We present a case of RMS prostate in a young adult presenting as BOO. Case Report A 19-year-old boy presented with one month’s history of dysuria and increased frequency of urination followed by acute urinary retention. [ncbi.nlm.nih.gov]

• Splenomegaly

  He also had scattered crackles all over the chest, mild splenomegaly and non-tender prostate enlargement. Investigations showed normocytic normochromic anemia, hypercalcemia and hyperuricemia. Routine urinalysis was normal. [casesjournal.biomedcentral.com]

• Pelvic Mass

  Embryonal rhabdomyosarcoma of the prostate in a 19 year old Posted by: Philip Alex | Posted on: May 27th, 2006 | 0 Comments A 19 year old boy presented to us with edema, difficulty in passing urine and a pelvic mass extending till the umbilicus. [manalihospital.com]

  Prostate tumors Prostate tumors produce large pelvic masses, sometimes with urethral strangury and constipation. Tend to occur in infants and in older age groups. Prostate tumors have a greater tendency to infiltrate adjacent tissues (than bladder). [pedsoncologyeducation.com]

  It is characterized by a high degree of aggressiveness, rapid local growth with the formation of large pelvic masses, often leading to urethral obstruction, and systemic spread, commonly to the lungs, liver, and bone. [ccij-online.org]

• Hematuria

  We treated a rare case of spindle cell variant of embryonal rhabdomyosarcoma (RMS) of the prostate of a patient referred to our hospital for gross hematuria. [ncbi.nlm.nih.gov]

  A 22 years old male patient presented with hematuria and acute urinary retention was referred to the hospital with symptoms of suprapubic pain, hematuria, CBD dependent, decreased hemoglobin and hematocrit levels. [article.sapub.org]

  The patient complains of the difficulty of urinating and hematuria one month after falling. We underwent drainage of the swelling area, found pus 100cc and took a sample for pathological examination. The result was embryonal rhabdomyosarcoma. [e-journal.unair.ac.id]

  The authours recently experienced two cases of rhabdomyosarcomas of the prostate in 35-year-old and 51-year-old males who had suffered from gross hematuria and difficulty of urination. [jpatholtm.org]

• Prostatic Mass

  The CT findings in the prostatic tumors included an enlarged, inhomogeneous prostatic mass with invasion of the perirectal fat. [journals.lww.com]

  The prostatic acid phosphatase (PAP) were also within normal limits.Computed tomography of prostate showed homogenous soft tissue mass measuring 4x5cm in size (Figure 1). [peertechz.com]

  After chemotherapy completion, CT and CT/PET showed a complete remission of pulmonary disease and partial response of the prostate mass. [ncbi.nlm.nih.gov]

• Enlargement of the Prostate

  Digital rectal examination showed a rather smooth but enlarged prostate without palpable tumor mass. Ultrasound scan showed homogeneous prostate tissue and an enlarged volume of approximately 50–60 cm3. The clinical diagnosis was prostate adenoma. [ncbi.nlm.nih.gov]

  […] hypertrophy of the prostate benign prostatic hypertrophy BPH enlarged prostate nodular prostate polyp of prostate Type 1 Excludes benign neoplasms of prostate (adenoma, benign) (fibroadenoma) (fibroma) (myoma) ( D29.1 ) Type 2 Excludes malignant neoplasm [icd10data.com]

Diagnosing rhabdomyosarcoma requires a careful and complete medical workup and examination of your child. [chop.edu]

The workup of these tumors typically includes the following studies: CT and MRI scans of affected region(s). Chest x-ray or CT scan of chest. Bone scan. Bone marrow biopsy. For genitourinary location: Cystoscopy (scope to look inside the bladder). [oncolink.org]

[…] resonance imaging (MRI) Bone scanning Ultrasonography Echocardiography Biopsy Open or core needle biopsy: To obtain tissue sampling for diagnosis and molecular studies Bone marrow aspiration and biopsy: To assess for metastatic spread to bone marrow See Workup [emedicine.medscape.com]

Pediatric Rhabdomyosarcoma Medscape Referenced article by Timothy Cripe MD, covering background, presentation, diagnosis, workup, treatment and follow-up. [cancerindex.org]

During treatment for acute lymphatic leukemia at the age of 6 years, the patient had been exposed to a cumulative radiation dose of 10 Gy across his entire body. [ncbi.nlm.nih.gov]

