Presentation
Readers are guided through the maze that too often lies between the presenting skin complaint and its final diagnosis and treatment. [books.google.com]
PowerPoint Presentation: Photosynthesis Skin Damage Mood elevation Kills pathogens Sight Warmth Skin Cancer Cataracts Vitamin D PowerPoint Presentation: Stratosphere UVC UVA UV B Stratosphere 10-50km Troposphere 0-10km PowerPoint Presentation: Atmosphere [authorstream.com]
Acute Polymorphous Light Eruption Presented by: David Elpern MD, Williamstown, MA, USA on July 17, 2001 History : M.R. is a 74-year-old woman who presented with a four day history of a very pruritic eruption on the anterior thighs. [vgrd.org]
A 35-year-old female presented with history of relapsing facial rash and fever since 3 years. The facial lesions progressed through small papules or vesicles before healing with atrophic scars. [academic.oup.com]
The infiltrate was of T cell lineage, confirmed by immunoperoxidase staining, with diffuse expression of CD3 (fig 2B); scattered CD8 positive lymphocytes were present (fig 2C). [bjo.bmj.com]
Entire Body System
- Weakness
This is due not only to the fair skin of babies, but also to their weak immunity. To provoke a solar dermatitis various infringements in work of an organism can. [acikgunluk.net]
Shave biopsy shows epidermal spongiosis, vesiculation and necrosis accompanied by an atypical lymphoid infiltrate and scattered neutrophils and eosinophils Lymphocytic infiltrate is CD3+, TIA+, subset weak CD4+, subset CD30+ and negative for CD8 and CD56 [pathologyoutlines.com]
People with large affected areas sometimes have headaches and wheezing and feel dizzy, weak, and nauseated. Over 100 substances, swallowed or applied to the skin, are known to cause sun-induced reactions on the skin. [msdmanuals.com]
There is a wide differential diagnosis for the clinical symptoms of cutaneous manifestations and muscle weakness in DM patients. [link.springer.com]
- Fatigue
Immune Deficiency Syndrome (CFIDS) Chronic Fatigue Syndrome Chronic Hepatitis Chronic Obstructive Pulmonary Disease Chronic Pancreatitis Chronic Pelvic Pain Syndrome (in men) Chronic Prostatitis Cigarette Addiction Cigarette Smokers, Nutrition Cirrhosis [therapy.epnet.com]
It is most commonly used in combination with chemotherapy The radiation may be administered by a machine placed outside the body, or by placing a radioactive material inside the body The side effects of radiation therapy include nausea, vomiting, fatigue [dovemed.com]
In addition, the patient may suffer from general weakness and fatigue if he has complicated sunny dermatitis. The photo below shows how this allergy might look like. [acikgunluk.net]
The patient reported mild malaise and lethargy during vesicular phase of illness, but no other symptoms like fever or chills, burning in eyes, arthralgia, weight loss, easy fatiguability, bruising tendency, abdominal discomfort, or features suggestive [idoj.in]
[…] varicella, scarlet fever, cellulitis, fifth disease, folliculitis Unexplained weight changes, menstrual irregularity, heat/cold intolerance Thyroid disease with secondary urticaria or xerosis Unexplained weight loss, night sweats, unexplained fevers, fatigue [aafp.org]
- Weight Gain
Steroid tablets and injections can also be given but side effects include weight gain, bone thinning and immune suppression, so these are not long-term options. The best way to avoid it is by using a UVA filter sunscreen and staying out of the sun. [dailymail.co.uk]
Treatment – Prescription steroid ointments – Steroid tablets and injections can also be given but side effects include weight gain, bone thinning and immune suppression, so these are not long-term options. [skinmagazine.co.uk]
gain and multiple gestation 6 Excellent maternal and fetal prognoses No cutaneous involvement in newborn Does not tend to recur in subsequent pregnancies Table 4. [aafp.org]
- Falling
A natural fall in oestrogens may account for the tendency to remit after the menopause. Lehmann P, Schwarz T ; Photodermatoses: diagnosis and treatment. Dtsch Arztebl Int. 2011 Mar108(9):135-41. Epub 2011 Mar 4. [patient.info]
Symptoms An individual may fall anywhere between mild and severe on the photosensitivity spectrum. This means that they may need very little time in the sun to develop a rash, or a longer period of time than normal. [sunsaferx.com]
- Asymptomatic
[…] frequently found on the nose, cheeks, ears, dorsum of the hand, and arms (places that are most exposed to light). [3] Causes [ edit ] Hydroa vacciniforme is commonly associated with reactivation of a latent Epstein-Barr virus (EBV]] formerly acquired by an asymptomatic [en.wikipedia.org]
