacteria implicated are Streptococcus, Klebsiella, E.coli and Pseudomonas. Fungal infection is also possible. [beh.com.au]
[…] aeruginosa Pseudomonas aeruginosa, S. equisimilis, Enterobacter agglomerans, Klebsiella pneumoniae Klebsiella pneumoniae and alpha-hemolytic Streptococcus Streptococcus spp. [vetstream.com]
- Gram-Positive Rods
Numerous colonies of small, pleomorphic, Gram-positive, rod-shaped bacteria were observed within the fibrin lattice associated with placental lesions and within the fetal atelectatic lung. [works.bepress.com]
Treatment
Thereafter, placentitis induced mares were randomly assigned into: (1) basic treatment, TMS+FM (n = 8); (2) basic treatment with ALT supplementation, TMS+FM+ALT (n = 8); (3) basic treatment with ECP supplementation, TMS+FM+ECP (n = 6); (4) basic treatment [experts.illinois.edu]
Currently, ultrasonographic evaluation of the placenta is used to detect early cases of placentitis and to implement treatment to prevent abortion and delay premature labor. [equine.ca.uky.edu]
Future studies will hopefully identify markers of infection and inflammation characteristic for placentitis so treatment can be initiated early. [info.selectbreeders.com]
Treatment The treatment for placentitis is primarily aimed at controlling infection and reducing inflammation. [beh.com.au]
More effective prenatal treatment of mares is essential to reduce the incidence of premature delivery of compromised foals. [agrifutures.com.au]
Prognosis
PROGNOSIS AND RELEVANT FACTORS The prognosis is generally poor. It is difficult to control the infection and maintain a healthy pregnancy. my role I might observe You might make these observations when a horse has this condition. [horsesidevetguide.com]
Pathophysiology is emphasized throughout, providing a sound basis for discussions of the diagnosis, treatment, and prognosis that follow. [books.google.com]
Most foals that present with these symptoms have a very poor prognosis but Fiona fought every step of the way and responded to treatment. [belvoirequineclinic.com.au]
Prognosis If the condition is diagnosed early and aggressive treatment initiated with a combination of broad spectrum antibiotics, altrenogest and non-steroidal anti-inflammatory medication, up to 73% of mares may deliver live foals. [beh.com.au]
Etiology
Placental villitis of unknown etiology: Harbinger of serious disease? a four month's experience of nine cases. Journal of Reprodutive Medicine 11:215- 222, 1973. 3. Altschuler G, Russel P. [scielo.br]
This study was conducted to compare C4d immunoreactivity between villitis of unknown etiology (VUE) and cytomegaloviral placentitis. C4d immunohistochemistry was performed in cases with VUE (n = 16) and cytomegaloviral placentitis (n = 5). [ncbi.nlm.nih.gov]
In another 24 placentas they observed only villitis in the absence of parasitism determining a frequency of 17.9% of villitis of unknown etiology. A control group of placentas of non chagasic mothers was studied. [scienceopen.com]
The minimal diagnostic features required for COVID placentitis are Chronic histiocytic intervillositis and trophoblast necrosis and documentation of recent maternal infection via nasal swab Chronic villitis of uncertain etiology (VUE) with documented [pathologyoutlines.com]
@article{Hong1993EtiologyAP, title={Etiology and pathology of equine placentitis.}, author={Chuen Bin Hong and James M. Donahue and R. C. Giles and Marie B. Petrites-Murphy and Kockanda B Poonacha and Alex. Roberts and Bonnie J. [semanticscholar.org]
Epidemiology
It also addresses the importance of preventing and controlling infectious disease outbreaks with coverage of epidemiology, biosecurity, antimicrobial therapy, and recognizing foreign equine diseases. [books.google.de]
Director & Professor of Epidemiology at the University of Kentucky's Veterinary Diagnostic Laboratory (UKVDL) in Lexington, Kentucky issued a notice to area veterinarians today that the UKVDL received an equine fetus from a Bluegrass area farm. [equusmagazine.com]
This study followed applicable sections of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) reporting guideline. [jamanetwork.com]
Diagnostic epidemiology of nocardioform placentitis and abortion in Kentucky, 1991-2015. Craig N. Carter, Erdal Erol, Noah D. Cohen, and Jacqueline L. Smith. 2016, J Equine Vet Sci. Vol 39, S59-S60. [derbybarandgrill.com]
Newly recognized species such as N. africana, N. paucivorans, and N. veterana have also been reported to cause disease in humans, although little is known of their epidemiology (6, 8, 13). [ncbi.nlm.nih.gov]
Pathophysiology
Pathophysiology is emphasized throughout, providing a sound basis for discussions of the diagnosis, treatment, and prognosis that follow. [books.google.com]
The expression of the inflammatory cytokines such as IL-1β, IL-6, IL-8 and TNF-α increase in case of infection.These cytokines may play an essential role in the pathophysiology of spontaneous pretem labor with intact membrane.An observational analytic [mji.ui.ac.id]
231369427 Diesen Titel auf die Merkliste setzen In vivo : international journal of experimental and clinical pathophysiology and drug research / International Institute of Anticancer Research Kapandriti, Attiki : IIAR Nachgewiesen 18.2004 - Titel In [zdb-katalog.de]
LeBlanc M M, Macpherson M & Sheerin P (2004) Ascending Placentitis: What we Know About Pathophysiology, Diagnosis and Treatment. In: Proc 50th Annual Convention of the AAEP. Denver, USA. [vetstream.com]
Prevention
Ideal for both practitioners and students, this comprehensive resource covers the diagnosis, treatment, and prevention of infectious disease in horses. [books.google.de]
To prevent abortion, early detection of the condition is critical and waiting until clinical signs of placentitis develop may be too late. [veterinarypartner.vin.com]
Thickening at the cervical star can prevent it rupturing at birth or abortion, so that the chorion tears across the rostral body. [myeventflo.com]
Pregnant women with COVID-19 have an increased risk for stillbirth compared to uninfected women, and those who vaccinate can more effectively prevent adverse conditions such as SARS-CoV-2 placentitis, infant death, preterm birth, and stillbirth. [massgeneral.org]
Management Management and prevention of placentitis involves a number of factors. For viral abortion ( EHV ) this means vaccination of mares in their 5th, 7th and 9th months of pregnancy. [longfordequine.com.au]