Presentation
The case reported is presented as a typical example of pulmonary pneumatocele following pneumonia in an infant. No attempt is made in this report to discuss the etiologic or the physiologic aspects of cystic disease of the lung. [jamanetwork.com]
Operative checklists are included in procedural chapters, and procedures are presented as bulleted to-do lists wherever possible. [books.google.com]
Although bullous lung disease is sometimes asymptomatic and found only incidentally on imaging, it commonly presents with symptoms. [clinicaladvisor.com]
Entire Body System
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Lymphadenopathy
There was no lymphadenopathy. There were surgical clips on the right hemidiaphragm with minimal postoperative pleural thickening along the right costophrenic recess (prior surgery from bullet wound). [journal.copdfoundation.org]
tumor; lymphadenopathy; mediastinal mass) Emphysema Pneumothorax Discussion Bullous emphysema refers to the presence of emphysema associated with large bulla. [vcuthoracicimaging.com]
Hilar lymphadenopathy is visible in 50% and usually there is a history of malignancy. [radiologyassistant.nl]
Significant hilar or mediastinal lymphadenopathy is not seen in uncomplicated bullous lung disease, so its presence may raise suspicion for cavitating infection, malignancy, or possibly fibrocavitary sarcoidosis. [clinicaladvisor.com]
Immune System
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Mediastinal Lymphadenopathy
Significant hilar or mediastinal lymphadenopathy is not seen in uncomplicated bullous lung disease, so its presence may raise suspicion for cavitating infection, malignancy, or possibly fibrocavitary sarcoidosis. [clinicaladvisor.com]
Additional findings Pleural effusion is seen in: Pulmonary edema Lymphangitic spread of carcinoma - often unilateral Tuberculosis Lymphangiomyomatosis (LAM) Asbestosis Hilar and mediastinal lymphadenopathy In sarcoidosis the common pattern is right paratracheal [radiologyassistant.nl]
Respiratoric
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Barrel Chest
This may also add to the appearance of a barrel chest. Bulla (Bullae). As more lung tissue is destroyed over time, this creates one large air space rather than many smaller ones. [healthcentral.com]
diaphragm flattening and barrel chest) and increasing the work of breathing. Although bullous lung disease is sometimes asymptomatic and found only incidentally on imaging, it commonly presents with symptoms. [clinicaladvisor.com]
Chest x-ray : not sensitive, especially during early stages Barrel chest Horizontal ribs and widened intercostal spaces Increased anteroposterior diameter The diaphragm is pushed down and flattened. [amboss.com]
Signs of emphysema include: tachypnea absence of cyanosis pursed-lip breathing, tripod position chest hyperinflation "barrel chest" reduced breath sounds hyper-resonant to percussion cor pulmonale (late) Emphysema is one of a heterogeneous group of pathological [radiopaedia.org]
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Sputum Production
Rarely, fever and malaise /- increased sputum production, may signal an infected bulla. Chest imaging reveals large, air-filled spaces within the lung parenchyma that are 1 cm in size with thin or poorly defined walls. [clinicaladvisor.com]
In the dental setting, it is vital for the clinician to be able to identify a patient with the cardinal signs of COPD, including, dyspnea on exertion, chronic cough and sputum production. Sputum production is often minimal when cough is present. [pulsus.com]
Increase in cough with sputum production usually indicates infection in a bulla [6]. Most of the patients of bullous emphysema are cigarette smokers. [lungindia.com]
Patients typically report dyspnea without significant sputum production. [radiopaedia.org]
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Exertional Cough
Typically, the symptoms are those of COPD: Shortness of breath or chest tightness, particularly with exertion Cough Sputum production Occasionally, a sense of abdominal fullness or bloating, usually associated with severe obstruction and prominent air-trapping [clinicaladvisor.com]
Gastrointestinal
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Abdominal Fullness
Typically, the symptoms are those of COPD: Shortness of breath or chest tightness, particularly with exertion Cough Sputum production Occasionally, a sense of abdominal fullness or bloating, usually associated with severe obstruction and prominent air-trapping [clinicaladvisor.com]
Workup
The patient had a workup that included an open biopsy, which was diagnosed as high-grade chondroblastic osteosarcoma (Figure 1). The patient subsequently underwent en bloc resection of the distal femur followed by amputation above the knee. [archivesofpathology.org]
The laboratory workup of a patient with bullous emphysema is not standardized, but it may include the following considerations: Particularly in those with disease onset at a young age ( HIV testing is indicated in patients with potential risk factors, [clinicaladvisor.com]
