We present a patient with long-term remission after primary cardiac sarcoma resection. [ncbi.nlm.nih.gov]

In one of the published series, 29% of patients had pericardial effusion at presentation. [3] Our patient had massive pericardial effusion with tamponade at the initial presentation. [heartviews.org]

Case presentations Case 1 An 84-year-old lady presented with 6 weeks history of acute onset dyspnoea, lethargy and repeated haemoptysis. [cardiothoracicsurgery.biomedcentral.com]

• Congestive Heart Failure

  Clinical features The most common presentation of cardiac tumors is evidence of congestive heart failure due to obstruction and/or valvular insufficiency. [accesssurgery.mhmedical.com]

  Dyspnea is the commonest symptom in 60%, followed by chest pain in 28%, congestive heart failure in 28%, palpitations in 24%, fever in 14%, myalgia in 10% and embolism in 5%. [1] Although in adults cardiac tumors are mostly benign, 25% can be malignant [heartviews.org]

  Coronary artery diseases, congestive heart failure, valvular diseases, and arrhythmias are the primary etiologic causes. Cardiac neoplasms may have similar presentations but have been often overlooked because of rare occurrence. [indianjcancer.com]

  Complications due to Cardiac Myxosarcoma could include: Congestive heart failure, depending on the location of the tumor in the heart Increased risk for thromboembolism (blood clot obstructing a blood vessel) Metastasis of the tumor to other sites in [dovemed.com]

• Chest Discomfort

  Case Presentation A 58-year-old woman was admitted to our hospital complaining of chest discomfort, dyspnea, hoarseness, and a mild headache. Her symptoms had begun one month earlier. [iranjradiol.com]

  Case report A sixty-year-old man presented to an emergency room with rapidly progressing shortness of breath and chest discomfort in April 2013. [springerplus.springeropen.com]

  Mechanical symptoms (eg, dyspnea, chest discomfort) result from compression of cardiac chambers or coronary arteries or from pericardial irritation or tamponade caused by growth or hemorrhage within the pericardium. [merckmanuals.com]

• Large Pericardial Effusion

  A CT of the chest did not reveal embolism but did show a large pericardial effusion and noted for abnormal configuration of the left ventricular wall concerning for a mass. [symbiosisonlinepublishing.com]

  Chest radiograph demonstrated cardiomegaly and small bilateral pleural effusions. Transthoracic echocardiography demonstrated large pericardial effusion with cardiac tamponade. [heartviews.org]

  Chest X-ray demonstrated cardiomegaly and echocardiogram demonstrated a large pericardial effusion. The patient underwent pericardiocentesis, draining 1.2 litres of haemorrhagic pericardial fluid. [ommegaonline.org]

• High Fever

  Case 2 A 37-year-old lady presented with 3 months history of right-sided pleuritic chest pain, high fever, night sweats and dry cough. She was extremely breathless with poor oxygenation and her blood tests showed presence of anaemia. [cardiothoracicsurgery.biomedcentral.com]

  […] hypercapnia 【高タンパク血症】【高蛋白血症】*hyperproteinemia 【高張膀胱】*hypertonic bladder 【高頭蓋症】*hypsicephaly *hypsicrany (＝塔状頭蓋症) 【高トリグリセリド血[症]】*hypertriglyceridemia 【高ナトリウム血症】*hypernatremia (＝ナトリウム過剰血症) 【高尿酸血症】*hyperuricemia 【高尿酸尿症】*hyperuricuria *hyperlithuria 【高熱】*high [medo.jp]

• Epigastric Pain

  pain and weight loss for 3 months. [heartviews.org]

• Cardiomegaly

  Chest X-ray showed cardiomegali and ECG was consisted with atrial fibrillation. [ascopubs.org]

  Chest x ray may show cardiomegaly, infiltrates suggestive of congestive cardiac failure, pleural effusion, lung nodules, cardiac mass or left hemidiaphragm paralysis. [cardiothoracicsurgery.biomedcentral.com]