Each year, hundreds of bites are reported, responsible for various events ranging from asymptomatic bite to death, through cardiac or neurologic, systemic involvement [ 1 ]. [omicsonline.org]
Gastrointestinal
- Nausea
The rash usually appears on sun-exposed portions of the neck, upper chest, arms and lower legs, and may be accompanied by one to two hours of chills, headache and nausea. [mysunallergy.com]
[…] like eczema rashes There may be dry and scaly abnormal areas on skin In chronic cases, the skin may become thick and elicit scarring Hives may also form Skin with photodermatitis blisters/rashes may elicit burning sensations Fever and chills, headache, nausea [healthmomma.com]
Chills, headache, fever, and nausea in some cases. Long term effects include thickening and scarring of the skin and an increased risk of skin cancer, if the cause is genetic. [medigoo.com]
Itchy, scaly, blisters, or raised areas Lesions that appears like an eczema Hyperpigmented discoloration of the skin Outbreaks in areas of skin which are overexposed to UV light Pain, erythema, and swelling in affected areas Chills, headache, fever, and nausea [medicalfoxx.com]
Under such circumstances, removing all the affected lymph nodes would be extremely difficult Supportive treatment: Steroids, blood transfusions, anti-nausea medications, and antibiotics, may be used as supportive therapy. [dovemed.com]
- Vomiting
It is most commonly used in combination with chemotherapy The radiation may be administered by a machine placed outside the body, or by placing a radioactive material inside the body The side effects of radiation therapy include nausea, vomiting, fatigue [dovemed.com]
If vast areas of the body are affected, the loss of fluid into the skin could lead to light-headedness, headache, nausea, and vomiting. [1] [12] Extremely rarely, patients have been reported to experience an increase in heart rate that can cause a stroke [en.wikipedia.org]
Skin
- Eruptions
The 4 most common types of sun allergies are: Polymorphous light eruption (PMLE), also called Polymorphic Light Eruption (PLE). Actinic prurigo (hereditary PMLE) Photoallergic eruption Solar urticaria Polymorphous light eruption (PMLE). [mysunallergy.com]
[…] light eruption EnglishMedDRA 10036087 L0569654no S0716203 N Polymorphic light eruption English(RCD) Read Codes X504x L0569654no S0716203 N Polymorphic light eruption EnglishMedDRA 10036087 L0569654no S0716203 N Polymorphic light eruption EnglishSNOMEDCT_US [doctor.am]
[…] light, Photoallergic dermatitis, delayed, PLE - Polymorphic light eruption, PLE - Polymorphic light eruptn, Polymorphic light eruption, Polymorphic photodermatitis, POLYMORPHOUS LIGHT ERUPTION, Polymorphous light eruption, NOS [dermis.net]
Polymorphous light eruption and beningn summer light eruption in Italy. Photodermatol Photoimmunol Photomed. 2011; 27: 35-39. Scheinfeld N Shirin S Del Rosario R. Polymorphous Light Eruption. Medscape. 2018. Epstein J. Polymorphous Light Eruption. [medigraphic.com]
Polymorphous light eruption on the thighs and hand. Courtesy of DermNet New Zealand (http://www.dermnetnz.org/assets/Uploads/reactions/pmle2.jpg). Polymorphous light eruption on the arm. [emedicine.medscape.com]
- Photosensitivity
Zealand Dermatological Society The most common photosensitivity is to UVA. [vitamindwiki.com]
Classifications of photosensitivity: Exogenous photodermatoses: This is when a photosensitive reaction is caused by an outside photosensitizer. [sunsaferx.com]
Photosensitivity Who gets photosensitivity ? Photosensitivity occurs in males and females of all races and at all ages. Different types of photosensitivity may be prevalent at different times of life. Genetic and environmental factors are involved. [dermnetnz.org]
Offering broad coverage of the basic, clinical and curative aspects of photomedicine, this reference reflects the recent expansion of knowledge on the effects of light on normal skin as well as photosensitivity disorders and the use of light in treating [books.google.com]
Figure: 1 Photosensitive distribution The red areas show those parts of the face most affected by photo-sensitive dermatoses Figure: 2 Drug-induced photosensitivity Note the relative sparing of photo-protected areas Figure: 3 Airborne contact dermatitis [pcds.org.uk]
- Skin Lesion
photosensitizing protoporphyrin accumulates in red blood cells, plasma, skin and liver; histopathology of the skin lesions differs, demonstrating intense, mainly neutrophilic infiltrate in the dermis in acute lesions and varying amounts of an amorphous [clinicaladvisor.com]
