Presentation
Malignant primary cardiac tumors are very rare.Desmoplastic small round cell tumors are also rare tumors and,when present, are generally found in the abdomen. [ncbi.nlm.nih.gov]
Entire Body System
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Congestive Heart Failure
Clinical features The most common presentation of cardiac tumors is evidence of congestive heart failure due to obstruction and/or valvular insufficiency. [accesssurgery.mhmedical.com]
Dyspnea is the commonest symptom in 60%, followed by chest pain in 28%, congestive heart failure in 28%, palpitations in 24%, fever in 14%, myalgia in 10% and embolism in 5%. [1] Although in adults cardiac tumors are mostly benign, 25% can be malignant [heartviews.org]
Coronary artery diseases, congestive heart failure, valvular diseases, and arrhythmias are the primary etiologic causes. Cardiac neoplasms may have similar presentations but have been often overlooked because of rare occurrence. [indianjcancer.com]
Complications due to Cardiac Myxosarcoma could include: Congestive heart failure, depending on the location of the tumor in the heart Increased risk for thromboembolism (blood clot obstructing a blood vessel) Metastasis of the tumor to other sites in [dovemed.com]
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Large Pericardial Effusion
A CT of the chest did not reveal embolism but did show a large pericardial effusion and noted for abnormal configuration of the left ventricular wall concerning for a mass. [symbiosisonlinepublishing.com]
Transthoracic echocardiography demonstrated large pericardial effusion with cardiac tamponade. He underwent emergency pericardiocentesis and 1060 ml of hemorrhagic fluid was aspirated. [heartviews.org]
Chest X-ray demonstrated cardiomegaly and echocardiogram demonstrated a large pericardial effusion. The patient underwent pericardiocentesis, draining 1.2 litres of haemorrhagic pericardial fluid. [ommegaonline.org]
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High Fever
Case 2 A 37-year-old lady presented with 3 months history of right-sided pleuritic chest pain, high fever, night sweats and dry cough. She was extremely breathless with poor oxygenation and her blood tests showed presence of anaemia. [cardiothoracicsurgery.biomedcentral.com]
fever *hyperthermia [高体温症、過温症] 【高安動脈炎】*Takayasu arteritis 【高安病】*Takayasu's disease ( 高安幹動脈炎) (甲) 【甲介炎】*conchitis (硬) 【硬化腫】*scleroma 【硬化症】*sclerosis *[ 硬結] induration 【硬化性胃炎】*sclerotic gastritis 【硬化性骨炎】*sclerotic osteitis 【硬化性苔癬】*lichen sclerosus[L] 【 [medo.jp]
Cardiovascular
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Cardiomegaly
Chest x ray may show cardiomegaly, infiltrates suggestive of congestive cardiac failure, pleural effusion, lung nodules, cardiac mass or left hemidiaphragm paralysis. [cardiothoracicsurgery.biomedcentral.com]
Chest radiograph demonstrated cardiomegaly and small bilateral pleural effusions. Transthoracic echocardiography demonstrated large pericardial effusion with cardiac tamponade. [heartviews.org]
Chest X-ray showed cardiomegali and ECG was consisted with atrial fibrillation. [ascopubs.org]
Chest X-ray demonstrated cardiomegaly and echocardiogram demonstrated a large pericardial effusion. The patient underwent pericardiocentesis, draining 1.2 litres of haemorrhagic pericardial fluid. [ommegaonline.org]
[…] endocardial fibroelastosis (略 EFE/略 ECFE/略 EF) 【心嚢炎】*pericarditis 心膜炎 【心嚢気腫】*pneumopericardium 【心嚢血腫】【心嚢出血】*hemopericardium 【心嚢水腫】*hydropericardium 【心嚢蓄膿】*pyopericardium 【心破裂】*rupture of heart *cardiac rupture *cardiorrhexis 【心肥大】*cardiac hypertrophy *cardiomegaly [medo.jp]
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Heart Disease
She had a previous history of chronic atrial fibrillation, ischemic heart disease, osteoarthritis and deep vein thrombosis. Clinical examination, blood tests and chest x ray were unremarkable. [cardiothoracicsurgery.biomedcentral.com]
Braunwald’s heart disease 7a ed. Filadelfia, EE.UU.: Elsevier Saunders; 2005. Pp. 1741-1755. 2. Silverman NA. Primary cardiac tumors. Ann Surg 191:127-138, 1980. 3. Rettmarr K, Stierle U, Sheikhzadeh A y col. Primary angiosarcoma of the heart. [siicsalud.com]
Heart disease: a textbook of cardiovascular medicine. 5th ed. Philadelphia, Pa: Saunders, 1997 ; 1464-1477. Google Scholar 2 Fraser RS, Muller NL, Colman N, Pare PD. Anterior mediastinal masses. [pubs.rsna.org]
disease 【冠動脈塞栓症】*coronary embolism 【陥没乳頭】*inverted nipple 【Q熱】*Q fever (キ) 【キノコ状真菌症】*mycosis fungoides (略 MF) ( 菌状息肉症) (気) 【気圧歯痛】*aerodontalgia 【気管異物】*tracheal foreign body 【気管炎】*tracheitis 【気管気管支リンパ節疾患】*tracheobronchial adenopathy 【気管支アレルギー】*bronchial [medo.jp]
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Diminished Heart Sounds
Signs including hypotension, malaise, tachycardia, diminished heart sounds and a friction rub may be present. Intractable cardiac failure can result from cardiac tamponade. [symbiosisonlinepublishing.com]
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Exertional Chest Pain
We present a case of a 35 year old man with recurrent episodes of exertional chest pain and who was diagnosed with primary cardiac osteosarcoma. Cardiac osteosarcomas are rare but must be suspected. [indianjcancer.com]
