Presentation
Diagnosis was challenging as this condition presents with multiple neuropathies, and attempting to diagnose based on clinical symptoms was often misleading. [ncbi.nlm.nih.gov]
Respiratoric
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Hoarseness
An elderly man presented with severe right ear pain and discharge, hoarseness and dysphagia causing significant involuntary weight loss. [ncbi.nlm.nih.gov]
Voice was hoarse. Right 7th,9th and 10th cranial nerve palsies were noted. Blood urea was 22 mg/dl,random blood sugar was 132 mg/dl CSF: 4 cells/c.mm, all lymphocytes, proteins 58 mg/dl and glucose 73 mg/di. Hemoglobin was 8.8 gms. [ijdvl.com]
A 22-year-old male student, with no significant past history of any medical illness, presented with a history of acute onset hoarseness of voice and binocular diplopia since 10 hours and severe hypophonia with dysphagia since 4 hours. [annalsofian.org]
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Nasal Voice
A 52-year-old man developed diplopia, a nasal voice, dysphagia, hoarseness and slight bilateral facial palsies. There was no ataxia, areflexia, limb weakness or sensory involvement. Serum anti-GQ1b IgG antibody was present. [ncbi.nlm.nih.gov]
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Sputum
On examination he was conscious, febrile, and coughing brought mucopurulent sputum. Herpetic lesions were present over the right ear. There was associated dysphagia and hoarseness of voice. The 8t, 9th and 10th cranial palsies were noted. [ijdvl.com]
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Hypophonia
A 22-year-old male student, with no significant past history of any medical illness, presented with a history of acute onset hoarseness of voice and binocular diplopia since 10 hours and severe hypophonia with dysphagia since 4 hours. [annalsofian.org]
Neurologic
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Numbness of the Hand
She remained in hospital for 2.5 months and then returned to work after 18 months with residual numbness in the hands and feet. [academic.oup.com]
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Cranial Nerve Finding
These transient acute cranial nerve findings in patients with vestibular vertigo support the concept of inflammatory polyneuritis, and preliminary studies indicate that an anti-inflammatory agent such as prednisone may be the preferred treatment. [ncbi.nlm.nih.gov]
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Rabies
Abstract Encephalitis and polyneuritis occurring after rabies vaccination are believed to be immunologically mediated. [ncbi.nlm.nih.gov]
Workup
[…] enzyme level Lyme serology Thyroid function tests Hepatitis workup Vitamin B-12 and folic acid levels In patients with B-12 levels below 350 pg/mL, homocysteine and methylmalonic acid levels are more sensitive indicators of a deficiency. [emedicine.medscape.com]
Microbiology
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Borrelia Burgdorferi
In each case polyneuritis cranialis was caused by infection with Borrelia burgdorferi. Therapy with penicillin proved to be effective. [ncbi.nlm.nih.gov]
Patient also tested negative for human immunodeficiency virus (HIV), antinuclear antibody (ANA) by immunofluorescence, venereal disease research laboratory (VDRL) antibody, acetylcholine esterase (ACE), and antibodies against borrelia burgdorferi. [annalsofian.org]
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Rickettsia Conorii
Rickettsia conorii is endemic in the Mediterranean region. Infections are mostly benign and neurological involvement is unusual. [ncbi.nlm.nih.gov]
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Complement Fixing Antibody
Complement fixing antibodies to CMV remained stable throughout the illness at a relatively low titer. [ncbi.nlm.nih.gov]
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Herpes Simplex Virus Type 2
Among the viruses, the varicella zoster virus, the Epstein-Barr virus, the cytomegalovirus, the HI virus and the herpes simplex virus type 2, among the bacteria the Mycobacterium leprae, the Corynebacterium diphtheriae, brucelae and mycoplasmas. [educalingo.com]
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Francisella Tularensis
Wound culture returned positive for Francisella tularensis ; he was treated with 20-day course of doxycycline. [n.neurology.org]
HLA Type
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HLA-Dw3
The total patient group showed significant increases in HLA-AW30, HLA-AW31, and HLA-DW3. [ncbi.nlm.nih.gov]
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HLA-B8
Patients with chronic relapsing polyneuritis showed a definite association with HLA-AW30 and AW31 and probable associations with HLA-B8, HLA-DW3, and glyoxalase I. [ncbi.nlm.nih.gov]
Treatment
Due to misdiagnosis resulting in delayed treatment, peripheral facial paralysis was left as the main sequelae, while other symptoms responded quickly to treatment. After a 6-month follow-up, facial palsy was still present. [ncbi.nlm.nih.gov]
