Presentation
METHOD The present report is a descriptive analytical study, carried out among patients presenting previous poliomyelitis sequelae. PPS had been diagnosed over one year earlier. [scielo.br]
It presents a broad overview of age-related physiological changes as well as specific professional discipline perspectives. [books.google.com]
When a patient with postpolio syndrome presents for surgery, special precautions are warranted, because these patients may have respiratory impairment, sleep apnea, swallowing difficulties, and cold intolerance. [ncbi.nlm.nih.gov]
When a pa-tient with postpolio syndrome presents for surgery, special precautions are warranted, because these patients may have respiratory impairment, sleep apnea, swallowing difficulties, and cold intolerance. [citeseerx.ist.psu.edu]
Entire Body System
- Fatigue
MAIN OUTCOME MEASURES: The Fatigue Severity Scale (FSS), visual analog scale (VAS) for fatigue, and Fatigue Impact Scale (FIS). [ncbi.nlm.nih.gov]
Fatigue is often the most disabling symptom; even slight exertion often produces disabling fatigue and can also intensify other symptoms. [en.wikipedia.org]
In another controlled study scientists concluded that the drug amantadine is not helpful in reducing fatigue. And other researchers recently evaluated the effectiveness of modifinil (Provigil) on reducing fatigue and found no benefit. [web.archive.org]
- Fever
If you have symptoms, they may include fever, fatigue, nausea, headache, flu-like symptoms, stiff neck and back, and pain in the limbs. A few people will become paralyzed. There is no treatment to reverse the paralysis of polio. [icdlist.com]
[…] postpericardiotomy syndrome 心膜切開[術]後症候群 postpolio syndrome ポリオ後症候群 postprandial 食後【形】 postprandial angina pectoris 食後狭心症 postprandial hypotension 食後低血圧 postprandial syncope 食後失神 postreperfusion syndrome 再灌流後症候群 postrepolarization refractoriness 再分極後不応性 postrheumatic fever [j-circ.or.jp]
The major illness associated with poliovirus often follows a mild illness, which has symptoms of fever, nausea, and vomiting. [encyclopedia.com]
This is characterized by a low grade fever and sore throat. [cdc.gov]
[…] insomnia (3%), sinusitis (6%), diarrhoea (3%), dry eyes (6%), joint or back pain (6%), headache (3%) Farbu 2007 IVIG 2g/kg body weight, 1 infusion Medication: flu‐like illness and chest myalgia (10%) Placebo: none reported Medication: chills and/or fever [doi.org]
- Chronic Fatigue Syndrome
View Article PubMed Google Scholar Packer TL, Sauriol A, Brouwer B: Fatigue secondary to chronic illness: postpolio syndrome, chronic fatigue syndrome, and multiple sclerosis. Archives of Physical Medicine & Rehabilitation. 1994, 75: 1122-1126. [bmcneurol.biomedcentral.com]
It shares many features with chronic fatigue syndrome, but, unlike that disorder, it tends to be progressive and can cause loss of muscle strength. [en.wikipedia.org]
It shares many features with the post-viral chronic fatigue syndrome, but unlike that disorder, it tends to be progressive, and as such can cause a tangible loss of muscle strength. [medicalmarijuana.com]
- Chronic Infection
Systemic conditions - eg, anaemia, chronic infection, hypothyroidism, collagen disorders, medication side-effects. Other causes of pain - eg, arthritis, bursitis, tendinopathy. Myalgias - polymyalgia rheumatica, fibromyalgia. [patient.info]
A sequence of a mutated genome in the poliomyelitis virus may be observed in the CSF of some patients; consequently, the presence of a chronic infection in infected neurons that prevails over the years is considered a mechanism. [scielo.org.co]
- Hyperthermia
Case 2 47-year-old male patient, mestizo, from Popayán (Colombia), middle class, with a history of childhood poliomyelitis at age five, who consulted the emergency service due to sensation of hyperthermia, dyspnea and oppressive chest pain. [scielo.org.co]
Respiratoric
- Pneumonia
Chewing and swallowing problems can lead to inadequate nutrition and to dehydration, as well as to aspiration pneumonia, which is caused by inhaling food particles into your lungs (aspirating). Chronic respiratory failure. [mayoclinic.org]
