Symptoma

Primary Insomnia

These results are difficult to reconcile with the literature presented earlier and with other results. [ncbi.nlm.nih.gov]

Abstract Summary: The present study explores the relationship between childhood maltreatment experiences and spectral power in high-frequency EEG activity during sleep in a sample of adults experiencing primary insomnia. [insights.ovid.com]

In the present study, we found an abnormal interhemispheric homotopic resting-state FC in the ACC. [frontiersin.org]

Activities not related to the present article: disclosed no relevant relationships. Other relationships: disclosed no relevant relationships. [pubs.rsna.org]

It may be secondary either to trouble falling asleep and/or to night‐time waking, which must be persistently present (i.e. three to four times a week for several weeks) [ 2 ]. [academic.oup.com]

  • Fatigue

    As for GS, prolonged cognitive testing most likely did not contribute to cognitive arousal but more to mental fatigue, as they slept relatively well during naps. [ncbi.nlm.nih.gov]

    Daytime fatigue, mood disruption, and cognitive impairments that affect primary insomnia patients reduce social productivity and quality of life and increase risk of accidents and health care utilization ( 4 – 6 ). [pubs.rsna.org]

  • Rhinitis

    Visual acuity reduced LLT 9.1 10013036 Diplopia LLT 9.1 10000173 Abnormal sensation in eye LLT 9.1 10047340 Vertigo LLT 9.1 10065027 Sudden deafness LLT 9.1 10016825 Flushing LLT 9.1 10006461 Bronchitis NOS LLT 9.1 10015090 Epistaxis LLT 9.1 10039092 Rhinitis [clinicaltrialsregister.eu]

  • Abdominal Distension

    distension LLT 9.1 10013781 Dry mouth LLT 9.1 10001760 Alopecia LLT 9.1 10015150 Erythema LLT 9.1 10029410 Night sweats LLT 9.1 10040913 Skin rash LLT 9.1 10028411 Myalgia LLT 9.1 10003988 Back pain LLT 9.1 10018800 Gynaecomastia LLT 9.1 10036661 Priapism [clinicaltrialsregister.eu]

  • Sudden Hearing Loss

    hearing loss, unspecified LLT 9.1 10033425 Pain in extremity LLT Population Age: Adults, Elderly Gender: Male, Female Trial protocol: GB (Prematurely Ended) Trial results: View results EudraCT Number: 2011-000986-10 Sponsor Protocol Number: D1050296 [clinicaltrialsregister.eu]

  • Flushing

    […] blood shot LLT 9.1 10015946 Eye irritation LLT 9.1 10038189 Red eye LLT 9.1 10047531 Visual acuity reduced LLT 9.1 10013036 Diplopia LLT 9.1 10000173 Abnormal sensation in eye LLT 9.1 10047340 Vertigo LLT 9.1 10065027 Sudden deafness LLT 9.1 10016825 Flushing [clinicaltrialsregister.eu]

  • Night Sweats

    sweats LLT 9.1 10040913 Skin rash LLT 9.1 10028411 Myalgia LLT 9.1 10003988 Back pain LLT 9.1 10018800 Gynaecomastia LLT 9.1 10036661 Priapism LLT 9.1 10052791 Erection increased (excl priapism) LLT 9.1 10037660 Pyrexia LLT 9.1 10042438 Sudden hearing [clinicaltrialsregister.eu]

  • Retinal Hemorrhage

    hemorrhage LLT 9.1 10047544 Visual disturbance NOS LLT 9.1 10047513 Vision blurred LLT 9.1 10034960 Photophobia LLT 9.1 10008795 Chromatopsia LLT 9.1 10051819 Cyanopsia LLT 9.1 10015910 Eye blood shot LLT 9.1 10015946 Eye irritation LLT 9.1 10038189 [clinicaltrialsregister.eu]

  • Red Eye

    […] hemorrhage LLT 9.1 10047544 Visual disturbance NOS LLT 9.1 10047513 Vision blurred LLT 9.1 10034960 Photophobia LLT 9.1 10008795 Chromatopsia LLT 9.1 10051819 Cyanopsia LLT 9.1 10015910 Eye blood shot LLT 9.1 10015946 Eye irritation LLT 9.1 10038189 Red [clinicaltrialsregister.eu]

  • Photophobia

    LLT 9.1 10006790 Burning sensation NOS LLT 9.1 10020937 Hypoaesthesia LLT 9.1 10007882 Cellulitis LLT 9.1 10022000 Influenza LLT 9.1 10038870 Retinal hemorrhage LLT 9.1 10047544 Visual disturbance NOS LLT 9.1 10047513 Vision blurred LLT 9.1 10034960 Photophobia [clinicaltrialsregister.eu]

