Accelerated growth in the absence of DNA replication origins. Nature. 2013;503:544–7. View Article PubMed PubMed Central Google Scholar Jensen MR, Løbner-Olesen A, Rasmussen KV. [biologydirect.biomedcentral.com]

Global gene expression analyses of tetraploid endothelial cells revealed a dysfunctional phenotype characterized by a cell cycle arrest profile (decreased CCNE2/A2, RBL1, BUB1B; increased CDKN1A) and increased expression of genes involved in inflammation [ncbi.nlm.nih.gov]

Years Published 1989, 2003, 2016 The information in NORD’s Rare Disease Database is for educational purposes only and is not intended to replace the advice of a physician or other qualified medical professional. [rarediseases.org]

Jeanne Ropars, Ying‐Chu Lo, Emilie Dumas, Alodie Snirc, Dominik Begerow, Tanja Rollnik, Sandrine Lacoste, Joëlle Dupont, Tatiana Giraud and Manuela López‐Villavicencio, Fertility depression among cheese‐making Penicillium roqueforti strains suggests degeneration [doi.org]

Cervical and anogenital cancers are induced by the high-risk types of human papillomavirus (HPV). The HPV E6 oncoprotein induces polyploidy in human keratinocytes, yet the mechanism is not known. [ncbi.nlm.nih.gov]

Not to be confused with "polypoid", resembling a polyp. This image shows haploid (single), diploid (double), triploid (triple), and tetraploid (quadruple) sets of chromosomes. Triploid and tetraploid chromosomes are examples of polyploidy. [en.wikipedia.org]