Once you have narrowed down the diagnosis, cross-references then guide you to more detailed descriptions, and another 700 photographs, covering: · common infections · inflammatory rashes · non-inflammatory conditions · skin lesions Every section provides [books.google.com]
Although the skin lesions are not exclusively limited to sun-exposed areas and do not only appear after sun exposure, as do HV skin lesions, there is a seasonal increased occurrence during the summer. [bloodjournal.org]
The patient was treated with Chinese herbal drugs and her skin lesions waxed and waned. [thedoctorsdoctor.com]
Abstract Hydroa Vacciniforme (HV) is a rare, acquired and chronic paediatric disorder that is characterized by photosensitivity and recurrent crops of skin lesions on sun-exposed skin, such as the face, ears and hands that heal with vacciniforme scarring [scopemed.org]
- Papule
The facial lesions progressed through small papules or vesicles before healing with atrophic scars. She had responded to topical corticosteroid therapy previously. [academic.oup.com]
Abstract A case of hydroa vacciniforme that started at the age of 2 years with erythema and papule and healed with scar formation was followed up from the age of 13 to 21 years. [jstage.jst.go.jp]
[…] excretion of porphyrins is abnormally large; in urine there is usually excess uro porphyrin whereas in feces there is excess copro porphyrin and proto porphyrin. 1 For many years it has been noted that a large variety of cutaneous lesions (macules, papules [nejm.org]
These are smooth flat-topped papules, often slightly brown in colour, and commonest on the face (Fig. 2) and dorsal aspects of the hands. [studfiles.net]
These turn into dimpled, pit-like papules with black scabs ( necrosis ) on a red and inflamed base Lesions heal to form pale depressed scars The rash usually first appears in spring with recurrences throughout the summer months. [dermnetnz.org]
- Erythema
Minimum erythema dose (MED) to ultraviolet (UV) A and B was normal but MED to monochromatic light was slightly lowered in the range between 300 and 370nm. [jstage.jst.go.jp]
The minimal erythema dose was 10 seconds. [1pdf.net]
[…] hydroa vaccinifor´me a vesicular and bullous eruption, which may be preceded by pruritus and burning sensation, having a tendency to recur each summer during childhood on sun-exposed areas of the skin. hy·dro·a vac·ci·ni·for·'me a recurrent eruption of erythema [medical-dictionary.thefreedictionary.com]
In phototoxicity, light-absorbing compounds directly generate free radicals and inflammatory mediators, causing tissue damage manifesting as pain and erythema (like sunburn). [msdmanuals.com]
Neurologic
- Dizziness
Rarely, if large areas are involved, syncope, dizziness, wheezing, and other systemic symptoms may develop. [msdmanuals.com]
Sedation, dizziness, peripheral neuropathy in all age groups and teratogenicity in women of child-bearing age argues against its use. Cyclosporin A in a dose of 2 to 3mg/kg/day was effective in a patient with adult onset of HV. [clinicaladvisor.com]
- Asthenia
The patients usually have systemic symptoms including fever, weight loss, and asthenia. [bloodjournal.org]
- Lethargy
The patient reported mild malaise and lethargy during vesicular phase of illness, but no other symptoms like fever or chills, burning in eyes, arthralgia, weight loss, easy fatiguability, bruising tendency, abdominal discomfort, or features suggestive [idoj.in]
Treatment
Readers are guided through the maze that too often lies between the presenting skin complaint and its final diagnosis and treatment. [books.google.com]
treatment and/or systemic treatment, when the whole body is affected In some children, the condition progresses rapidly, while in others the progress is slower. [dovemed.com]
Woodburne A.R., Philpott O.S., Philpott J.A. (1964) Quinacrine (Atabrine) in treatment of solar dermatoses. [link.springer.com]
Treatment – Berloque dermatitis is a permanent skin condition so the only treatments are ones that removed the surface or the skin. [skinmagazine.co.uk]
Prognosis
The prognosis of the condition is poor; only 1 in 3 survive after 2 years of diagnosis The prognosis depends upon a set of several factors, which include: Stage of tumor: With lower-stage tumors, when the tumor is confined to site of origin, the prognosis [dovemed.com]
The aggressive types of extra ocular sebaceous neoplasm are reported with lymph node and visceral metastasis associated with poor prognosis. [ingentaconnect.com]
