Molecular serotyping conducted at PHO laboratory should identify poliovirus if present. [publichealthontario.ca]

Environmental surveillance (ES) can detect circulating polioviruses from sewage without relying on clinical presentation. [ncbi.nlm.nih.gov]

Polio clinical and laboratory surveillance Regulation 2(1)(b) of the Health Protection (Notification) Regulations 2010 place a duty on registered medical practitioners (RMPs) to report any suspected infections that present or could present significant [gov.uk]

Diagnostic workup and treatment were performed in Italy. Poliovirus replicated in the gut for 7 months. The 5' non coding region (NCR), VP1, VP3 capsid proteins and the 3D polymerase genomic regions of sequential isolates were sequenced. [ncbi.nlm.nih.gov]

• Chlamydia

  Analysis of synonymous codon usage bias in Chlamydia. Acta Biochim Biophys Sin (Shanghai) 2005; 37 :1–10. doi: 10.1093/abbs/37.1.1. [ PubMed ] [ CrossRef ] [ Google Scholar ] Wright F. The 'effective number of codons' used in a gene. [ncbi.nlm.nih.gov]

  Biologicals 2006, 34: 103-108. 10.1016/j.biologicals.2006.02.007 View Article Google Scholar Lu H, Zhao WM, Zheng Y, Wang H, Qi M, Yu XP: Analysis of synonymous codon usage bias in Chlamydia. [doi.org]

The experimental treatment seems to have extended survival in a small group of patients with glioblastoma who faced a grim prognosis because standard treatments had failed, Duke University researchers say. [npr.org]

The results from this phase 1 clinical trial show great promise, but there is still a long way to go before the treatment receives approval. Success in phase 1 trials do not always lead to treatments. [cnet.com]

Another patient and young father, Brendan Steele, was featured in the program as a three-year survivor after receiving the treatment in 2013. [dukehealth.org]

The study tested the modified poliovirus on 61 patients whose tumors had recurred after initial treatments. Median survival was about a year, roughly the same as for a small group of similar patients given other treatments at Duke. [tampabay.com]

“There doesn’t seem to be any resistance to re-treatment,” Bigner says. [sciencenews.org]

Intratumoral infusion of PVSRIPO is showing promise in the therapy of recurrent WHO grade IV malignant glioma (glioblastoma), a notoriously treatment-refractory cancer with dismal prognosis. [ncbi.nlm.nih.gov]

Unfortunately, it has a poor prognosis, with most patients dying about 14 months after it’s diagnosed. [abcnews.go.com]

The experimental treatment seems to have extended survival in a small group of patients with glioblastoma who faced a grim prognosis because standard treatments had failed, Duke University researchers say. [npr.org]

Poliovirus is the etiological agent of poliomyelitis. [ncbi.nlm.nih.gov]

Poliovirus is the etiologic agent of the paralytic disease known as poliomyelitis. It’s also the virus I’ve worked on for most of my career. [virology.ws]

Etiology Acute poliomyelitis is caused by small RNA viruses of the Enterovirus genus of the Picornaviridae family. [emedicine.medscape.com]

Poliovirus (PV: family Picornaviridae, genus Enterovirus ) is the etiologic agent of poliomyelitis, a human disease of the central nervous system. [pnas.org]

PAHO/WHO Epidemiological alert: detection of vaccine-derived poliovirus type 2 (VDPV2) in the United States: implications for the region of the Americas—21 July 2022. 4. [thelancet.com]

However, the Biysk outbreak completely blurred the borderline between Sabin-like viruses and VDPVs in epidemiological terms. [ncbi.nlm.nih.gov]

III, Madrid, Spain 5 Coordinating Centre for Health Alerts and Emergencies (CCAES), Directorate General of Public Health, Ministry of Health, Madrid, Spain 6 National Centre of Epidemiology, Carlos III Health Institute, Madrid, Spain 7 Research Group [eurosurveillance.org]

Starting in 2015, injectable trivalent inactivated poliovirus vaccine (IPV) has been introduced as a part of routine immunization program in place of oral polio vaccine (OPV). [9] Pathophysiology Poliovirus is spread by the fecal-oral route and by aerosol [emedicine.medscape.com]

People need to be protected against all three types of the virus in order to prevent polio disease and the polio vaccination is the best protection. [cdc.gov]

There is no cure for polio, but it is preventable through safe and effective vaccination. The vaccine used to prevent polio in the U.S. does not cause polio. [dhs.wisconsin.gov]

There is no cure for polio; it can only be prevented by immunization. The polio vaccine, given multiple times, can protect a child for life. [who.int]

Source: Centers for Disease Control and Prevention [jamanetwork.com]

Prevention of poliomyelitis: recommendations for use of only inactivated poliovirus vaccine for routine immunization. Pediatrics. 1999 ; 104 ( 6 ): 1404 – 1406 2. ↵ Centers for Disease Control and Prevention. [pediatrics.aappublications.org]