Presentation
She also presents a sever failure to thrive, despite adequate nutritional support by gastric tube at home. [latunisiemedicale.com]
Immune System
- Splenomegaly
She had no splenomegaly. Stool was normally colored and the urine was dark. Laboratory investigations are reported in table I. [latunisiemedicale.com]
Gastrointestinal
- Abdominal Distension
There was gradual abdominal distension due to enlargement of liver size; the left liver was palpable six cm below mid-clavicular line. She had no splenomegaly. Stool was normally colored and the urine was dark. [latunisiemedicale.com]
Urogenital
- Dark Urine
He was icteric, eutrophic, had pale stools and dark urine and hepatomegaly. His biological assessment (Table I) was in favor of PFIC 1 or 2 diagnosis. He was discharged under ursodeoxycholicacid and fat-soluble vitamins (A, D, E, K). [latunisiemedicale.com]
Treatment
The prognosis of this pathology is poor, despite adequate medical treatment and nutritional care. Liver transplantation is considered as the only curative treatment. [latunisiemedicale.com]
Prognosis
The prognosis of this pathology is poor, despite adequate medical treatment and nutritional care. Liver transplantation is considered as the only curative treatment. [latunisiemedicale.com]
Prevention
Unfortunately, this genetic counseling was not performed in the first family in our study, which could have prevented the recurrence of this serious pathology in their second child. [latunisiemedicale.com]