This case report discusses the benign versus malignant nature of this rare tumor Purpose (a): Purpose of this study was to present a case study describing the presentation of a very rare lung tumor, a sugar cell clear cell tumor. [digitalcommons.hsc.unt.edu]

We report a case of sugar tumor in a 64-yr-old man presenting as a round pulmonary nodule. [ncbi.nlm.nih.gov]

• Pathologist

  When your lung was biopsied, the samples taken were studied under the microscope by a specialized doctor with many years of training called a pathologist. The pathologist sends your doctor a report that gives a diagnosis for each sample taken. [cancer.org]

  A must-have reference for cytotechnology students, cytotechnologists, pathologists, pathology residents, cytopathologists, as well as pulmonologists. [books.google.com]

  A pathologist examines the biopsy under a microscope. After putting together clinical findings, special studies on tissues (if needed) and with microscope findings, the pathologist arrives at a definitive diagnosis. [dovemed.com]

  Pediatric renal tumors: practical updates for the pathologist. Pediatr Dev Pathol, 8 (2005), pp. 320-338 [2] P. Argani, E. Perlman, N. Breslow, N. Browning, D. Green, G. d’Angio, et al. [archbronconeumol.org]

  Miller, M.D., Director of Immunohistochemistry Clear cell carcinoma is a common specimen seen by many surgical pathologists. [propath.org]

• Anemia

  These symptoms are non-specific and common to other renal cancers.3 The most predominant paraneoplastic symptoms include anemia and Stauffer syndrome, both of which were seen in our patient. [archbronconeumol.org]

  […] with Ring Sideroblasts (RARS) Refractory Anemia with Excess Blasts (RAEB) 5q- Syndrome Myelodysplastic Syndrome, Unclassifiable (MDS-U) Myelodysplastic Syndromes with Marrow Fibrosis Myelodysplastic Syndromes, Hypocellular Myeloid and Lymphoid Neoplasms [surgpathcriteria.stanford.edu]

  Case Report In September 2000, a very active, athletic 58 year-old male in otherwise excellent health began to have progressive weight loss of 18 pounds, night sweats, anemia, fatigue, indigestion and back pain over a four month period. [austinpublishinggroup.com]

  For example, if you search for anemia the headword anaemia is displayed: If you look up a word which isn’t in the dictionary, the software attempts to find the nearest matching word. [focloir.ie]

• Goiter

  There are no characteristic radiographic differences among neoplasms, and, as in our patient, findings on ultrasound or CT scan may suggest a benign process such as multinodular goiter .5,6 Further contributing to the diagnostic difficulty, identification [path.upmc.edu]

• Pneumonia

  / diffuse parenchymal diseases Acute interstitial pneumonia (diffuse alveolar damage, DAD) Acute fibrinous and organizng pneumonia Alveolar microlithiasis Alveolar proteinosis Cryptogenic organizing pneumonia (BOOP) Desquamative interstitial pneumonia [surgpathcriteria.stanford.edu]

  Endobronchial obstruction from any of the primary or metastatic tumors may present with symptoms of pneumonia, including fever, sweats, and/or pleurisy. [pulmonologyadvisor.com]

  The most common symptoms of lung cancer include: Chest pain that doesn’t go away Shortness of breath and wheezing Recurring lung infections like pneumonia or bronchitis Bloody or rust colored sputum (coughed up mucus) Hoarseness of the throat Swelling [beaumont.org]

  Symptoms of lung cancer are unspecific and dependent on anatomical site and include persistent coughing, hemoptysis, repeated pneumonia and signs of respiratory distress. [proteinatlas.org]

  We report the case of a patient who underwent nephrectomy for stage iii renal cell carcinoma and who presented 20 months later with respiratory symptoms consistent with pneumonia, influenza, or (less likely) congestive heart failure or a cardiac event [current-oncology.com]

• Nausea

  […] cell sarcoma of the kidney: urological, general and those caused by paraneoplastic syndromes.2 Important general manifestations include asthenia, anorexia, weight loss (all seen in our patient), low-grade fever, and gastrointestinal symptoms such as nausea [archbronconeumol.org]

  The side effects include vomiting, nausea, and hair loss Radiation therapy: Radiation therapy involves using x-rays to kill cancerous cells. High-powered radiation beams are directed to particular body regions to target cancer. [dovemed.com]

  On current presentation, the patient also complained of fatigue and decreased appetite, and denied fevers, chills, nausea, vomiting, diarrhea, and constipation. [current-oncology.com]

