Presentation
Rarely there is choriocarcinoma, and syncytiotrophoblast and hepatoid cells are occasionally present. [ncbi.nlm.nih.gov]
One presented with isosexual precocity, 8 while the remainder presented with abdominal pain and/or pelvic mass. [nature.com]
Entire Body System
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Precocious Puberty
A 4.5-year-old boy presented with isosexual precocious puberty and an anterior mediastinal mass. Surgical resection demonstrated a teratoma with foci of malignant mixed germ cell tumor elements of polyembryoma. [ncbi.nlm.nih.gov]
Symptoms of a polyembryoma may include an unusual bump or mass in the abdomen which can cause pain in some individuals; puberty at an unusually young age (known as precocious puberty); or irregularities in a female's menstruation. [diseaseinfosearch.org]
puberty ); or irregularities in a female's menstruation. [rarediseases.info.nih.gov]
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Hodgkin Lymphoma
Abstracts: Polyembrioma of the testis: case report following chemotherapy for non-Hodgkin's lymphoma. G Chir.2002 Mar;23(3):65-70. Testicular tumours represent 2% of all male malignancies, mostly concerning young men (20-40 years old). [diagnostichistopathology.blogspot.com]
Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2 12 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2 13 Ipilimumab [malacards.org]
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Turkish
Danish Dutch English Estonian Finnish French German Greek Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Korean Latvian Lithuanian Malagasy Norwegian Persian Polish Portuguese Romanian Russian Serbian Slovak Slovenian Spanish Swedish Thai Turkish [dictionary.sensagent.com]
The hospital is part of the largest Turkish network of the Medicana hospitals, which due to its long successful clinical activities has won the lea Diagnostics of polyembryoma ovarian Chemotherapy of polyembryoma ovarian (1 course) Surgery treatment of [bookinghealth.com]
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Vietnamese
Dutch English Estonian Finnish French German Greek Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Korean Latvian Lithuanian Malagasy Norwegian Persian Polish Portuguese Romanian Russian Serbian Slovak Slovenian Spanish Swedish Thai Turkish Vietnamese [dictionary.sensagent.com]
Respiratoric
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Pneumonia
ID Phase Drugs 1 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide 2 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia [malacards.org]
Gastrointestinal
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Abdominal Pain
Abdominal pain associated with a palpable pelvic–abdominal mass is present in approximately 85% of patients with germ cell tumors. [obgynkey.com]
[…] omentum, peritoneal bx -TAHBSO if childbearing complete -BEP x 4 cycles (unless Ia dysgerminoma or IaI immature teratoma) -RT for dysgerminoma curative 100% unilateral schiller-duval bodies AFP 80% survival - most aggressive rapid/ aggressive growth -75% abdominal [quizlet.com]
Side effects of treatment, which can be severe and include abdominal pain, bloating, fatigue, and infection, may prevent patients from completing all 6 cycles. [healthcommunities.com]
The average patient age is 22 years. 23 Most patients present with a rapidly growing abdominal mass that often causes lower abdominal pain or pressure and may simulate pregnancy. [clinicalgate.com]
One presented with isosexual precocity, 8 while the remainder presented with abdominal pain and/or pelvic mass. [nature.com]
Urogenital
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Scrotal Mass
The tumors are generally large, more so in females in whom gonadal tumors are generally larger than in the male due to the later clinical presentation of an intra-abdominal as opposed to intra-scrotal mass. [nature.com]
Workup
X-Ray
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Posterior Mediastinal Mass
Removal of a retropleural, posterior mediastinal mass with an intraspinous epidural extension was followed by prompt declines in the plasma concentrations of the tumor markers and cessation of adolescent development. [ncbi.nlm.nih.gov]
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Anterior Mediastinal Mass
