Acute myeloid leukemia presenting as polyserositis and leukemia cutis. Clin Cancer Investig J 2016;5:284-6 How to cite this URL: Saxena A, Bodkhe S, Kulkarni AR, Jain AP. Acute myeloid leukemia presenting as polyserositis and leukemia cutis. [ccij-online.org]

To the best of our knowledge, this is a first report describing pleuritis and pericarditis as an initial presentation of mucinous cystadenoma of an appendix. [ncbi.nlm.nih.gov]

Case Presentation: 34 yr old female with no past medical and surgical history was admitted with 4 days of vomiting, fever and shortness of breath. [shmabstracts.com]

The child with sJIA usually presents with a spiking fever pattern, evanescent rash, and arthralgias/arthritis. Other features often present are lymphadenopathy, hepatosplenomegaly, and polyserositis. [readbyqxmd.com]

This presents as polyarthritis or polyserositis. He provided early descriptions of hematogenous albuminuria, uremic pericarditis and progressive polyserositis. [diki.pl]

• Fever

  Commonly the condition is inherited and intermittent and is termed familial Mediterranean fever. [medicine.academic.ru]

  […] and caused by MEditerranean FeVer gene (MEFV) mutations. [readbyqxmd.com]

  Question An 8 years old girl presented with recurrent fever for past 1 month. She had an exanthematous rash 2 months ago along with fever that subsided in 3 days. Now she has fever with chills and rigors for one week. [pediatriconcall.com]

  Synonym: benign paroxysmal peritonitis, familial Mediterranean fever, familial recurrent polyserositis, Mediterranean fever, periodic peritonitis, periodic polyserositis. (05 Mar 2000) Polyserositis Pictures Click the following link to bring up a new [lexic.us]

• Weakness

  Interestingly, in our case, raised CK was only detected once, being moderately elevated at 492 IU/l despite profound generalised weakness. [nature.com]

  […] irregular heart beat) hepatosplenomegaly (enlargement of the liver and spleen) vesiculobullous rash (visible accumulation of fluid under the skin), eczema (skin rash), vasodilatation (widening of blood vessels) myopathy (aching muscles, muscle tenderness of weakness [mymemory.translated.net]

  Pleuro pulmonary manifestations of SLE Lupus pneumonitis Lymphocytic interstitial pneumonitis Pulmonary hemorrhage Pulmonary embolism associated with LA Pulmonary hypertension Pleuritis Weakness of diaphragm 38. [de.slideshare.net]

  H/O PRESENT ILLNESS H/O WEAKNESS IN USING RT UL AND LL H/O DEV.OF ANGLE OF MOUTH TO LEFT SIDE NO H/O BLURRING OF VISION NO H/O VERTIGO/TINNITUS NO H/O LOSS OF SENSATION OVER THE FACE NO H/O NASAL REGURGITATION NO H/O DEV OF TONGUE NO H/O BLADDER AND BOWEL [slideshare.net]

• Turkish

  The mortality rate among Turkish patients was high, but this high rate may have represented selection bias. No pre–colchicine-therapy data are available from Arabic patients. [emedicine.medscape.com]

• Pleuritic Pain

  Lupus pneumonitis Acute: 12% of active lupus fever,pleuritic pain,dyspnoea,cough, cyanosis B/L pulmonary infiltrates and effusion HP:alveolar damage,interstitial edema,hyaline membranes perivascular lymphocytic & plasma cell infiltrates- clear or persist [de.slideshare.net]

• Vomiting

  There is no cough, vomiting, bladder or bowel complaints. On examination, she had soft hepatomegaly. Other systems were normal. [pediatriconcall.com]

  Case Presentation: 34 yr old female with no past medical and surgical history was admitted with 4 days of vomiting, fever and shortness of breath. [shmabstracts.com]

  + + - - M; Male, F; Female All these patients had multiple episodes of vomiting and were in shock at the time of presentation. [apjmt.mums.ac.ir]

  Abdominal pain with signs of peritonitis - pain can originate in one area and then spread over the whole abdomen; may be mistaken for appendicitis, cholecystitis or renal colic; there may be associated constipation followed by diarrhoea; vomiting can [patient.info]

  NOT ASSOC.WITH LOC,HEADACHE OR VOMITING NOT ASSOC WITH BLURRING OF VISION NOT ASSOC.WITH CHEST PAIN ASSOC.WITH SPEECH DIFFICULTY 5. [slideshare.net]

• Nausea

  IM is a clinical triad of fever, sore throat, and lymphadenopathy.Headaches, myalgia, nausea, chills, arthralgia,jaundice and hepato‐splenomegaly can also occure.(4).Lab findings include leukocytosis with atypical T‐lymphocytes, heterophile antibodies [shmabstracts.com]

