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Pulmonary Arteriosclerosis
Arteriosclerosis Pulmonary

Presentation

Presented before The American College of Physicians at the San Francisco Meeting, April 6, 1932. [acpjournals.org]

When severe, as in longstanding mitral stenosis, obvious lesions are present, and mild changes are present in the pulmonary arterial system. [histopathology-india.net]

We report a case of a young boy with cblC defect, who did not undergo newborn screening, presenting at the age of 2 years with isolated pulmonary hypertension as the leading symptom. [pediatrics.aappublications.org]

A 56-year old patient presented with acute onset vision loss. [eyewiki.aao.org]

[…] with exertional chest pain, shortness of breath, and fatigue distinguishing factors positive stress testing coronary vessel occlusion and normal pulmonary pressures upon catheterization Liver disease can present with lower extremity swelling and RUQ [medbullets.com]

Respiratoric

  • Pulmonary Disorder

    A decade or more ago, pulmonary hypertension was divided into primary (essential) pulmonary hypertension, which by definition was idiopathic, and hypertension that was secondary to, commonly, other cardiac or pulmonary disorders. [caymanchem.com]

Workup

What is the proper workup of a patient with hypertension? Cleve Clin J Med 75: 663-72. ↑ 4.0 4.1 Garner, A. & Ashton, N. 1979. Pathogenesis of hypertensive retinopathy: a review. [eyewiki.aao.org]

[…] anorexia (from hepatic congestion) Physical examination loud P2 on auscultation right-sided heave from right ventricular hypertrophy if subsequent right heart failure elevated JVP hepatomegaly S3 heart sound Imaging Echocardiogram usually first step in the workup [medbullets.com]

Standard laboratory workup--including pulmonary function testing and screening for systemic diseases and those related to human immunodeficiency virus (HIV)--was normal. [revespcardiol.org]

As in other studies, the PPH was diagnosed by a thorough workup, including clinical history, physical examination, laboratory tests, chest radiography, ECG, pulmonary function tests, echocardiography, radionuclide perfusion lung scan and cardiac catheterization [kjim.org]

Treatment

Treatment is now actively pro moted by public health agencies, including the World Health Organization. This is an other case of treatment preceding full understanding of the nature of the disease. [books.google.com]

More research on the causes, prevention, and treatment of DVT. [vascularcures.org]

Medical Treatment for Pulmonary Edema When a patient is in respiratory distress, the initial treatment will occur at the same time or even before the diagnosis is made. [emedicinehealth.com]

Depending upon the timing of this treatment in relation to the alleged onset date of disability, we may need to defer evaluation of the impairment for a period of up to 3 months from the date treatment began to permit consideration of treatment effects [ssa.gov]

Prognosis

We analyzed determinants associated with the survival and prognosis of patients with PPH. MATERIALS AND METHODS 1. [kjim.org]

[…] hypertension (IPAH) By definition, the cause is unknown Hereditary pulmonary arterial hypertension (HPAH) Mutation in the BMPR-2 gene acts normally to inhibit smooth muscle growth Mnemonic: B locker of M uscle PR oliferation More common in women (9:1) Poor prognosis [medbullets.com]

Stenting of the LMCA can be carried out with good angiographic results at experienced centers, although too few case histories are available to ascertain its impact on the prognosis of these patients. Correspondence: Dr. P.M. Montes Orbe. [revespcardiol.org]

This is the hallmark of malignant hypertension, which carries a poor prognosis for the patient’s health if left untreated. [eyewiki.aao.org]

Collectively, our results indicate that both airway and pulmonary vessel remodeling impact negatively upon the prognosis of COPD. [dovepress.com]

Etiology

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]

Etiologies Etiology Key Points Idiopathic pulmonary arterial hypertension (IPAH) By definition, the cause is unknown Hereditary pulmonary arterial hypertension (HPAH) Mutation in the BMPR-2 gene acts normally to inhibit smooth muscle growth Mnemonic: [medbullets.com]

This book is organized into three sections encompassing 15 chapters that also cover the etiology of acute cardiopulmonary diseases and chronic pulmonary hypertension. [books.google.com]

[…] fibrosis Types laminar intimal fibrosis intimal fibroplasia Patterns concentric intimal fibrosis allograft chronic rejection asymetrical intimal fibrosis atherosclerosis and arteriosclerosis Localization arterial intimal fibrosis veinous intimal fibrosis Etiology [humpath.com]

[…] chest wall), anorexiants (e.g., fenfluramine, possibly also phentermine). plexogenic pulmonary arteriopathy Pulmonary disease A vasculopathy seen in pulmonary HTN, characterized by medial hypertrophy of muscular pulmonary arteries, fibrinoid necrosis Etiology [medical-dictionary.thefreedictionary.com]

Epidemiology

Introduction Clinical definition mean pulmonary artery pressure ≥ 20 mmHg normal = 8-20 mmHg gold standard for measurement is right heart catheterization Epidemiology incidence varies by etiology; affects all ages, races, and genders can be very rare [medbullets.com]

Additional epidemiologic initiatives also are needed to ascertain the prevalence and incidence of the various disease entities. [cdc.gov]

Pulmonary hypertension in COPD: epidemiology, significance, and management: pulmonary vascular disease: the global perspective. Chest. 2010;137(6 Suppl):39S–51S. 4. Hurdman J, Condliffe R, Elliot CA, et al. [dovepress.com]

Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International [journals.plos.org]

Pathophysiology

While this may be an extreme example, there are pathophysiological situations in which a reduction in arterial compliance leads to an elevated systolic pressure and reduced diastolic pressure, yielding a calculated mean arterial pressure that is close [physiologyweb.com]

This broadens the scope of the relevant pathophysiology tremendously. [caymanchem.com]

Pathophysiology Retinal hemorrhages (Figure 1-3) develop when necrotic vessels bleed into either the nerve fiber layer (flame shaped hemorrhage) or the inner retina (dot blot hemorrhage). [eyewiki.aao.org]

The pathophysiology of failure in acute right ventricular hypertension: hemodynamic and biochemical correlation. Circulation 1981;63:87-95. Medline 4. Vizza CD, Lynch JP, Ochoa LL, Richardson G, Trulock EP. [revespcardiol.org]

[…] diagnosis of pulmonary hypertension requires direct pulmonary arterial pressure measurements that involve right heart catheterization. 5 The analysis of chest computed tomography (CT) scans in COPD has contributed greatly to our understanding of the pathophysiology [dovepress.com]

Prevention

Prevention Prevention of PE is a lot easier than diagnosis or treatment. Therefore, when hospitalized, it is important to ask your health care providers what measures are being taken to prevent PE. [vascularcures.org]

Prevention The same healthy lifestyle changes recommended to treat atherosclerosis also help prevent it. [mayoclinic.org]

Prevention Preventing the development of atherosclerosis is one of the best ways to treat the condition. Steps to limit the risk of plaque buildup include: Diet: Try to avoid saturated fats, they increase levels of bad cholesterol. [medicalnewstoday.com]

Prevention Try to follow these tips to prevent atherosclerosis: Quit smoking. Smoking accelerates the development of atherosclerosis, which often leads to coronary heart disease. [healthywomen.org]

Mensah, MD Division for Heart Disease and Stroke Prevention National Center for Chronic Disease Prevention and Health Promotion This material in this report originated in the National Center for Chronic Disease Prevention and Health Promotion, Janet L [cdc.gov]

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