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Polymorphic Photodermatitis


Presentation

  • Readers are guided through the maze that too often lies between the presenting skin complaint and its final diagnosis and treatment.[books.google.com]
  • Acute Polymorphous Light Eruption Presented by: David Elpern MD, Williamstown, MA, USA on July 17, 2001 History : M.R. is a 74-year-old woman who presented with a four day history of a very pruritic eruption on the anterior thighs.[vgrd.org]
  • PowerPoint Presentation: Photosynthesis Skin Damage Mood elevation Kills pathogens Sight Warmth Skin Cancer Cataracts Vitamin D PowerPoint Presentation: Stratosphere UVC UVA UV B Stratosphere 10-50km Troposphere 0-10km PowerPoint Presentation: Atmosphere[authorstream.com]
  • A 35-year-old female presented with history of relapsing facial rash and fever since 3 years. The facial lesions progressed through small papules or vesicles before healing with atrophic scars.[academic.oup.com]
  • We report a case of photosensitivity occurred after a scorpion sting whose the clinical presentation is mimicking HV.[omicsonline.org]
Physician
  • The best-selling text has been completely revised and revitalised in this fifth edition, with the authors once again encouraging general practitioners, medical students, general physicians and early stage dermatology specialist trainees and interns to[books.google.com]
  • Occasionally a physician may prescribe steroid medications in severe cases. Use of pain and/or fever reducing OTC drugs may be helpful, too. One of it's forms can be the first sign of Lupus Erythematosus, but I did not find any connection to FMS.[forums.prohealth.com]
  • Phototherapy is recommended by some attending physicians to patients in order to desensitize the skin or to minimize the symptoms.[medicalfoxx.com]
  • Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com[academic.oup.com]
  • Astragalus can interfere with lithium, among other medications; speak with your physician. Preventive Measures: Always take medications only as prescribed, and avoid ultraviolet light exposure as much as possible while using known photosensitizers.[medigoo.com]
Fatigue
  • Immune Deficiency Syndrome (CFIDS) Chronic Fatigue Syndrome Chronic Hepatitis Chronic Obstructive Pulmonary Disease Chronic Pancreatitis Chronic Pelvic Pain Syndrome (in men) Chronic Prostatitis Cigarette Addiction Cigarette Smokers, Nutrition Cirrhosis[therapy.epnet.com]
  • The patient reported mild malaise and lethargy during vesicular phase of illness, but no other symptoms like fever or chills, burning in eyes, arthralgia, weight loss, easy fatiguability, bruising tendency, abdominal discomfort, or features suggestive[idoj.in]
  • It is most commonly used in combination with chemotherapy The radiation may be administered by a machine placed outside the body, or by placing a radioactive material inside the body The side effects of radiation therapy include nausea, vomiting, fatigue[dovemed.com]
  • In addition, the patient may suffer from general weakness and fatigue if he has complicated sunny dermatitis. The photo below shows how this allergy might look like.[acikgunluk.net]
  • […] varicella, scarlet fever, cellulitis, fifth disease, folliculitis Unexplained weight changes, menstrual irregularity, heat/cold intolerance Thyroid disease with secondary urticaria or xerosis Unexplained weight loss, night sweats, unexplained fevers, fatigue[aafp.org]
Falling
  • A natural fall in oestrogens may account for the tendency to remit after the menopause. Lehmann P, Schwarz T ; Photodermatoses: diagnosis and treatment. Dtsch Arztebl Int. 2011 Mar108(9):135-41. Epub 2011 Mar 4.[patient.info]
  • Symptoms An individual may fall anywhere between mild and severe on the photosensitivity spectrum. This means that they may need very little time in the sun to develop a rash, or a longer period of time than normal.[sunsaferx.com]
Chronic Fatigue Syndrome
  • Fatigue Syndrome Chronic Hepatitis Chronic Obstructive Pulmonary Disease Chronic Pancreatitis Chronic Pelvic Pain Syndrome (in men) Chronic Prostatitis Cigarette Addiction Cigarette Smokers, Nutrition Cirrhosis of the Liver Classic Migraine Climacteric[therapy.epnet.com]
Aspiration
  • The book has established a reputation as a ‘way of learning’ and as an accessible guide to the subject for the aspiring specialist.[books.google.com]