Musculoskeletal
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Left Shoulder Pain
Further history revealed left shoulder pain. He asked to be treated for his ongoing “Flu”. He had undergone numerous treatments under his primary care’s guidance including antibiotics. [symbiosisonlinepublishing.com]
Workup
The mass reduced its size ( Figure 3 ), an angioresonance ruled out major vessel invasion, and a staging workup showed no distant metastasis. [jtd.amegroups.com]
During the initial workup for the left wrist lesion, a frontal chest radiograph showed no significant abnormality (Figure 4A); the patient subsequently underwent below-the-elbow amputation. [appliedradiology.com]
Patient was referred to the cancer center and a 6-month postoperative workup with CT scan and PET scan reported liver metastasis only. Patient underwent successful chemotherapy and was tumor free during his one-year follow up. [omicsonline.org]
Angiography
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Mural Thrombus
Lee EY, Jeon ES, Choi JO, Lee SC, Park SW et al. (2011) Primary cardiac sarcoma mimicking mural thrombus. Eur J Echocardiogr 12(9):713. Dawson WB, Mayo JR, Müller NL (1900) Computed tomography of cardiac and pericardial tumors. [symbiosisonlinepublishing.com]
X-Ray
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Left Pleural Effusion
Chest roentgenograms showed enlargement of the cardiac shadow and left pleural effusion. Transthoracic echocardiography and chest magnetic resonance imaging showed a tumor in the right atrium, and pericardial effusion. [ncbi.nlm.nih.gov]
(a) Posteroanterior chest radiograph shows a left pleural effusion. Note the metastatic pulmonary nodule (short arrow) and the adenopathy in the aortopulmonary window (long arrow). [pubs.rsna.org]
Treatment
Although resection is not curative in most cases, surgery remains the treatment of choice for PCS and has a definite palliative significance. [ncbi.nlm.nih.gov]
Prognosis
Tumor spread from primary cardiac sarcoma to the bone is very rare and has a poor prognosis. Only six cases have been reported in the literature. We present a 32-year-old female patient with bone metastases from primary cardiac sarcoma. [ncbi.nlm.nih.gov]
Etiology
Percutaneous pericardial biopsy was done to look for specific etiology. After pericardial biopsy, a 4-F pigtail catheter was left in the pericardial cavity for further aspiration. [heartviews.org]
Coronary artery diseases, congestive heart failure, valvular diseases, and arrhythmias are the primary etiologic causes. Cardiac neoplasms may have similar presentations but have been often overlooked because of rare occurrence. [indianjcancer.com]
Etiology of these tumors is unknown, though some can present as second malignancies in patients treated with radiotherapy for previous cancers. [oncolink.org]
Each one of the cases presented totally different symptoms, but a similar etiological substrate. [revespcardiol.org]
(Etiology) The exact cause and mechanism of formation of Cardiac Myxosarcoma is unknown. [dovemed.com]
Epidemiology
METHODS: Patients with primary cardiac sarcoma and noncardiac sarcoma, diagnosed between 1988 and 2005, were identified in the Surveillance, Epidemiology, and End Results (SEER) database. [ncbi.nlm.nih.gov]
Medicine, University of Toronto, Toronto/CA 5 Division Of Pathology, University Health Network, Toronto/CA 6 Division Of Cardiovascular Surgery, University Health Network, Toronto/CA 7 National Taiwan University College Of Public Health, Institute of Epidemiology [oncologypro.esmo.org]
Epidemiology Primary cardiac tumors have an estimated autopsy prevalence of 0.001-0.03% 2. [radiopaedia.org]
Epidemiology Primary cardiac tumors are rare with an overall incidence of 0.02 percent. Malignant tumors metastatic to the heart are much more common with an incidence of 1.23 percent. [accesssurgery.mhmedical.com]
Pathophysiology
Pathophysiology Cardiac tumors arise from various cells in the heart. Clinical effects of these tumors are based chiefly on the size and location of the mass. [accesssurgery.mhmedical.com]
Prevention
University of Toronto, Toronto/CA 5 Division Of Pathology, University Health Network, Toronto/CA 6 Division Of Cardiovascular Surgery, University Health Network, Toronto/CA 7 National Taiwan University College Of Public Health, Institute of Epidemiology and Preventive [oncologypro.esmo.org]
The treatment usually begins with chemotherapy to prevent spread and shrink the tumor and thereafter surgery may be carried out to remove the section of cancerous bone. [news-medical.net]
Preventive Cardiovascular Research Centre Kermanshah, Kermanshah University of Medical Sciences, Iran *Corresponding author: Feridoun Sabzi, Preventive Cardiovascular Research Centre Kermanshah, Kermanshah University of Medical Sciences, Kermanshah, Iran [austinpublishinggroup.com]
Learn about sarcoma treatment options and prevention of sarcoma recurrence from an expert at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center. [hopkinsmedicine.org]