behavior Irritability Neoplasm of the skin Fine hair Azoospermia Aminoaciduria Nephrocalcinosis Joint contracture of the hand Skin ulcer Clonus Stereotypy Nephrolithiasis Hypoplasia of dental enamel Subcutaneous nodule Open mouth Dehydration Joint stiffness [mendelian.co]

These include neurofibrillary tangles, amyloid plaques, neuroinflammation, hypomyelination, neuronal shrinkage (eg. [semanticscholar.org]

Amyloid lowering drugs are currently in development and clinical trials for removing the accumulation or to reduce the production of amyloid plaques. [google.com]