  • This can also help determine, if the cancer has spread to other organ systems Brain MRIs are used if neurological symptoms are present, which can help determine if the cancer has spread to the brain, or to tissues that cover the brain Bone marrow aspiration[dovemed.com]
Rhinitis
  • A secondary symptoms of hayfever which can often cause more discomfort than the primary allergic reaction is Rhinitis Dermatitis.[skinmagazine.co.uk]
  • ., allergic rhinitis, asthma) Involvement of flexor wrists and ankles, as well as antecubital and popliteal fossae Bullous pemphigoid Initially pruritic urticarial lesions, often in intertriginous areas Formation of tense blisters after urticaria Cutaneous[aafp.org]
Sighing
  • *sigh* Tanna PMLE (or PLE) is an acquired disease and thought to be an allergic reaction following the interaction of (ultraviolet A/UV-A) sunlight with proteins in the skin.[forums.prohealth.com]
Nausea
  • The rash usually appears on sun-exposed portions of the neck, upper chest, arms and lower legs, and may be accompanied by one to two hours of chills, headache and nausea.[mysunallergy.com]
  • Itchy, scaly, blisters, or raised areas Lesions that appears like an eczema Hyperpigmented discoloration of the skin Outbreaks in areas of skin which are overexposed to UV light Pain, erythema, and swelling in affected areas Chills, headache, fever, and nausea[medicalfoxx.com]
  • […] like eczema rashes There may be dry and scaly abnormal areas on skin In chronic cases, the skin may become thick and elicit scarring Hives may also form Skin with photodermatitis blisters/rashes may elicit burning sensations Fever and chills, headache, nausea[healthmomma.com]
  • Chills, headache, fever, and nausea in some cases. Long term effects include thickening and scarring of the skin and an increased risk of skin cancer, if the cause is genetic.[medigoo.com]
  • . • may be accompanied by chills, headache and nausea. • through repeated sun exposure, the person may become less sensitive to sunlight and the PMLE rash may disappear completely or gradually become less severe.[shirudo.com]
Corneal Opacity
  • In severe cases, hand and face deformities and corneal opacity may develop. hy·dro·a vac·ci·ni·for·me ( hī-drō'ă vak-sin-i-fōr'mē ) A recurrent eruption of erythema evolving to umbilicated bullae, occurring on exposure to the sun and affecting chiefly[medical-dictionary.thefreedictionary.com]
Photosensitivity
  • Offering broad coverage of the basic, clinical and curative aspects of photomedicine, this reference reflects the recent expansion of knowledge on the effects of light on normal skin as well as photosensitivity disorders and the use of light in treating[books.google.com]
  • THE diagnosis of cutaneous porphyria is suggested by the clinical findings of photosensitivity, hyperpigmentation, hirsutism and increased fragility of the skin.[nejm.org]
  • Figure: 1 Photosensitive distribution The red areas show those parts of the face most affected by photo-sensitive dermatoses Figure: 2 Drug-induced photosensitivity Note the relative sparing of photo-protected areas Figure: 3 Airborne contact dermatitis[pcds.org.uk]
  • Photosensitivity Who gets photosensitivity ? Photosensitivity occurs in males and females of all races and at all ages. Different types of photosensitivity may be prevalent at different times of life. Genetic and environmental factors are involved.[dermnetnz.org]
  • Classifications of photosensitivity: Exogenous photodermatoses: This is when a photosensitive reaction is caused by an outside photosensitizer.[sunsaferx.com]
Blister
  • Small red pimples and blisters appear on the skin usually within 1 to 4 days after exposure to sunlight. They typically disappear within 2 weeks, as skin becomes conditioned (thickened) known as "hardening phenomenon".[forums.prohealth.com]
  • When exposed to UV while some sensitive people it may occur redness and blisters (vesicles and pustules). Rash accompanied by severe itching. Later in the affected areas of skin pigmentation is long.[survincity.com]
  • Why do some people smooth and beautiful tan, even nauchivshis spirits, and other blister? Sometimes this is due to the presence of any chronic diseases, especially liver or adrenal glands.[qsota.com]
