Presentation
We report a 63-year-old man with well-controlled type 2 diabetes mellitus and hypertension, who presented with new onset nephrotic proteinuria and rapid deterioration in renal function. [ncbi.nlm.nih.gov]
Eyes
-
Corneal Opacity
She had progressive renal dysfunction, proteinuria, corneal opacity, anemia and an abnormal lipid profile. [ncbi.nlm.nih.gov]
Psychiatrical
-
Loss of Initiative
Study endpoints were CKD progression ( 50% eGFR loss or initiation of dialysis), cardiovascular events, and all-cause death. RESULTS: In total, 927 patients who were followed for 6 months were included in the analysis. [ncbi.nlm.nih.gov]
Urogenital
-
Bilateral Flank Pain
A 55-year-old man of Indian descent, presented to the emergency department with a 2-year history of passing 'milky' white urine, associated with dysuria, urinary retention, bilateral flank pain and 15 kg weight loss. [ncbi.nlm.nih.gov]
Workup
Persistence of significant proteinuria after resolution of the infection prompted biochemical and genetic workup which led to the diagnosis of Dent-2 disease. [ncbi.nlm.nih.gov]
The patient was then referred by the obstetrician to the nephrology clinic for a diagnostic workup. The patient reported that no blood test nor urinalysis was performed before the eighth week. [journals.sagepub.com]
This approach, however, is dependent on individual experience and not suitable for the routine workup of a large number of patients. [clinchem.aaccjnls.org]
Office workup of proteinuria: Am. J. Med. Sci. 320 : 188, 2000. [pathguy.com]
Treatment
All patients received conventional and symptomatic treatment. In addition, patients in the treatment and control groups were given YQSR (200 mL, twice per day, orally) and losartan (50 mg/d orally), respectively for 6 months. [ncbi.nlm.nih.gov]
Prognosis
For diabetic patients, distinguishing nondiabetic renal disease (NDRD) from diabetic nephropathy (DN) is important in choosing treatment modalities and determining renal prognosis. [ncbi.nlm.nih.gov]
Etiology
The aim of this study was to evaluate prevalence, etiology, and outcome of proteinuria during the follow-up of children with renal transplantation. [ncbi.nlm.nih.gov]
Protein losses of over 2000mg/24 hours in adults and over 40 mg/24 hours in children usually indicates a glomerular etiology. Preeclampsia (toxemia of pregnancy) causes massive loss of protein in the urine. [rnceus.com]
Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. [icd10data.com]
Etiology Causes can be categorized by mechanism. The most common causes of proteinuria are glomerular disorders, typically manifesting as nephrotic syndrome (see Table: Causes of Proteinuria ). [merckmanuals.com]
Epidemiology
Author information 1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. 2 Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China. 3 Beijing Municipal [ncbi.nlm.nih.gov]
The volume will cover the epidemiological studies which show that albuminuria is a strong and independent marker of kidney disease progression and cardiovascular events, the molecular details of albumin handling in the kidney at the level of the glomerulus [books.google.ro]
[…] data and RCT.3 Despite ample evidence in biological plausibility and epidemiological data, there are limitations in RCT regarding the validity of proteinuria or albuminuria as a surrogate end‐point.3 Table 1. [onlinelibrary.wiley.com]
Pathophysiology
This volume provides a comprehensive overview of the renal handling of albumin – from basic mechanisms to the pathophysiology of proteinuric diseases. [books.google.ro]
However, the pathophysiology of these associations is debated. In chronic kidney disease (CKD), phosphate retention participates in cardiovascular events and increased cardiovascular mortality. [ncbi.nlm.nih.gov]
The pathophysiologic mechanisms of proteinuria can be classified as glomerular, tubular or overflow ( Table 2 7 ). [aafp.org]
Prevention
This is a post hoc analysis of the renal substudy of the CSPPT (China Stroke Primary Prevention Trial). [ncbi.nlm.nih.gov]