Prognosis - Hydroa vacciniforme Not supplied. Treatment - Hydroa vacciniforme Not supplied. Resources - Hydroa vacciniforme Not supplied. [checkorphan.org]
[…] in-Chief: Alberto Plate [2] Synonyms and Keywords: Hydroa-like CTCL, HVLL Overview Hydroa vacciniforme-like lymphoma (HVLL) is an EBV -positive peripheral T-cell lymphoma ( non-Hodgkin's lymphoma ), that affects primarily pediatric patients and has a bad prognosis [wikidoc.org]
Etiology
Table 1 includes historical findings that suggest etiologies for pruritus. Enlarge Print Table 1. [aafp.org]
The etiology is unknown. [skincareguide.ca]
The etiology of the condition is still unknown; there is theory of an abnormal sensitivity to the UVA (Ultraviolet rays type A) radiation in a range of 320 to 390 nm of wavelength. [oxyhives.org]
[…] and Mexico Epidemiology Mainly children and adolescents from Asia, or Native Americans from Central and South America, and Mexico Rare in adults Sites Sun exposed skin, particularly the face (cheeks, nose, lower lip) but also ears and dorsum of hands Etiology [pathologyoutlines.com]
Etiology is unclear but may involve endogenous skin constituents functioning as photoallergens, leading to mast cell degranulation as in other types of urticaria. [msdmanuals.com]
Epidemiology
Journal Journal ID (nlm-ta): Pan Afr Med J Journal ID (iso-abbrev): Pan Afr Med J Journal ID (publisher-id): PAMJ Title: The Pan African Medical Journal Publisher: The African Field Epidemiology Network ISSN (Electronic): 1937-8688 Publication date (Electronic [scienceopen.com]
Papulovesicular eruption resulting in ulceration and scarring Wasting Diagnostic Exams Flow cytometry Immunohistochemistry Immunophenotyping Progression and Transformation Recurrent skin lesion s for 10-15 years before progression to system ic involvement Epidemiology [seer.cancer.gov]
Occurs in children and associated with sun sensitivity ( WHO 2008 ) Increased frequency in Asians and Native Americans from Central and South America, and Mexico Epidemiology Mainly children and adolescents from Asia, or Native Americans from Central [pathologyoutlines.com]
Pipelzadeh MH, Jalali A, Taraz M, Pourabbas R, Zaremirakabadi A (2007) An epidemiological and a clinical study on scorpionism by the Iranian scorpion Hemiscorpius lepturus. Toxicon 50: 984-992. [omicsonline.org]
[…] type Mycosis fungoides Precursor T-cell lymphoblastic lymphoma Peripheral T-cell lymphoma, not otherwise characterized Primary cutaneous anaplastic large cell lymphoma Subcutaneous panniculitis-like T-cell lymphoma Lupus [10] Herpes simplex [11] [1] Epidemiology [wikidoc.org]
Pathophysiology
Polymorphic lucite (PL) is a frequent photodermatosis, but its pathophysiologic mechanism is still poorly elucidated. [scienceopen.com]
Supporting Research at http://umm.edu/health/medical/altmed/condition/photodermatitis Skin Disorders, Photodermatitis -> Overview, Definition, Etiology Risk Factors, Signs and Symptom,s Differential Diagnosis, Diagnosis, Physical Examination, Pathology/Pathophysiology [medicalfoxx.com]
The pathophysiology differs in these disorders but photoprotection is the most integral part of their management. [ijdvl.com]
Part 1: pathophysiology and technical aspects of photobiologic studies. Actas Dermosifiliogr 105: 112-121. [omicsonline.org]
Historical Perspective HVLL reports date back to 1986; [5] however, it is not until 2008 that the WHO recognized HVLL as a separate entity from Hydroa vacciniforme and classified it under "EBV positive T-cell lymphoproliferative disorders of childhood". [2] Pathophysiology [wikidoc.org]
Prevention
Cachexia Calcium Oxalate Stones Cancer Prevention (Reducing the Risk) Cancer Treatment Support Candida Candida/Yeast Hypersensitivity Syndrome Canker Sores Car Sickness Cardiac Arrhythmia Cardiac Autonomic Neuropathy, Diabetic Cardiomyopathy Caries, Prevention [therapy.epnet.com]
Treatment – A cool bath – Calming and anti-itching bath soaks – Aloe vera gel – Calamine lotion Prevention – Loose cotton clothing – Cool shower immediately after excessive sweating – A night fan for cool air circulation [skinmagazine.co.uk]
How to Prevent Photosensitivity Basic preventive measures People who are photosensitive need to take active measures toward preventing sun exposure to keep their skin healthy. [sunsaferx.com]
The goal of eczema treatments is to relieve the symptoms, prevent itching and infections and treat the allergy. [drhealthclinic.com]
Prevention includes proper sunscreen and wearing hat and clothes that cover the entire body. It is best if people with this condition avoid excessive exposure to sun particularly between 11 AM to 4 PM. [ic.steadyhealth.com]