She had progressive renal dysfunction, proteinuria, corneal opacity, anemia and an abnormal lipid profile. [ncbi.nlm.nih.gov]

Study endpoints were CKD progression ( 50% eGFR loss or initiation of dialysis), cardiovascular events, and all-cause death. RESULTS: In total, 927 patients who were followed for 6 months were included in the analysis. [ncbi.nlm.nih.gov]

Heavy proteinuria (excretion of more than four grams of protein per day) indicates serious kidney disease and usually produces symptoms, in particular frothy urine. Severe proteinuria can result in protein wasting and renal damage. [britannica.com]

Keywords Urine foam; Urine froth; Chronic kidney disease; Proteinuria Introduction Foamy or frothy urine is often associated with proteinuria. [transbiomedicine.com]

A 55-year-old man of Indian descent, presented to the emergency department with a 2-year history of passing 'milky' white urine, associated with dysuria, urinary retention, bilateral flank pain and 15 kg weight loss. [ncbi.nlm.nih.gov]