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Polyserositis


Presentation

  • To the best of our knowledge, this is a first report describing pleuritis and pericarditis as an initial presentation of mucinous cystadenoma of an appendix.[ncbi.nlm.nih.gov]
  • Abstract We present a 46-year-old patient who underwent an abdominal hysterectomy with bilateral salpingo-oophorectomy for persistent trophoblastic disease.[ncbi.nlm.nih.gov]
  • Abstract A 36-year-old male of pure Japanese ancestry presented with a classical 20-year history of Recurrent Polyserositis manifested by self-limited attacks of fever plus pleuritis, peritonitis or arthritis.[ncbi.nlm.nih.gov]
  • We present a brief review of the literature and attract attention to the need for close observation of patients with schistosomiasis who are treated with praziquantel.[ncbi.nlm.nih.gov]
  • The observation in the present study of the occurrence of the more severe forms of the disease in the familial cases compared to the non-familial, isolated cases, make a polygenic type of inheritance or an autosomal inheritance where the penetrance of[ncbi.nlm.nih.gov]
Fever
  • Abstract The authors report an unusual case of bilateral short term acute orchitis in a patient with recurrent polyserositis (familial Mediterranean fever).[ncbi.nlm.nih.gov]
  • […] and caused by MEditerranean FeVer gene (MEFV) mutations.[readbyqxmd.com]
  • Question An 8 years old girl presented with recurrent fever for past 1 month. She had an exanthematous rash 2 months ago along with fever that subsided in 3 days. Now she has fever with chills and rigors for one week.[pediatriconcall.com]
  • Abstract A 36-year-old male of pure Japanese ancestry presented with a classical 20-year history of Recurrent Polyserositis manifested by self-limited attacks of fever plus pleuritis, peritonitis or arthritis.[ncbi.nlm.nih.gov]
  • Gastrointestinal effects of long-term colchicine therapy in patients with recurrent polyserositis (Familial Mediterranean Fever).[diki.pl]
Sepsis
  • Abstract A 24-year-old woman was admitted to our department with sepsis, polyserositis and suspected abdominal tumor immediately after delivery. Effusion analyses suggested an etiology of tuberculosis.[ncbi.nlm.nih.gov]
  • Polverosa most common tuberculosis and rheumatism, rarely in systemic lupus erythematosus, sepsis, pneumonia, uremia. The clinical course of the disease can be acute (in exudative polyserositis) and chronic (when the adhesive polyserositis).[medicalency.com]
  • Polyserositis most commonly found in tuberculosis and rheumatism, sometimes with systemic lupus erythematosus, sepsis, pneumonia, uremia.[survinat.com]
Pleuritic Pain
  • Lupus pneumonitis Acute: 12% of active lupus fever,pleuritic pain,dyspnoea,cough, cyanosis B/L pulmonary infiltrates and effusion HP:alveolar damage,interstitial edema,hyaline membranes perivascular lymphocytic & plasma cell infiltrates- clear or persist[de.slideshare.net]
Abdominal Distension
  • Other symptoms or signs included purulent pleurisy, orthopnea, restricted activity, distant heart sounds, purulent pericarditis, abdominal distension, and hepatomegaly...[readbyqxmd.com]
Tachycardia
  • Abstract A dose-dependent cutaneous leukocytoclastic vasculitis developed in a 34 year old man who was given amiodarone for supraventricular tachycardias resistant to other drugs.[ncbi.nlm.nih.gov]
  • ) 20 ve Urine: SG 1.005 USG Abdomen:Hepatomegaly pH 7.0 RK 10.8x4 WBC 1 LK 10.7x4 RBC nil No ascites Nitrite neg VDRL : Reactive Protein neg HIV I&II neg Glucose neg RFT&LFT normal Ketones neg HBsAg neg Urobil,BS,BP neg Blood C/S no growth ECG:Sinus tachycardia[de.slideshare.net]
Photosensitivity
  • During previous treatment periods with amiodarone, the patient had experienced photosensitivity and dose-dependent polyserositis.[ncbi.nlm.nih.gov]
  • DIAGNOSTIC CRITERIA MALAR RASH-ERYTHEMA OVER MALAR EMINENCE DISCOID RASH-ERYTHEMATOUS RAISED PATCH WITH FOLLICULAR PLUGGING PHOTOSENSITIVITY ORAL ULCERS ARTHRITIS-NONEROSIVE ARTHRITIS SEROSITIS-PLEURITIS , PERICARDITIS RENAL DISORDER-PROTEINURIA 0.5G[slideshare.net]
  • ARA criteria for SLE Malar rash Discoid rash Photosensitivity Oral ulcers Arthritis Serositis Renal disorders Neurological disorder Hematological disorder Immunological disorder ANA / 4 documented,present any time in a patient 95%specific & 75% sensitive[de.slideshare.net]
Seizure
  • These side effects include agranulocytosis, seizures, and cardiorespiratory symptoms.[ncbi.nlm.nih.gov]
  • CLINICAL FEATURES: Neurologic Behavior/Personality changes, depression Cognitive dysfunction Psychosis Seizures Stroke Chorea Pseudotumor cerebri Transverse myelitis Peripheral neuropathy Total of 19 manifestations described May be difficult to distinguish[slideshare.net]
  • Given the febrile characteristics of the disease one would expect higher frequency of febrile seizure in this group of pediatric patients. OBJECTIVES: To evaluate the frequency of febrile seizure and related factors in patients with FMF.[readbyqxmd.com]