  AlP poisoning manifests with nausea, vomiting, hypotension and metabolic acidosis. Common complications are cardiac arrhythmia, acute renal failure, and hemorrhage with disseminated intravascular coagulopathy (3). [apjmt.mums.ac.ir]

• Chest Pain

  We present a 19-year-old man who was hospitalized due to chest pain following a progressive osteolysis of the bony thorax. The disease later expanded into the pleura, peritoneum and pericardium in a form of massive chylous polyserositis. [ncbi.nlm.nih.gov]

  Recurrent polyserositis is a disorder characterized by paroxysms of fever accompanied by abdominal and chest pain, due to inflammation of the peritoneum and the pleura. Pain in the joints and headache are frequently present during an attack. [jamanetwork.com]

  For acute P. characterized by chest pain, heart or abdomen, fever up to 38-40°, the gradual accumulation of fluid in the cavities. When the cavities takes a little, it is possible to listen noise of friction pleura, pericardium or even peritoneum. [medicalency.com]

  myalgia (aching muscles) nephrolithiasis (formation of kidney stones), hematuria (blood in the urine), proteinuria (excess protein in the urine), pollakiuria (increased frequency of urination) gynaecomastia (breast enlargement in men) chest pain, malaise [mymemory.translated.net]

• Back Pain

  However, the back pain did not improve and the patient received a donor lymphocyte infusion (1 × 10 7 CD3 + cells/kg). [nature.com]

• Skin Lesion

  Amyloidosis, skin lesions and arthritis may be seen in these patients. This condition occurs most often in non-Ashkenazi Jews, Armenians and Arabs. [gpnotebook.co.uk]

  Although the ANA was negative and only 3 of the ARA criteria are fulfilled, the authors made a presumptive diagnosis of SLE supported by the skin lesions and a positive lupus band test. [elsevier.pt]

  Skin and muscle involvement is less common. Here, we report four patients presented with skin lesions or myalgia. Most striking findings in those patients are the absence of other major criteria for FMF and dominancy of skin lesions or myalgia... [readbyqxmd.com]

  FMF is more common in individuals of Mediterranean ancestry, and is caused by mutations in the MEFV gene, resulting in fever, abdominal pain, and skin lesions; over 300 different mutations have been identified to date. [natureasia.com]

  In leukemia, a wide spectrum of skin lesions including papules, macules, plaques, or nodules which may be skin-colored to erythematous or violaceous colored, generalized urticaria, exanthematous eruptions, purpura, Sweet's syndrome like lesions, leukocytoclastic [ccij-online.org]

• Eruptions

  The symptoms consisted of fever; abdominal, chest, and joint pains; and skin eruptions. The clinical manifestations often simulated those of acute rheumatic fever, particularly since cardiac murmurs occurred in more than half of the patients. [pediatrics.aappublications.org]

  In leukemia, a wide spectrum of skin lesions including papules, macules, plaques, or nodules which may be skin-colored to erythematous or violaceous colored, generalized urticaria, exanthematous eruptions, purpura, Sweet's syndrome like lesions, leukocytoclastic [ccij-online.org]

• Skin Rash

  (visible accumulation of fluid under the skin), eczema (skin rash), vasodilatation (widening of blood vessels) myopathy (aching muscles, muscle tenderness of weakness, not caused by exercise) kidney pain not known: Last Update: 2012-04-10 Usage Frequency [mymemory.translated.net]

• Pruritus

  verisuonten laajeneminen myopatia (lihassärky tai lihasten arkuus tai heikkous, ei liikunnan aiheuttama) munuaiskipu tuntemattomat: English 148 hepatitis (inflammation of the liver) urticaria (itchy rash), alopecia (unusual hair loss or thinning), pruritus [mymemory.translated.net]

• Alopecia

  […] rakkulainen ihottuma (nesterakkulat), ekseema, verisuonten laajeneminen myopatia (lihassärky tai lihasten arkuus tai heikkous, ei liikunnan aiheuttama) munuaiskipu tuntemattomat: English 148 hepatitis (inflammation of the liver) urticaria (itchy rash), alopecia [mymemory.translated.net]

• Pericardial Calcification

  […] due to pericarditis I31.1 ICD-10-CM Diagnosis Code I31.1 Chronic constrictive pericarditis 2016 2017 2018 2019 Billable/Specific Code Applicable To Concretio cordis Pericardial calcification pericardial I31.1 ICD-10-CM Diagnosis Code I31.1 Chronic constrictive [icd10data.com]

During previous treatment periods with amiodarone, the patient had experienced photosensitivity and dose-dependent polyserositis. [ncbi.nlm.nih.gov]

