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Prepyloric Ulcer


Presentation

  • All patients presenting with active DU should therefore be investigated for evidence of previous prepyloric ulceration.[ncbi.nlm.nih.gov]
  • In one third of patients, the presentation is less obvious, resulting in significant delays in diagnosis of peritonitis.[aclr.com.es]
  • We present a case report of a 48-year-old woman with intractable prepyloric ulcers treated with laparoscopic bilateral truncal vagotomy, antrectomy, and Billroth I anastomosis.[ncbi.nlm.nih.gov]
  • This site is presented for educational and general informational purposes only. It does not purport to offer medical advice for any specific medical condition or individual patient.[endoatlas.com]
  • Fifty-three patients presented with GU, two with PPU and two with both types of ulcer. The maximum ulcer diameter was 5-10 mm in 27 patients and greater than 10 mm in 30 patients.[ncbi.nlm.nih.gov]
Weight Loss
  • Consequently, people can experience symptoms of increased fatigue or weight loss, the UMMC reports. Weight loss is typically accompanied by a diminished appetite, and can exacerbate feelings of weakness or tiredness. Lose Weight. Feel Great![livestrong.com]
  • Additional signs indicating complications include dizziness, clammy skin, nausea, weight loss and severe pain. Lose Weight. Feel Great! Change your life with MyPlate by LIVE STRONG .COM[livestrong.com]
  • Systemic Weight loss Anaemia if dripping Complications Bleed - malaena or haematemesis Perforation Gastric outflow obstruction - suspect if vomiting, esp if old food/ copious/ persistent.[gog.net.nz]
  • Other symptoms may include: Bloated feeling Burping Lack of appetite or weight loss Nausea Bloody or dark poop Vomiting Small ulcers may not cause any symptoms. But if you notice any of these signs, talk to your doctor.[webmd.com]
  • On occasion, the dysphagia can be severe enough to cause debilitation and significant weight loss. Chronic aspiration and repetitive respiratory infection are common associated complaints.[quizlet.com]
Splenectomy
  • […] and Splenorrhaphy 409 Laparoscopic Splenectomy 420 The Liver Biliary Tract and Pancreas 425 Cholecystectomy Common Bile Duct Exploration and Liver Biopsy 426[books.google.ro]
  • Hone and expand your surgical skills by watching videos of minimally invasive procedures for recto urethral fistula, biliary atresia, laparoscopic splenectomy, uterine horn, and more.[books.google.com]
Vomiting
  • This text then discusses the general symptoms of dyspepsia, including discomfort, pain, heartburn, flatulence, acid eructation, nausea, vomiting, and visceral tenderness.[books.google.com]
  • Prepyloric Ulcer 56 year-old man with hematemesis (vomiting blood) and melena (black, tarry stools). Endoscopy revealed this 1 cm prepyloric ulcer, which was no longer bleeding.[endoatlas.com]
  • If an antral ulcer begins to bleed, people can notice blood in their stools or vomit. Blood in the digestive tract can cause stools to appear tar-like or black, while vomit can resemble coffee grounds, the New York Langone Medical Center warns.[livestrong.com]
  • Less often, ulcers may cause severe signs or symptoms such as: Vomiting or vomiting blood — which may appear red or black Dark blood in stools, or stools that are black or tarry Trouble breathing Feeling faint Nausea or vomiting Unexplained weight loss[mayoclinic.org]
Nausea
  • This text then discusses the general symptoms of dyspepsia, including discomfort, pain, heartburn, flatulence, acid eructation, nausea, vomiting, and visceral tenderness.[books.google.com]
  • Case report A 19-year-old man presented to the emergency department with a history of abdominal pain, nausea and anorexia from 4- days ago. Abdominal pain was periodic during this period.[aclr.com.es]
  • […] upper GI bleeding Type 1 (along lesser curvature of stomach) Type 2 (two ulcers, one gastric and the other duodenal) Type 3 (pre-pyloric ulcer) Type 4 (proximal gastroesophageal ulcer) Type 5 (anywhere) History / PE : Melena Abdominal pain Hematemesis Nausea[medlibes.com]
  • Symptoms Burning stomach pain Feeling of fullness, bloating or belching Fatty food intolerance Heartburn Nausea The most common peptic ulcer symptom is burning stomach pain. Stomach acid makes the pain worse, as does having an empty stomach.[mayoclinic.org]
Epigastric Pain
  • Abstract A 77 years old man had a sudden onset of an epigastric pain and melena in the course of acute respiratory failure.[jlc.jst.go.jp]
  • In past medical history, the patient had significant history of epigastric pain from the last 12-months without diagnostic evaluation for its cause. He has no history of smoking or drinking alcohol. Drug history was negative.[aclr.com.es]
  • Efferent loop syndrome is associated with epigastric pain, distension, and bilious vomiting; operation is the treatment of choice.[gastrotraining.com]
  • The player requires Flash Player plugin Case description This 42 year-old female, who presented severe epigastric pain. A small ulcer is observed at the anterior wall, giving the sensation that this ulcer has been divided in two Satellite ulcers.[medtube.net]
  • Clinical Features and Natural History Top The leading symptom is epigastric pain or epigastric discomfort.[empendium.com]
Early Satiety
  • Early satietyearly satiety may be due to gastric stasis or resection. Symptoms consist of epigastric fullness with meals, often followed by emesis. Small and frequent meals help besides prokinetic agents.[gastrotraining.com]
  • Patients may present with early satiety, nausea, vomiting of undigested food, and weight loss.[emedmd.com]
Eructation
  • This text then discusses the general symptoms of dyspepsia, including discomfort, pain, heartburn, flatulence, acid eructation, nausea, vomiting, and visceral tenderness.[books.google.com]
Venous Insufficiency
  • Venous stasis ulcers occur as a result of venous insufficiency in the lower limb. The insufficiency is due to deep vein thrombosis and failure of the one-way valves that act during muscle contraction to prevent the backflow of blood.[medical-dictionary.thefreedictionary.com]