Weakness in swallowing muscles can result in aspiration of food and liquids into the lungs and lead to pneumonia. [web.archive.org]
Failure to properly assess PPS with respiratory involvement can increase the risk of overlooking an aspiration pneumonia (a life-threatening infection of the lower respiratory tract, especially so if not caught early on). [en.wikipedia.org]
It is possible that minor episodes of aspiration pneumonia occurred but were not symptomatic because of the ability of the lungs to clear small amounts of aspirated material. [nejm.org]
Possible left basal pneumonia was considered and management with ampicillin/sulbactam was initiated. In addition to the initial symptoms, the patient reported fatigue when walking and myalgias with weakness in the left lower limb. [scielo.org.co]
- Dyspnea
New dyspnea and other respiratory problems in those who had bulbar or upper spinal polio; some problems are so severe that the individual must return to using a respirator. Severe cold intolerance, even with mild cold exposure. [hcpro.com]
Case 2 47-year-old male patient, mestizo, from Popayán (Colombia), middle class, with a history of childhood poliomyelitis at age five, who consulted the emergency service due to sensation of hyperthermia, dyspnea and oppressive chest pain. [scielo.org.co]
The symptoms of dyspnea, daily hypersomnolence, insomnia and new weakness were more frequent in patients with CAH than in patients with OSAS. [scielo.br]
Cardiovascular
- Chest Pain
pain 梗塞後胸痛 postinfarction counseling 梗塞後カウンセリング postinfarction depression 梗塞後うつ病(状態) postinfarction management 梗塞後処置治療 postinfarction myocardial ischemia 梗塞後心筋虚血 postinfarction syndrome 梗塞後症候群 postinfarction ventricular aneurysm 梗塞後心室瘤 postinfarction [j-circ.or.jp]
If you or someone in your care has chest pains, difficulty breathing, or severe bleeding, it could be a life-threatening emergency. Call 9-1-1 or the local emergency number immediately. [healthlinkbc.ca]
Case 2 47-year-old male patient, mestizo, from Popayán (Colombia), middle class, with a history of childhood poliomyelitis at age five, who consulted the emergency service due to sensation of hyperthermia, dyspnea and oppressive chest pain. [scielo.org.co]
[…] muscle and gastrointestinal cramp and 5. nausea, diarrhoea, vomiting and faintness) Placebo: 1 patient (2%) angina, shortness of breath Medication: 7 patients (11%) muscle cramps, abdominal pain, nausea, diarrhoea, profuse sweating, chest pain, fractured [doi.org]
Eyes
- Foreign Body Sensation
On admission to the emergency service, a foreign body sensation was reported in the right dorsal region, possibly associated with the history of arthrodesis. Source: Document obtained during the study. [scielo.org.co]
Musculoskeletal
- Muscle Weakness
The symptoms are new muscle weakness, decreased muscle endurance, fatigue, muscle pain, joint pain, cold intolerance, and this typical clinical entity is reported from different parts of the world. [doi.org]
weakness or abnormal muscle fatigability (decreased endurance), with or without generalized fatigue, muscle atrophy, or muscle and joint pain. [web.archive.org]
- Muscular Atrophy
The rate of progression of post-poliomyelitis muscular atrophy is quite variable. [nejm.org]
The symptoms and signs of PPS include new muscle weakness and atrophy (post-poliomyelitis progressive muscular atrophy; PPMA),as well as other musculoskeletal symptoms such as fatigue, skeletal deformity, and pain. [ci.nii.ac.jp]
G12.29 Other motor neuron disease G12.8 Other spinal muscular atrophies and related syndromes G12.9 Spinal muscular atrophy, unspecified G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere G13.0 Paraneoplastic [icd10data.com]
This muscle weakness may or may not be accompanied by fatigue, myalgia, muscular atrophy and subsequent loss of functionality. If electromyographic changes are seen, we can see that is truly a post-polio syndrome (Halstead's criteria). [guttmann.com]
- Myopathy
