We present a patient with polycystic disease of the liver who developed an aneurysm arising from the right hepatic artery presenting with surgical obstructive jaundice. [ncbi.nlm.nih.gov]

• Anorexia

  Despite preserved liver function, the patient's clinical condition was poor; she experienced dyspnea, advanced anorexia, abdominal pain, and severe ascites. [ncbi.nlm.nih.gov]

  Cystadenoma: This rare disorder sometimes causes pain or anorexia and is evident on ultrasonography; treatment is cyst resection. [merckmanuals.com]

  The larger cysts, especially if located on the left lobe, may compress adjacent visceral structures such as the stomach, with advanced anorexia and gastroesophageal reflux symptoms. [gastroenterologyandhepatology.net]

• Abdominal Pain

  While mild abdominal pain was observed in a few patients, it was resolved spontaneously under observation. [ncbi.nlm.nih.gov]

• Loss of Appetite

  Symptoms And Signs Of Polycystic Liver Disease (PLD) Non-Specific Symptoms of Polycystic Liver Disease (PLD) Loss of weight. Loss of appetite. Fatigue and weakness. [epainassist.com]

• Headache

  Polycystic kidney disease care at Mayo Clinic Symptoms Polycystic kidney disease symptoms can include: High blood pressure Back or side pain Headache A feeling of fullness in your abdomen Increased size of your abdomen due to enlarged kidneys Blood in [mayoclinic.org]

  […] screening [ 51 ] -positive family history of (ruptured) ICA or stroke -previously ruptured ICA Surveillance/rescreening after negative results in patients with a positive family history: 5–10 years (high-to low-risk) [ 13, 81 ] -warning symptoms: unusual headaches [ojrd.biomedcentral.com]

She refused further workup including liver biopsy. Discussion Polycystic liver disease occurs either in isolation or as part of ADPKD or uncommonly adult dominant polycystic liver disease (ADPLD). [cureus.com]

Although various treatments for symptomatic adult polycystic liver disease have been advocated, a definitive treatment remains controversial, especially in diffuse adult polycystic liver disease. [ncbi.nlm.nih.gov]

To identify predictor factors, beyond MELD criteria that relate to the increased liver volume before development of late symptoms is essential to expeditiously treat patients with the poorest prognosis to improve their outcomes. [ncbi.nlm.nih.gov]

Prognosis Most patients with PCLD have good prognosis and do not require treatment. The documents contained in this web site are presented for information purposes only. [orpha.net]

Case report peer-reviewed Polycystic Liver Disease and Sarcoidosis: Unusual Coexisting Etiologies of Portal Hypertension Figures etc. [cureus.com]

[…] resemble corpora atretica or fibrosa of ovary TERMINOLOGY Abbreviations • Polycystic liver disease (PLD) • Autosomal dominant polycystic kidney disease (ADPKD) Definitions • Genetic disorder characterized by progressive development of multiple liver cysts ETIOLOGY [basicmedicalkey.com]

Etiology Liver cysts result from overgrowth of biliary epithelium or from dilatation of peribiliary glands. Some cases occur sporadically, but most are inherited as an autosomal dominant trait (ADPCLD). [orpha.net]

Banales J.M. 2017 18 Waitlisted Candidates With Polycystic Liver Disease are More Likely to be Transplanted Than Those With Chronic Liver Failure. ( 28296808 ) Doshi S.D....Goldberg D.S. 2017 19 Polycystic Liver Disease and Sarcoidosis: Unusual Coexisting Etiologies [malacards.org]

Areas covered: This review begins by looking at the epidemiology of PLD and its natural history. It then describes the pathophysiology and corresponding potential treatment strategies for PLD. [ncbi.nlm.nih.gov]

Summary Epidemiology The prevalence of ADPCLD is 1/100, 000. Clinical description Women are predominantly affected and have a larger number of cysts than affected males. [orpha.net]

The rate of single cysts is about 68–75 % [ 5, 6 ]. 8.2.1 Pathogenesis and Epidemiology Simple cysts contain a clear, bile-like fluid. [abdominalkey.com]

Abu-Wasel, B., et al., Pathophysiology, epidemiology, classification and treatment options for polycystic liver diseases. World J Gastroenterol, 2013. 19(35): p. 5775-86. 4. [rarediseases.org]

AIM: To provide a systemic review on the pathophysiology and management of PCLD. [ncbi.nlm.nih.gov]

Temmerman, F., et al., Systematic review: the pathophysiology and management of polycystic liver disease. Aliment Pharmacol Ther, 2011. 34(7): p. 702-13. 8. [rarediseases.org]

The sclerosing treatment was successful, thus preventing laparotomy. [ncbi.nlm.nih.gov]

The use of postoperative long-acting octreotide has the potential to reduce the growth of remaining cysts and prevent new cysts from developing, and it should be considered in the management of these patients after surgery. [jamanetwork.com]