  Chest radiograph demonstrated cardiomegaly and small bilateral pleural effusions. Transthoracic echocardiography demonstrated large pericardial effusion with cardiac tamponade. [heartviews.org]

  Chest X-ray demonstrated cardiomegaly and echocardiogram demonstrated a large pericardial effusion. The patient underwent pericardiocentesis, draining 1.2 litres of haemorrhagic pericardial fluid. [ommegaonline.org]

  […] endocardial fibroelastosis (略 EFE/略 ECFE/略 EF) 【心嚢炎】*pericarditis ^＝心膜炎 【心嚢気腫】*pneumopericardium 【心嚢血腫】【心嚢出血】*hemopericardium 【心嚢水腫】*hydropericardium 【心嚢蓄膿】*pyopericardium 【心破裂】*rupture of heart *cardiac rupture *cardiorrhexis 【心肥大】*cardiac hypertrophy *cardiomegaly [medo.jp]

• Heart Disease

  She had a previous history of chronic atrial fibrillation, ischemic heart disease, osteoarthritis and deep vein thrombosis. Clinical examination, blood tests and chest x ray were unremarkable. [cardiothoracicsurgery.biomedcentral.com]

  Heart transplantation in patients with malignant disease. J Heart Transplant 9:627-629, 1990. 41. Frota-Filho JD, Lucchese FA, Leães P, Valente LA, Vieira MS, Blacher C. Primary cardiac angiosarcoma. A therapeutical dilemma. [siicsalud.com]

  Primary tumors of the heart. In: Braunwald E, eds. Heart disease: a textbook of cardiovascular medicine. 5th ed. Philadelphia, Pa: Saunders, 1997 ; 1464-1477. Google Scholar 2 Fraser RS, Muller NL, Colman N, Pare PD. Anterior mediastinal masses. [pubs.rsna.org]

  *fatty infiltration of heart *steatosis cordis[L] 【心身障害】*psychosomatic disorder 【心臓炎】*carditis ^＝心筋炎 【心臓下垂症】*cardioptosis 【心臓恐怖症】*cardiophobia 【心臓疾患】【心臓病】【心疾患】*heart disease *cardiac disease *cardiopathy 【心臓心膜炎】*cardiopericarditis 【心臓性肝硬変】【心性肝硬変】*cardiac [medo.jp]

• Diminished Heart Sounds

  Signs including hypotension, malaise, tachycardia, diminished heart sounds and a friction rub may be present. Intractable cardiac failure can result from cardiac tamponade. [symbiosisonlinepublishing.com]

• Exertional Chest Pain

  We present a case of a 35 year old man with recurrent episodes of exertional chest pain and who was diagnosed with primary cardiac osteosarcoma. Cardiac osteosarcomas are rare but must be suspected. [indianjcancer.com]

The mass reduced its size ( Figure 3 ), an angioresonance ruled out major vessel invasion, and a staging workup showed no distant metastasis. [jtd.amegroups.com]

During the initial workup for the left wrist lesion, a frontal chest radiograph showed no significant abnormality (Figure 4A); the patient subsequently underwent below-the-elbow amputation. [appliedradiology.com]

Patient was referred to the cancer center and a 6-month postoperative workup with CT scan and PET scan reported liver metastasis only. Patient underwent successful chemotherapy and was tumor free during his one-year follow up. [omicsonline.org]

• Left Pleural Effusion

  Chest roentgenograms showed enlargement of the cardiac shadow and left pleural effusion. Transthoracic echocardiography and chest magnetic resonance imaging showed a tumor in the right atrium, and pericardial effusion. [ncbi.nlm.nih.gov]

  (a) Posteroanterior chest radiograph shows a left pleural effusion. Note the metastatic pulmonary nodule (short arrow) and the adenopathy in the aortopulmonary window (long arrow). [pubs.rsna.org]