Part two then addresses the complete range of specific neuromuscular diseases: neuronopathies, peripheral neuropathies, neuromuscular junction disorders, muscle ion channel disorders, myopathies, and miscellaneous neuromuscular disorders and syndromes [books.google.com]
A history of more rapid progression of muscle weakness during weeks or months could indicate an alternative diagnosis, such as myopathy (e.g., polymyositis, thyroid myopathy), peripheral nerve disorders, or motor neuron disorder (e.g., amyotrophic lateral [clinicalgate.com]
[…] poliomyelitis and post-poliomyelitis syndrome: Other neurologic syndromes that may be confused with poliomyelitis or PPS include ALS, Guillain-Barre syndrome, West Nile virus, other non-polio enteroviruses, diphtheria, botulism, radiculopathy, neuropathy, and myopathy [clinicaladvisor.com]
The neurological deterioration and functional decline of post-polio syndrome may be related to normal aging, overuse myopathy and disuse. [now.aapmr.org]
Post polio syndrome, spinal cord injury and statin myopathy: double trouble or incorrect diagnosis? Two case reports. J Rehabil Med 2011; 43:734-735. 4. Gunnar G, Jianan Li, Carol V, M. Elizabeth S. [jpma.org.pk]
- Myalgia
This muscle weakness may or may not be accompanied by fatigue, myalgia, muscular atrophy and subsequent loss of functionality. If electromyographic changes are seen, we can see that is truly a post-polio syndrome (Halstead's criteria). [guttmann.com]
Record Dates Last Update Posted: November 17, 2015 Last Verified: November 2015 Keywords provided by Biolab Sanus Farmaceutica: Postpoliomyelitis Syndrome Piracetam L-Carnitine Additional relevant MeSH terms: Layout table for MeSH terms Syndrome Fatigue Myalgia [clinicaltrials.gov]
In addition to the initial symptoms, the patient reported fatigue when walking and myalgias with weakness in the left lower limb. [scielo.org.co]
Myalgias - polymyalgia rheumatica, fibromyalgia. Management [ 4 ] Editor's note August 2018 - Dr Hayley Willacy recommends the guide to management of post-polio syndrome for healthcare professionals [ 11 ]. [patient.info]
[…] respiratory problems (14%) Placebo: cold virus (6%), heartburn (6%), insomnia (3%), sinusitis (6%), diarrhoea (3%), dry eyes (6%), joint or back pain (6%), headache (3%) Farbu 2007 IVIG 2g/kg body weight, 1 infusion Medication: flu‐like illness and chest myalgia [doi.org]
- Muscle Cramp
However, at the age of 48, he developed left sided lower limb weakness, generalized aches and pains and muscle cramps. These symptoms have been progressively worsening for past 2 years. [jpma.org.pk]
[…] and gastrointestinal cramp and 5. nausea, diarrhoea, vomiting and faintness) Placebo: 1 patient (2%) angina, shortness of breath Medication: 7 patients (11%) muscle cramps, abdominal pain, nausea, diarrhoea, profuse sweating, chest pain, fractured fibula [doi.org]
These late symptoms are referred to as Postpoliomyelitis Syndrome (PPS) and include new or increased muscle weakness, abnormal muscle fatigability, generalized fatigue, muscle atrophy, muscle and joint pain, muscle cramps and cold intolerance [ 1 ]. [bmcneurol.biomedcentral.com]
Psychiatrical
- Suggestibility
Although the cause of PPMA is unknown, electrophysiological (SFEMG) and muscle biopsy studies suggest that the process involves a loss or dropout of axon terminals of reinnervated motor units. [ncbi.nlm.nih.gov]
The NCV findings are also suggestive of Right Tarsal tunnel syndrome Conclusion Study was suggestive of ongoing axonal degeneration in right deltoid, biceps, and bilateral soleus muscles with regeneration with new symptoms of weakness and fatigue. [mjdrdypu.org]
However, intracellular pH and phosphocreatine were not different in the two groups at rest or during exercise or recovery, suggesting that the greater fatigue of the patients was not due to an excessive change of metabolites. [neurology.org]
- Anxiety Disorder
References Introduction Epidemiology Challenges in Geriatric Psychiatry WorkUp Depression Bereavement Schizophrenia Cognitive Disorders Substance Abuse Anxiety Disorders Geriatric Psychiatry Emergencies Special Populations in Geriatric Psychiatry Palliative [books.google.com]
