Presentation
In the present trial, either three or nine courses of this combination were given to previously untreated patients with advanced breast cancer. [ncbi.nlm.nih.gov]
Immune System
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Inguinal Lymphadenopathy
A 79-year-old woman presented with weight loss, night sweats, asthenia, bilateral inguinal lymphadenopathy, and splenomegaly. [doi.org]
Cardiovascular
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Thrombosis
Erythropoietin The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Prednimustine. [drugbank.ca]
Skin
Musculoskeletal
Psychiatrical
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Suggestibility
It is suggested that prednisolone plasma levels are as good a parameter of Prednimustine absorption and bioavailability as chlorambucil levels, Prednimustine itself having never been detected in plasma. [ncbi.nlm.nih.gov]
The mortality figures suggested that prednimustine was considerably less toxic than equipotent doses of C P. This toxicity difference was confirmed in a parallel investigation of the subacute toxicity in rats of prednimustine and C P. [onlinelibrary.wiley.com]
Neurologic
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Encephalopathy
2 ) [letter] ( 3 ) Prednimustine-induced myoclonus—a report of three cases, Acta Oncol, 1944, vol. 33 (pg. 81 - 2 ) ( 4 ) Myoclonus and mitochondrial myopathy, Adv Neurol, 1986, vol. 43 (pg. 105 - 17 ) ( 5 ) Prophylaxis and reversal of ifosfamide encephalopathy [doi.org]
Workup
Cerebrospinal fluid analysis in the workup of GLUT1 deficiency syndrome: a systematic review. JAMA Neurol. 70, 1440–1444 (2013). 75. Nie, S., Chen, G., Cao, X. & Zhang, Y. [nature.com]
Serum
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Lymphopenia
[…] squamous-cell carcinomas of the external auditory canal. 5.3 Human carcinogenicity data No data were available to the Working Group. 5.4 Other relevant data In humans, prednimustine causes leukopenia and thrombocytopenia; in experimental animals, it causes lymphopenia [inchem.org]
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Erythroblast
Languages: eng Pagination: 388-92 Citation Subset: IM Export Citation: APA/MLA Format Download EndNote Download BibTex MeSH Terms Descriptor/Qualifier: Adult Aged Chlorambucil / analogs & derivatives* Clinical Trials as Topic Female Humans Leukemia, Erythroblastic [biomedsearch.com]
Treatment
PURPOSE: To evaluate prospectively in patients with follicular lymphoma and a low tumor burden three therapeutic options: delay of any treatment until clinically meaningful progression, immediate treatment with an oral alkylating agent, or treatment with [ncbi.nlm.nih.gov]
Prognosis
For others, because delay of treatment until significant clinical progression does not seem to hamper the prognosis or subsequent response to treatment, the long-term toxicity of alkylating agents can be reduced. [ncbi.nlm.nih.gov]
In the 1990s, additional high-dose chemotherapy with autologous stem-cell transplantation (SCT) was introduced for patients with unfavorable prognosis. [bocsci.com]
Epidemiology
In Vitro Models and Animal 486 The Evaluation of Chemotherapy in a Murine 495 Epidemiology of Renal Tumors 503 Unrecognized Renal Cell Carcinoma 509 Circulation Time and Renal Blood Flow 519 Hormone Therapy and Receptor Studies in Renal 527 Diagnosis [books.google.de]
Pathophysiology
An overview of its clinical features, pathophysiological mechanisms, and management. Neurophysiol. Clin. 36, 337–343 (2006). 18. Spiro, A. J. Minipolymyoclonus: a neglected sign in childhood spinal muscular atrophy. [nature.com]
Prevention
Drug / Medicine - Used to treat, alleviate, cure or prevent sickness. [1source.com]
Supplements intracellular folate supply, resulting in inhibition of thymidylate synthesis (TS) Antibiotics [ edit ] Anthracyclines [ edit ] Antitumor antibiotics, produced by Streptomyces soil fungus Mechanism: Intercalate between DNA base pairs and prevent [en.wikibooks.org]
And you can take steps to help prevent infections. Side effects generally are short-term problems. They gradually go away during the recovery part of the chemo cycle or after the treatment is over. Fatigue is a common side effect of chemotherapy. [northshore.org]