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Pleural Fibrosis
Pleura Fibrosis

Presentation

Pleural fibrosis is the most common presentation of all asbestos fiber types. [libbyasbestos.org]

DISCUSSION Pleural, mediastinal and retroperitoneal fibrosis usually present as distinct entities. [thorax.bmj.com]

Intermittent pleural friction rubs have been present in all four; one patient showed pleural uptake of gallium-67. [ncbi.nlm.nih.gov]

Respiratoric

  • Pleural Disorder

    The nonneoplastic pleural disorders ascribed to asbestos include benign pleural effusion, plaques, and diffuse pleural fibrosis. Unexplained pleural effusions due to asbestos occur and may precede subsequent asbestos-related pleural disease. [cdc.gov]

Workup

Extensive workups including repeated pulmonary ventilation-perfusion scans and cardiac catheterisation have not yielded other diagnoses to explain the pain. [ncbi.nlm.nih.gov]

X-Ray

  • X-Ray Abnormal

    Chest X-ray abnormalities detected at the initial medical examination, and interpreted according to the International Labour Office Classification of Radiographs of Pneumoconioses are reported in this paper. [ncbi.nlm.nih.gov]

    Home » Tutorials » Chest X-ray Tutorials » Chest X-ray Abnormalities » Introduction » 1 2 3 4 5 6 7 8 9 10 11 » Conclusion Key points The pleura and pleural spaces are only visible when abnormal There should be no visible space between the visceral and [radiologymasterclass.co.uk]

  • Chest X-Ray Abnormal

    Chest X-ray abnormalities detected at the initial medical examination, and interpreted according to the International Labour Office Classification of Radiographs of Pneumoconioses are reported in this paper. [ncbi.nlm.nih.gov]

    Home » Tutorials » Chest X-ray Tutorials » Chest X-ray Abnormalities » Introduction » 1 2 3 4 5 6 7 8 9 10 11 » Conclusion Key points The pleura and pleural spaces are only visible when abnormal There should be no visible space between the visceral and [radiologymasterclass.co.uk]

  • Anterior Mediastinal Mass

    Three asbestos-exposed RPF patients had exceptionally large anterior pleural masses extending into the anterior mediastinum. [ojrd.biomedcentral.com]

Pleura

  • Pleural Adhesions

    […] without remodeling or fibrosis or could result in the development of adhesions, fibrosis, and destruction of the pleural membrane. [journals.lww.com]

    Diffuse pleural fibrosis, as opposed to pleural plaque, represents fibrous thickening of the parietal and/or visceral pleura often associated with dense pleural adhesions [McCloud et al. 1985]. [cdc.gov]

    One limitation of medical thoracoscopy is the limited visualisation of the pleural cavity in patients with significant pleural adhesions. [academic.oup.com]

Treatment

Serosal fibrosis is a rarely reported adverse effect of pergolide treatment, although it is well described with other dopamine agonists. [ncbi.nlm.nih.gov]

We also propose new potential therapies for the treatment of this disease. [grantome.com]

Updated to reflect the latest scientific advances and technologies in the diagnosis and treatment of pleural diseases, this new Second Edition explores the structure and function of these diseases and malignancies, from tuberculosis and asbestos to pleurisy [books.google.es]

Conditions that improve with immune suppressive treatment probably are not idiopathic pulmonary fibrosis. The toxicity and side effects of treatments can be serious. [medicinenet.com]

Prognosis

The prognosis for patients with pulmonary fibrosis varies, but the prognosis for mesothelioma is always bleak; most mesothelioma patients succumb to the disease within a year. [allaboutmalignantmesothelioma.com]

Treatment and prognosis Treatment options can range from conservative to surgical intervention with pleural decortication considered in selected cases 5. References Promoted articles (advertising) [radiopaedia.org]

High-resolution computed tomography in idiopathic pulmonary fibrosis: diagnosis and prognosis. American Journal of Respiratory and Critical Care Medicine 2005 ; 172 : 488 – 493. 11. Markowitz, SB, et al. [cambridge.org]

Etiology

The etiology of restrictive lung physiology in SLS is not well-defined, and has been hypothesized to be due to defects in lung recoil, phrenic nerve function and diaphragmatic strength. [ncbi.nlm.nih.gov]

The findings suggest a shared etiology for RPF and pleural fibrosis and furthermore possibly a similar pathogenetic mechanisms. [tampub.uta.fi]

The etiology of RPF is generally unknown. [ojrd.biomedcentral.com]

According to etiology it may be classified as: benign pleural thickening following recurrent inflammation following recurrent pneumothoraces following a pleural empyema as a delayed complication of a hemothorax collagen-vascular disease (rheumatoid arthritis [radiopaedia.org]

Epidemiology

Epidemiology of community-acquired pneumonia in adults: a population-based study. European Respiratory Journal 2000 ; 15 : 757 – 763. 14. Vila-Corcoles, A, et al. [cambridge.org]

The book integrates the newest research and advances in its discussions of the disease, covering such topics as carcinogenesis, epidemiology, benchwork, endoscopy, multimodality approaches and treatment. [books.google.es]

Department of Epidemiology and Health McGill University Canada 2. Respiratory Division of the Notre-Dame Hospital University of Montreal Canada 3. Respiratory Division McGill University Montreal Canada 4. [link.springer.com]

Pathophysiology

Wuhan, Hubei, China; Department of Respiratory and Critical Care Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China; 6 Key Laboratory of Respiratory Diseases, Ministry of Health of China, Wuhan, Hubei, China; Department of Pathophysiology [ncbi.nlm.nih.gov]

Chest 121:2079–2080 PubMed CrossRef Google Scholar Miserocchi G (1997) Physiology and pathophysiology of pleural fluid turnover. [link.springer.com]

The etiology and pathophysiology of this entity are unknown. [nature.com]

Prevention

In selected patients, resection of the histoplasmoma may be necessary to prevent impairment of ventilation from pleural fibrosis. [ncbi.nlm.nih.gov]

2) via targeting miR-26a by intrapleural gene therapy to prevent fibrosis in pleural empyema. [grantome.com]

In the present study, we found that tuberculous pleural effusion (TPE) induced calpain activation in PMCs and that inhibition of calpain prevented TPE-induced collagen-I synthesis and cell proliferation of PMCs. [augusta.pure.elsevier.com]

Surgery May Be Required When locutaion prevents fluid drainage, the standard of care is surgery to remove the scar tissue. [lungtx.com]

Fibrothorax is a time-dependent process and can be prevented. Depending on the cause, insertion of a chest tube to remove an effusion or hemothorax may prevent the development of fibrothorax. [emedicine.medscape.com]

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