Neurologic
- Stroke
Get a broader perspective on your field from new chapters on Labral Tears of the Shoulder and Hip, Pubalgia, Chondral Injuries, Central Post-Stroke Pain (Thalamic Pain Syndrome), Chemotherapy-induced Peripheral Neuropathy, Radiation Fibrosis Syndrome, [books.google.com]
Author Affiliations From the National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, Md. Address reprint requests to Dr. Dalakas at Bldg. 36, Rm. 5D06, NIH, NINCDS, Bethesda, MD 20892. [doi.org]
The United States National Institute of Neurological Disorders and Stroke (NINDS) lists the following Criteria for diagnosis of post-polio syndrome * Prior paralytic poliomyelitis with evidence of motor neuron loss, as confirmed by history of the acute [post-polio.org]
Between 2 and 4 out of 10 adults who had polio may get post-polio syndrome. footnote 1 References Citations National Institute of Neurological Disorders and Stroke (2012). Post-Polio Syndrome Fact Sheet. (NIH Publication No. 12-4030). [healthlinkbc.ca]
However, it is not usually useful for diagnosis. 13 Scientists from the National Institute of Neurological Disorders and Stroke (NINDS) and other institutions have shown, through several studies, that the weakness caused by PPS is a slow-evolving condition [scielo.org.co]
- Radiculopathy
Absence of sensory affection and absence of pain on examination ruled out brachial neuritis and cervical radiculopathy. Furthermore on examination, there was no neck pain and no provocative tests positive for cervical radiculopathy. [mjdrdypu.org]
The findings allowed ruling out radiculopathy and compressive neuropathy. Source: Document obtained during the study. Figure 2 Electromyogram report. [scielo.org.co]
[…] diseases that mimic poliomyelitis and post-poliomyelitis syndrome: Other neurologic syndromes that may be confused with poliomyelitis or PPS include ALS, Guillain-Barre syndrome, West Nile virus, other non-polio enteroviruses, diphtheria, botulism, radiculopathy [clinicaladvisor.com]
Secondary radiculopathies and compression neuropathies are common. Respiratory muscle weakness may result in restrictive pulmonary disease or sleep apnea. 2. [now.aapmr.org]
It can also help to identify and exclude other conditions like radiculopathy, neuropathy and myopathy. 9 However, it cannot alone differentiate between PPS and asymptomatic patients with previous poliomyelitis. [jpma.org.pk]
Workup
There is no diagnostic test for PPS, and the diagnosis is based on a proper clinical workup where all other possible explanations for the new symptoms are ruled out. [ncbi.nlm.nih.gov]
ADLs Inability to Initiate Meaningful Activities Anxiety Spatial Disorientation Rejection of Care Food Refusal Insomnia Apathy and Agitation Elopement and Interference with Others References Introduction Epidemiology Challenges in Geriatric Psychiatry WorkUp [books.google.com]
The prevalence of PPS has been reported to be between 20% and 85% of people who have had poliomyelitis. [2] There is no diagnostic test for PPS, and the diagnosis is based on a proper clinical workup where all other possible explanations for the new symptoms [mjdrdypu.org]
Treatment
The effectiveness of pharmacological treatment and rehabilitation management in PPS is not yet established. Objectives To review systematically the effects of any treatment for PPS compared to placebo, usual care or no treatment. [doi.org]
The effectiveness of pharmacological treatment and rehabilitation management in PPS is not yet established. To review systematically the effects of any treatment for PPS compared to placebo, usual care or no treatment. [ncbi.nlm.nih.gov]
The objective of this review was to assess the benefits and harms of different drugs and rehabilitation treatments compared to placebo (a pill or procedure without any physiological effect), usual care or no treatment. [cochrane.org]
Physical Therapy Surgery References Introduction Effects of Ageing and Related Diseases on Endocrine Diseases The Hormonal Fountain of Youth References Introduction Water Homeostasis in the Elderly Workup and Treatment of Hyponatraemia Workup and Treatment [books.google.com]
