Symptoma

Pseudopelade of Brocq

AB - We report a case of a 16-year-old girl affected by pseudopelade of Brocq who presented with hair casts at the borders of the lesion. [moh-it.pure.elsevier.com]

Four patients are presented with pseudopelade of Brocq whose symptoms also illustrate the spectrum of symptoms of lichen planus. [ncbi.nlm.nih.gov]

  • Collapse

    Analysis of tissue biopsies of end stage lesions show that all follicular structures including sebaceous epithelium are destroyed to be replaced by collapsed and aggregated follicular adventitia. [keratin.com]

  • Nail Abnormality

    Sean Linford, nail Abnormalities, Clues to Systemic Disease. James, William, Berger, Timothy, Elston, Dirk, andrews Diseases of the Skin, Clinical Dermatology. Muehrcke Lines of the Fingernails at eMedicine Muehrckes Lines of the Fingernails on WebMD [wikivisually.com]

  • Pruritus

    The most common symptoms were increased shedding/hair loss (100%), pruritus (35%), and scalp tenderness (46%). [jdrntruhs.org]

    First signs of LPP include alopecia and pruritus. Rarely pain, burning, and seborrheic dermatitis are observed. [intechopen.com]

    Scalp lice should always be sought in cases of hair loss accompanied by pruritus. Lice are most likely to be found around and behind the ears and on the nape of the neck. Lymphadenopathy may also be present. [what-when-how.com]

    APPROACH TO THE PATIENT  History      Clinical Findings    Onset Presence of- pruritus, irritation, pain, erythema and/or drainage from the scalp Evaluate for autoimmune disease, systemic illness, infections, neoplasms, associated inflammatory [slideshare.net]

    In DLE, the activity of the disease is primarily focused in the center of the plaque, whereas in LPP the activity predominately occurred at the periphery.[14&16] Scalp pain and pruritus were more pronounced in LPP.A positive hair pull test assisted in [article.sapub.org]

  • Leukonychia

    Cicatricial alopecia Louis-Anne-Jean Brocq List of cutaneous conditions References Template:Skin-appendage-stub v t e Disorders of skin appendages ( L60-75, 700-709 ) Nail thickness: Onychogryphosis · Onychauxis color: Beau's lines · Yellow nail syndrome · Leukonychia [wikidoc.org]

    Muehrcke's nails – Muehrckes nails, Muehrckes lines, or leukonychia striata are changes in the fingernail that may be a sign of an underlying medical disorder or condition. Muehrckes lines are lines that extend all the way across the nail. [wikivisually.com]

  • Anhidrosis

    Rosacea ( Perioral dermatitis, Rhinophyma ) Follicular cysts Epidermoid cyst · Trichilemmal cyst · Sebaceous cyst · Steatocystoma multiplex Inflammation Pseudofolliculitis barbae · Hidradenitis suppurativa · Folliculitis Sweat glands eccrine ( Miliaria, Anhidrosis [wikidoc.org]

  • Yellow Nails

    nail syndrome · Leukonychia shape: Koilonychia · Clubbing other: Ingrown nail · Anonychia Hair Hair loss Alopecia areata ( Alopecia totalis, Alopecia universalis, Ophiasis ) Androgenic alopecia · Hypotrichosis · Telogen effluvium · Traction alopecia [wikidoc.org]

  • Acneiform Eruption

    eruption ( Acne vulgaris, Chloracne, Blackhead ) · Rosacea ( Perioral dermatitis, Rhinophyma ) Follicular cysts Epidermoid cyst · Trichilemmal cyst · Sebaceous cyst · Steatocystoma multiplex Inflammation Pseudofolliculitis barbae · Hidradenitis suppurativa [wikidoc.org]

  • Borrelia Burgdorferi

    Other factors that may be involved include infections with Borrelia burgdorferi, the bacterium that causes Lyme disease and issues with the cells involved in hair growth ( stem cell failure). [1] [2] [3] There is no standard treatment for PBB. [rarediseases.info.nih.gov]

