We present a case of a 35-year-old male with a history of hypercoagulability and St. [ncbi.nlm.nih.gov]

• Fever

  Case 2 was a 79-year-old woman presenting with fever 40 days after aortic valve replacement with a bioprosthesis. [ncbi.nlm.nih.gov]

  Figure 1 A 77-year-old man presented with a two-month history of fever, chills, and malaise. Three months earlier, he had undergone valve replacement for calcific aortic stenosis at another institution. [nejm.org]

  The fever decreased but persisted at a level of 37.8°C. [bmcinfectdis.biomedcentral.com]

• Pertussis

  B. holmesii, a strictly aerobic, small, Gram-negative coccobacillus, has been implicated as an infrequent cause of a pertussis-like syndrome and other respiratory illnesses. [ncbi.nlm.nih.gov]

• Heart Disease

  […] of the heart valves Valvulopathy, or heart valve disease, arising in a transplanted heart Rheumatoid vascular disease Congestive heart disease Mitral valve prolapse Age-related degenerative heart disease Heart disease due to underlying connective tissue [dovemed.com]

  Disease 502 The Heart and Pregnancy 537 Chapter32 Women and Heart Disease 553 The Elderly and Aging 561 Chapter34 EndofLife Care 587 The Heart and Other Organ Systems 595 Chapter 35B Hematologic Disorders and the Heart 604 Chapter35C The Heart and the [books.google.com]

  Acute Heart Failure, Interventions and Structural Heart Disease Keywords: Anti-Bacterial Agents, Cardiac Surgical Procedures, Cardiopulmonary Bypass, Edema, Endocarditis, Endocarditis, Bacterial, Heart Failure, Heart Valve Diseases, Pulmonary Edema, [acc.org]

  Diseases listed under high risk include: Prior endocarditis Unrepaired cyanotic congenital heart diseases Completely repaired congenital heart disease in their first 6 months Prosthetic heart valves Incompletely repaired congenital heart diseases Cardiac [en.wikipedia.org]

  Experience of the Veterans Affairs Cooperative Study on Valvular Heart Disease. J Thorac Cardiovasc Surg. 1994; 108 (2): 207-14[ PubMed ] 8. Sett SS, Hudon MP, Jamieson WR, Chow AW. Prosthetic valve endocarditis. [jjmicrobiol.com]

• Heart Murmur

  Prominent clinical features include fever, new or changing heart murmurs, leukocytosis, anemia and hematuria. The etiologic microorganism can be isolated in more than 90% of all cases. [ncbi.nlm.nih.gov]

  murmur: It is an abnormal heart sound that can be listened with a stethoscope Electrical abnormalities in the heart (cardiac arrhythmias) Stroke: It is a condition in which blood supply to an area of the brain is disrupted that results in a weakness [dovemed.com]

  The most common clinical features are fever, major peripheral emboli, and a changing heart murmur. Less frequently, the patients present focal or generalized neurologic deficits, heart failure or dyspnea. [cureus.com]

  Heart murmurs are found in up to 85% and new murmurs have been recently reported in 48% of patients. [patient.info]

  Specialty Cardiology, Infectious disease Symptoms Fever, small areas of bleeding into the skin, heart murmur, feeling tired, low red blood cells [1] Complications Valvular insufficiency, heart failure, stroke, kidney failure [2] [1] Causes Bacterial infection [en.wikipedia.org]

• Systolic Murmur

  Examination revealed a temperature of 40°C and a systolic murmur in the aortic area. [ncbi.nlm.nih.gov]

  Oral temperature was 37.6°C, mechanical heart sounds were heard, as well as a 2/6 apical systolic murmur. The physical examination was otherwise unremarkable. [springerplus.springeropen.com]

  Physical examination revealed fever, a splinter hemorrhage, and an ejection systolic murmur. [wwwnc.cdc.gov]

• Diastolic Murmur

  On physical examination the patient was pale and presented with bilateral lower limb edema, jugular distension and a grade II/IV diastolic murmur on the left sternal border. [elsevier.pt]

• Blood Culture Positive

  positive for infectious organisms Blood cultures that are positive for microorganisms, which are taken 12 hours apart 3 blood cultures positive on separate occasions that are taken at least 1 hour apart Abnormalities in echocardiogram showing either a [dovemed.com]

  Microorganisms consistent with IE from 2 persistely positive blood cultures: At least 2 positive blood cultures of blood samples drawn > 12h apart or all of 3 or a majority of ≥ 4 separate cultures of blood with first & last sample drawn at least 1h apart [wikiecho.org]

Data concerning clinical characteristics, treatment, and outcome were registered. [ncbi.nlm.nih.gov]

Fungal prosthetic valve endocarditis is an extremely severe form of infective endocarditis, with poor prognosis and high mortality despite treatment. [ncbi.nlm.nih.gov]

It has a bad prognosis and high morbidity and mortality due to cardiac or extracardiac complications. 1-3 It is often managed by heart surgery 2,4,5 and numerous studies indicate that the prognosis of patients with PVE is better using a combined medical-surgical [revespcardiol.org]

Abstract Fungal prosthetic valve endocarditis is an extremely severe form of infective endocarditis, with poor prognosis and high mortality despite treatment. [elsevier.pt]

A literature review revealed 646 cases of PVE with an identified etiology, of which 264 (41%) were caused by coagulase-negative staphylococci and 43 (7%) by Streptococcus spp. This is in agreement with the current study findings. [ncbi.nlm.nih.gov]

The predominant etiologic agents are bacteria followed by fungi. Fungal endocarditis (FE) is an uncommon occurrence and the most severe form of IE. [omicsonline.org]

Candida albicans is the most common etiological agent for this rare but increasingly frequent condition. [elsevier.pt]

In addition, a 5-year outlook offers consolidated knowledge on epidemiological trends of both culprit organisms and population subgroups suffering (and projected to suffer) from PVE. [ncbi.nlm.nih.gov]

In this review, changes in epidemiology, microbiology, diagnosis and therapy that have evolved in the past few years are analyzed. [journals.lww.com]

CRC Press, ١٣‏/٠٣‏/٢٠٠٧ - 388 من الصفحات The first up-to-date source on the subject in more than a decade, this authoritative and all-encompassing guide summarizes the latest findings on the epidemiology, pathogenesis, pathophysiology, clinical manifestations [books.google.com]

Early infection ( Microbiology: Staph aureus (40%) Coag neg staph (20%) Cx neg (20%) Fungal (10% Late infection: pathophysiology more similar to native valve endocarditis (adherence to platelet-fibrin thrombi on valve), as foreign material has become [errolozdalga.com]

This case demonstrates that carefully weighing the risks and benefits of continuing anticoagulation is essential in preventing poor outcomes. [ncbi.nlm.nih.gov]

Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. ‏ [books.google.com]