He developed soft tissue masses in the right heel and right elbow that were calcified or ossified on plain radiographs. MR imaging raised a suspicion of heterotopic ossification; thus, GNAS1 was analyzed. [ncbi.nlm.nih.gov]

Soft tissue masses. [online publication]. Reston (VA): American College of Radiology (ACR);. 2005. 6 p: Kitterman JA, Kantanie S, Rocke DM, Kaplan FS. Iatrogenic harm caused by diagnostic errors in fibrodysplasia ossificans progressiva. [emedicine.medscape.com]

Hornicek and Mark Gebhardt, Non-neoplastic Soft Tissue Masses That Mimic Sarcoma, Orthopedic Clinics of North America, 45, 2, (245), (2014). Dirk E. Schrander, Tim J. Welting, Marjolein M.J. Caron, Jaap J.P. [doi.org]

We describe the complex histopathologic patterns present in this case, discuss the main differential diagnoses that the surgical pathologist must consider when confronted by soft tissue ossification, and review the pertinent literature. [ncbi.nlm.nih.gov]

administration of pamidronate. ( 16532474 ) Hou J.W. 2006 23 Progressive osseous heteroplasia resulting from a new mutation in the GNAS1 gene. ( 14723729 ) Chan I....Child F.J. 2004 24 Progressive osseous heteroplasia in the face of a child. ( 12605446 [malacards.org]

Progressive osseous heteroplasia controlled by intravenous administration of pamidronate. Am J Med Genet A 2006;140:910–3. Google Scholar 21. Adegbite NS, Xu M, Kaplan FS, Shore EM, Pignolo RJ. [degruyter.com]

Jwalant Modi MS - Orthopaedics, MBBS Orthopedist - Specializes in Treatment of Progressive Osseous Heteroplasia modi hospital near samarpan tower kk nagar road prabhat chowk Ghaltodia, Ahmedabad Recently consulted for: Knee Pain, Knee Pain Treatment Book [lybrate.com]

Case 3: A 9-year-old boy with knee pain and subcutaneous ossifications in back and upper/lower extremity, causing significantly limited joint mobility. Lab tests were normal. [ncbi.nlm.nih.gov]

Case 3: A 9-year-old boy with knee Pain and Subcutaneous ossifications in back and upper/lower extremity, causing significantly limited joint mobility [19]. [gulfdoctor.net]

In April 2001, a 52-yr-old woman, with no familial history of abnormal ossification, was admitted for pain and stiffness of the lower limbs. [academic.oup.com]

She first experienced symptoms in 1985, with knee, calf and ankle pains, and later suffered from lower limb stiffness. [academic.oup.com]

She is of small stature (0.4th centile) and started to develop skin lesions at the age of 9 months. These have been confirmed histologically as osteoma cutis. She is of normal intelligence and development and has no dysmorphic features. [ncbi.nlm.nih.gov]

Biopsies of the skin lesions demonstrated osteoma cutis consistent with POH [48]. [gulfdoctor.net]

lesions: Case reports and review, Pediatric Dermatology, 36, 3, (355-359), (2019). [doi.org]

Her father and father's aunt had subcutaneous nodules. At the age of 5 years, physical examination of the patient revealed ossified subcutaneous nodules and plaques on both upper limbs, the right side was predominantly affected. [ncbi.nlm.nih.gov]

Case 1: A 4-year-old boy with obesity, speech delay, and expanding subcutaneous masses on buttock/forearm. Physical exam revealed round facies and brachydactyly. [ncbi.nlm.nih.gov]

Case 1: A 4-year-old boy with obesity, speech delay, and expanding subcutaneous masses on buttock/forearm [18]. [gulfdoctor.net]

Biopsy results from the lesions showed calcinosis cutis superficially, with both endochondral and intramembranous bone formation in the deeper tissues. [ncbi.nlm.nih.gov]

Occasional reports of mild heterotopic ossification in Albright's hereditary osteodystrophy (AHO) and a recent report of two patients with AHO who had atypically extensive heterotopic ossification suggested a common genetic basis for the two disorders [ncbi.nlm.nih.gov]

PE at age 4 months included: length and weight 95%, a round face, short 4th metacarpals, and extensive subcutaneous ossifications of the lower limbs, buttocks, and back. [ncbi.nlm.nih.gov]

face, brachydactaly, neurobehavioral abnormalities. [slideplayer.com]

[…] contractural arachnodactyly Congenital deformities of fingers Congenital deformities of limbs Congenital elbow dislocation, bilateral Congenital elbow dislocation, unilateral Congenital genu flexum Congenital genu recurvatum Congenital heart defect-round [se-atlas.de]

Subcutaneous ossifications that are superficial and well circumscribed may be surgically removed when they are large or cause local irritation, although they may recur [2]. [gulfdoctor.net]