Presentation
Such adhesion will not occur so long as fibrine is present on the surface, and is to be carefully distinguished from the mere glueing which may occur in the earlier stages from the adhesion of the fibrinous exudation on opposed surfaces. [chestofbooks.com]
Tissues present include: Pleura, adipose tissue, skeletal muscle, nerves and lung parenchyma. [histopathology-india.net]
/or purulent (empyema) Thoracentesis necessary to differentiate Cancer Most commonly lung cancer, breast cancer, or lymphoma but possible with any tumor metastatic to pleurae Typically causing dull, aching chest pain Pulmonary embolism Effusion present [merckmanuals.com]
Pleural TB was present in 31 cases (24%) on histopathology. Only 3 patients had AFB positivity on pleural biopsy. [lungindia.com]
Six consecutive patients with tuberculous pleural effusions are here presented. Diagnosis was established with the aid of tuberculin test, cultures of gastric washings and pleural fluid, and pleural biopsy. [pediatrics.aappublications.org]
Respiratoric
- Pleuritic Pain
Many cause dyspnea, pleuritic chest pain, or both. Pleuritic chest pain, a vague discomfort or sharp pain that worsens during inspiration, indicates inflammation of the parietal pleura. [merckmanuals.com]
Results: Time to resolution of symptoms Trial Indicator Units Corticosteroids Control Mean values Bang 1997 “Fever, pleuritic pain, malaise and breathlessness” Mean days to resolution 3.8 (N = 34) 7.4 1 (N = 50) Galarza 1995 “Fever duration” Mean days [cochranelibrary.com]
- Pleural Disorder
Egypt J Bronchol 2015;9:92-5 Introduction Medical thoracoscopy is now an established technique for diagnosis and management of various pleural disorders [1]. [ejbronchology.eg.net]
Cardiovascular
- Chest Pain
As the disease progresses, patients commonly experience chest pain and breathlessness (dyspnea). [asbestos.com]
Pleuritic chest pain, a vague discomfort or sharp pain that worsens during inspiration, indicates inflammation of the parietal pleura. Pain is usually felt over the inflamed site, but referred pain is possible. [merckmanuals.com]
During this period, 51 patients experienced mild but transient chest pain and fever, and 3 complained of severe chest pain and dyspnea (Table 2 ). [copdrp.biomedcentral.com]
If a patient is supine, then a pleural effusion layers along the posterior aspect of the chest cavity and becomes difficult to see on a chest X-ray. [radiologymasterclass.co.uk]
Workup
[…] pleural effusion, cytobiochemical analysis of pleural fluid is needed to establish the etiology; however, it is useful for diagnosis only in up to 60% of cases, [7] in around 20% of the cases, etiology often remains unclear even after extensive diagnostic workup [lungindia.com]
Preoperative workup included contrasted chest and abdominal CT, bronchoscopy, PFT, 18-FDG PET-scan. All procedures were performed under the general anesthesia with double-lumen tube intubation and single lung ventilation. [jtd.amegroups.com]
X-Ray
- Chest X-Ray Abnormal
Home » Tutorials » Chest X-ray Tutorials » Chest X-ray Abnormalities » Introduction » 1 2 3 4 5 6 7 8 9 10 11 » Conclusion Key points The pleura and pleural spaces are only visible when abnormal There should be no visible space between the visceral and [radiologymasterclass.co.uk]
- X-Ray Abnormal
Home » Tutorials » Chest X-ray Tutorials » Chest X-ray Abnormalities » Introduction » 1 2 3 4 5 6 7 8 9 10 11 » Conclusion Key points The pleura and pleural spaces are only visible when abnormal There should be no visible space between the visceral and [radiologymasterclass.co.uk]
Treatment
Endovascular aortic treatment is being performed more often and offers some advantages over open surgery. [ncbi.nlm.nih.gov]
EBV treatment has been shown to be a very effective treatment for patients with severe emphysema without collateral ventilation [ 14 ]. [karger.com]
Therefore, Thoracoscopy had the double roles of both diagnosis and treatment for pleural effusion. Pre-treatment of thoracoscopy provide further chance for malignant pleural effusion therapy. [gooddoctor.cc]
Control Placebo or no adjunctive treatment. Both treatment groups should receive the same antituberculous drug regimen. [cochranelibrary.com]
Prognosis
The presence of pleural adhesions in MPE implies a poor prognosis. [ncbi.nlm.nih.gov]
Considering the prognosis, pathologic p1–3 tumors should be managed as a T2 disease for the present. Keywords Lung cancer Surgery Pathology Pleural invasion Prognosis Staging This is a preview of subscription content, log in to check access. [link.springer.com]
Prognosis : depends on nature and cause of effusion, generally very guarded. [vetstream.com]
These additional studies may be useful in determining prognosis and optimal treatment for a given primary tumor, based on individual characteristics of the tumor. [shortnessofbreath.it]
Overall, the thymoma patients did better than the mesothelioma patients, probably due to their better prognosis. 32 Future Directions Clinicians are frustrated that treatment for patients with MPE has changed little since 1935. [jhoponline.com]
Etiology
Etiology prior trauma/surgery penetrating chest trauma (e.g. stabbing, gunshot wound) rib fractures surgical (e.g. pleurectomy) prior infective conditions pleurisy: tuberculosis, viral pulmonary tuberculosis pulmonary abscess empyema sequelae of vascular [radiopaedia.org]
No etiological factors had been detected during medical examinations. Chest-computed tomography showed localized bronchiectasis in the right upper lobe, and it was recommended that the patient undergo a VATS lobectomy. [ctsnet.org]
Main indication for thoracoscopy in this study was recurrent exudative pleural effusion, whose etiology remained unexplained after initial and repeated cytobiochemical analysis of pleural fluid. [lungindia.com]
The etiology is usually unknown, but heart failure, lymphoma, heart worm infection and lymphangiectasia are sometimes implicated. Timecourse Acute. Insidious and progressive. [vetstream.com]
Etiology is unknown for about 15% of effusions even after extensive study; many of these effusions are thought to be due to viral infection. [merckmanuals.com]
Epidemiology
Epidemiology Secondary Spontaneous Pneumothorax The incidence of secondary spontaneous pneumothorax depends on the underlying disease process. [what-when-how.com]
Pathophysiology
Pathophysiology [ edit ] Adhesions form as a natural part of the body’s healing process after surgery in a similar way that a scar forms. [en.wikipedia.org]
Pathophysiology Fluid accumulation in pleural space → lung lobes unable to expand → dyspnea. True transudates associated with hypoproteinemia. [vetstream.com]
More recently the interconnected causal relationships between TB, HIV, smoking, and chronic lung disease have been further elucidated, although many questions regarding pathophysiology remain unanswered ( van Zyl Smit 2010 ). [cochranelibrary.com]
Prevention
RESULTS: A significant reduction of adhesions in the PL+PG group (p CONCLUSIONS: PL+PG may be used to prevent pleural adhesions. The process of fibrinolysis, and fibrosis was though not affected after PLPG administration. [ncbi.nlm.nih.gov]
Prevention of Pleural Adhesions by Bioactive Polypeptides - A Pilot Study. Int J Med Sci 2013; 10(12):1720-1726. doi:10.7150/ijms.6651. Available from http://www.medsci.org/v10p1720.htm [medsci.org]
Recent advances in prevention and management". Digestive Surgery. 18 (4): 260–73. doi : 10.1159/000050149. [en.wikipedia.org]