Workup

  • However, the presence of hypercalcemia in a patient with ZES should prompt a workup for MEN1 (multiple endocrine neoplasia type 1). In MEN1 patients, the organ most involved is the parathyroid.[quizlet.com]
  • CT workup and en-bloc resection if an occult or obvious malignancy is present. Complications of Surgery Early Duodenal stump leakage, gastric retention, haemorrhage in post-operative period.[gog.net.nz]
Hemophilus Ducreyi
  • Ulcerative colitis 溃疡性结肠炎 A soft,highly infectious,nonsyphilitic venereal ulcer of the genital region,caused by the bacillus Hemophilus ducreyi.[hujiang.com]

Treatment

  • We conclude that a daily dose of 300 mg ranitidine is superior to 200 mg ranitidine in the treatment of duodenal and prepyloric ulcer and that the short-term use of ranitidine seems to be safe for the treatment of these ulcers.[ncbi.nlm.nih.gov]
  • A 6-month follow-up study revealed no significant difference between the recurrence rates after omeprazole or after cimetidine treatment.[ncbi.nlm.nih.gov]
  • Sucralfate is safe and as effective as cimetidine in the short-term treatment of prepyloric ulcer.[ncbi.nlm.nih.gov]
  • Consequently, sucralfate represents as effective and safe treatment for duodenal ulcer.[ncbi.nlm.nih.gov]
  • Few side effects and a comparatively low recurrence rate makes PCV the method of choice in the surgical treatment of peptic ulcer disease.[ncbi.nlm.nih.gov]

Prognosis

  • Treatment and prognosis Treatment depends on the clinical presentation.[radiopaedia.org]
  • Waquaruddin Ahmed, Huma Qureshi, Syed Ejaz Alarn, Sarwar Jehan Zuberi ( PMRC Research Centre, Jinnah Postgraduate Medical Centre, Karachi-35. ) ABSTRACT Retrospective analysis of 115 cases of perforated duodenal ulcer was done to determine the long term prognosis[jpma.org.pk]
  • . - if hard to distinguish, better prognosis if Ca -- 50-75% cure chance. Biopsy should be taken at the same time for H pylori. - Ideally 7 bx (10 good) and brush biopsy. - False ve rare, false -ve in 5-10%.[gog.net.nz]
  • The poor prognosis of gastric cancer also makes ascertainment bias an unlikely explanation.[nejm.org]

