And 5 weeks after the completion of treatment, he presented with fever and diagnosed as P. ovale infection. P. ovale infection is a rare cause of malaria and often shows delayed presentation due to its dormant liver stage as hypnozoites. [ncbi.nlm.nih.gov]

No mixed infections were identified in which both species were present. [doi.org]

• Dry Cough

  He reported shaking chills, nausea and dry cough. Fever episodes occurred every 48 hours, with profuse sweating followed by abrupt resolution. He had no other significant medical history. On presentation, he was pale. [latunisiemedicale.com]

• Scleral Icterus

  Examination demonstrated scleral icterus, splenomegaly, and anemia. By peripheral blood smear, the patient was diagnosed with Plasmodium ovale. [ncbi.nlm.nih.gov]

• Suggestibility

  The recent increase in the number of people travelling to regions where P. ovale is endemic, suggests that a PCR-based protocol should be included as a complementary tool for malaria reference laboratories. [ncbi.nlm.nih.gov]

  The genome suggests that P. malariae expresses a family of heterodimeric proteins on its surface that have structural similarities to a protein crucial for invasion of red blood cells. [bdi.ox.ac.uk]

• Renal Injury

  In case B, the patient suffered renal injury a few days before he came down with nosocomial sepsis. Therefore, the acute renal injury seen in this case was less likely to be caused by nosocomial sepsis. [link.springer.com]

A sepsis workup was performed including blood- and urine culture, and a microscopic examination of the urine sediment. Because of maternal malaria infection, malaria screening of the neonate was included. [pediatric-infectious-disease.imedpub.com]

• Bilateral Pulmonary Infiltrates

  On the second day of treatment the patient developed respiratory failure, requiring intubation and ventilatory support with new bilateral pulmonary infiltrates. [ncbi.nlm.nih.gov]

• Pulmonary Infiltrate

  On the second day of treatment the patient developed respiratory failure, requiring intubation and ventilatory support with new bilateral pulmonary infiltrates. [ncbi.nlm.nih.gov]

According to the hospital's malaria treatment guidelines for severe malaria, treatment consisted of intravenous quinine at hour 0 (start of treatment) and 24 h after initial treatment, followed by artemether-lumefantrine 24 h later. [ncbi.nlm.nih.gov]

treatment and by 33% ( p = 0.015) compared to no treatment [ 27 ]. [journals.plos.org]

Sections Continuing Education Activity Introduction Etiology Epidemiology Pathophysiology Histopathology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Pearls and Other Issues Enhancing Healthcare [pubmed.ncbi.nlm.nih.gov]

In conclusion, P. ovale should be considered as an etiology in the imported malaria in Korea, because the number of travelers to P. ovale endemic regions has recently increased. [ncbi.nlm.nih.gov]

[…] by fever, anemia and splenomegaly and is caused by apicomplexan parasites of the genus Plasmodium Epidemiology P. vivax and P. ovale are the least frequent of malaria species; most cases arise in Western Africa, India, South America Pathophysiology / etiology [pathologyoutlines.com]

Etiology Malaria is caused by obligate intracellular protozoan parasites of the genus "Plasmodium". The four species of human malarial parasites are Plasmodium vivax, P falciparum, P malariae, and P ovale. [atsu.edu]

Additional epidemiological data were taken from a database of 1045 imported cases. None. [ncbi.nlm.nih.gov]

Research on the epidemiology and control of malaria in the Sudan savanna of West Africa, 1980 Geneva World Health Organization Rogier et al., 1996 Evidence for an age-dependent pyrogenic threshold of Plasmodium falciparum parasitemia in highly endemic [doi.org]

The epidemiology of mixed infections, likely pathophysiology of his presentation, and the implications for malaria testing and treatment in returned travellers are discussed. [ncbi.nlm.nih.gov]

The pathophysiology of P. falciparum as the leading cause of severe malaria has been examined extensively. [malariajournal.biomedcentral.com]

[…] characterized clinically by fever, anemia and splenomegaly and is caused by apicomplexan parasites of the genus Plasmodium Epidemiology P. vivax and P. ovale are the least frequent of malaria species; most cases arise in Western Africa, India, South America Pathophysiology [pathologyoutlines.com]

However, it remains possible that localised geographic, temporal or ecological barriers exist within endemic countries which prevent recombination between the genomes of the two species. [ncbi.nlm.nih.gov]

Intermittent preventive treatment for the prevention of malaria during pregnancy in high transmission areas. Malar J. 2007 Dec 4. 6:160. [Medline]. [Full Text]. Trape JF, Tall A, Diagne N, et al. [medscape.com]