  • Treatment guide The application of cool, wet dressings are found helpful to relieve blisters or any skin eruptions due to UV exposure.[medicalfoxx.com]
  • This usually causes an itchy red rash or tiny blisters. In some cases, eruption spreads to skin covered by clothing.[mysunallergy.com]
Eczema
  • Eczema is caused due to an overactive response by the body’s immune system to an irritant. Some of the below factors can make a person more likely to suffer from eczema.[drhealthclinic.com]
  • […] and Skin Diseases Atopic dermatitis - children - homecare (Medical Encyclopedia) Atopic dermatitis -- self-care (Medical Encyclopedia) Atopic eczema (Medical Encyclopedia) Dyshidrotic eczema (Medical Encyclopedia) Nummular eczema (Medical Encyclopedia[icdlist.com]
  • 23 Feb 2015 • Nickel allergy • Tinea incognito • Infected eczema • Varicose eczema • Atrophie blanche • Asteatotic eczema Scalp conditions 22 Jan 2015 •Squamous cell carcinoma •Intradermal naevus •Actinic keratosis •Seborrhoeic keratosis •Scalp psoriasis[thepractitioner.co.uk]
  • The disorder usually begins in young and mid-adult life. synonyms Polymorphic Light Eruption, PMLE, Summer Eruption, Prurigo Aestivalis, Eczema Solare, Summer Prurigo UMLS Allergy to sunlight, Delayed photoallergic dermatitis, Eruption, polymorphous,[dermis.net]
  • Systemic and Cutaneous Diseases In this category, preexisting acne, herpes, or eczema is made worse by UV rays. What Are the Causes of Photodermatitis? There are actual photodermatitis causes beyond the categories explained above.[doctorshealthpress.com]
Eczema
  • Eczema is caused due to an overactive response by the body’s immune system to an irritant. Some of the below factors can make a person more likely to suffer from eczema.[drhealthclinic.com]
  • […] and Skin Diseases Atopic dermatitis - children - homecare (Medical Encyclopedia) Atopic dermatitis -- self-care (Medical Encyclopedia) Atopic eczema (Medical Encyclopedia) Dyshidrotic eczema (Medical Encyclopedia) Nummular eczema (Medical Encyclopedia[icdlist.com]
  • 23 Feb 2015 • Nickel allergy • Tinea incognito • Infected eczema • Varicose eczema • Atrophie blanche • Asteatotic eczema Scalp conditions 22 Jan 2015 •Squamous cell carcinoma •Intradermal naevus •Actinic keratosis •Seborrhoeic keratosis •Scalp psoriasis[thepractitioner.co.uk]
  • The disorder usually begins in young and mid-adult life. synonyms Polymorphic Light Eruption, PMLE, Summer Eruption, Prurigo Aestivalis, Eczema Solare, Summer Prurigo UMLS Allergy to sunlight, Delayed photoallergic dermatitis, Eruption, polymorphous,[dermis.net]
  • Systemic and Cutaneous Diseases In this category, preexisting acne, herpes, or eczema is made worse by UV rays. What Are the Causes of Photodermatitis? There are actual photodermatitis causes beyond the categories explained above.[doctorshealthpress.com]
Skin Lesion
  • Persistent fever, wasting, spleen and liver enlargement usually develop and skin lesions continue to appear irrespective of sun exposure.[clinicaladvisor.com]
  • Table 1 Clinical data of 20 Mexican children with HVLL Figure 1 Skin lesions in HVLL. (A-B) Multiple skin lesions in face and ear lobes characterized by vesicles, erythema, and crusts.[bloodjournal.org]
  • Abstract Hydroa Vacciniforme (HV) is a rare, acquired and chronic paediatric disorder that is characterized by photosensitivity and recurrent crops of skin lesions on sun-exposed skin, such as the face, ears and hands that heal with vacciniforme scarring[scopemed.org]
  • The patient was treated with Chinese herbal drugs and her skin lesions waxed and waned.[thedoctorsdoctor.com]
Neglect
  • المحتويات Lithogenic Potential Decreased with Chenodeoxycholic Acid 170 Health of Children 181 The Health of American Indian Children 182 A Survey of Current Problems and Needs 193 The Working Mother and Child Neglect on the Navajo Reservation 204 Health[books.google.com]
  • A neglected sub set of cutaneous lupus erythematosus: report of 40 cases. Arch Dermatol 136: 1033–1041 PubMed CrossRef Google Scholar 24. Lehmann P. (1996) Photosensitivität des Lupus erythematodes. Aktuelle Dermatol 22: 47–51 Google Scholar 25.[link.springer.com]
  • Pruritus in dialysis patients: a neglected problem. Nephrol Dial Transplant. 1995;10(12):2174–2176. 26. Jones EA, Bergasa NV. The pruritus of cholestasis and the opioid system. JAMA. 1992;268(23):3359–3362. 27. Fleischer AB Jr.[aafp.org]

