Presentation
It can present ulceration, inflammation or even bleeding and can cause necrosis of the adjacent tissues. [orpha.net]
This paper presents the diagnosis and management of one case of malignant proliferating trichilemmal cyst followed by review of the literature. [ncbi.nlm.nih.gov]
Presentation on theme: "Proliferating Trichilemmal Cyst Presenting as Limbal Mass Dr Pawan Prasher Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, India. [slideplayer.com]
Entire Body System
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Weight Loss
She had no history of weight loss, gastrointestinal complaints, breathlessness, nausea, vomiting and recurrent fever. She had no eye complaints. [idoj.in]
Skin
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Subcutaneous Mass
Characteristic findings on physical examination On physical examination, PTT can be smooth dermal to subcutaneous masses or exophytic to fungating. Ulceration is sometimes present, with foul-smelling drainage of keratinous material (Figure 1). [dermatologyadvisor.com]
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Anhidrosis
Rosacea ( Perioral dermatitis, Rhinophyma ) Follicular cysts Epidermoid cyst · Trichilemmal cyst · Sebaceous cyst · Steatocystoma multiplex Inflammation Pseudofolliculitis barbae · Hidradenitis suppurativa · Folliculitis Sweat glands eccrine ( Miliaria, Anhidrosis [wikidoc.org]
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Acneiform Eruption
eruption ( Acne vulgaris, Chloracne, Blackhead ) · Rosacea ( Perioral dermatitis, Rhinophyma ) Follicular cysts Epidermoid cyst · Trichilemmal cyst · Sebaceous cyst · Steatocystoma multiplex Inflammation Pseudofolliculitis barbae · Hidradenitis suppurativa [wikidoc.org]
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Koilonychia
10.1002/1097-0142(19810901)48:5 3.0.CO;2-1. 8.0 8.1 8.2 8.3 8.4 8.5 "Dermatology Atlas". v t e Disorders of skin appendages ( L60-75, 700-709 ) Nail thickness: Onychogryphosis · Onychauxis color: Beau's lines · Yellow nail syndrome · Leukonychia shape: Koilonychia [wikidoc.org]
Workup
Progress logically from the histologic pattern, through the appropriate workup, around the pitfalls, to the best diagnosis. [books.google.de]
Treatment
Radical surgical treatment and precise histological analysis are essential in order to achieve a fast and complete healing. Cooperation of the clinician and the pathologist is essential for accurate diagnosis, treatment and follow-up planning. [ncbi.nlm.nih.gov]
Prognosis
Prognosis is good in most cases but the patient should be followed closely after surgery. [2] Last updated: 1/6/2016 [rarediseases.info.nih.gov]
Objectives: (1) To report the incidence of cases of PTCs in a General Hospital during a 12 years period. (2) To determine the expression of ki67 using immunohistochemical staining. (3) To correlate ki67 reaction patterns with clinical prognosis. [ijtrichology.com]
[…] become malignant 11 Conclusions Proliferating trichilemmal cyst can present as a gradually progressing limbal mass It is a benign condition that needs to be distinguished from malignant squamous cell carcinoma which has similar presentation but different prognosis [slideplayer.com]
(A series of 63 cases of PTT showing an overall good prognosis and low recurrence rate with wide local excision.) Satyaprakash, AK, Sheehan, DJ, Sangueza, OP. “Proliferating trichilemmal tumors: A review of the literature”. [dermatologyadvisor.com]
Their correct recognition has an impact on treatment, outcome, and prognosis [2], [4], [5] and can prevent a therapeutic misadventure. References 1. Erdem H, Yildirim U, Uzunlar AK, Sahiner C, Ozcelik D, TopluG. [ijdvl.com]
Etiology
The granulomatous lymphadenitis was presumed to be of tubercular etiology in an Indian patient, despite a failure to demonstrate bacilli in the tissue. [ijdvl.com]
Eruptive collagenomas are non familial connective tissue nevi of unknown etiology presented with an abrupt onset. While most cases are reported in young adults, there is a paucity of literature in children. [ingentaconnect.com]
Etiology Trichilemmal carcinoma is a carcinoma of the outer root sheath. The exact etiology is unknown, but it appears to be related to actinic damage. [clinicaladvisor.com]
(Etiology) The cause of development of Malignant Proliferating Pilar Tumor is unknown. [dovemed.com]
Epidemiology
Epidemiology Frequency Proliferating pilar tumor (PPT) are rare. Sex These tumors occur more commonly in females than in males. [emedicine.medscape.com]
An analytical epidemiological approach. Dermatol.Surg. 23: 1043-1046. IF 1.505 138. [user.medunigraz.at]
Pathophysiology
Pathophysiology A proliferating pilar tumor (PPT) usually arises in the setting of single or multiple pilar cysts. An asymptomatic nodule is often present for months to years before a rapid increase occurs in the size of the lesion. [emedicine.medscape.com]
Pathophysiology It is unknown whether trichilemmal carcinoma develops from an existing benign lesion or de novo. Few trichilemmal carcinomas show evidence of a coexisting trichilemmoma. [clinicaladvisor.com]
Prevention
Their correct recognition has an impact on treatment, outcome, and prognosis [2], [4], [5] and can prevent a therapeutic misadventure. References 1. Erdem H, Yildirim U, Uzunlar AK, Sahiner C, Ozcelik D, TopluG. [ijdvl.com]
Simple trichilemmal cysts are often easily enucleated, in contrast to proliferating trichilemmal cysts, which require wide local excision to prevent recurrence. 1 Because of the malignant potential of proliferating trichilemmal cysts, management includes [ajnr.org]
Currently, there are no known methods available to prevent the occurrence of Malignant Proliferating Pilar Tumors Regular medical screening at periodic intervals with blood tests, scans, and physical examinations, are mandatory, due to its metastasizing [dovemed.com]
Consequently the surgical treatment performed comprised wide local excision with 1 cm margin of normal tissue to prevent recurrence, as suggested in the latest publication. [20] Consequently, we believe that the ki67 reaction patterns are in fact directly [ijtrichology.com]