Symptoma

Poliovirus

Environmental surveillance (ES) can detect circulating polioviruses from sewage without relying on clinical presentation. [ncbi.nlm.nih.gov]

Racaniello * Present affiliation: Rockefeller University, New York. [doi.org]

Molecular serotyping conducted at PHOL should identify poliovirus if present. [publichealthontario.ca]

  • Hypertension

    14 (27) 8 (15) 4 (8) — — Seizure 19 (37) 2 (4) 1 (2) — 1 (2) Psychiatric disorder Confusion 3 (6) 5 (10) 1 (2) — — Delusions — — 1 (2) — — Hallucinations 1 (2) — — — — Renal and urinary disorder: urinary incontinence 1 (2) — — — — Vascular disorder: hypertension [nejm.org]

  • Bilateral Leg Weakness

    gypsy) girl from Bourgas, Bulgaria, had onset of bilateral leg weakness. The National Enterovirus Laboratory in the capital city of Sofia subsequently isolated a wild type 1 poliovirus in the patient's stool. [ncbi.nlm.nih.gov]

  • Neglect

    There is therefore the need to ensure that enterovirologist globally, especially those outside the global polio laboratory network, can participate in poliovirus surveillance without neglecting their enterovirus type of interest. [ncbi.nlm.nih.gov]

Diagnostic workup and treatment were performed in Italy. Poliovirus replicated in the gut for 7 months. The 5' non coding region (NCR), VP1, VP3 capsid proteins and the 3D polymerase genomic regions of sequential isolates were sequenced. [ncbi.nlm.nih.gov]

  • Chlamydia

    Analysis of synonymous codon usage bias in Chlamydia. Acta Biochim Biophys Sin (Shanghai) 2005; 37 :1–10. doi: 10.1093/abbs/37.1.1. [ PubMed ] [ CrossRef ] [ Google Scholar ] Wright F. The 'effective number of codons' used in a gene. [ncbi.nlm.nih.gov]

    Biologicals 2006, 34: 103-108. 10.1016/j.biologicals.2006.02.007 View Article Google Scholar Lu H, Zhao WM, Zheng Y, Wang H, Qi M, Yu XP: Analysis of synonymous codon usage bias in Chlamydia. [virologyj.com]

The results from this phase 1 clinical trial show great promise, but there is still a long way to go before the treatment receives approval. Success in phase 1 trials do not always lead to treatments. [cnet.com]

“There doesn’t seem to be any resistance to re-treatment,” Bigner says. [sciencenews.org]

Another patient and young father, Brendan Steele, was featured in the program as a three-year survivor after receiving the treatment in 2013. [dukehealth.org]

Higher doses of the poliovirus therapy treatment were associated with more inflammation to the brain. [abcnews.go.com]

The first poliovirus patient, Stephanie Lipscomb, received the treatment in 2012 and has now graduated from college and is working as an oncology nurse. [today.duke.edu]

Intratumoral infusion of PVSRIPO is showing promise in the therapy of recurrent WHO grade IV malignant glioma (glioblastoma), a notoriously treatment-refractory cancer with dismal prognosis. [ncbi.nlm.nih.gov]

Unfortunately, it has a poor prognosis, with most patients dying about 14 months after it’s diagnosed. [abcnews.go.com]

“This is a devastating disease where the prognosis and outcome for patients is very poor, so for us to see long-term survivors with this new treatment is real and very encouraging,” said Dr. [scientificamerican.com]

Poliovirus is the etiological agent of poliomyelitis. [ncbi.nlm.nih.gov]

Poliovirus is the etiologic agent of the paralytic disease known as poliomyelitis. It’s also the virus I’ve worked on for most of my career. [virology.ws]

Authors’ Affiliations (1) State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou,Gansu, 730046, China References Grantham R, Gautier C, Gouy M, Mercier R, Pave A [virologyj.com]

However, the Biysk outbreak completely blurred the borderline between Sabin-like viruses and VDPVs in epidemiological terms. [ncbi.nlm.nih.gov]

Starting in 2015, injectable trivalent inactivated poliovirus vaccine (IPV) has been introduced as a part of routine immunization program in place of oral polio vaccine (OPV). [9] Pathophysiology Poliovirus is spread by the fecal-oral route and by aerosol [emedicine.medscape.com]

This report summarizes the ongoing investigation, provides information regarding poliovirus exposure risks and prevention measures in the United States, and offers recommendations to state health departments and clinicians. [ncbi.nlm.nih.gov]

Centers for Disease Control and Prevention. [pediatrics.aappublications.org]

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