Etiology

  • The etiological factors responsible for peptic perforation vary depending upon sociodemographic factors [ 8 - 10 ].[aclr.com.es]
  • The etiology is still unclear but previous surgical interventions, such as antireflux procedures or partial gastrectomies, have been recognized as a known risk factor.[wjes.biomedcentral.com]
  • Burge H: The etiology of benign lower curve gastric ulcer: Vagotomy and pyloroplasty in its treatment. Ann R Coll Surg 38:349–369, 1966 Google Scholar 22. Dragstedt LR, Woodward ER: Gastric stasis, a cause of gastric ulcer.[link.springer.com]
  • This is the most common etiology of type 3 ulcers, or prepyloric ulcers. Further Reading Peptic Ulcer - What are Peptic Ulcers? Peptic Ulcer Symptoms Peptic Ulcer Diagnosis Living with Peptic Ulcer Disease Peptic Ulcer Treatments[news-medical.net]
  • Definition, Etiology, Pathogenesis Top Peptic ulcer disease ( PUD ) is a recurring formation of gastric and/or duodenal peptic ulcers.[empendium.com]

Epidemiology

  • Dig Surg 27: 161-169 Lau JY, Sung J, Hill C, Henderson C, Howden CW, et al. (2011) Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion 84: 102-113.[aclr.com.es]
  • Kurata JH, Haile BM: Epidemiology of peptic ulcer disease. Clin Gastroenterol 13:289–307, 1984 Google Scholar 2. Thomas JM, Misiewicz G: Histamine H 2 -receptor antagonists in the short- and long-term treatment of duodenal ulcers.[link.springer.com]
  • -E.H.); the Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md. (A.W.H., J.F.F.); the International Epidemiology Institute, Rockville, Md. (W.[nejm.org]
  • Methods Statistics Trigonometry Medical & Nursing Anatomy Anesthesiology Audiology Bacteriology Biochemistry Bioethics Biomedical Science Cardiology Cardiovascular Childbirth Chiropractic Dentistry Dermatology Diagnostic Imaging Drugs Endocrinology Epidemiology[brainscape.com]
  • Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion. 2011;84(2):102-13. doi: 10.1159/000323958. Review. PubMed PMID: 21494041.[empendium.com]
Sex distribution
Age distribution

Pathophysiology

  • A second outstanding feature of this volume is its success in balanc ing basic pathophysiology with practical considerations of clinical man agement.[books.google.com]
  • New insights into the pathophysiology of the disease resulted from these developments and revived the scientific interest in peptic ulcer disease.[books.google.com]
  • Gastrointestinal Surgery: Pathophysiology and Management is an invaluable reference text for surgeons and surgical trainees. Written entirely by Dr. Haile T.[books.google.com]

Prevention

  • The negative outcome of psychological counseling raises doubts as to whether duodenal or prepyloric ulcer recurrences can be prevented by such a therapeutic approach.[ncbi.nlm.nih.gov]
  • J. and Williams, R., H 2 receptor antagonists and antacids in the prevention of acute gastrointestinal hemorrhage in fulminant hepatic failure, Lancet, i, ‎ Seite 88 - 8.[books.google.com]
  • J. and Williams, R., H 2 receptor antagonists and antacids in the prevention of acute gastrointestinal hemorrhage in fulminant hepatic failure, Lancet, i, ‎ Pagina 88 - 8.[books.google.ro]
  • These foods may prevent new ulcers from forming and decrease recovery time from current ulcers. Fruits and vegetables are rich in antioxidants, which also reduce symptoms.[livestrong.com]
  • Normally, once a paraesophageal hernia is identified, it should be treated surgically with reduction of the herniated stomach with gastropexy to prevent reherniation and herniorraphy (or prosthetic mesh) of the diaphragma [ 13 , 14 ].[wjes.biomedcentral.com]

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