Presentation
Data are presented to show a significant absorption of lidocaine through diseased skin when lidocaine cream is used as a local anesthetic. [jaad.org]
Amlodipine Besylate - 20 seconds ago Vytorin and Claustrophobia - 22 seconds ago Xeloda and Haemoglobinuria Present - 27 seconds ago Tamsulosin and Sinemet drug interaction - 31 seconds ago [ehealthme.com]
In the present study, we aimed to identify the human enzymes that are responsible for prilocaine- and lidocaine-induced methemoglobinemia. [eurekamag.com]
Entire Body System
- Pain
J Pain Res. 2017 May 10;10:1105-1109. doi: 10.2147/JPR.S131029. eCollection 2017. J Pain Res. 2017. PMID: 28546768 Free PMC article. [pubmed.ncbi.nlm.nih.gov]
as they reduce dental phobia, especially in children, by mitigating discomfort and pain. [semanticscholar.org]
Journal of Dental Anesthesia and Pain Medicine 21(4): 357-361, 2021 Methemoglobinemia in the newborn infant--caused by prilocaine?-- A case report. [eurekamag.com]
Cardiovascular
- Cyanosis
[…] of therapeutics 2017 A 47-year-old female with medical history of vulvar cancer and HIV undergoing chemoradiation sent by the oncology clinic to the emergency department for worsening dyspnea, fatigue, hypoxia to 78% on room air, and gradual onset of cyanosis [semanticscholar.org]
During surgical wound dressing the boy showed cyanosis, decreased peripheral oxygen saturation and potentially suffered a general seizure. [pubmed.ncbi.nlm.nih.gov]
- Hypotension
[…] ventricular dysrhythmias with sodium bicarbonate (1–2 mmol/kg up to 100 mmol) IV every 1-2 minutes until perfusing rhythm; can use amiodarone; AVOID calcium channel blockers, beta blockers, local anaesthetics Treat seizures with benzodiazepines Treat hypotension [rch.org.au]
- Hypertension
Precautions - hypersensitivity to egg yolk, soya or peanut protein Adverse events reported after lipid emulsion infusion: Allergy and anaphylaxis Interference with laboratory testing Pancreatitis (rare) Venous thromboembolism (rare) Pulmonary hypertension [rch.org.au]
Skin
- Dermatitis
British Journal of Dermatology 173(1): 259-261, 2015 Seizures and Methemoglobinemia After Topical Application of Eutectic Mixture of Lidocaine and Prilocaine on a 3.5-Year-Old Child with Molluscum Contagiosum and Atopic Dermatitis. [eurekamag.com]
Neurologic
- Paresthesia
[…] circulatoire pathologie Cardiopathie Système nerveux pathologie Trouble excitabilité Trouble neurologique Trouble rythme cardiaque Trouble sensibilité Keyword (en) Regional anesthesia Local anesthetic Apparatus failure Case study Face Tourniquet Human Paresthesia [pascal-francis.inist.fr]
- Agitation
Examination Early clinical features include: Tinnitus Difficulty with visual focus Dizziness or lightheadedness Anxiety, agitation, confusion, disorientation, drowsiness Perioral and/or tongue numbness Metallic taste More severe toxicity manifests by: [rch.org.au]
Treatment
Drug treatments / 002B02U Drug toxicity and drugs side effects treatment / 002B02U01 Toxicity: nervous system and muscle Discipline Drugs toxicity and drug intoxications Toxicology Origin Inist-CNRS Database PASCAL INIST identifier 2201172 Sauf mention [pascal-francis.inist.fr]
In severe cases intensive care and antidote treatment with Methylene blue may be required. [unboundmedicine.com]
In severe cases intensive care and antidote treatment with Methylene blue may be… One Citation [semanticscholar.org]
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. [ehealthme.com]
Prevention
[…] terminal R wave in aVR) Management Immediately cease administration of the local anaesthetic Call for help Resuscitation Standard procedures and supportive care If there is evidence of cardiotoxicity, immediate intubation and ventilation is necessary to prevent [rch.org.au]