Neonatal presentation: anuria palpable bladder rapidly developing renal failure First year of life presentation: failure to thrive vomiting poor stream, dribbling, incontinence often develop sepsis Diagnosis is made on micturating cystourethrography. [gpnotebook.co.uk]

Newborns may also be brought with few urinary symptoms and more non specific ones like abdominal distension, failure to thrive, signs of infection (sepsis) somewhere in the body, recurrent urinary infections with fever. [pediatriconcall.com]

If the obstruction is severe and remains unrecognized during the neonatal period, infants may present later in life with failure to thrive due to uremia or sepsis caused by infection in the obstructed urinary tract. [archintsurg.org]

The affected patients may also present with complications of the disease such as urinary tract infections, sepsis, impaired renal function, anemia, and failure to thrive. [1], [3], [4] Diagnosis of the condition may be suspected with an antenatal ultrasound [afrjpaedsurg.org]

Since boys with urethral valves have an up to 25 percent chance of kidney failure over the course of their lifetime, our specialists in Boston Children's Department of Urology make maintaining optimal bladder function the primary goal of treatment. [childrenshospital.org]

Males with PUV have about a 20% chance of developing kidney failure over their lifetime. [choc.org]

There is up to a 20% chance that kidney failure can develop over time. It is also common for boys to have problems with bladder storage and emptying such as leakage of urine or inability to completely empty the bladder. [urology.ucsf.edu]

Some children, however, maintain preserved kidney function into adulthood, whereas others develop kidney failure in childhood ( 8 ). Previous reports suggested that nadir creatinine predicts the risk of kidney failure in children with PUV. [cjasn.asnjournals.org]

Renal deterioration may also occur due to hyperfiltration injury that causes glomerulosclerosis, chronic pyelonephritis associated with vesicoureteral reflux, urinary stasis, or incomplete bladder emptying, all of which are common in boys with a posterior [emedicine.com]

The term ‘valve bladder syndrome’ was introduced as a concept in the 1980s to encompass the abnormal voiding patterns and symptoms of voiding dysfunction, the persistent thick walled bladder, incomplete bladder emptying and associated upper tract dilatation [pediatricurologybook.com]

Urinary extravasations occurred in 3 cases, significant hematuria from urethral bleeding occurred in 2, and obstructive anuria developed in 1 patient. Most of cases were treated conservatively. [ncbi.nlm.nih.gov]

Complications such as urinary retention, urinary extravasation, urethral bleeding and urethral stricture have been reported to be associated with the procedure. [6] However, these were not recorded in our patients within the period of follow-up. [afrjpaedsurg.org]