It classically presents as porcelain white hypopigmented and slightly depressed atrophic plaque. There is no standard treatment for PPB. [ncbi.nlm.nih.gov]

• Asymptomatic

  Pseudopelade of Brocq A chronic asymptomatic primary cicatricial alopecia most often involving the vertex. It is non-inflammatory. The classic appearance of pseudopelade is the so-called footprints in the snow. [hairtransplantfue.org]

  (redirected from pseudopelade of Brocq ) pseudopelade [ soo″do-pe´lād ] an uncommon type of alopecia characterized by the asymptomatic development of a distinctive scarlike patchy alopecia in adults. pseu·do·pe·lade ( sū'dō-pĕ-lahd' ), A scarring type [medical-dictionary.thefreedictionary.com]

  History The typical pseudopelade of Brocq patient is surprised to discover discrete asymptomatic areas of scalp hair loss (most commonly affecting the vertex and parietal scalp [2] ). [emedicine.medscape.com]

• Collapse

  Analysis of tissue biopsies of end stage lesions show that all follicular structures including sebaceous epithelium are destroyed to be replaced by collapsed and aggregated follicular adventitia. [keratin.com]

• Pruritus

  The most common symptoms were increased shedding/hair loss (100%), pruritus (35%), and scalp tenderness (46%). [jdrntruhs.org]

  First signs of LPP include alopecia and pruritus. Rarely pain, burning, and seborrheic dermatitis are observed. [intechopen.com]

  Scalp lice should always be sought in cases of hair loss accompanied by pruritus. Lice are most likely to be found around and behind the ears and on the nape of the neck. Lymphadenopathy may also be present. [what-when-how.com]

  APPROACH TO THE PATIENT  History      Clinical Findings    Onset Presence of- pruritus, irritation, pain, erythema and/or drainage from the scalp Evaluate for autoimmune disease, systemic illness, infections, neoplasms, associated inflammatory [slideshare.net]

  In DLE, the activity of the disease is primarily focused in the center of the plaque, whereas in LPP the activity predominately occurred at the periphery.[14&16] Scalp pain and pruritus were more pronounced in LPP.A positive hair pull test assisted in [article.sapub.org]

• Sweating

  […] vulgaris, Chloracne, Blackhead ) · Rosacea ( Perioral dermatitis, Rhinophyma ) Follicular cysts Epidermoid cyst · Trichilemmal cyst · Sebaceous cyst · Steatocystoma multiplex Inflammation Pseudofolliculitis barbae · Hidradenitis suppurativa · Folliculitis Sweat [wikidoc.org]

  There are many different types of congenital and inherited hair loss.43 These include congenital hypotrichosis with or without associated defects, congenital triangular alopecia, and many ectodermal dysplasias that affect the hair, teeth, nails, and sweat [what-when-how.com]

• Leukonychia

  Cicatricial alopecia Louis-Anne-Jean Brocq List of cutaneous conditions References Template:Skin-appendage-stub v t e Disorders of skin appendages ( L60-75, 700-709 ) Nail thickness: Onychogryphosis · Onychauxis color: Beau's lines · Yellow nail syndrome · Leukonychia [wikidoc.org]

  Muehrcke's nails – Muehrckes nails, Muehrckes lines, or leukonychia striata are changes in the fingernail that may be a sign of an underlying medical disorder or condition. Muehrckes lines are lines that extend all the way across the nail. [wikivisually.com]

• Yellow Nails

  […] thickness: Onychogryphosis · Onychauxis color: Beau's lines · Yellow nail syndrome · Leukonychia shape: Koilonychia · Clubbing other: Ingrown nail · Anonychia Hair Hair loss Alopecia areata ( Alopecia totalis, Alopecia universalis, Ophiasis ) Androgenic [wikidoc.org]

• Anhidrosis

  Rosacea ( Perioral dermatitis, Rhinophyma ) Follicular cysts Epidermoid cyst · Trichilemmal cyst · Sebaceous cyst · Steatocystoma multiplex Inflammation Pseudofolliculitis barbae · Hidradenitis suppurativa · Folliculitis Sweat glands eccrine ( Miliaria, Anhidrosis [wikidoc.org]