Even with treatment, some cases to spread, albeit very slowly The goal of treatment is to stop the disease. Hair regrowth in the bald areas is not possible in most cases. Even with treatment, some hair loss can still occur, albeit very slowly. [canadianhairlossfoundation.org]

The choice of treatment prescribed varies from person to person and depends mainly on the activity, extent of the disease and patient's tolerance to the treatment. [rarediseases.info.nih.gov]

Treatment The treatment by the dermatologist aimed at trying to slow down the process. There medication may be prescribed for external use; such as cortisone ointment or internal use, such as doxycycline or Plaquenil. [goodstrict.com]

Early detection and treatment can prevent progression of hair loss and possibly reverse alopecia if caught early. [socahcenter.com]

The prognosis is variable and depends on the etiology and severity of hair loss. [amboss.com]

Prognosis In reference to pseudopelade as a burnt-out form of alopecia discoid lupus erythematosus (DLE) or lichen planopilaris (LLP), the prognosis depends on the underlying disease process. [emedicine.medscape.com]

Prognosis - Pseudo-Pelade of Brocq Not supplied. Treatment - Pseudo-Pelade of Brocq As the cause of this diseases is still unknown, pinpointing this problem is quite hard since there are no obvious signs of inflammation of the scalp. [checkorphan.org]

Procedures Scalp biopsy is required for determining both diagnosis and prognosis. · Ideally, the biopsy specimen is at least 4 mm in diameter and is sectioned transversely (horizontal to scalp surface). [ourdermatology.blogspot.com]

The prognosis is variable and depends on the etiology and severity of hair loss. [amboss.com]

Clinical cases PSEUDOPELADE OF BROCQ Pseudopelade of Brocq is a chronic, slowly progressive, lymphocytic cicatricial alopecia whose exact etiology remains unknown. [revistasrd.ro]

We have treated 17 patients having a progressive pseudopelade with acitretin or thalidomide, two treatments effectives in discoid lupus erythematosus and in lichen planus, the main etiologies of pseudopelade. [ehrs.org]

[…] different from the slow but steady disease progression seen in several other forms of scarring alopecia. [10, 11] As the condition progresses, pseudopelade of Brocq patients may become emotionally distressed with the lack of treatment options and uncertain etiology [emedicine.medscape.com]

Its etiology is not fully understood [ 4, 29 ]. [intechopen.com]

Epidemiology Most common type of alopecia Prevalence : Increases with age Sex: (but very common in women as well) Age at onset: puberty in males; menopause in females Ethnicity: more common in white populations Etiology Increased androgen sensitivity [amboss.com]

Pseudopelade of brocq clinical features Attempts to clearly explain pseudopelade of Brocq clinicopathologically have been unsuccessful, and the true epidemiology of pseudopelade of Brocq remains an unsolved mystery. [keratin.com]

Epidemiology Frequency The true prevalence of pseudopelade of Brocq in the general population is unknown, but it would appear to be very uncommon. Race Pseudopelade of Brocq is more common in whites. [emedicine.medscape.com]

Objective: To evaluate the epidemiological, clinical, and histopathological characteristics of various acquired primary cicatricial alopecias. [jdrntruhs.org]

lichen planopilaris [LPP], discoid lupus erythematosus [DLE]) Pathophysiology corresponds to underlying disease process.[ 11 ] Primary idiopathic pseudopelade where pathophysiology is unknown. [ncbi.nlm.nih.gov]

Pathophysiology The following two types of pseudopelade of Brocq are recognized: Burnt-out or end-stage scarring alopecias (eg, LLP, DLE) [5] - Pathophysiology corresponds to underlying disease process Primary idiopathic pseudopelade - Pathophysiology [emedicine.medscape.com]

In the beginning of the disease process, certain medication, such as steroids, may be used in an effort to prevent further hair loss. [1] [3] Last updated: 9/15/2016 [rarediseases.info.nih.gov]