Presentation
And 5 weeks after the completion of treatment, he presented with fever and diagnosed as P. ovale infection. P. ovale infection is a rare cause of malaria and often shows delayed presentation due to its dormant liver stage as hypnozoites. [ncbi.nlm.nih.gov]
No mixed infections were identified in which both species were present. [doi.org]
Entire Body System
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Laboratory Technician
The current finding should serve as an alert to epidemiologists, clinicians and laboratory technicians in the possibility of finding P. ovale in Malaysia. [ncbi.nlm.nih.gov]
Obare P, Ogutu B, Adams M, Odera JS, Lilley K, et al. (2013) Misclassification of Plasmodium infections by conventional microscopy and the impact of remedial training on the proficiency of laboratory technicians in species identification. [journals.plos.org]
Liver, Gall & Pancreas
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Scleral Icterus
Examination demonstrated scleral icterus, splenomegaly, and anemia. By peripheral blood smear, the patient was diagnosed with Plasmodium ovale. [ncbi.nlm.nih.gov]
Psychiatrical
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Suggestibility
The recent increase in the number of people travelling to regions where P. ovale is endemic, suggests that a PCR-based protocol should be included as a complementary tool for malaria reference laboratories. [ncbi.nlm.nih.gov]
Urogenital
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Renal Injury
This is by far the first reported case of P. ovale infection with acute renal injury. In case B, the patient suffered renal injury a few days before he came down with nosocomial sepsis. [link.springer.com]
Workup
A sepsis workup was performed including blood- and urine culture, and a microscopic examination of the urine sediment. Because of maternal malaria infection, malaria screening of the neonate was included. [pediatric-infectious-disease.imedpub.com]
X-Ray
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Bilateral Pulmonary Infiltrate
On the second day of treatment the patient developed respiratory failure, requiring intubation and ventilatory support with new bilateral pulmonary infiltrates. [ncbi.nlm.nih.gov]
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Pulmonary Infiltrate
On the second day of treatment the patient developed respiratory failure, requiring intubation and ventilatory support with new bilateral pulmonary infiltrates. [ncbi.nlm.nih.gov]
Serum
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Lymphocytopenia
Laboratory tests showed anaemia (haemoglobin 11.4 g/dl), severe thrombocytopaenia (platelets 30 10(9)/mm(3)), leukopenia (3650/mm(3)), lymphocytopenia (650/mm(3)). [ncbi.nlm.nih.gov]
Treatment
According to the hospital's malaria treatment guidelines for severe malaria, treatment consisted of intravenous quinine at hour 0 (start of treatment) and 24 h after initial treatment, followed by artemether-lumefantrine 24 h later. [ncbi.nlm.nih.gov]
Etiology
In conclusion, P. ovale should be considered as an etiology in the imported malaria in Korea, because the number of travelers to P. ovale endemic regions has recently increased. [ncbi.nlm.nih.gov]
Manifestation code identifies conditions for which it is important to record both the etiology and the symptom of the disease. [books.google.es]
[…] by fever, anemia and splenomegaly and is caused by apicomplexan parasites of the genus Plasmodium Epidemiology P. vivax and P. ovale are the least frequent of malaria species; most cases arise in Western Africa, India, South America Pathophysiology / etiology [pathologyoutlines.com]
Epidemiology
Additional epidemiological data were taken from a database of 1045 imported cases. None. [ncbi.nlm.nih.gov]
Research on the epidemiology and control of malaria in the Sudan savanna of West Africa, 1980 Geneva World Health Organization Rogier et al., 1996 Evidence for an age-dependent pyrogenic threshold of Plasmodium falciparum parasitemia in highly endemic [doi.org]
Pathophysiology
The epidemiology of mixed infections, likely pathophysiology of his presentation, and the implications for malaria testing and treatment in returned travellers are discussed. [ncbi.nlm.nih.gov]
The pathophysiology of P. falciparum as the leading cause of severe malaria has been examined extensively. [malariajournal.biomedcentral.com]
[…] characterized clinically by fever, anemia and splenomegaly and is caused by apicomplexan parasites of the genus Plasmodium Epidemiology P. vivax and P. ovale are the least frequent of malaria species; most cases arise in Western Africa, India, South America Pathophysiology [pathologyoutlines.com]
Prevention
However, it remains possible that localised geographic, temporal or ecological barriers exist within endemic countries which prevent recombination between the genomes of the two species. [ncbi.nlm.nih.gov]