A 4.5-year-old boy presented with isosexual precocious puberty and an anterior mediastinal mass. Surgical resection demonstrated a teratoma with foci of malignant mixed germ cell tumor elements of polyembryoma. [ncbi.nlm.nih.gov]
Treatment
Cost for treatment Diagnostics of polyembryoma ovarian Chemotherapy of polyembryoma ovarian (1 course) Surgery treatment of polyembryoma ovarian University Hospital Rechts der Isar Munich location_on Germany, Munich Department of Gynecology, Mammology [bookinghealth.com]
She is well, and her serum levels of AFP and hCG have not been elevated for more than 4 years after the treatment. [ncbi.nlm.nih.gov]
CLOSE Medical Disclaimer The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. [diseaseinfosearch.org]
Helps you take advantage of the latest advances in early detection and improved treatment options for gynecologic cancers, especially uterine and cervical cancers. [books.google.ro]
Prognosis
The authors of this study suggest that prognosis might vary depending on the precise make-up of each tumor. [3] Last updated: 3/20/2012 Research helps us better understand diseases and can lead to advances in diagnosis and treatment. [rarediseases.info.nih.gov]
Etiology
The Authors analyse some aspects concerning etiology, pathology and clinical approach to such rare neoplasm. [diagnostichistopathology.blogspot.com]
Mostofi, FK 1973 Proceedings: testicular tumors Epidemiologic, etiologic and pathologic features. Cancer 32 1186 1201 Google Scholar 10. Exelby, P 1980 Testicular cancer in children Cancer 45 1803 1809 Google Scholar 11. [link.springer.com]
The etiology of embryonal cancer is not known. [bigmed.info]
Etiology No factors have been associated with the aetiology of GCT, apart from an increased incidence associated with dysgenetic gonads. 5% of patients with dysgerminomas are associated with constitutional cytogenetic abnormalities involving the entirety [atlasgeneticsoncology.org]
Epidemiology
Mostofi, FK 1973 Proceedings: testicular tumors Epidemiologic, etiologic and pathologic features. Cancer 32 1186 1201 Google Scholar 10. Exelby, P 1980 Testicular cancer in children Cancer 45 1803 1809 Google Scholar 11. [link.springer.com]
The national database of the Saudi Cancer Registry (SCR) on testicular cancer over the last two decades was studied including epidemiological and histological patterns... [read.qxmd.com]
Nonepithelial cancers among adults, Epidemiology, 1992, vol. 3 (pg. 490 - 495 ) 4. Clinicopathologic review of 118 granulosa and 82 theca cells tumors, Obstet Gynecol, 1980, vol. 55 (pg. 231 - 238 ) 5. [academic.oup.com]
Well-established epidemiologic causes of GCTs are listed in Table 4.2. The average age of patients at presentation significantly correlates with the pathologic type of GCTs (Table 4.3 ). [abdominalkey.com]
Epidemiology GCT predominantly affect young women, but they do sometimes occur in infants and older women. GCT account for over 60% of ovarian neoplasms in children and adolescents, one-third of which are malignant. [atlasgeneticsoncology.org]
Pathophysiology
The book emphasizes the correlation between clinical and pathologic features of female genital tract disease by examining the pathophysiology of individual organ systems. [books.google.ro]
Mutism and pseudobulbar symptoms after resection of posterior fossa tumors in children: incidence and pathophysiology. Neurosurgery 37 (5): 885-93, 1995. [cancerinfo.tri-kobe.org]
Prevention
Those at very high risk may have their ovaries removed as a preventive measure. If caught and treated in an early stage, ovarian cancer is often curable. Treatment usually includes some combination of surgery, radiation therapy, and chemotherapy. [howlingpixel.com]
[…] cyclophosphamide 2 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin 3 Itraconazole Compared With Fluconazole to Prevent [malacards.org]
The research results in Erlangen set new standards in the prevention, diagnosis and tre Diagnostics of polyembryoma ovarian Chemotherapy of polyembryoma ovarian (1 course) Surgery treatment of polyembryoma ovarian University Hospital Halle (Saale) location_on [bookinghealth.com]
Side effects of treatment, which can be severe and include abdominal pain, bloating, fatigue, and infection, may prevent patients from completing all 6 cycles. [healthcommunities.com]