The laboratory workup of a patient with bullous emphysema is not standardized, but it may include the following considerations: Particularly in those with disease onset at a young age ( 45), a strong family history of emphysema, or emphysema out of proportion [pulmonologyadvisor.com]
X-Ray
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Pulmonary Pneumatocele
The case reported is presented as a typical example of pulmonary pneumatocele following pneumonia in an infant. No attempt is made in this report to discuss the etiologic or the physiologic aspects of cystic disease of the lung. [jamanetwork.com]
Treatment
Multidisciplinary contributions on medical treatment, radiation oncology, and surgery and anesthesia are included. Highlights include new material on minimally invasive procedures and thoroughly updated diagnostic and treatment information. [books.google.com]
Disease progression, like all bullous emphysema, is variable and definite treatment usually requires surgical bullectomy. [pulmonologyadvisor.com]
The mean charge used for every treatment was 8 (range 4–21). [academic.oup.com]
Prognosis
Prevention, and Complications Prognosis resolves typically in 4-6 weeks or within 2 weeks postpartum no risk of fetal or maternal morbidity Please rate topic. [step2.medbullets.com]
[…] location the size of bullae ranges from 1 to 20 cm in diameter, but most measure 2-8 cm 2 usually asymmetric, with one lung involved to a greater extent than the other the presence of concomitant foci of paraseptal and centrilobular emphysema Treatment and prognosis [radiopaedia.org]
In the final stage of emphysema, when bullae are more likely to appear, the prognosis is often not good. [coughingupblood.net]
Etiology
However, the etiology and pathogenesis of bullae and their association with emphysema are not yet elucidated. [journals.lww.com]
No attempt is made in this report to discuss the etiologic or the physiologic aspects of cystic disease of the lung. [jamanetwork.com]
The etiology of the obstruction in bullous emphysema is frequently obscure. [pubs.rsna.org]
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
Vanishing lung syndrome or idiopathic giant emphysematous bulla, is a rare syndrome in which bullae take up 30% of the affected hemithorax with no identifiable underlying etiology. [clinicaladvisor.com]
Epidemiology
Heritability studies of COPD suggest that there are likely other genetic risk factors, and a number of genetic epidemiology studies suggest new potential candidates. [clinicaladvisor.com]
[…] increasing world wide and most commonly smoked by young and adolescents Several case reports have implicated marijuana smoking as an etiologic factor in Pneumothorax/pneumomediastinum and bullous lung disease, although evidence of a possible causal link from epidemiologic [erj.ersjournals.com]
Introduction Pruritic urticarial papules and plaques of pregnancy (PUPPP) or polymorphic eruption of pregnancy (PEP) A self-limited pruritic inflammatory disorder of the skin occurring in the last trimester of pregnancy or immediately postpartum Epidemiology [step2.medbullets.com]
Pruritic urticarial papules and plaques of pregnancy: epidemiological, clinical, and histopathological study of 18 cases from Lebanon. Int. J. Dermatol. 2012 Sep;51(9):1047-53. [PubMed: 22909357] 11. Holmes RC, Jurecka W, Black MM. [ncbi.nlm.nih.gov]
Pathophysiology
Pathology Microscopic tumor embolism Thought to occur from two distinct pathophysiological processes. [radiopaedia.org]
The pathophysiology responsible for the natural elimination of giant bullae is not known with certainty. We report a patient who experienced spontaneous sub-total regression of his giant bulla following an infection. [austinpublishinggroup.com]
Pathophysiology The pathophysiology of bullous emphysema is intimately related to the chronic inflammation of the distal airspaces mostly secondary to insult, i.e., cigarette smoke, which results in a breakdown of the alveolar walls which subsequently [ncbi.nlm.nih.gov]
Prevention
[…] best way to prevent emphysema or stop it from getting worse. [medicalnewstoday.com]
Treatments include inhalers, oxygen, medications and sometimes surgery to relieve symptoms and prevent complications. [icdlist.com]
Preventing COPD COPD is largely a preventable condition. You can significantly reduce your chances of developing it if you avoid smoking. [nhs.uk]
Generally, this is no different than for typical emphysema, and includes: Quitting smoking (slows progression of the disease) Controlling COPD triggers (prevents flare-ups) COPD Medicines (prevents and controls flare-ups) Pulmonary rehabilitation. [healthcentral.com]
Newer research, however, suggests there is negative intra-bullous pressure, similar to pleural pressure, and is thus preferentially ventilated during inspiration with loss of elastic recoil preventing air from being expelled. [vcuthoracicimaging.com]