Presentation
All patients presenting with active DU should therefore be investigated for evidence of previous prepyloric ulceration. [ncbi.nlm.nih.gov]
In one third of patients, the presentation is less obvious, resulting in significant delays in diagnosis of peritonitis. [aclr.com.es]
Objective To identify the incidence of carcinoma stomach in patients presenting with acid peptic ulcer disease. [ispub.com]
Treatment and prognosis Treatment depends on the clinical presentation. [radiopaedia.org]
Entire Body System
- Pain
A higher proportion of patients on omeprazole became free of pain during the first week of treatment (p less than 0.05). No major clinical or biochemical side-effects were noted. [ncbi.nlm.nih.gov]
Consult with a medical practitioner. ...Read more 7 How do you control ulcer pains? Treat the cause: Gastrointestinal ulcers will continue to cause pain until the cause is removed or treated. [healthtap.com]
pain and found to have significant tenderness on her physical examination. [surgicaloasis.com]
Case report A 19-year-old man presented to the emergency department with a history of abdominal pain, nausea and anorexia from 4- days ago. Abdominal pain was periodic during this period. [aclr.com.es]
Burning or Gnawing Stomach Pain The most common symptom of an antral ulcer is a burning or gnawing pain in the stomach. Typically, sensations of pain localize between the navel and the breastbone and may be worse when a person's stomach is empty. [livestrong.com]
- Weight Loss
Weight Loss or Fatigue A person's body may be unable to absorb necessary nutrients from ingested foods due to the presence of an antral ulcer. Consequently, people can experience symptoms of increased fatigue or weight loss, the UMMC reports. [livestrong.com]
On occasion, the dysphagia can be severe enough to cause debilitation and significant weight loss. Chronic aspiration and repetitive respiratory infection are common associated complaints. [quizlet.com]
Systemic Weight loss Anaemia if dripping Complications Bleed - malaena or haematemesis Perforation Gastric outflow obstruction - suspect if vomiting, esp if old food/ copious/ persistent. [gog.net.nz]
Other symptoms may include: Bloated feeling Burping Lack of appetite or weight loss Nausea Bloody or dark poop Vomiting Small ulcers may not cause any symptoms. But if you notice any of these signs, talk to your doctor. [webmd.com]
Symptoms of peptic ulcer Symptoms of peptic ulcer very with location of the ulcer and the patient age. • Abdominal discomfort • Pain or nausea (pain is located in the epogastrium; not radiate) Waterbrash • Waterbrash • Loss of appetite and weight loss [slideshare.net]
- Anemia
A lesion associated with large diaphragmatic hernia and chronic blood loss anemia. Gastroenterology. 1986, 91: 338-342. [wjes.biomedcentral.com]
If bleeding continues for a long time, it may lead to anemia with weakness and fatigue. If bleeding is heavy, blood may appear in vomit or bowel movements, which may appear dark red or black. [cdc.gov]
There are several different symptoms which should be monitored as there are some fatal effects of an ulcer such as stomach perforation or penetration that could cause bleeding and further complications such as anemia and even death. [naturalremedies.org]
Pernicious anemia and subsequent cancer: a population-based cohort study. Cancer 1993 ;71: 745 - 750 53. Moller H, Nissen A, Mosbech J. [nejm.org]
Signs and symptoms of PUD include dyspepsia, GI bleeding, anemia, and gastric outlet obstruction. Dyspepsia is a nonspecific term denoting upper abdominal discomfort that is thought to arise from the upper GI tract. [gastrointestinalatlas.com]
- Surgical Procedure
This volume covers surgical procedures of the stomach and includes sections on procedures for ulcer disease, procedures for neoplastic disease, operations for postgastrectomy syndromes, bariatric operations, and other gastric operations. [books.google.com]
When more information is available it may be possible to define which of the different factors are important in each instance and therefore to offer individual patients the surgical procedure appropriate to their specific needs. [ncbi.nlm.nih.gov]
[…] in early stage instead of a major surgical procedure. [ispub.com]
Because only the Inpatient Register — and not the registries used for follow-up — had data on surgical procedures in the cohort, information on operations performed after 1983 was not available to us. [nejm.org]
A more aggressive surgical procedure is then recommended, such as pyloroplasty or an antral resection. 3.2.1.6. [ptolemy.ca]
- Fatigue
Weight Loss or Fatigue A person's body may be unable to absorb necessary nutrients from ingested foods due to the presence of an antral ulcer. Consequently, people can experience symptoms of increased fatigue or weight loss, the UMMC reports. [livestrong.com]
