Dysgenesis Ace renovascular hypertension Ace Reperfusion Injury Ace, Klk1, Serping1 respiratory system disease Ace rheumatoid arthritis A2m, Bdkrb2 rhinitis Bdkrb1, Bdkrb2 Right Ventricular Hypertrophy Ace sarcoidosis Ace sciatic neuropathy Bdkrb1, Bdkrb2 Sepsis [rgd.mcw.edu]

DIC • an attempt to correct any reversible cause of DIC; (2) measures to control the major symptom, either bleeding or thrombosis; and (3) a prophylactic regimen to prevent recurrence in cases of chronic DIC. • abruptio placentae or acute bacterial sepsis [slideshare.net]

Congenital infection, sepsis, significant metabolic disorders (such as tyrosinaemia) and Kasabach‐Merritt syndrome [ 4 ] are a few of the many conditions that need to be considered. [onlinelibrary.wiley.com]

[…] decrease gut flora), malabsorption/malnutrition (vit K is fat-soluble) and Warfarin therapy 1. disseminated intravascular coagulation 2. acquired syndrome characterized by intravascular activation of coagulation 3. causes include - endotoxin causing sepsis [brainscape.com]

The emphasis is placed on identification of patients with a potential bleeding problem and management of these patients if surgical procedures are needed. [pocketdentistry.com]

procedures [ 35 ]. [onlinelibrary.wiley.com]

DDAVP also has been effectively used as a prophylactic agent in preparation for elective surgical procedures in patients with mild hemophilia A and vWD. 29,31,33 If used as a prophylactic agent to prevent surgical bleeding, it is suggested that an infusion [ahcmedia.com]

Reperfusion Injury Serping1 Splenomegaly Bdkrb1 Spontaneous Abortion F12 Staphylococcal Infections Ace Stomach Neoplasms Ace Stroke Ace, F12, Kng2 substance-induced psychosis Ace Sudden Death Ace Sudden Death, Cardiac Kng2 syndromic X-linked intellectual disability [rgd.mcw.edu]

KDM6A Xp11.3 Kabuki syndrome 2 300867 300128 X-linked dominant KHK 2p23.3 [Fructosuria] 229800 614058 Autosomal recessive KIAA0319 6p22.3 {Dyslexia, susceptibility to, 2} 600202 609269 Autosomal dominant KIDINS220 2p25.1 Spastic paraplegia, intellectual disability [mnglabs.com]

[…] external ophthalmoplegia POLG Parkinson disease, early-onset POLG SANDO POLG Progressive external ophthalmoplegia POLG2 Xeroderma pigmentosum, variant POLH Obesity, adrenal insufficiency and red hair POMC Obesity POMC Muscle-eye-brain disease POMGNT1 Motor disability [springer.com]

heart failure Ace coronary artery disease Ace Coronary Disease Ace, F12 coronary restenosis Ace Coronavirus Infections Ace Cough Ace, Bdkrb2, Kng2 Death F12 Diabetes Complications Bdkrb1, Bdkrb2 Diabetes Mellitus, Experimental Ace, Bdkrb1, Bdkrb2, Klk1 [rgd.mcw.edu]

heart failure Paroxysmal nocturnal hemoglobinuria Physiologic states Pregnancy ( especially postpartum ) Obesity Postoperative state Immobilization Old age DISORDERS OF PLATELET AND VESSEL WALL • usually bleed into superficial sites such as the skin, [slideshare.net]

These digestive problems can lead to failure to thrive and malnutrition. Most affected children are better able to tolerate sucrose and maltose as they get older. [resourcerepository.org]

[…] production of the vitamin K dependent factors - II, VII, IX, X, protein C and protein s 3. vitamin K deficiency can be caused by hemorrhagic disease of the newborn (newborns do not have functioning vit K), antibiotics (decrease gut flora), malabsorption/malnutrition [brainscape.com]

Jeffrey Weitz, Professor of Medicine at McMaster University School of Medicine and Executive Director of the Thrombosis and Atherosclerosis Research Institute in Ontario. [books.google.com]

[…] deficiency. ( 3487556 ) Bouma BN...Griffin JH 1986 30 Prekallikrein deficiency in a dog. ( 3632973 ) Chinn DR...Selcer BA 1986 31 Prekallikrein deficiency in a family of miniature horses. ( 3641551 ) Turrentine MA...Johnson GS 1986 32 Multiple cerebral thrombosis [malacards.org]

(PMID: 19583818) Li Y … Rosendaal FR (Journal of thrombosis and haemostasis : JTH 2009) 3 22 45 60 Common variation in KLKB1 and essential hypertension risk: tagging-SNP haplotype analysis in a case-control study. [genecards.org]

