A 4.5-year-old boy presented with isosexual precocious puberty and an anterior mediastinal mass. Surgical resection demonstrated a teratoma with foci of malignant mixed germ cell tumor elements of polyembryoma. [ncbi.nlm.nih.gov]

Symptoms of a polyembryoma may include an unusual bump or mass in the abdomen which can cause pain in some individuals; puberty at an unusually young age (known as precocious puberty); or irregularities in a female's menstruation. [diseaseinfosearch.org]

puberty ); or irregularities in a female's menstruation. [rarediseases.info.nih.gov]

Abstracts: Polyembrioma of the testis: case report following chemotherapy for non-Hodgkin's lymphoma. G Chir.2002 Mar;23(3):65-70. Testicular tumours represent 2% of all male malignancies, mostly concerning young men (20-40 years old). [diagnostichistopathology.blogspot.com]

Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2 12 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2 13 Ipilimumab [malacards.org]

Danish Dutch English Estonian Finnish French German Greek Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Korean Latvian Lithuanian Malagasy Norwegian Persian Polish Portuguese Romanian Russian Serbian Slovak Slovenian Spanish Swedish Thai Turkish [dictionary.sensagent.com]

The hospital is part of the largest Turkish network of the Medicana hospitals, which due to its long successful clinical activities has won the lea Diagnostics of polyembryoma ovarian Chemotherapy of polyembryoma ovarian (1 course) Surgery treatment of [bookinghealth.com]

Dutch English Estonian Finnish French German Greek Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Korean Latvian Lithuanian Malagasy Norwegian Persian Polish Portuguese Romanian Russian Serbian Slovak Slovenian Spanish Swedish Thai Turkish Vietnamese [dictionary.sensagent.com]

ID Phase Drugs 1 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide 2 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia [malacards.org]

Abdominal pain associated with a palpable pelvic–abdominal mass is present in approximately 85% of patients with germ cell tumors. [obgynkey.com]

[…] omentum, peritoneal bx -TAHBSO if childbearing complete -BEP x 4 cycles (unless Ia dysgerminoma or IaI immature teratoma) -RT for dysgerminoma curative 100% unilateral schiller-duval bodies AFP 80% survival - most aggressive rapid/ aggressive growth -75% abdominal [quizlet.com]

Side effects of treatment, which can be severe and include abdominal pain, bloating, fatigue, and infection, may prevent patients from completing all 6 cycles. [healthcommunities.com]

The average patient age is 22 years. 23 Most patients present with a rapidly growing abdominal mass that often causes lower abdominal pain or pressure and may simulate pregnancy. [clinicalgate.com]

One presented with isosexual precocity, 8 while the remainder presented with abdominal pain and/or pelvic mass. [nature.com]

The tumors are generally large, more so in females in whom gonadal tumors are generally larger than in the male due to the later clinical presentation of an intra-abdominal as opposed to intra-scrotal mass. [nature.com]

Removal of a retropleural, posterior mediastinal mass with an intraspinous epidural extension was followed by prompt declines in the plasma concentrations of the tumor markers and cessation of adolescent development. [ncbi.nlm.nih.gov]

A 4.5-year-old boy presented with isosexual precocious puberty and an anterior mediastinal mass. Surgical resection demonstrated a teratoma with foci of malignant mixed germ cell tumor elements of polyembryoma. [ncbi.nlm.nih.gov]