Shown restorative treatment (vitamins, diet, and others). At considerable accumulation of serous fluid in the cavities - puncture. Treatment of recurrent disease (aspirin, gistaglobin, nipagin) ineffective. [medicalency.com]

Displaying restorative treatment (vitamins, diet, etc.). With a significant accumulation of fluid in the serous cavities — puncture. Periodic disease treatment (aspirin, gistoglobin, nivahin) is ineffective. [survinat.com]

Links: aetiology pathology clinical features investigations diagnosis treatment prognosis [gpnotebook.co.uk]

Some authors are of the view that it does not affect the rate of remission and survival while others relate it to a worse prognosis. [10] Cytogenetic abnormalities with poor prognosis in AML include complex karyotype, -5, del (5q), -7, del (7q), or 3q21 [ccij-online.org]

Diagnosis is one of exclusion D/D Infective consolidation Pulmonary hemorrhage Treatment: acute-steroids,immunosuppressants if steroid unresponsive chronic-asymptomatic:no treatment;poor prognosis if PFT abn Prognosis: poor; 50% mortality sequelae for [de.slideshare.net]

The prognosis depends on the underlying disease, a chronic form - to the degree of development of adhesions and violations functions of the respective bodies. Treatment is primarily the underlying disease, usually complex. [medicalency.com]

Prognosis for life is dependent on the underlying disease, and the chronic form — on the extent of adhesions and the dysfunction of the relevant authorities. Treatment of the underlying disease in the first place, as a rule, complex. [survinat.com]

Effusion analyses suggested an etiology of tuberculosis. The severe general condition of the patient allowed for no invasive diagnostic procedures. Antituberculosis therapy was administrated too late and was of no benefit. [ncbi.nlm.nih.gov]

Describes polverosa unclear etiology - the so-called periodic disease, family recurring P. [medicalency.com]

It may also facilitate prompt administration of steroids after alternate etiologies of inflammation have been ruled out. [jmedicalcasereports.biomedcentral.com]

When P. tubercular etiology on combined specific treatment streptomycin (1 g per day), Pasco (12 g), ftivazid (1.5 g). When polyserositis rheumatic etiology — antirheumatic treatment (Salicylates, antibiotics). [survinat.com]

[…] the disease is a recurrent inflammation of the serous membranes, we have designated it "recurrent polyserositis." 9 Although usually of benign nature, recurrent polyserositis is sometimes fatal because of renal failure due to amyloidosis. 10-12 The etiology [jamanetwork.com]

Epidemiologic, clinical, and pathological findings. JAMA 1980 Jul 11; 244(2):148-50. Statistics Article View: 4,008 PDF Download: 2,783 [apjmt.mums.ac.ir]

In Armenian persons (based on epidemiology among Armenian populations in Lebanon and southern California), the estimated prevalence of FMF is 1 case per 500 population, with a gene frequency of 1 per 7. [emedicine.medscape.com]

Epidemiology FMF is common in people from eastern Mediterranean countries but is not restricted to these ethnic groups. [ 5 ] Male-to-female ratio is 1.5-2:1. Presentation [ 6, 7, 8 ] The majority present in the first decade of life. [patient.info]

EPIDEMIOLOGY Prevalence influenced by age, gender, race, and genetics Prevalence: 1:2000 Peak incidence 14-45 years Black > White (1:250 vs. 1:1000) Female predominance 10:1 HLA DR3 association, Family History Severity is equal in male and female 31. [slideshare.net]

Pathophysiology Associated with mutations in the MEFV (Mediterranean fever) gene located on chromosome 16. [ 2 ] Although FMF was originally defined as an autosomal recessive disorder, approximately 10-20% of FMF patients do not carry any FMF gene (MEFV [patient.info]

The exact pathophysiology of the toxicity of this compound is not clear. After absorption through the gastrointestinal tract by simple diffusion, it is mainly excreted through kidneys and lungs. [apjmt.mums.ac.ir]

Regular administration of colchicine will prevent the attacks in 95% of patients. * * * poly·se·ro·si·tis (pol″e-sēr″o-siґtis) [ poly- + serositis ] general inflammation of serous membranes with serous effusion; see also Concato disease. [medicine.academic.ru]

Now in its second edition, this popular and essential comprehensive resource provides a detailed analysis of how to identify, prevent, and manage drug-induced diseases. Edited by James E. Tisdale and Douglas A. [books.google.de]

Treatment Colchicine is the mainstay of treatment - it is very effective, prevents attacks and helps symptoms. [patient.info]

The PCV13 vaccine is now routinely given in series with the 23-valent pneumococcal polysaccharide vaccine (PPSV23) for prevention of community-acquired pneumonia in the elderly. [jmedicalcasereports.biomedcentral.com]