Case #2: A 31-year-old male presented with sudden occipital, neck, right shoulder and back pain. He was neurologically intact. MRI and angiogram showed a predominantly right sided arteriovenous malformation. [ncbi.nlm.nih.gov]

In this section, the impact of the study drugs on ERP measures of recollection, which occur in the parietal region 400–600 ms after picture presentation, is presented. [dx.doi.org]

• Intravenous Administration

  Emulsions represent complex formulation compositions whose suitability for intravenous administration is dependent on a number of factors. [ncbi.nlm.nih.gov]

  To prevent that pain, anesthesiologists will often an inject a local anesthetic like lidocaine before the intravenous administration of propofol, she said. [health.harvard.edu]

  The main purpose of this study was to compare patients’ subjective tolerance, recovery of brain function and safety of use after intravenous administration of propofol and midazolam by bolus during FB, using the bispectral index (BIS) as an objective [erj.ersjournals.com]

• Intravenous Drugs

  Propofol is an intravenous drug used commonly for the induction and maintenance of anesthesia. It is also used for sedation for non-surgical procedures and for patient intensive care. [thesun.co.uk]

  Case 2 A 36 year old man with history of psychotic illness attributed to longstanding alcoholic and intravenous drug misuse came to the emergency room with right leg cellulitis. [emj.bmj.com]

  It is well known that patients with advanced oncological and haematological disease, including solid organ and bone marrow transplantation, intravenous drug users and HIV patients, have a higher incidence of complications during bronchoscopy [ 23 ]. [erj.ersjournals.com]

• Splenectomy

  Case 3 A 32-year-old female patient had an emergency splenectomy after a traffic accident. [doi.org]

  Not Available CompletedTreatment Rupture of Anterior Cruciate Ligament / Tear of Anterior Cruciate Ligament 1 Not Available CompletedTreatment Sedation therapy 1 Not Available CompletedTreatment Sepsis / Shock 1 Not Available CompletedTreatment Status;Splenectomy [drugbank.ca]

• Developmental Delay

  Children with cognitive impairment or developmental delay were not excluded. [web.archive.org]

• Turkish

  Erkman Sanri, Sinan Karacabey, Haldun Akoglu, Bora Kaya and Ozlem Guneysel, Comparison of ketamine/propofol (ketofol) and etomidate/fentanyl (etofen) combinations for procedural sedation and analgesia in the emergency department: An observational study, Turkish [doi.org]

• Tonsillar Hypertrophy

  Exclusion criteria were ASA status ≥III, severe pulmonary or cardiovascular disease, anatomic airway abnormalities or extreme tonsillar hypertrophy, a history of propofol intolerance, known fat metabolism disorder, and diagnostic imaging for acute trauma [web.archive.org]

• Hemoptysis

  We report a case of a 23-year-old healthy male who developed acute cough, hemoptysis and hypoxia following administration of propofol for splinting of a foot fracture. Chest radiography showed bilateral patchy infiltrates. [ncbi.nlm.nih.gov]

• Acute Cough

  We report a case of a 23-year-old healthy male who developed acute cough, hemoptysis and hypoxia following administration of propofol for splinting of a foot fracture. Chest radiography showed bilateral patchy infiltrates. [ncbi.nlm.nih.gov]

• Torticollis

  Here we present a case of a 17-year-old boy with ulcerative colitis who presented with ballismus, torticollis, tongue thrusting, and oculogyric movements after colonoscopy under general anesthesia with propofol. [ncbi.nlm.nih.gov]

• Seizure

  […] the seizure, and any other possible triggers for the reaction such as other drugs used, including premedication; post seizure investigations including temperature, blood sugar, electrolytes, arterial gas analysis, neurological examination, EEG and CT [ncbi.nlm.nih.gov]

  These movements may include: dystonia chorea athetosis twitches opisthotonus Abnormal movements may mimic tonic and clonic movements during seizures, especially during the postoperative period. 76 In several cases, cortical epilepsy was activated during [epilepsy.com]

• Lower Extremity Spasticity

  Following a propofol anesthetic, a 5-year-old girl with lower extremity spasticity seized and developed hypertriglyceridemia, hyperkalemia, and metabolic acidosis. [ncbi.nlm.nih.gov]

• Extrapyramidal Symptoms

  Extrapyramidal symptoms are an uncommon but well-recognized side effect after the administration of general anesthesia in patients without a significant neurologic history. [ncbi.nlm.nih.gov]

