Symptoma

Pulmonary Blastoma

Classic Pulmonary Blastoma

Pleural effusion may be present but is not the predominant abnormality. Our cases are unusual as recurrent pleural effusions in the absence of a significant lung mass were the presenting findings. [ncbi.nlm.nih.gov]

  • Malignant Pleural Effusion

    Patients 5 and 6 were initially considered inoperable due to malignant pleural effusion and left atrial involvement, respectively. Neoadjuvant chemotherapy successfully downstaged the tumors before surgical excision (Fig 1). [annalsthoracicsurgery.org]

    There now is mounting evidence that it may be effective; Kummet and Doll initially described its use as a second‐line agent in the treatment of a patient whose metastatic disease presented as malignant pleural effusions 18 months after initial resection [onlinelibrary.wiley.com]

  • Orthopnea

    Probl Cardiol. 1999; 24: 57–116 Abstract Full Text PDF PubMed Google ScholarSee all References REPORT OF A CASE A 45-year-old man with a history of tobacco use presented to our emergency department because of a 3-week history of increasing dyspnea, orthopnea [mayoclinicproceedings.org]

  • Loss of Initiative

    The patient reported no symptoms of shortness of breath, hemoptysis, chest pain, fever, chills, or weight loss. Amoxicillin initially was prescribed without symptomatic response. [onlinelibrary.wiley.com]

  • Psychiatric Symptoms

    In all patients with epithelial or mesenchymal tumors that exhibit neuro psychiatric symptoms, NICTH should be considered [ 7 ]. Our patient reported weakness, tiredness, and excessive sweating. [ncbi.nlm.nih.gov]

In addition, cytological diagnosis of Blastomyces dermatitidis in sputum and bronchial washings of patients suspected of having a pulmonary cancer or infection reduced the time of diagnostic workup and the incidence of major surgery. ( JAMA 1981;245:836 [jamanetwork.com]

He underwent workup for distant metastasis, the findings of which were unremarkable. Therefore, left lower lobectomy was performed with lymph node dissection. [kjim.org]

  • Anterior Mediastinal Mass

    Chest radiograph and computed tomography of thorax revealed an anterior mediastinal mass that was subjected to ultrasound-guided fine-needle aspiration cytology. [jcytol.org]

    FIGURE 1 Computed tomography of the chest shows a 13 cm anterior mediastinal mass. FIGURE 2 Computed tomography of the chest at the time of surgical biopsy shows rapid progression in 19 days. [jto.org]

  • Left Pleural Effusion

    However, she finally developed progressive disease with enlarged left lung lesion and increased left pleural effusion, achieving a progression-free survival of 3 months. [dovepress.com]

  • Normocytic Anemia

    The laboratory examination revealed only a mild normocytic anemia. The serum carcinoembryonic antigen (CEA) was 2.3 ng/mL. Bronchoscopy was performed and was normal, without evidence of an intrabronchial lesion. [onlinelibrary.wiley.com]

The world literature was reviewed with regard to the use of adjuvant chemotherapy in the treatment of pulmonary blastoma. [ncbi.nlm.nih.gov]

We present a case of a classic biphasic pulmonary blastoma, a rare lung cancer occurring at an earlier age and portending to poorer prognosis than other more common lung cancers. [ncbi.nlm.nih.gov]

A GI etiology was initially treated unsuccessfully with antireflux medications. A chest radiograph showed a 4.6-cm mass in the right upper lobe of the lung, and computed tomography showed right apical bullous formation with no lymphadenopathy. [ncbi.nlm.nih.gov]

Etiology Little is known about the pathogenesis and histogenesis of PB. Molecular studies indicate that mesenchymal and epithelial components are derived from a single precursor cell. [orpha.net]

[…] life (90% are between 0 - 2 years old) Type I may be found in very young children (birth to 2 years of age) Types II and III tend to be found after 2 years of age (Pediatr Dev Pathol 2015;18:504) Sites PPB may arise in the lung, mediastinum and pleura Etiology [pathologyoutlines.com]

In spite of diligent investigations by many competent investigators, we still do not know the ecological niche inhabited by the etiologic agent. We have many tantalizing clues but no definite answers. [books.google.ro]

The etiology and predisposing factors are not still fully understood. But, in the literature, there is strong evidence showing the correlation between cigarette smoking and pulmonary blastoma [7]. [raftpubs.com]

Given the small number of cases and recent re-classification, interpreting the published epidemiology and clinical features of this disease is difficult. [ncbi.nlm.nih.gov]

Pulmonary embryoma Definitions PB monophasic type (well-differentiated fetal adenocarcinoma) Glandular component recapitulates embryonic development of lung PB biphasic type Composed of epithelial glandular component and sarcomatous elements CLINICAL ISSUES Epidemiology [basicmedicalkey.com]

Essential features Peripheral solitary large mass, well circumscribed, unencapsulated Well differentiated glandular component and blastematous stroma ICD coding ICD-O: 8972/3 - pulmonary blastoma Epidemiology Most common in fifth decade M:F 1:1 Diagnosis [pathologyoutlines.com]

The possible pathophysiological causes of hypoglycemia include increases in secretion of IGF, invasion of the liver by a tumor, disruption of counter regulatory mechanisms as a result of adrenal blockage, increase on consumption of glucose by the tumor [ncbi.nlm.nih.gov]

Macklin published further insights into the pathophysiology of spontaneous Macklin's Syndrome occurring from a severe asthmatic attack. [findzebra.com]

Subsequent administration of high dose melphalan, etoposide, and carboplatin, followed by autologous blood stem cell transplantation resulted in a 3-month disease-free interval but did not prevent eventual local recurrence, leading to death within a few [ncbi.nlm.nih.gov]

Every attempt should be made to remove completely all cystic remnants to prevent reccurence of PPB. In case of reccurence, Type I recurrences frequently progress to more serious Type II or III disease. [telemedicina.med.muni.cz]

Elective surgery is safe, prevents the development of symptoms and reduces complications13,14. PPB usually produces respiratory symptoms, but it may be an incidental diagnosis15. [scielo.conicyt.cl]

Final Research Plan: Screening for Lung Cancer - US Preventive Services Task Force Final Research Plan: Screening for Lung Cancer - US Preventive Services Task Force … Cancer August 16, 2018 – The U.S. … Preventive Services Task Force posted today a final [search.uspreventiveservicestaskforce.org]

How can Pulmonary Blastoma be Prevented? Currently, there is no known prevention method for Pulmonary Blastoma. [dovemed.com]