Treatment

  • Readers are guided through the maze that too often lies between the presenting skin complaint and its final diagnosis and treatment.[books.google.com]
  • Individuals may die in very rare cases with treatment failure.[medicalfoxx.com]
  • treatment and/or systemic treatment, when the whole body is affected In some children, the condition progresses rapidly, while in others the progress is slower.[dovemed.com]
  • UVA/UVB. [ 1, 11 ] Psoralen combined with UVA (PUVA) treatment. [ 9 ] Recently, light-emitting diode (LED) treatment has also been suggested. [ 12 ] Beta carotene and hydroxychloroquine can both improve tolerance to the sun.[patient.info]
  • Woodburne A.R., Philpott O.S., Philpott J.A. (1964) Quinacrine (Atabrine) in treatment of solar dermatoses.[link.springer.com]

Prognosis

  • Prognosis - Hydroa vacciniforme Not supplied. Treatment - Hydroa vacciniforme Not supplied. Resources - Hydroa vacciniforme Not supplied.[checkorphan.org]
  • The prognosis of the condition is poor; only 1 in 3 survive after 2 years of diagnosis The prognosis depends upon a set of several factors, which include: Stage of tumor: With lower-stage tumors, when the tumor is confined to site of origin, the prognosis[dovemed.com]
  • The aggressive types of extra ocular sebaceous neoplasm are reported with lymph node and visceral metastasis associated with poor prognosis.[ingentaconnect.com]
  • , What to Expect at Your Provider’s Office, Treatment Options, Prognosis/Possible Complications at Photodermatitis : Signs and Symptoms, Complementary and Alternative Therapies, Herbs, Homeopathy, Prognosis/Possible Complications, Supporting Research[medicalfoxx.com]
  • Prognosis Most patients can control their PMLE with simple treatments. [ 9 ] The condition is likely to ease as the spring and summer advance; however, it will probably recur the following year unless precautions are taken.[patient.info]

Etiology

  • The etiology is unknown.[skincareguide.ca]
  • Table 1 includes historical findings that suggest etiologies for pruritus. Enlarge Print Table 1.[aafp.org]
  • The etiology of the condition is still unknown; there is theory of an abnormal sensitivity to the UVA (Ultraviolet rays type A) radiation in a range of 320 to 390 nm of wavelength.[oxyhives.org]
  • […] and Mexico Epidemiology Mainly children and adolescents from Asia, or Native Americans from Central and South America, and Mexico Rare in adults Sites Sun exposed skin, particularly the face (cheeks, nose, lower lip) but also ears and dorsum of hands Etiology[pathologyoutlines.com]
  • Options, Prognosis/Possible Complications at Photodermatitis : Signs and Symptoms, Complementary and Alternative Therapies, Herbs, Homeopathy, Prognosis/Possible Complications, Supporting Research at Skin Disorders, Photodermatitis - Overview, Definition, Etiology[medicalfoxx.com]

