He returned to and completed school, attended summer camp, and enjoys an active happy life. He walks without precipitating pain in his feet and sleeps 9 to 10 hours every night. [ncbi.nlm.nih.gov]

Lidocaine toxicity can result in neurotoxicity, with central nervous system depression or seizures, and cardiovascular toxicity, with hypotension, arrhythmias, and cardiovascular collapse. [pediatrics.aappublications.org]

Unfortunately, neurogenic shock with collapse took place due to severe pain after debridement surgery of her feet. Genetic Analysis DNA was extracted from patients’ blood using Genomic DNA Extraction Kit (Geneaid, Taipei, Taiwan). [journals.plos.org]

Because of the lack of obvious neurological signs, patients may have seen multiple health professionals and been given a number diagnoses, including ‘plantar fasciitis’ or ‘collapsed arches’, in some cases leading to unnecessary surgery (which exacerbates [pn.bmj.com]

The implants were removed twice because of recurrent infection. Finally, the patient was treated with bilateral electrical stimulation of the ventral posterolateral thalamic nucleus, which resulted in important pain control until 3 years later. [ncbi.nlm.nih.gov]

When comparing the individual results, there is a tendency to clustering of patients in two separate groups; reduced small fiber input/no hyperalgesia and normal thermal thresholds/hyperalgesia. [ncbi.nlm.nih.gov]

When comparing the individual results, there is a tendency to clustering of patients in two separate groups; reduced small fiber input/no hyperalgesia and normal thermal thresholds/ hyperalgesia. [journals.lww.com]

This resulted in complete resolution of both allodynia and hyperalgesia. Dosage was increased to 1.8 mcg/die. [painmatters.wordpress.com]

Furthermore, the hyperalgesia and allodynia had nearly disappeared, allowing the patient to walk unassisted while wearing socks and shoes. [spandidos-publications.com]

Double and triple spikes may contribute to hyperalgesia in patients with neuropathic pain. [pn.bmj.com]

In addition to PE, mutations in SCN9A gene can also result in paroxysmal extreme pain disorder (PEPD; OMIM 167400) [12] and congenital insensitivity (or indifference) to pain (CIP; OMIM 243000) [13]. [journals.plos.org]