  […] aim to inhibit the growth of new blood vessels in the tumors, hence slowing growth and in some cases reducing the size of the tumors.[99] Side effects unfortunately are quite common with these treatments and include:[100] Gastrointestinal effects – nausea [en.wikipedia.org]

• Abdominal Pain

  They usually originate from the epiphysis of long bones, but in rare cases, they may arise from anterior arc of the ribs.[7] The symptoms may include muscular aches and pains in arms or legs and abdominal pain. [en.wikipedia.org]

  Diagnosis Pediatric RCC often presents with generalized symptoms of malaise and abdominal pain. When present, localized signs and symptoms include gross hematuria, flank pain, and a palpable abdominal mass. [dovepress.com]

• Constipation

  […] the kidney: urological, general and those caused by paraneoplastic syndromes.2 Important general manifestations include asthenia, anorexia, weight loss (all seen in our patient), low-grade fever, and gastrointestinal symptoms such as nausea, vomiting, constipation [archbronconeumol.org]

  On current presentation, the patient also complained of fatigue and decreased appetite, and denied fevers, chills, nausea, vomiting, diarrhea, and constipation. [current-oncology.com]

• Abdominal Mass

  Abdominal examination revealed a large mass in the lower abdomen. The left leg was markedly swollen, with edema extending from the groin to the foot. [thefreelibrary.com]

  This classic triad[9] is 1: haematuria, which is when there is blood present in the urine, 2: flank pain, which is pain on the side of the body between the hip and ribs, and 3: an abdominal mass, similar to bloating but larger. [en.wikipedia.org]

  Diagnosis Pediatric RCC often presents with generalized symptoms of malaise and abdominal pain. When present, localized signs and symptoms include gross hematuria, flank pain, and a palpable abdominal mass. [dovepress.com]

• Hypertension

  Patients are in prolonged respiratory distress with normal chest x-ray, and with or without signs of pulmonary hypertension. Choriocarcinoma, hepatoma, breast and stomach tumors account for most of the primaries with such presentation. [meddean.luc.edu]

  […] necrotic than lung primaries May appear as multiple discrete nodules in periphery of lung or as lymphangitic carcinomatosis (peribronchial and perivascular patterns via lymphatics) Rarely appear as intralymphatic microscopic foci that cause pulmonary hypertension [pathologyoutlines.com]

  He had a history of systemic hypertension for more than 20 years, and was a current smoker with 20 pack-year history of smoking cigarettes. Physical examinations and laboratory studies showed no abnormalities. [journals.lww.com]

• Heart Disease

  Treatment may not be as effective for patients with bone or liver metastases from lung cancer, excessive weight loss, ongoing cigarette use, or pre-existing medical conditions, such as heart disease or emphysema. [cancer.net]

  Heart. Major blood vessels that lead to or from the heart. Nerve that controls the larynx (voice box). [mdanderson.org]

Respiratory cytopathology is indispensable in the workup of patients suspected of having lung cancer requiring cytologic evaluation and is used increasingly in immunocompromised patients for the identification of infectious diseases. [books.google.com]

So, although all imaging modalities are helpful in the workup, biopsy is the only way to confirm the diagnosis The evolution of the case report we are presenting was rapidly lethal but some studies have reported the effectiveness of radiotherapy in the [ispub.com]

Staging workup begins with computed tomography of the lungs, as it is the most frequent site of metastasis. [dovepress.com]

• Colitis

  Ischemic Colitis Incidental Chronic Colitis Lymphocytic Colitis Pseudomembranous Colitis Ulcerative Colitis Ulcerative Jejunoileitis Back to Top Gastrointestinal Tract (Neoplasms and Tumors) See sections below for Upper GI, Appendiceal tumors, Colorectal [surgpathcriteria.stanford.edu]

In this case, your doctor may recommend nonsurgical treatment. Nonsurgical Treatment Nonsurgical treatment may include: Radiation. [orthoinfo.aaos.org]

In these situations, the doctor will recommend other treatment options. Recurrent NSCLC Recurrent cancer is cancer that has come back after treatment. [cancer.net]

Other lung cancer treatments Doctors sometimes suggest other treatments for people with lung cancer. [beaumont.org]

[…] candidates for a second-line treatment approach. [clinicaltrials.gov]

[…] than high grade serous carcinoma However, advanced stage clear cell carcinoma has a worse prognosis (Am J Surg Pathol 2011;35:36) Presence of GPC3 is associated with poor prognosis (J Clin Pathol 2010;63:962), Treatment Comprehensive surgical staging [pathologyoutlines.com]