• Colitis

  Here we present a case of a 17-year-old boy with ulcerative colitis who presented with ballismus, torticollis, tongue thrusting, and oculogyric movements after colonoscopy under general anesthesia with propofol. [ncbi.nlm.nih.gov]

  […] and response, age, weight, clinical status (e.g., ASA physical status, degree of debilitation), blood lipid profile, underlying pathologic conditions (e.g., shock, intestinal obstruction, malnutrition, anemia, burns, advanced malignancy, ulcerative colitis [web.archive.org]

A total of 22 metabolites were detected varied after propofol posthypoxia treatment. [ncbi.nlm.nih.gov]

Priapism: a three-phase concept of management according to aetiology and prognosis. Br J Urol 1986 ;58: 113 – 8. Google Scholar | Crossref | Medline 5. van Arsdalen, KN, Chen, JW, Smith, MJ. Penile erections complicating transurethral surgery. [dx.doi.org]

As Joan Rivers ’ prognosis grows more dire each day, RadarOnline.com has learned that medical investigators are growing ever closer to uncovering the real reason the healthy 81-year-old was sent spiraling into a coma after a standard medical procedure [radaronline.com]

In Diamond’s case, it would be helpful to have an interdisciplinary team meeting to clarify her prognosis and goals of care. [pediatrics.aappublications.org]

CONCLUSION: We report a case of hypertriglyceridemia independent propofol induced pancreatitis possibly related to an idiosyncratic reaction and propose that this drug to be reassigned as a class Ia drug as an etiologic factor for acute pancreatitis. [ncbi.nlm.nih.gov]

Our limited knowledge on the etiology and pathophysiology of PRIS preclude effectively preventing its occurrence. High doses and long-term infusion are the main risk factors. [n.neurology.org]

At five of seven hospitals, an etiologic agent was isolated from the case patients ( Table 4 ). [nejm.org]

Evaluation of the patient's medical history and drug profile allowed us to exclude possible etiologies of green urine, such as methylene blue, indigo, biliverdin, medicines or infection. [omicsonline.org]

In: Program and abstracts of the 2nd Annual Meeting of the Society for Hospital Epidemiology of America, Baltimore, April 12–14, 1992. West Deptford, N.J.: Society of Hospital Epidemiology of America, 1992. abstract. 41. [nejm.org]

Chen MD Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, GA, USA Division of Infectious Disease Epidemiology, Pennsylvania Department of Health, Harrisburg, PA, USA Search [dx.doi.org]

The epidemiology of propofol abuse is unfamiliar to most of the anesthesia providers. Propofol generally has not been listed as a controlled substance. [journals.lww.com]

Solís Herruzo Department of Gastroenterology. 1 Department of Epidemiology. Hospital Unviersitario 12 de Octubre. [scielo.isciii.es]

Risk of bias and methodological appraisal practices in systematic reviews published in anaesthetic journals: a meta-epidemiological study. Anaesthesia. 2016;71:955–68. View Article Google Scholar Berning V, Laupheimer M, Nübling M, Heidegger T. [bmcanesthesiol.biomedcentral.com]

Her brain magnetic resonance imaging (MRI) and computed tomography (CT) scans reveal prominent bilateral brain lesions, matching with the proposed pathophysiologic mechanism of the syndrome. [ncbi.nlm.nih.gov]

Our limited knowledge on the etiology and pathophysiology of PRIS preclude effectively preventing its occurrence. High doses and long-term infusion are the main risk factors. [n.neurology.org]

Aetiology and pathophysiology PRIS is thought to be secondary to an imbalance between energy demand and utilization caused by impairment of mitochondrial oxidative phosphorylation and free fatty acid utilization, ultimately leading to lactic acidosis [academic.oup.com]

Iaizzo, Pathophysiologic and anesthetic considerations for patients with myotonia congenita or periodic paralyses, Pediatric Anesthesia, 23, 9, (824-833), (2013). Žiga Hodnik, Tihomir Tomašić, Lucija Peterlin Mašič, Fiona Chan, Robert W. [doi.org]

Atlanta, GA, USA Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA Centers for Disease Control and Prevention, 1600 Clifton Rd MS‐A35, Atlanta, GA 30333, USA. [dx.doi.org]

BACKGROUND: Preconditioning is one of the most powerful mechanisms preventing the myocardial ischemic damage that occurs during coronary artery bypass grafting. [ncbi.nlm.nih.gov]

[…] substance that can react readily with, and thereby eliminate, radicals. intravenous anaesthetic sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. antiemetic A drug used to prevent [ebi.ac.uk]

Research Prevention of pain on... [bmj.com]