[…] is more common 5. thrombosis is likely due to platelet aggregation and activation of coagulation 6. symptoms include thrombocytopenia, thrombosis, and allergic reactions 1. due to congenital X-linked recessive deficiency of Factor VIII 2. results in [brainscape.com]

BLEEDING AND THROMBOSIS ! Vessel wall, blood platelets and plasma proteins ! Normal hemostatic system balance between thrombosis and bleeding ! [slideshare.net]

Lemmens J. 2016 6 Prekallikrein deficiency. ( 27585864 ) Zheng S....Brighton T. 2016 7 A comparison of the effects of factor XII deficiency and prekallikrein deficiency on thrombus formation. ( 26950760 ) Kokoye Y....Gailani D. 2016 8 Prevalence of hypertension [malacards.org]

(PMID: 19583818) Li Y … Rosendaal FR (Journal of thrombosis and haemostasis : JTH 2009) 3 22 45 60 Common variation in KLKB1 and essential hypertension risk: tagging-SNP haplotype analysis in a case-control study. [genecards.org]

Ace, Bdkrb1, Bdkrb2, F12, Klk1, Klkb1, Kng2 Hypertension, Pregnancy-Induced Ace Hypertensive Nephrosclerosis Ace hypertrophic cardiomyopathy Ace Hypoalbuminemia A2m Hypophosphatemic Nephrolithiasis/Osteoporosis F12 Hypotension Ace, Bdkrb2, Kng2 IgA glomerulonephritis [rgd.mcw.edu]

Labs: increased 17OH pregenterone Classic 11OHase deficiency Salt retention/hypertension (11-deoxycorticosterone), increased 17KS (virilization), skin hyperpigmentation Salt retention, hypertension, (aldosterone), female hypogonadism (decreased 17KS), [cram.com]

We check for diseases such as: Alzheimer’s disease Asthma Breast cancer Colorectal cancer Cystic Fibrosis Diabetes Hypertension Leukemia Lung cancer Multiple sclerosis Myocardial infarction Obesity Osteoarthritis Parkinson’s disease Prostate cancer Skin [21gfox.ca]

Hematologic disease Brite Human diseases [BR: br08402 ] Cardiovascular diseases Hematologic diseases H01078 Fletcher factor deficiency Human diseases in ICD-11 classification [BR: br08403 ] 03 Diseases of the blood or blood-forming organs Coagulation defects, purpura [genome.jp]

It is defined as the combination of a plasma-cell proliferative disorder (typically myeloma), polyneuropathy, and effects on many othe … Thrombotic Thrombocytopenic Purpura Thrombotic thrombocytopenic purpura (TTP or Moschcowitz syndrome[1]:822) is a [checkrare.com]

50,000 - 100,000 "mild prolonged BT ; 50,000 " easy bruising, purpura, mucosal bleeding, 20,000 " spontaneous bleeding, internal or intracranial bleed ! [slideshare.net]

1. immune thrombocytpenic purpura 2. thrombotic thrombocytopenic purpura 3. hemolytic uremic syndrome 4. heparin induced thrombocytopenia 1. immune thrombocytopenic purpura 2. caused by antibodies to platelet antigens 3. antigenic target varies - GPIIb [brainscape.com]

[…] chronic aseptic meningitis, mental retardation, headache lymphatic splenomegaly, occasional lymphadenopathy splenomegaly, occasional lymphadenopathy cervical adenopathy in children not seen rare hepatosplenomegaly, adenopathy vasculitis Henoch-Schonlein purpura [ufrgs.br]

A few people with prekallikrein deficiency have experienced health problems related to blood clotting such as heart attack, stroke, a clot in the deep veins of the arms or legs ( deep vein thrombosis ), nosebleeds, or excessive bleeding after surgery. [ghr.nlm.nih.gov]

The condition is usually discovered when blood tests are done for other reasons.A few people with prekallikrein deficiency have experienced health problems related to blood clotting such as heart attack, stroke, a clot in the deep veins of the arms or [ncbi.nlm.nih.gov]

Bdkrb1, Bdkrb2 Sepsis A2m, Klkb1 severe acute respiratory syndrome Ace Shock, Traumatic Serping1 silicosis Cpm Skeletal Muscle Reperfusion Injury Serping1 Splenomegaly Bdkrb1 Spontaneous Abortion F12 Staphylococcal Infections Ace Stomach Neoplasms Ace Stroke [rgd.mcw.edu]

White thrombi : arteries ; high blood flow ; rich in platelets ; little fibrin ; emboli " occlusion of arteries like TIA and Stroke ( cerebral arteries ), 6. [slideshare.net]