This reference guide will be the must-have of any internist or medical professional, as it takes a vast quantity of data across a sweeping grid of disorders, diseases, and presentations, and boils them down to individual parts, facilely indexed, and located [books.google.de]

The results presented here supplement recent findings and, moreover, allow new conclusions to be made regarding both the structure-activity relationships, particularly with respect to the alkyl side chains, and the mechanism of action of aureolic acid [ncbi.nlm.nih.gov]

• Localized Pain

  Hepatic: Hepatotoxicity Local: Pain at injection site Extravasation: Is an irritant; may produce local tissue irritation or cellulitis if infiltrated; if extravasation occurs, follow hospital procedure, discontinue I.V., and apply ice for 24 hours Irritant [syrianclinic.com]

• Petechiae

  […] and thrombocytopenia WBC: Moderate, but uncommon Platelets: Moderate, rapid onset Onset (days): 7-10 Nadir (days): 14 Recovery (days): 21 Clotting disorders: May also depress hepatic synthesis of clotting factors, leading to a form of coagulopathy; petechiae [syrianclinic.com]

• Carpopedal Spasm

  Monitor patient for tetany, carpopedal spasm, Chvostek’s sign, and muscle cramps because a sharp drop in calcium levels is possible. • Watch for signs of bleeding. [glowm.com]

• Chvostek Sign

  Monitor patient for tetany, carpopedal spasm, Chvostek’s sign, and muscle cramps because a sharp drop in calcium levels is possible. • Watch for signs of bleeding. [glowm.com]

• Foul Smelling Urine

  Report persistent fever or chills, unhealed sores, oral or vaginal sores, foul-smelling urine, easy bruising or bleeding, yellowing of eyes or skin, or change in color of urine or stool. [syrianclinic.com]

In two patients treatment had to be discontinued due to severe toxicity. [ncbi.nlm.nih.gov]

Formerly called mithramycin. indications It is prescribed primarily in the treatment of malignant tumors of the testis. [medical-dictionary.thefreedictionary.com]

Do not receive "live" vaccines during treatment with plicamycin. Administration of a live vaccine may be dangerous during treatment with plicamycin. Other drugs may interact with plicamycin. [drugs.com]

A recently introduced antibiotic, mithramycin, has demonstrated striking antitumor activity in testicular neoplasms, especially the embryonal-cell carcinoma.Except for seminoma, there is a consistently poor prognosis for testicular neoplasms of germinal [doi.org]

Long-term survivors in chronic granulocytic leukaemia: a study by the International CGL Prognosis Study Group. Br J Haematol. 1994;87:293-300. 44. Kantarjian H, Talpaz M, O’Brien S, et al. [hematologyandoncology.net]

Cancer epidemiology in the last century and the next decade. Nature 2001 ; 411 : 390 –5. Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 1997 ; 277 : 815 –8. [doi.org]

Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. [drugs.com]

Vitamin D3 and calcium to prevent hip fractures in the elderly women. ‎ [books.google.de]