Epidemiology

  • Papulovesicular eruption resulting in ulceration and scarring Wasting Diagnostic Exams Flow cytometry Immunohistochemistry Immunophenotyping Progression and Transformation Recurrent skin lesion s for 10-15 years before progression to system ic involvement Epidemiology[seer.cancer.gov]
  • Occurs in children and associated with sun sensitivity ( WHO 2008 ) Increased frequency in Asians and Native Americans from Central and South America, and Mexico Epidemiology Mainly children and adolescents from Asia, or Native Americans from Central[pathologyoutlines.com]
  • Epidemiology It is a fairly common condition, perhaps affecting 15% of people in the UK.[patient.info]
  • Pipelzadeh MH, Jalali A, Taraz M, Pourabbas R, Zaremirakabadi A (2007) An epidemiological and a clinical study on scorpionism by the Iranian scorpion Hemiscorpius lepturus. Toxicon 50: 984-992.[omicsonline.org]
  • […] type Mycosis fungoides Precursor T-cell lymphoblastic lymphoma Peripheral T-cell lymphoma, not otherwise characterized Primary cutaneous anaplastic large cell lymphoma Subcutaneous panniculitis-like T-cell lymphoma Lupus [10] Herpes simplex [11] [1] Epidemiology[wikidoc.org]
Sex distribution
Age distribution

Pathophysiology

  • Therapies, Herbs, Homeopathy, Prognosis/Possible Complications, Supporting Research at Skin Disorders, Photodermatitis - Overview, Definition, Etiology Risk Factors, Signs and Symptom,s Differential Diagnosis, Diagnosis, Physical Examination, Pathology/Pathophysiology[medicalfoxx.com]
  • The pathophysiology differs in these disorders but photoprotection is the most integral part of their management.[ijdvl.com]
  • Part 1: pathophysiology and technical aspects of photobiologic studies. Actas Dermosifiliogr 105: 112-121.[omicsonline.org]
  • Historical Perspective HVLL reports date back to 1986; [5] however, it is not until 2008 that the WHO recognized HVLL as a separate entity from Hydroa vacciniforme and classified it under "EBV positive T-cell lymphoproliferative disorders of childhood". [2] Pathophysiology[wikidoc.org]
  • Pathophysiology The etiology of hydroa vacciniforme (HV) is uncertain. HV may be a distinct entity distinguished by scarring or may occur within the spectrum of polymorphous light eruption.[emedicine.medscape.com]

Prevention

  • Cachexia Calcium Oxalate Stones Cancer Prevention (Reducing the Risk) Cancer Treatment Support Candida Candida/Yeast Hypersensitivity Syndrome Canker Sores Car Sickness Cardiac Arrhythmia Cardiac Autonomic Neuropathy, Diabetic Cardiomyopathy Caries, Prevention[therapy.epnet.com]
  • Treatment – A cool bath – Calming and anti-itching bath soaks – Aloe vera gel – Calamine lotion Prevention – Loose cotton clothing – Cool shower immediately after excessive sweating – A night fan for cool air circulation[skinmagazine.co.uk]
  • This may prevent or reduce the number of recurrences of the condition. Oral medication may be useful in reducing outbreaks but does not reliably prevent hydroa vacciniforme lesions.[dermnetnz.org]
  • It has been suggested that 17β-estradiol somehow prevents this response, thus leading to PMLE.[patient.info]
  • It can be prevented by getting graded and gradual exposures. Tanning booths should help to prevent PVLE if used with care. Treatment is symptomatic.[vgrd.org]

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