If bleeding continues for a long time, it may lead to anemia with weakness and fatigue. If bleeding is heavy, blood may appear in vomit or bowel movements, which may appear dark red or black. [cdc.gov]
Gastrointestinal
- Vomiting
Bloody Stools or Vomit If an antral ulcer begins to bleed, people can notice blood in their stools or vomit. [livestrong.com]
56 year-old man with hematemesis (vomiting blood) and melena (black, tarry stools). Endoscopy revealed this 1 cm prepyloric ulcer, which was no longer bleeding. [endoatlas.com]
This text then discusses the general symptoms of dyspepsia, including discomfort, pain, heartburn, flatulence, acid eructation, nausea, vomiting, and visceral tenderness. [books.google.ro]
Afferent loop syndrome is associated with postprandial epigastric pain and nonbilious vomiting that is then relieved by projectile bilious vomiting. The detection of distended afferent loop on CT is diagnostic. [gastrotraining.com]
- Nausea
This text then discusses the general symptoms of dyspepsia, including discomfort, pain, heartburn, flatulence, acid eructation, nausea, vomiting, and visceral tenderness. [books.google.ro]
Nausea, Vomiting or Belching A person with an antral ulcer can develop upset stomach symptoms, including nausea, vomiting or belching, the University of Maryland Medical Center explains. [livestrong.com]
[…] upper GI bleeding Type 1 (along lesser curvature of stomach) Type 2 (two ulcers, one gastric and the other duodenal) Type 3 (pre-pyloric ulcer) Type 4 (proximal gastroesophageal ulcer) Type 5 (anywhere) History / PE : Melena Abdominal pain Hematemesis Nausea [medlibes.com]
This usually causes no symptom; however, some patients develop persistent burning epigastric pain and chronic nausea that is aggravated by meals. There is no effective treatment. [gastrotraining.com]
- Epigastric Pain
Abstract A 77 years old man had a sudden onset of an epigastric pain and melena in the course of acute respiratory failure. [jlc.jst.go.jp]
The player requires Flash Player plugin Case description This 42 year-old female, who presented severe epigastric pain. A small ulcer is observed at the anterior wall, giving the sensation that this ulcer has been divided in two Satellite ulcers. [medtube.net]
Efferent loop syndrome is associated with epigastric pain, distension, and bilious vomiting; operation is the treatment of choice. [gastrotraining.com]
On August 18,1976, he was hospitalized because of severe epigastric pain which developed abruptly. The pain was almost gone in three days. [webview.isho.jp]
Clinical Features and Natural History Top The leading symptom is epigastric pain or epigastric discomfort. [empendium.com]
- Dyspepsia
This text then discusses the general symptoms of dyspepsia, including discomfort, pain, heartburn, flatulence, acid eructation, nausea, vomiting, and visceral tenderness. [books.google.ro]
Signs and symptoms of PUD include dyspepsia, GI bleeding, anemia, and gastric outlet obstruction. Dyspepsia is a nonspecific term denoting upper abdominal discomfort that is thought to arise from the upper GI tract. [gastrointestinalatlas.com]
Dyspepsia not associated with peptic ulcer 10. Undiagnosed dyspepsia (a test-and-treat strategy) a 11. Prevention of development of ulcers and their complications before or during a long-term NSAID treatment b 12. [empendium.com]
Diagnosis It is difficult to differentiate duodenal ulcer from other causes of dyspepsia (gastric ulcer, non-ulcer dyspepsia, reflux oesophagitis, gastric cancer, gallstone) with confidence on clinical grounds alone. [surgwiki.com]
- Flatulence
This text then discusses the general symptoms of dyspepsia, including discomfort, pain, heartburn, flatulence, acid eructation, nausea, vomiting, and visceral tenderness. [books.google.ro]
2 months i am taking Carbo Veg 200 before meals..and nux vomica after meals..it relieved my symptoms by 60%..still in the evening my throat feels heavy..mild chest pain..mild shortness of breath..food comees up in throat,,and continous burps.lot of flatulance [abchomeopathy.com]
Pain was the most frequent symptom in 58 (85%) followed by vomiting in 13 (19%), heart-burn and G.I. bleeding in 7 (10%) and flatulence in 2 (3%) patients. [jpma.org.pk]
Workup
CT workup and en-bloc resection if an occult or obvious malignancy is present. Complications of Surgery Early Duodenal stump leakage, gastric retention, haemorrhage in post-operative period. [gog.net.nz]
Microbiology
- Helicobacter Pylori
Original Articles 17 Downloads 15 Citations Abstract Helicobacter pylori is associated with peptic ulcer, and a causal relationship has been postulated. We investigated the association between Helicobacter pylori and gastric acid output. [springerlink.com]