What is the prognosis for people with ccRCC? The estimate of how a disease will affect you long-term is called prognosis. [cancer.gov]

When recognized, chemotherapy offers a favorable prognosis in patients with choriocarcinoma. Prognosis is poor with other primary malignancies. [meddean.luc.edu]

The prognosis of the condition is generally guarded, since the tumors are aggressive. [dovemed.com]

Prognosis and treatment choices for CCAL may resemble those for common lung cancer, but the prognosis seemed to be better as indicated by median survival data that almost 15.6% and 5% patients could live more than 10, 20 years. [dovepress.com]

It is important to distinguish the different etiologies because treatment varies widely, from observation for granulomas or hamartomas to surgery for malignancies like carcinoid tumor and solitary metastasis. [pulmonologyadvisor.com]

Modern Pathology - Primary Extrapulmonary Sugar Tumor ] Clear-cell tumor of the lung is a rare entity of unknown etiology and histogenesis. This neoplasm typically presents as an asymptomatic, peripheral, sharply rounded mass in the lung. [histopathology-india.net]

Smoking is accepted as the major risk factor, responsible for 70-90% of all cancer cases, although the etiology of lung cancer appears multifactorial with both environmental and genetic factors playing a role. [proteinatlas.org]

Generally arises in peripheral lung, rarely in trachea or bronchi Pathophysiology May rarely arise in patients with tuberous sclerosis along with lymphangioleiomyomatosis (LAM) and micronodular pneumocyte hyperplasia (MMPH) (Am J Surg Pathol 1997;21:1242) Etiology [pathologyoutlines.com]

Patients with CCA and lung adenocarcinoma not otherwise specified (LANOS) were queried from The Surveillance, Epidemiology, and End Results Program (SEER) database. [tlcr.amegroups.com]

Epidemiology The age range is very wide, including children. Only very rarely is there an association with tuberous sclerosis Radiology Lesions are usually solitary and peripheral. [e-immunohistochemistry.info]

Renal Cell Carcinoma Epidemiology Renal Cell Carcinoma Symptoms Renal Cell Carcinoma Diagnosis Renal Cell Carcinoma Risk Factors [news-medical.net]

1971;43:213) Considered a benign PEComa in the lung, as opposed to malignant PEComa ICD coding D14.31 Benign neoplasm of right bronchus and lung D14.32 Benign neoplasm of left bronchus and lung D14.30 Benign neoplasm of unspecified bronchus and lung Epidemiology [pathologyoutlines.com]

Preliminary, Comparative, Randomized, Open Labeled Trial, Evaluating Efficacy and Safety of Add-On Effects More information PATHOPHYSIOLOGICAL PROCESS TEMPLATE 1 PATHOPHYSIOLOGICAL PROCESS TEMPLATE DISEASE: Chronic obstructive pulmonary disease (COPD) [healthdocbox.com]

[…] unspecified bronchus and lung Epidemiology Extremely rare, case reports and small case series Generally older adults >40 years old, may occur in children No clear gender predilection Sites Generally arises in peripheral lung, rarely in trachea or bronchi Pathophysiology [pathologyoutlines.com]

Pathophysiology Histologic criteria for diagnosis of extrapulmonary small cell carcinoma are same as those for pulmonary small cell carcinoma: the presence of uniform small cells with sparse cytoplasm, dense nuclei, and inconspicuous nucleoli. [2] Since [emedicine.medscape.com]

Nagoya, Japan Yoriko Yamashita, Aya Naiki-Ito, Shinya Sato, Shugo Suzuki & Satoru Takahashi Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya, Japan Yoriko Yamashita & Shinya Toyokuni Department of Pathophysiological [nature.com]

The basic function of IVCF was to prevent the passage of larger emboli from the pelvic and lower limb through the inferior vena cava to pulmonary arteries, thus preventing pulmonary embolism. [thefreelibrary.com]

The goal for treatment of a giant cell tumor is to remove the tumor and prevent damage to the affected bone. Tumors that can’t be removed surgically can often be controlled and sometimes destroyed with radiation therapy. [hopkinsmedicine.org]

The goal for treatment of a giant cell tumor is to remove the tumor and prevent bone damage. [cedars-sinai.org]

Treatment for a giant cell tumor almost always involves surgery to remove the tumor and prevent damage to the bone near the affected joint. Giant cell tumors are named for the characteristic way they look when viewed under the microscope. [orthoinfo.aaos.org]