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Polyclonal Hypergammaglobulinemia


Presentation

  • Herein, we report two unusual cases of VL that presented with several characteristics of autoimmune hepatitis (AIH).[ncbi.nlm.nih.gov]
Generalized Lymphadenopathy
  • A description is given of two patients with peculiar multiple skin eruptions, asymptomatic generalized lymphadenopathy, and polyclonal hypergammaglobulinemia.[ncbi.nlm.nih.gov]
  • lymphadenopathy with a mixed cellular infiltrate of lymphocytes, immunoblasts, and plasma cells that alters or… … Medical dictionary Cryoglobulinemia — Classification and external resources ICD 10 D89.1 ICD 9 273.2 … Wikipedia[medicine.academic.ru]
  • A syndrome of peculiar multiple skin eruptions, generalized lymphadenopathy, and polyclonal hypergammaglobulinemia. ( 3777978 ) Watanabe S....Mori S. 1986 21 Helper T-cell lymphoma with marked plasmacytosis and polyclonal hypergammaglobulinemia.[malacards.org]
  • Results The main symptoms of AITL had fever,skin rash,general lymphadenopathy, hepatosplenomegaly, anemia and polyclonal hypergammaglobulinemia .[dict.cnki.net]
Melena
  • A 55-year-old man with a chief complaint of melena had diffusely infiltrated lymphoma from the rectum to the sigmoid colon and polyclonal hypergammaglobulinemia.[ncbi.nlm.nih.gov]
Night Sweats
  • sweats, and weight loss; generalized lymphadenopathy with a mixed cellular infiltrate of lymphocytes, immunoblasts, and plasma cells that alters or… … Medical dictionary Cryoglobulinemia — Classification and external resources ICD 10 D89.1 ICD 9 273.2[medicine.academic.ru]
Meningism
  • […] purpura 2016 2017 2018 2019 Billable/Specific Code Applicable To Purpura NOS Purpura simplex Senile purpura hypergammaglobulinemic D89.0 (benign) (Waldenström) Waldenström hypergammaglobulinemia D89.0 ICD-10-CM Codes Adjacent To D89.0 D86.81 Sarcoid meningitis[icd10data.com]

Workup

  • And such a workup at this time may not be helpful. Also, a polyclonal gammopathy is not necessarily permanent.[aaaai.org]
  • -I have had the million dollar workup. Been hospitalized twice, had lumbar puncture, 3 brain MRI's, EMG, EEG, full body CT scan. -Anyone knows any science? Protein electrophoresis shows polyclonal gammopathy, IgM kappa and lamda increased.[mdjunction.com]
  • He was scheduled for TMJ arthroplasties but preoperative workup revealed a lytic lesion in his clavicle and marked elevation of Westergren sedimentation rate (ESR). He was referred to Rheumatology Clinic for further evaluation.[hopkinsarthritis.org]
Cytopenia
  • Neither patient had a history of fever, only generalized symptoms accompanied by polyclonal hypergammaglobulinemia, cytopenias, signs of portal hypertension, elevated transaminases, and high titers of antinuclear and smooth-muscle autoantibodies (SMA)[ncbi.nlm.nih.gov]
Liver Biopsy
  • A clinical diagnosis of AIH was considered, but a bone marrow biopsy was performed before a liver biopsy to exclude a primary bone marrow disease. The biopsy led to the diagnosis of VL.[ncbi.nlm.nih.gov]

Treatment

  • Treatment with amphotericin in the first case and pentamidine in the second (because of a severe reaction to amphotericin) was effective.[ncbi.nlm.nih.gov]
  • Children with PHG and AML were more likely to be in CR after first induction treatment (OR 6.25, p 0.021), independent of sex, age at diagnosis, white blood cell count, percentage of blasts in the bone marrow, FAB phenotype, and treatment protocol.[link.springer.com]

Prognosis

  • The prognosis of SP reportedly has been good. A 59-year-old Japanese man was treated for multiple cutaneous lesions of his trunk as well as polyclonal hypergammaglobulinemia.[ncbi.nlm.nih.gov]
  • Its prognosis is variable in different patients. The discrepancy of prognosis between children and adults is worthy of study, and individualized therapy of AITL must be adopted. 目的 通过对 6例儿童血管免疫母细胞性T细胞淋巴瘤 (AITL)临床表现的分析 ,为儿童AITL的诊断和治疗提供依据。[dict.cnki.net]
  • Diagnosis, prognosis, and standard treatment of multiple myeloma. Hematol Oncol Clin North Am. 1997;11:111–31. 13. Kyle RA, Therneau TM, Rajkumar SV, Offord JR, Larson DR, Plevak MF, et al.[aafp.org]
  • In extreme cases, the increased concentration of IgM in the blood can lead to heart failure. symptoms,prognosis and treatments in WM. doc c)Lymphomas,Leukemias(10%) d) Monoclonal gammopathy of undetermined significance 10% INTRODUCTION : Monoclonal gammopathy[flipper.diff.org]
  • Diagnosis, prognosis and standard treatment of multiple myeloma. Hematol Oncol Clin North Am. 1997;11:111–31. Kyle R , Garton J. Laboratory monitoring of myeloma proteins. Seminars in Oncology 1986;13(3):310-17. Keren, DF. Multiple Myeloma.[bpac.org.nz]

Etiology

  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • . * Comprehensive current coverage of basic models of etiology and pathogenesis * Complete catalog of autoantibodies produced * Includes an outstanding review of imaging techniques for the diagnosis of lupus and its complications for each organ system[books.google.ro]
  • Página 330 - Intestinal infections in patients with the acquired immunodeficiency syndrome (AIDS): etiology and response to therapy. ‎[books.google.es]
  • It is supposed that overproduction of IL-6 by unknown etiology in IPL induces proliferation of mesangial cells and infiltration of plasma cells into the renal interstitium, and these processes may be augmented by paracrine or autocrine of IL-6 by primed[academic.oup.com]

Pathophysiology

  • Polyclonal hypergammaglobulinemia polyclonal gammopathy Pathophysiology of polyclonal gammopathy Polyclonal hypergammaglobulinemia is usually due to an underlying infectious, inflammatory or neoplastic disorder such as a carcinoma.[barnardhealth.us]
  • A brief review of the history and various manifestations of sarcoidosis including the pathophysiology of hypercalcaemia in sarcoidosis are presented as well as of polyclonal gammopathy.[casereports.bmj.com]
  • Página 302 - Groszmann RJ, Atterbury CE: The pathophysiology of portal hypertension: a basis for classification. Semin Liver Dis 1982; 2:177. ‎[books.google.es]
  • Useful For Suggests clinical disorders or settings where the test may be helpful Detecting or monitoring of monoclonal gammopathies and immune deficiencies Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they[mayomedicallaboratories.com]

Prevention

  • - 0% Emergent - ED Care Needed - Preventable/Avoidable - 0% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary diagnosis[medicbind.com]
  • This case may give suggestions about diagnosing and preventing the progression of complications from this disease entity.[ncbi.nlm.nih.gov]
  • A comparison of filtered leukocyte-reduced and cytomegalovirus (CMV) seronegative blood products for the prevention of transfusion-associated CMV infection after marrow transplant. Blood 1995; 86:3598-3603. ‎[books.google.ro]

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