Workup

Suppression
  • These attacks were completely suppressed by daily prophylactic colchicine, but recurred when the drug was briefly discontinued. For the past 10 years he has been on 1.2 mg of colchicine daily and has had no further febrile attacks.[ncbi.nlm.nih.gov]
Normocytic Anemia
  • The patient had elevated erythrocyte sedimentation rate (ESR), increased C-reactive protein (CRP) and normocytic anemia.[ncbi.nlm.nih.gov]
Hepatic Necrosis
  • Complications are rare,and include Hepatitis,Hepatic necrosis, Pericarditis, Myocarditis, Glomerulonephritis, Interstitial nephritis,Pneumonian and Interstitial pneumonitis(5).Treatment is supportive with reassurance in uncomplicated cases.[shmabstracts.com]

Treatment

  • During previous treatment periods with amiodarone, the patient had experienced photosensitivity and dose-dependent polyserositis.[ncbi.nlm.nih.gov]
  • The literature is reviewed and the treatment implications are discussed.[ncbi.nlm.nih.gov]
  • Abstract A case report describes an adolescent girl with a treatment-resistant bipolar disorder, who developed pericarditis and polyserositis while being treated with clozapine.[ncbi.nlm.nih.gov]
  • To the best of our knowledge, the wide spectrum of side effects, the short time lapse after onset of chemotherapy, and their severity are uncommon in a patient receiving her first chemotherapeutic treatment with MTX.[ncbi.nlm.nih.gov]
  • The same diagnosis was established in her newborn infant, who responded well to antituberculosis treatment.[ncbi.nlm.nih.gov]

Prognosis

  • Links: aetiology pathology clinical features investigations diagnosis treatment prognosis[gpnotebook.co.uk]
  • Diagnosis is one of exclusion D/D Infective consolidation Pulmonary hemorrhage Treatment: acute-steroids,immunosuppressants if steroid unresponsive chronic-asymptomatic:no treatment;poor prognosis if PFT abn Prognosis: poor; 50% mortality sequelae for[de.slideshare.net]
  • The prognosis depends on the underlying disease, a chronic form - to the degree of development of adhesions and violations functions of the respective bodies. Treatment is primarily the underlying disease, usually complex.[medicalency.com]
  • Prognosis for life is dependent on the underlying disease, and the chronic form — on the extent of adhesions and the dysfunction of the relevant authorities. Treatment of the underlying disease in the first place, as a rule, complex.[survinat.com]
  • The prognosis of tuberculosis of intrathoracic lymph nodes, especially small form - favorable, with complete resorption of specific inflammation of the lymphoid tissue and recovery.[medicalformat.com]

Etiology

  • Effusion analyses suggested an etiology of tuberculosis. The severe general condition of the patient allowed for no invasive diagnostic procedures. Antituberculosis therapy was administrated too late and was of no benefit.[ncbi.nlm.nih.gov]
  • Describes polverosa unclear etiology - the so-called periodic disease, family recurring P.[medicalency.com]
  • It may also facilitate prompt administration of steroids after alternate etiologies of inflammation have been ruled out.[jmedicalcasereports.biomedcentral.com]
  • When P. tubercular etiology on combined specific treatment streptomycin (1 g per day), Pasco (12 g), ftivazid (1.5 g). When polyserositis rheumatic etiology — antirheumatic treatment (Salicylates, antibiotics).[survinat.com]
  • […] the disease is a recurrent inflammation of the serous membranes, we have designated it "recurrent polyserositis." 9 Although usually of benign nature, recurrent polyserositis is sometimes fatal because of renal failure due to amyloidosis. 10-12 The etiology[jamanetwork.com]

Epidemiology

  • EPIDEMIOLOGY Prevalence influenced by age, gender, race, and genetics Prevalence: 1:2000 Peak incidence 14-45 years Black White (1:250 vs. 1:1000) Female predominance 10:1 HLA DR3 association, Family History Severity is equal in male and female 31.[slideshare.net]
  • In Armenian persons (based on epidemiology among Armenian populations in Lebanon and southern California), the estimated prevalence of FMF is 1 case per 500 population, with a gene frequency of 1 per 7.[emedicine.medscape.com]
  • Epidemiology FMF is common in people from eastern Mediterranean countries but is not restricted to these ethnic groups. [ 5 ] Male-to-female ratio is 1.5-2:1. Presentation [ 6 , 7 , 8 ] The majority present in the first decade of life.[patient.info]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology Associated with mutations in the MEFV (Mediterranean fever) gene located on chromosome 16. [ 2 ] Although FMF was originally defined as an autosomal recessive disorder, approximately 10-20% of FMF patients do not carry any FMF gene (MEFV[patient.info]

Prevention

  • Now in its second edition, this popular and essential comprehensive resource provides a detailed analysis of how to identify, prevent, and manage drug-induced diseases. Edited by James E. Tisdale and Douglas A.[books.google.de]
  • The PCV13 vaccine is now routinely given in series with the 23-valent pneumococcal polysaccharide vaccine (PPSV23) for prevention of community-acquired pneumonia in the elderly.[jmedicalcasereports.biomedcentral.com]
  • Treatment Colchicine is the mainstay of treatment - it is very effective, prevents attacks and helps symptoms.[patient.info]
  • […] name of contact person 名 ミドルネーム 姓 Atsushi Kawakami 組織名/Organization 長崎大学大学院医歯薬学総合研究科 Nagasaki University Graduate School of Biomedical Sciences 部署名/Division name 先進予防医学共同専攻(リウマチ・膠原病内科) Department of Immunology and Rheumatology, Division of Advanced Preventive[upload.umin.ac.jp]

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