Presentation
It can present ulceration, inflammation or even bleeding and can cause necrosis of the adjacent tissues. [orpha.net]
Presentation on theme: "Proliferating Trichilemmal Cyst Presenting as Limbal Mass Dr Pawan Prasher Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, India. [slideplayer.com]
This paper presents the diagnosis and management of one case of malignant proliferating trichilemmal cyst followed by review of the literature. [ncbi.nlm.nih.gov]
Skin
- Ulcer
The ulcer started as a hard swelling over the same site that gradually increased in size and ulcerated over a few months. The ulcer kept increasing in size despite systemic antibiotics and local care. [idoj.in]
Ulcerated PPT is an important differential diagnosis of ulcerated scalp swellings and needs to be differentiated from squamous cell carcinoma. [jdrntruhs.org]
It was initially growing slowly and later it started to ulcerate with foul smelling discharge and rapid enlargement that interfered with the patient's daily life mainly during the last 6 months. [panafrican-med-journal.com]
A 64-year-old women presented to our hospital with a recurrent ulcerated mass lesion of the scalp. Non-contrast-enhanced computed tomography scan of the head was performed. [ncbi.nlm.nih.gov]
It can present ulceration, inflammation or even bleeding and can cause necrosis of the adjacent tissues. [orpha.net]
Psychiatrical
- Aggressive Behavior
Complete excision is recommended for all benign proliferating variants owing to their potential for locally aggressive behavior and malignant transformation. [ncbi.nlm.nih.gov]
Thus, complete excision is recommended for all benign proliferating variants owing to their potential for locally aggressive behavior and malignant transformation. [e-ijd.org]
However, this case was unusual for its aggressive behavior since the tumor demonstrated involvement of multiple regional lymph nodes at presentation. [bioline.org.br]
Neurologic
- Confusion
PTC can be confused both grossly and microscopically with squamous cell carcinoma and malignant PTC. Distinction between these lesions has historically been made on a histologic basis. We present four cases of PTC. [ncbi.nlm.nih.gov]
Sanderson Medicine The British journal of dermatology 1976 The histological features of 149 trichilemmal cysts removed from sixty‐five patients are reviewed and related to the clinical findings, finding that they can be confused with a well differentiated [semanticscholar.org]
It is usually confused with squamous cell carcinoma both sharing many common features. So the identification of malignant PTT is very essential. [scienceopen.com]
The large size of the lesion and it was clinically confused with squamous cell carcinoma. [Figure 1], [Figure 2], [Figure 3], [Figure 4] Article Access Statistics Viewed 2556 Printed 31 Emailed 0 PDF Downloaded 53 Comments [Add] [e-ijd.org]
Much confusion and misconception exist among surgeons regarding the exact nature and origin of these lesions, with the cyst contents on casual observation appearing to be sebaceous in nature. [najms.org]
Workup
Progress logically from the histologic pattern, through the appropriate workup, around the pitfalls, to the best diagnosis. [books.google.de]
Treatment
Radical surgical treatment and precise histological analysis are essential in order to achieve a fast and complete healing. Cooperation of the clinician and the pathologist is essential for accurate diagnosis, treatment and follow-up planning. [ncbi.nlm.nih.gov]
Prognosis
Prognosis is good in most cases but the patient should be followed closely after surgery. [2] Last updated: 1/6/2016 [rarediseases.info.nih.gov]
What is the Prognosis of Benign Proliferating Pilar Tumor? (Outcomes/Resolutions) The prognosis for Benign Proliferating Pilar Tumor is excellent with appropriate treatment, since it is a benign cyst. [dovemed.com]
Objectives: (1) To report the incidence of cases of PTCs in a General Hospital during a 12 years period. (2) To determine the expression of ki67 using immunohistochemical staining. (3) To correlate ki67 reaction patterns with clinical prognosis. [ijtrichology.com]
Prognosis The prognosis is excellent with complete excision. Local recurrence and metastasis are extremely rare in benign cases. However, in proven malignant cases, metastasis has been suggested to occur in 30% of cases. [emedicine.medscape.com]
Etiology
Eruptive collagenomas are non familial connective tissue nevi of unknown etiology presented with an abrupt onset. While most cases are reported in young adults, there is a paucity of literature in children. [ingentaconnect.com]
[…] are believed to arise from pilar cysts; however, it remains unknown what triggers the proliferative activity (Dermatol Surg 2007;33:1102) Trauma and inflammation have been suggested as the triggers in some cases (J Dermatol Surg Oncol 1987;13:1339) Etiology [pathologyoutlines.com]
Etiology Trichilemmal carcinoma is a carcinoma of the outer root sheath. The exact etiology is unknown, but it appears to be related to actinic damage. [clinicaladvisor.com]
(Etiology) The cause of development of Benign Proliferating Pilar Tumor is unknown. [dovemed.com]
Epidemiology
Epidemiology Frequency Proliferating pilar tumor (PPT) are rare. Sex These tumors occur more commonly in females than in males. [emedicine.medscape.com]
An analytical epidemiological approach. Dermatol.Surg. 23: 1043-1046. IF 1.505 138. [user.medunigraz.at]
Pathophysiology
[…] for recurrence and metastasis Terminology Proliferating pilar cyst Proliferating trichilemmal cyst ICD coding ICD-10: L72.11 - pilar cyst ICD-11: EK70.1 - trichilemmal cyst Sites Scalp (85%), less commonly on the trunk (Am J Clin Pathol 2004;122:566) Pathophysiology [pathologyoutlines.com]
Pathophysiology A proliferating pilar tumor (PPT) usually arises in the setting of single or multiple pilar cysts. An asymptomatic nodule is often present for months to years before a rapid increase occurs in the size of the lesion. [emedicine.medscape.com]
Pathophysiology It is unknown whether trichilemmal carcinoma develops from an existing benign lesion or de novo. Few trichilemmal carcinomas show evidence of a coexisting trichilemmoma. [clinicaladvisor.com]
Prevention
Adjuvant chemotherapy and radiotherapy have been used to prevent recurrence in MPTT. [3] Our patient received adjuvant radiotherapy and has been kept under close follow-up. [jpgmonline.com]
In a case study of malignant proliferating pilar tumor (PPT) with multinodal metastasis, wide local excision with 1-cm margins was performed, followed by adjuvant chemotherapy and radiation to prevent recurrence. [28] Of note, in 2017 a case report described [emedicine.medscape.com]