Presentation
Source: Aditi Murthy, MD A 3-year-old female presented to urgent care with a 1-week history of a pruritic rash on the legs and torso. On the day of her presentation, she additionally developed two new dark brown marks on her right cheek. [healio.com]
We present a case of a female patient with Hodgkin’s lymphoma who presented with classic findings for FE after initiation of chemotherapy. [cureus.com]
A heavily pregnant woman presents with a risky rash. What is the best management? Dr Jim Newcombe 13th February 2018 0 Comments Jess, a 35-year-old woman, presents to her GP at 39 +1 weeks’ gestation in her first pregnancy. [howtotreat.com.au]
Treatment prior to presentation included diphenhydramine, cetirizine, and a 20-mg dose of prednisone without improvement. The patient was otherwise healthy with normal development and growth. [jamanetwork.com]
SOAP for Pediatrics features over 70 clinical problems with each case presented in an easy to read 2-page layout. Each step presents information on how that case would likely be handled. [books.google.de]
Workup
Workup revealed dermatitis herpetiformis (DH) and subclinical celiac disease. [mayoclinic.pure.elsevier.com]
Erythematous, pruritic rash Keywords: Pediatric, Pediatrics, Child, Integumentary, Dermatology, Immune, Infectious, Tinea corporis, Ringworm, Rash, Integumentary/Dermatology Video Features: Vitals & Demographics Differential Diagnosis & Patient Workup [reeldx.com]
The presence of her diffuse rash along with a pulmonary cavitary lesion prompted infectious workup. [cureus.com]
Appropriate laboratory workup should be done to rule out systemic disease, and occasionally a skin biopsy is warranted if the diagnosis is uncertain. [consultant360.com]
Microbiology
- Rickettsia Prowazekii
Serologic studies (IgG and IgM) for dengue virus, Rickettsia rickettsii, Rickettsia typhi, Rickettsia prowazekii, and Leptospira (total antibody), were obtained and returned negative. [academic.oup.com]
Treatment
AB - A 56-year-old man sought treatment after a vacation for an intensely pruritic skin eruption involving the buttocks. On physical examination, annular plaques were noted. [mayoclinic.pure.elsevier.com]
Treatment of diagnoses Treatment varies according to the suspected underlying cause of the rash. [bestessayhelp.com]
Treatment with both topical and systemic steroids was ineffective. Following a living nonrelated renal transplant and removal of the catheter the rash and eosinophilia resolved. [ncbi.nlm.nih.gov]
Peplomycin, a bleomycin analogue used in the treatment of prostate cancer, breast cancer, and HL, can also cause FE [7, 8]. [cureus.com]
A skin biopsy may be appropriate if the provisional diagnosis is not clear or if the condition is refractory to treatment. Management Treatment of prurigo can be difficult. The first step is focused on preventing ongoing skin picking and scratching. [medicinetoday.com.au]
Prognosis
The four clinical variants of adult T-cell leukemia–lymphoma — acute, lymphomatous, chronic, and smoldering — affect the clinical presentation and prognosis. [blogs.nejm.org]
[…] and anakinra. [5], [6] Acute pulmonary embolism manifested by our patient is a rare, life-threatening complication of adult-onset Still's disease. [7] Lee et al. have noted that adult-onset Still's disease associated with persistent rash has a poor prognosis [ijdvl.com]
Pregnancy-Related Dermatoses That Cause Pruritus Condition Synonyms Timing Features Important considerations Prognosis Atopic eruption of pregnancy Prurigo, early-onset prurigo, pruritic folliculitis, or eczema of pregnancy; prurigo gestationis Second [aafp.org]
In severe cases clonal T-cell populations can be detected in the blood or bone marrow and the prognosis is worse.3 Drug rash Drug hypersensitivity induced rashes are the commonest cause of new onset rashes in inpatients. [gmjournal.co.uk]
Etiology
The exact etiology of pruritic folliculitis is unknown. [aafp.org]
If blisters are present, one should have a higher degree of suspicion for a different etiology such as pemphigoid gestationis. [aocd.org]
However, when itching is accompanied by discrete skin lesions of uncertain etiology, biopsy can be appropriate. [merckmanuals.com]
This report describes the investigation in Crawford County, Kansas, by public health agencies and entomologists to identify the etiology of the pruritic rash and to assess the extent of the outbreak. [cdc.gov]
Epidemiology
Chikungunya fever: an epidemiological review of a re-emerging infectious disease. Clin Infect Dis 2009 ; 49 : 942 – 8. 4 Centers for Disease Control and Prevention. Chikungunya virus. . 5 Pan American Health Organization. [academic.oup.com]
Epidemiological and clinical study of grain itch. JAMA 1952;150:575--9. Peter M. Beware of oak leaf gall mites; they may be coming back. K-State Research and Extension News; May 6, 2005. [cdc.gov]
The epidemiology of pruritus depends on its underlying cause or causes. However, in general, the incidence of chronic pruritus increases with age, it is more common in women, and in those of Asian background. [dermnetnz.org]
In this article the epidemiology, risk factors, clinical presentation, radiographic findings and management is discussed. The majority of patients with small joint osteoarthritis respond well to non surgical treatments. [edoc.co.za]
Histopathological and epidemiological characteristics of patients with erythema exudativum multiforme major, Stevens-Johnson syndrome and toxic epidermal necrolysis. Br J Dermatol. 1996;135(1):6–11. 39. Kemmett D, Hunter JA. [aafp.org]
Pathophysiology
Dermatitis herpetiformis: pathophysiology, clinical presentation, diagnosis and treatment. An Bras Dermatol 2014;89(6):865–77. [racgp.org.au]
The exact pathophysiology and etiology of VZV reactivation is unknown, but an age-related decline in VZV-specific cell mediated immune responses appears to be important. ( JAMA 2009;302[1]:108.) [journals.lww.com]
Back to Top Pathophysiology Peripheral Mechanisms Physical Stimuli and Neural Pathways Itch can be produced by mechanical (gentle touch, pressure, vibration, and wool), thermal and electrical stimuli such as transcutaneous or direct nerve stimulation. [clevelandclinicmeded.com]
Pathophysiology Itch can be prompted by diverse stimuli, including light touch, vibration, and wool fibers. There are a number of chemical mediators as well as different mechanisms by which the sensation of itch occurs. [merckmanuals.com]
Prevention
This vaccine does not prevent infection but prevents reactivation of the latent virus by suppression because only those who have previously been infected with VZV can get shingles. [journals.lww.com]
The best way to prevent pruritus is to take care of your skin. To protect skin: Use skin creams and lotions that moisturize your skin and prevent dryness. Use sunscreens regularly to prevent sunburns and skin damage. [webmd.com]
Preventing PUPPS Since no one is really sure what causes PUPPS exactly, there isn’t a guaranteed way to prevent it. You can however make some healthy choices that may decrease or prevent your chances of getting the condition. [mamanatural.com]
Can I prevent PUPPP? Unfortunately, there are none. If you're going to get PUPPP, you're going to get it. Try to remember, though, that it's temporary and will disappear soon after your beautiful baby is born. [whattoexpect.com]
A randomized trial comparing fluconazole with clotrimazole troches for the prevention of fungal infections in patients with advanced human immunodeficiency virus infection. Página 454 - Delaney KM, Moorman AC, et al. [books.google.es]