Prognosis
When unilateral, the prognosis is good, but bilateral diaphragmatic paralysis often has a worse prognosis. • Supportive care, self-selected life style changes, and energy conservation strategies still remain the main axiom of therapy. • Post-polio patients [medlink.com]
Prognosis Prognosis for patients with post polio syndrome is relatively good. It is a very slow, gradually progressing syndrome. Only about 20% of all patients with PPS will need to rely on new aids for mobility or breathing. [encyclopedia.com]
The prognosis also differs depending upon different causes and factors affecting the individual. [en.wikipedia.org]
Treatment can improve both quality of life and prognosis. Aetiology Respiratory problems in PPS may be due to one or more of: Respiratory muscle weakness. Bulbar impairment - this may affect control of the upper airway or the respiratory cycle. [patient.info]
Differential diagnosis and prognosis. In: Halstead LS, Grimby G, eds. Post-polio syndrome. Philadelphia: Hanley & Belfus, 1995, pp. 69-88. Google Scholar 9. Gawne AC. Strategies for exercise prescription in post-polio patients. [link.springer.com]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
We review possible etiologies of laryngeal PPS, diagnostic criteria, and treatment, as well as the current literature. [ncbi.nlm.nih.gov]
[…] time in various reports from the acute poliomyelitis until the onset of PPS is about 35 years, with a range from 8 to 71 years. 1 However, it is unclear if the occurrence of PPS increases with aging, which may be the case based on the most accepted etiologic [doi.org]
[…] postpoliomyelitis syndrome [ pōst-po″le-o-mi-ĕ-li´tis ] a group of symptoms of unknown etiology seen in patients several years to many years after they have recovered from the major illness of poliomyelitis ; it includes new weakness, fatigue, and pain [medical-dictionary.thefreedictionary.com]
Epidemiology
Ramlow, Epidemiology Department, Dow Chemical Co., 1803 Building, Midland, MI 48674 Search for other works by this author on: Jonathan Ramlow 2 Alfred I. [doi.org]
Homes Successful Ageing Future Research Introduction Developments in the UK 20052010 Services Patients Views and Involvement Additional Responsibilities for Geriatric Psychiatry Services Other Issues An International Perspective References Introduction Epidemiology [books.google.com]
Epidemiology of the post-polio syndrome. Am J Epidemiol. 1992 Oct 1. 136(7):769-86. [Medline]. Quadros AA, Conde MT, Marin LF, Silva HC, Silva TM, Paula MB, et al. [emedicine.medscape.com]
Pathophysiology
The pathophysiology behind PPS is not fully understood, but a combination of distal degeneration of enlarged motor units caused by increased metabolic demands and the normal aging process, in addition to inflammatory mechanisms, are thought to be involved [ncbi.nlm.nih.gov]
[…] of the Ageing Bladder Special Disease States Pharmacology as it Relates to the Ageing Bladder Surgical Disease of the Ageing Bladder Conclusion References Introduction Benign Prostatic Hyperplasia Prostate Cancer Prostatitis References Introduction Pathophysiology [books.google.com]
Prevention
Centers for Disease Control and Prevention Polio: Information for Parents (American Academy of Family Physicians) Polio: Information for Parents (American Academy of Pediatrics) Polio: Information for Parents (Centers for Disease Control and Prevention [icdlist.com]
Aging with Polio and Preventing Secondary Disability 13. Energy Conservation and Pacing 14. Gait, Bracing, Shoes and Assistive Devices 15. Motorized mobility 16. Complimentary and Alternative Medicine 17. [elsevier.com]
CONCLUSIONS: These findings suggest that work-oriented interventions aimed at preventing PPS patients from dropping out of the workforce should primarily focus on reducing physical job demands, arranging adaptations in the workplace and increasing job [ncbi.nlm.nih.gov]
[…] avoided through preventive measures. [now.aapmr.org]