Helicobacter pylori antibody was positive. Right: Prepyloric antral ulcer in a 56 year-old man undergoing endoscopy for evaluation of abdominal pain. [endoatlas.com]
Risk factors include 2,4 : Helicobacter pylori infection NSAIDs corticosteroids severe physiological stress/illness (e.g. admission to intensive care) Zollinger-Ellison syndrome The majority of cases are due to infection with Helicobacter pylori. [radiopaedia.org]
The factors that participate frequently in occurrence of peptic perforation are helicobacter pylori infection and chronic use of NSAIDs [ 9 ]. [aclr.com.es]
Helicobacter pylori and peptic ulceration A common factor in peptic ulcer causation is the presence of the infectious agent Helicobacter pylori. [news-medical.net]
Treatment
We conclude that a daily dose of 300 mg ranitidine is superior to 200 mg ranitidine in the treatment of duodenal and prepyloric ulcer and that the short-term use of ranitidine seems to be safe for the treatment of these ulcers. [ncbi.nlm.nih.gov]
Prognosis
Treatment and prognosis Treatment depends on the clinical presentation. [radiopaedia.org]
Waquaruddin Ahmed, Huma Qureshi, Syed Ejaz Alarn, Sarwar Jehan Zuberi ( PMRC Research Centre, Jinnah Postgraduate Medical Centre, Karachi-35. ) ABSTRACT Retrospective analysis of 115 cases of perforated duodenal ulcer was done to determine the long term prognosis [jpma.org.pk]
- if hard to distinguish, better prognosis if Ca --> 50-75% cure chance. Biopsy should be taken at the same time for H pylori. - Ideally 7+ bx (10=good) and brush biopsy. - False +ve rare, false -ve in 5-10%. [gog.net.nz]
The poor prognosis of gastric cancer also makes ascertainment bias an unlikely explanation. [nejm.org]
Etiology
This is the most common etiology of type 3 ulcers, or prepyloric ulcers. Further Reading Peptic Ulcer - What are Peptic Ulcers? Peptic Ulcer Symptoms Peptic Ulcer Diagnosis Living with Peptic Ulcer Disease Peptic Ulcer Treatments [news-medical.net]
The etiological factors responsible for peptic perforation vary depending upon sociodemographic factors [ 8 - 10 ]. [aclr.com.es]
Definition, Etiology, Pathogenesis Top Peptic ulcer disease ( PUD ) is a recurring formation of gastric and/or duodenal peptic ulcers. [empendium.com]
[…] is unknown, but spirochetes, fusiform bacilli, and other bacteria are often present in the developing lesion, and protein and vitamin deficiency with lowered resistance to infection may play a role in the etiology. venereal ulcer a nonspecific term referring [medical-dictionary.thefreedictionary.com]
(Sudden large bleeding can be life threatening) • Cancer (Helicobacter pylori as the etiological factor making it 3-6 times likely to develop stomach cancer) • Perforation (hole in the wall) • Penetration. 14. Diagnosis of peptic ulcer 15. [slideshare.net]
Epidemiology
E.H.); the Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Md. (A.W.H., J.F.F.); the International Epidemiology Institute, Rockville, Md. (W. [nejm.org]
Methods Statistics Trigonometry Medical & Nursing Anatomy Anesthesiology Audiology Bacteriology Biochemistry Bioethics Biomedical Science Cardiology Cardiovascular Childbirth Chiropractic Dentistry Dermatology Diagnostic Imaging Drugs Endocrinology Epidemiology [brainscape.com]
Dig Surg 27: 161-169 Lau JY, Sung J, Hill C, Henderson C, Howden CW, et al. (2011) Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion 84: 102-113. [aclr.com.es]
Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion. 2011;84(2):102-13. doi: 10.1159/000323958. Review. PubMed PMID: 21494041. [empendium.com]
Epidemiology • Peptic ulcers are common and it has been estimated that up to 10% of the population has an ulcer and annual incidence of symptomatic peptic ulcer about 0.3%. • Duodenal ulcers are four times as common as gastric ulcers and occur mainly [slideshare.net]
Pathophysiology
A second outstanding feature of this volume is its success in balanc ing basic pathophysiology with practical considerations of clinical man agement. [books.google.ro]
Prevention
J. and Williams, R., H 2 receptor antagonists and antacids in the prevention of acute gastrointestinal hemorrhage in fulminant hepatic failure, Lancet, i, Pagina 88 - 8. [books.google.ro]
J. and Williams, R., H 2 receptor antagonists and antacids in the prevention of acute gastrointestinal hemorrhage in fulminant hepatic failure, Lancet, i, الصفحة 88 - 8. [books.google.com]
The negative outcome of psychological counseling raises doubts as to whether duodenal or prepyloric ulcer recurrences can be prevented by such a therapeutic approach. [ncbi.nlm.nih.gov]
Prevention Tips There are some great tips you should adhere to if you want to prevent peptic ulcers from developing. [naturalremedies.org]
This creates a feedback loop which keeps the acid level high while preventing inhibition of the acid-secreting cells. [news-medical.net]