Different doctors have different approaches to treatment and differing experiences with patients, and multiple opinions may help a patient arrive at the best treatment plan. [wisegeekhealth.com]
The easiest part of this treatment is that these corticosteroids can be taken orally. [epainassist.com]
Prognosis
The prognosis of most cases was benign, irrespective of age, sex and tetanus vaccination history. Cases with delayed recovery only occurred during the summer months. [ncbi.nlm.nih.gov]
the patients might obtain relief from Peripheral Neuropathy Please find comprehensive information on Peripheral Neuropathy regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis [dovemed.com]
Thus determined to a certain extent and prognosis of neuritis and polyneuritis, because the hole damaged the nerve trunks, particularly the brachial plexus, accompanied by degeneration, always uncertain as to the completeness and quality of the restoration [minclinic.ru]
Cranial nerve palsies due to herpes zoster are reported to have good prognosis. [2] About 55% of patients with motor deficit are said to recover completely and in 30% recovery may be partial. [3] All three of our patients showed normal palatal movements [ijdvl.com]
Prognosis : poor. Pathogenesis Etiology Obscure, but lesions strongly suggest an infectious/immune-mediated mechanism causing a polyneuropathy. [vetstream.com]
Etiology
Polyneuritis has no single cause and the etiology is rather difficult to determine. [hubpages.com]
Pathogenesis Etiology Obscure, but lesions strongly suggest an infectious/immune-mediated mechanism causing a polyneuropathy. [vetstream.com]
We discuss such a case due to an unsuspected etiology. [annalsofian.org]
Many new clinical syndromes have emerged; the pathologico-histologic changes underlying them have been described, and entirely new conceptions of etiology have become prevalent. [jamanetwork.com]
demyelinating vs. axonal), by etiology, or by pattern of inheritance. [fpnotebook.com]
Epidemiology
The committee uses no specific algorithm or diagnostic criteria for every case but comes to a consensus on the most likely diagnosis on the basis of clinical, laboratory, and epidemiologic data. [wwwnc.cdc.gov]
Enviromnental Health 22 Department of Neurology, Tenri Hospital 23 Department of Neurology, Kanazawa Medical University 24 Department of Neurology, Tokyo Metropolitan Neurological Hospital 25 Department of Neurology, Jichi Medical School 26 Department of Epidemiology [webview.isho.jp]
[…] corresponds with the number of nerves involved: Mononeuropathy: a single nerve is affected Mononeuropathia multiplex: several nerves are affected Polyneuropathy: a number of nerves are affected making it no longer possible to determine which ones are involved Epidemiology [lecturio.com]
Distal epidermal denervation has been shown to be associated with distal painful sensorimotor polyneuropathy. [13] Other factors may be involved, including nutritional and vitamin deficiencies (eg, vitamin B-12). [14] Epidemiology Distal painful sensorimotor [emedicine.medscape.com]
Epidemiological studies on CIDP report an incidence in Northern Italy around 0.6 cases per 100.000 [ 4 ]. [hindawi.com]
Pathophysiology
Painful Diabetic Polyneuropathy covers all aspects of these painful disorders from pathophysiology and diagnosis, treatment and prevention, future approaches and the nursing perspective, to billing issues and the patient’s experience. [books.google.de]
Pathophysiology A granulomatous polyneuritis. Although cauda equina involvement appears to lead to the major clinical signs, it is not uncommon for there to be cranial and other peripheral nerve involvement. [vetstream.com]
Bench-to-bedside review: mobilizing patients in the intensive care unit–from pathophysiology to clinical trials. [lifeinthefastlane.com]
Pathophysiology Small fiber neuropathy typically involves distal degeneration of small or unmyelinated nerve fibers. [emedicine.medscape.com]
Use of inhaled anaesthetic agents has no clinical implications related to the pathophysiology of GBS. [omicsonline.org]
Prevention
However, a disruption to these nerves causes an interruption to the communication preventing the message from being delivered This may lead to signs and symptoms such as pain, lack of coordination, trouble with sleep, loss of appetite, and an inability [dovemed.com]
As the Chronic Inflammatory Polyneuritis is diagnosed at an early stage, preventive treatment is provided to make sure that the axons of the nerves can be prevented from loss. [epainassist.com]
Painful Diabetic Polyneuropathy covers all aspects of these painful disorders from pathophysiology and diagnosis, treatment and prevention, future approaches and the nursing perspective, to billing issues and the patient’s experience. [books.google.de]
Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. [books.google.it]
Evaluation Exercise Equipment Mobility Modalities Orthopedics Pediatrics Rehab Supplies Sensory Motor Splinting Tourniquet and Cuff Treatment Furniture Wheelchair Wound & Scar Care Dental Education and Marketing Exam and Hygiene Gifts Home Care and Preventive [berktree.com]