Intensive chemotherapy as primary treatment for rhabdomyosarcoma of the pelvis. [jpedsurg.org]

1 Patterns of failure and toxicity profile following proton beam therapy for pediatric bladder and prostate rhabdomyosarcoma. 61 31397065 2019 2 Current treatment of pediatric bladder and prostate rhabdomyosarcoma (bladder preserving vs. radical cystectomy [malacards.org]

Three patients had an unsuccessful treatment attempt with sildenafil. 8 patients, including the three failures of oral PDE-5-inhibitors, were successfully treated with intracavernous injection of Alprostadil (mean post treatment SIEF-NS=38.25). [spuonline.org]

Commonly used terms in treatment Back to top Side effects Side effects and complications of treatment Treatment often causes side effects and these will be discussed before treatment starts. [childrenwithcancer.org.uk]

Prognosis is related to histologic type and tumor stage. Alveolar RMS has poorer prognosis. In contrast to pediatric RMS, adult RMS does not appear to respond to multimodal therapy and has a poorer prognosis. [auanet.org]

In adults prognosis is very poor, therefore early diagnosis is crucial. To date, only three cases of spindle cell subtype of embryonal rhabdomyosarcoma of the prostate in an adult have been published. [ncbi.nlm.nih.gov]

In contrast to the relatively good prognosis for treated rhabdomyosarcoma in children, the prognosis in adults is poor with most dying of disease in <2 years, despite multimodality therapy. [peertechz.com]

Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]

Etiology The cause of rhabdomyosarcoma is unknown, but a translocation t(2;13) is very often associated with the alveolar type. Diagnostic methods Diagnosis is based on positive muscular markers and immunohistochemistry. [orpha.net]

Etiology of Prostate Sarcoma Li-Fraumeni syndrome: Li-Fraumeni syndrome is associated with mutation of the p53 suppressor gene: this leads to children with sarcoma whose mothers have a high risk of breast cancer and siblings with an increased cancer risk [urology-textbook.com]

Back to 2016 Fall Congress Pediatric Bladder and Prostatic Sarcomas: A Surveillance, Epidemiology, and End Results (SEER) Analysis Casey A. Seideman, MD, Andrew Jacobs, MD, Lane S. Palmer, MD, Richard Glick, MD. [fallcongress.spuonline.org]

Essential features Small round cell to spindle cell tumor, variable cellularity Occurs in young patients and requires aggressive treatment Epidemiology Most common prostatic malignancy in children / infants Clinical features Firm, smooth enlargement of [pathologyoutlines.com]

It covers relevant literature by leading experts in basic science, molecular biology, epidemiology, cancer prevention, cellular imaging, staging, treatment, targeted therapeutics and innovative technologies. [books.google.ro]

Summary Epidemiology The annual incidence is 1/170,000. In children younger than 15 years, the annual incidence is estimated at 1/244,000. Clinical description The median age of diagnosis is 5 years. [orpha.net]

It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. [books.google.com]

Internal Medicine (477) Paediatrics, Neonatology (424) Pathology and Forensic Medicine (323) Neurology (308) Physiology and Pathophysiology (276) Genetics (255) Surgery, Traumatology and Orthopaedics (219) Medical Chemistry and Biochemistry (216) Infectology [portal.mefanet.cz]

The National Rosacea Society Expert Committee updated its guidelines in 2017 on standard classification and pathophysiology of rosacea. [ncbi.nlm.nih.gov]

Standard classification and pathophysiology of rosacea: The 2017 update by the National Rosacea Society Expert Committee. Journal of the Academy of Dermatology. 2017;78:148. Briggs JK. Facial skin problems. In: Triage Protocols for Aging Adults. [mayoclinic.org]

Treating allergies Avoiding cosmetics and skin products that cause allergic reactions can prevent a reddened nose. [medicalnewstoday.com]

Prevention Rhabdomyosarcoma can't be prevented. In rare cases, it's possible that a family history of cancer at a young age may increase the risk of RMS, but RMS is not inherited. And there is no known link to any lifestyle or environmental issues. [mayoclinic.org]

There’s no known way to prevent rhinophyma. However, some factors can increase blood flow to the surface of your skin and aggravate rosacea symptoms. [healthline.com]