• Lymphocytic Infiltrate

  Biopsy in the elder brother showed typical changes with reduced numbers of hair follicles and sebaceous glands, a sparse lymphocytic infiltrate and an absence of widespread scarring. A third family member may have been affected. [ncbi.nlm.nih.gov]

Even with treatment, some cases to spread, albeit very slowly The goal of treatment is to stop the disease. Hair regrowth in the bald areas is not possible in most cases. Even with treatment, some hair loss can still occur, albeit very slowly. [canadianhairlossfoundation.org]

The choice of treatment prescribed varies from person to person and depends mainly on the activity, extent of the disease and patient's tolerance to the treatment. [rarediseases.info.nih.gov]

Treatment The treatment by the dermatologist aimed at trying to slow down the process. There medication may be prescribed for external use; such as cortisone ointment or internal use, such as doxycycline or Plaquenil. [goodstrict.com]

Another belief is that PPB is the end result of any inflammatory alopecia and no further treatment is needed. The mechanism is unknown as to why this occurs. [drhillhairloss.com]

The prognosis is variable and depends on the etiology and severity of hair loss. [amboss.com]

Prognosis In reference to pseudopelade as a burnt-out form of alopecia discoid lupus erythematosus (DLE) or lichen planopilaris (LLP), the prognosis depends on the underlying disease process. [emedicine.medscape.com]

Alopecia areata: Part 1: pathogenesis, diagnosis, and prognosis. Spano F, Donovan JC. Spano F, et al. Can Fam Physician. 2015 Sep;61(9):751-5. Can Fam Physician. 2015. PMID: 26371097 Free PMC article. Review. [pubmed.ncbi.nlm.nih.gov]

Prognosis - Pseudo-Pelade of Brocq Not supplied. Treatment - Pseudo-Pelade of Brocq As the cause of this diseases is still unknown, pinpointing this problem is quite hard since there are no obvious signs of inflammation of the scalp. [checkorphan.org]

The prognosis is variable and depends on the etiology and severity of hair loss. [amboss.com]

Clinical cases PSEUDOPELADE OF BROCQ Pseudopelade of Brocq is a chronic, slowly progressive, lymphocytic cicatricial alopecia whose exact etiology remains unknown. [revistasrd.ro]

Its etiology is not fully understood [ 4, 29 ]. [intechopen.com]

We have treated 17 patients having a progressive pseudopelade with acitretin or thalidomide, two treatments effectives in discoid lupus erythematosus and in lichen planus, the main etiologies of pseudopelade. [ehrs.org]

[…] different from the slow but steady disease progression seen in several other forms of scarring alopecia. [10, 11] As the condition progresses, pseudopelade of Brocq patients may become emotionally distressed with the lack of treatment options and uncertain etiology [emedicine.medscape.com]

Epidemiology Most common type of alopecia Prevalence : Increases with age Sex: ♂ > ♀ (but very common in women as well) Age at onset: puberty in males; menopause in females Ethnicity: more common in white populations Etiology Increased androgen sensitivity [amboss.com]

Epidemiology Frequency The true prevalence of pseudopelade of Brocq in the general population is unknown, but it would appear to be very uncommon. Race Pseudopelade of Brocq is more common in whites. [emedicine.medscape.com]

Objective: To evaluate the epidemiological, clinical, and histopathological characteristics of various acquired primary cicatricial alopecias. [jdrntruhs.org]

Pseudopelade of brocq clinical features Attempts to clearly explain pseudopelade of Brocq clinicopathologically have been unsuccessful, and the true epidemiology of pseudopelade of Brocq remains an unsolved mystery. [keratin.com]

Pathophysiology The following two types of pseudopelade of Brocq are recognized: Burnt-out or end-stage scarring alopecias (eg, LLP, DLE) [5] - Pathophysiology corresponds to underlying disease process Primary idiopathic pseudopelade - Pathophysiology [emedicine.medscape.com]

Burnt - out or end-stage scarring alopecias (e.g., lichen planopilaris [LPP], discoid lupus erythematosus [DLE]) Pathophysiology corresponds to underlying disease process.[ 11 ] Primary idiopathic pseudopelade where pathophysiology is unknown. [ncbi.nlm.nih.gov]

In the beginning of the disease process, certain medication, such as steroids, may be used in an effort to prevent further hair loss. [1] [3] Last updated: 9/15/2016 [rarediseases.info.nih.gov]