  • Diplopia

    10047513 Vision blurred LLT 9.1 10034960 Photophobia LLT 9.1 10008795 Chromatopsia LLT 9.1 10051819 Cyanopsia LLT 9.1 10015910 Eye blood shot LLT 9.1 10015946 Eye irritation LLT 9.1 10038189 Red eye LLT 9.1 10047531 Visual acuity reduced LLT 9.1 10013036 Diplopia [clinicaltrialsregister.eu]

  • Eye Irritation

    Influenza LLT 9.1 10038870 Retinal hemorrhage LLT 9.1 10047544 Visual disturbance NOS LLT 9.1 10047513 Vision blurred LLT 9.1 10034960 Photophobia LLT 9.1 10008795 Chromatopsia LLT 9.1 10051819 Cyanopsia LLT 9.1 10015910 Eye blood shot LLT 9.1 10015946 Eye [clinicaltrialsregister.eu]

  • Myalgia

    Gastrooesophageal reflux disease LLT 9.1 10019022 Haemorrhoids LLT 9.1 10000060 Abdominal distension LLT 9.1 10013781 Dry mouth LLT 9.1 10001760 Alopecia LLT 9.1 10015150 Erythema LLT 9.1 10029410 Night sweats LLT 9.1 10040913 Skin rash LLT 9.1 10028411 Myalgia [clinicaltrialsregister.eu]

  • Paresthesia

    Level 9.1 10002034 Anaemia LLT 9.1 10040756 Sinusitis NOS LLT 9.1 10016807 Fluid retention LLT 9.1 10022437 Insomnia LLT 9.1 10016998 Forehead headache LLT 9.1 10010108 Common migraine LLT 9.1 10002855 Anxiety LLT 9.1 10044565 Tremor LLT 9.1 10033987 Paresthesia [clinicaltrialsregister.eu]

  • Burning Sensation

    sensation NOS LLT 9.1 10020937 Hypoaesthesia LLT 9.1 10007882 Cellulitis LLT 9.1 10022000 Influenza LLT 9.1 10038870 Retinal hemorrhage LLT 9.1 10047544 Visual disturbance NOS LLT 9.1 10047513 Vision blurred LLT 9.1 10034960 Photophobia LLT 9.1 10008795 [clinicaltrialsregister.eu]

There is little evidence to suggest that melatonin is an effective treatment for PI. [eurekaselect.com]

EudraCT Number: 2005-002711-25 Sponsor Protocol Number: 039SC04253 Start Date * : 2005-08-01 Sponsor Name: ANGELINI Full Title: DOSE-FINDING STUDY OF TRAZODONE IN THE TREATMENT OF PATIENTS WITH PRIMARY INSOMNIA Medical condition: TREATMENT OF THE INSOMNIA [clinicaltrialsregister.eu]

SETTING Outpatient with sleep laboratory assessments in months 1 and 8 of treatment. PARTICIPANTS Ninety-five primary insomniacs, 32-64 years old and 55 age- and sex-matched general population-based, representative controls. [semanticscholar.org]

Although the absolute benefit of melatonin compared to placebo is smaller than other pharmacological treatments for insomnia, melatonin may have a role in the treatment of insomnia given its relatively benign side-effect profile compared to these agents [ncbi.nlm.nih.gov]

Further studies that collect fMRI dynamics of wakefulness and deep sleep will contribute to our better understanding the etiology and pathogenesis underlying this disorder. [frontiersin.org]

According to an epidemiologic study, insomnia is a remarkably prevalent disorder, and primary insomnia disorder affects 3%–5% of the general adult population ( 3 ). [pubs.rsna.org]

The epidemiology of insomnia: associations with physical and mental health. the HUNT-2 study. J. Psychosom. [frontiersin.org]

Epidemiology of insomnia: What we know and what we still need to learn. Sleep Med Rev. 2002; 6 :97–111. [ PubMed ] [ Google Scholar ] 3. Morin CM, LeBlanc M, Bélanger L, Ivers H, Mérette C, Savard J. [ncbi.nlm.nih.gov]

Although the significance of these findings for pathophysiologic models of primary insomnia remains unclear, our study suggests that primary insomnia is characterized by altered structural connectivity related to regulation of sleep and wakefulness, particularly [pubs.rsna.org]

Prior studies have reported that the imbalance between left and right hemispheric activity and poor coordination may contribute to the pathophysiology of insomnia. [frontiersin.org]

Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBOCONTROLLED, FLEXIBLE-DOSE, PARALLEL-GROUP STUDY OF LURASIDONE ADJUNCTIVE TO LITHIUM OR DIVALPROEX FOR THE PREVENTION OF RECURRENCE IN SUBJECTS WITH BIPOLAR I DISO... [clinicaltrialsregister.eu]

One explanation might be that completing the battery of cognitive tests increased the cognitive load, which in turn contributed to hyperactivation of cognitive functions in INS, and prevented them from falling asleep. [ncbi.nlm.nih.gov]