• Mural Thrombus

  Lee EY, Jeon ES, Choi JO, Lee SC, Park SW et al. (2011) Primary cardiac sarcoma mimicking mural thrombus. Eur J Echocardiogr 12(9):713. Dawson WB, Mayo JR, Müller NL (1900) Computed tomography of cardiac and pericardial tumors. [symbiosisonlinepublishing.com]

Discussion and conclusion Optimal treatment strategy for primary cardiac sarcomas is not established. [springerplus.springeropen.com]

Although resection is not curative in most cases, surgery remains the treatment of choice for PCS and has a definite palliative significance. [ncbi.nlm.nih.gov]

Cardiac transplant has also been used as part of treatment strategies [16]. The role of radiation therapy, either as adjuvant or primary treatment, is limited due to its cardiotoxicity [17,18]. [ommegaonline.org]

Tumor spread from primary cardiac sarcoma to the bone is very rare and has a poor prognosis. Only six cases have been reported in the literature. We present a 32-year-old female patient with bone metastases from primary cardiac sarcoma. [ncbi.nlm.nih.gov]

Outcomes and prognosis The prognosis of resectable benign tumors is usually very good with low recurrence rates depending on the type of tumor. [accesssurgery.mhmedical.com]

Cytology did not reveal any malignant etiology. [heartviews.org]

Etiology of these tumors is unknown, though some can present as second malignancies in patients treated with radiotherapy for previous cancers. [oncolink.org]

Each one of the cases presented totally different symptoms, but a similar etiological substrate. [revespcardiol.org]

Coronary artery diseases, congestive heart failure, valvular diseases, and arrhythmias are the primary etiologic causes. Cardiac neoplasms may have similar presentations but have been often overlooked because of rare occurrence. [indianjcancer.com]

(Etiology) The exact cause and mechanism of formation of Cardiac Myxosarcoma is unknown. [dovemed.com]

METHODS: Patients with primary cardiac sarcoma and noncardiac sarcoma, diagnosed between 1988 and 2005, were identified in the Surveillance, Epidemiology, and End Results (SEER) database. [ncbi.nlm.nih.gov]

This timely volume covers history, epidemiology, demographics, clinical diagnosis, pathology, imaging by echo, CT and MRI of both benign and malignant cardiac tumors, either primary or secondary. [books.google.com]

Epidemiology Primary cardiac tumors have an estimated autopsy prevalence of 0.001-0.03% 2. [radiopaedia.org]

Medicine, University of Toronto, Toronto/CA 5 Division Of Pathology, University Health Network, Toronto/CA 6 Division Of Cardiovascular Surgery, University Health Network, Toronto/CA 7 National Taiwan University College Of Public Health, Institute of Epidemiology [oncologypro.esmo.org]

Epidemiology Primary cardiac tumors are rare with an overall incidence of 0.02 percent. Malignant tumors metastatic to the heart are much more common with an incidence of 1.23 percent. [accesssurgery.mhmedical.com]

Pathophysiology Cardiac tumors arise from various cells in the heart. Clinical effects of these tumors are based chiefly on the size and location of the mass. [accesssurgery.mhmedical.com]

The treatment usually begins with chemotherapy to prevent spread and shrink the tumor and thereafter surgery may be carried out to remove the section of cancerous bone. [news-medical.net]

Preventive Cardiovascular Research Centre Kermanshah, Kermanshah University of Medical Sciences, Iran *Corresponding author: Feridoun Sabzi, Preventive Cardiovascular Research Centre Kermanshah, Kermanshah University of Medical Sciences, Kermanshah, Iran [austinpublishinggroup.com]

University of Toronto, Toronto/CA 5 Division Of Pathology, University Health Network, Toronto/CA 6 Division Of Cardiovascular Surgery, University Health Network, Toronto/CA 7 National Taiwan University College Of Public Health, Institute of Epidemiology and Preventive [oncologypro.esmo.org]

Learn about sarcoma treatment options and prevention of sarcoma recurrence from an expert at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center. [hopkinsmedicine.org]