Presentation
The authors present a case of sclerosing hemangioma, a rare benign neoplasm of the lung. The patient presented coughing, blood-tinded spuntum and thoracic pain; chest x-ray showed an irregular shadow close to right hilum. [moh-it.pure.elsevier.com]
We present a very unusual case of giant infantile pulmonary hemangioma presenting as a large solitary pulmonary mass. This was successfully managed with surgical resection. [ncbi.nlm.nih.gov]
We present here two cases of pulmonary sclerosing hemangioma with an unusual clinical presentation. [nature.com]
Entire Body System
- Asymptomatic
Information Publication History Received April 4, 2007 Publication Date: 18 February 2008 (online) Introduction Pulmonary sclerosing hemangioma is a relatively rare lung neoplasm usually presenting as a peripheral and solitary nodule, predominantly in asymptomatic [thieme-connect.com]
Pulmonary sclerosing hemangioma is an unusual lung neoplasm which typically presents as a solitary peripheral nodule in asymptomatic women. Although the histology of this entity is well defined, its origin and treatment is debated. [semanticscholar.org]
She remained asymptomatic for last 10 years and no follow-up visits were done. [cancerjournal.net]
All patients were asymptomatic, and all nodules were detected by computed tomography (CT). The median (range) size of nodule was 11 (8 to 16) mm. [ncbi.nlm.nih.gov]
Its incidence peaks in the fifth decade of life, is often asymptomatic, and is frequently detected as a solitary well-circumscribed nodule on chest X-ray. [kjim.org]
- Swelling
There was no history of pain, ulcers, bleeding in the swellings or history suggestive of paroxysmal nocturnal dyspnea, leg swelling, abdomen distention, palpitation, or chest pain. [amhsjournal.org]
It is important to elevate your head and use cold compresses as much as possible after surgery to reduce the swelling. If the swelling is excessive it could stretch the sutures and cause the eyelid to droop again. [eyeconsultantsofpa.com]
These malformations swell after treatment with alcohol, and the swelling and pain may last for three to five days. During this time, we give patients medication for any pain or swelling they may have. [hopkinsmedicine.org]
[…] neoplasia benign malignant benign non-cancerous, not invasive, does not spread to distant sites, localized tumor that doesnt spread tendrils into surrounding area malignant cancer, can and will spread to distant sites, invasive, aggresive onco- tumor, mass, swelling [proprofs.com]
The eyelid can also droop if weighed down by a large cyst or swelling. What does ptosis surgery involve? Ptosis surgery usually involves shortening the muscles or tendons that raise the lid. [moorfields.nhs.uk]
- Inflammation
[…] and those without inflammation (Table 2). [oatext.com]
Front Back sclero hard itis inflammation imia blood who is affected by cancer old people nephrons having to do with the kidneys/renal septicimia infection of the blood benign non-agressive tumor neoplasm new-growth irreversible cirrhosis often from hepC [proprofs.com]
[…] even chromatin, indistinct nucleoli, and may show cytoplasmic vacuolization, hyperchromasia, pleomorphism May have sclerotic stroma, can be continuous with bronchial epithelium Commonly show hemorrhage, blood lakes, aggregates of histiocytes, chronic inflammation [pathologyoutlines.com]
Treatment options include: Corticosteroid medication: Corticosteroids may be injected into the hemangioma to reduce its growth and to stop inflammation. [healthline.com]
Find treatment plans and drug therapies Mediators of inflammation- Platelets Anzics Offers a detailed outline of a blood platelet disorders and similar conditions. [catsclem.nl]
- Surgical Procedure
PSH can be misdiagnosed as a malignant tumor during intraoperative frozen-section assessment and has a misdiagnosis rate of 25 to 56%, which results in unnecessary extensive surgical procedures and malignant biological behaviors, including local lymph-node [wjso.biomedcentral.com]
Early diagnosis may allow to restrict the surgical procedure and may in some cases even cure the patient, anyhow it prevents complications. Key-words Visceral hemangioma lung newborn This is a preview of subscription content, log in to check access. [link.springer.com]
Early diagnosis may allow to restrict the surgical procedure and may in some cases even cure the patient, anyhow it prevents complications. [documents.tips]
Wikipedia (Eng): Billroth I Surgical Procedures for Primary GIST: Billroth I partial gastrectomy, or gastroduodenostomy BILLROTH II BILLROTH II METHODE BILLROTH'S OPERATION II GASTROJEJUNOSTOMIE GASTROJEJUNOSTOMY Zie ook: MAAGVERWIJDERING MAAGRESECTIE [catsclem.nl]
Respiratoric
- Cough
The patient presented coughing, blood-tinded spuntum and thoracic pain; chest x-ray showed an irregular shadow close to right hilum. A right superior lobectomy was performed. [moh-it.pure.elsevier.com]
Case description A 48-year-old man was referred to our department for further treatment of the productive purulent cough and fever. [springerplus.springeropen.com]
Airway hemangiomas in particular may lead to feeding difficulties, barking cough, stridor, respiratory distress, and even acute airway obstruction. [ncbi.nlm.nih.gov]
The patient's symptoms improved with reductions in coughing, sputum discharge, and hemoptysis involving mostly old clotted blood only. [journals.lww.com]
- Hemoptysis
Pulmonary hemangioma is a rare thoracic condition that can lead to hemoptysis. [ncbi.nlm.nih.gov]
Thus, hemoptysis is a serious complaint in respiratory medicine. [journals.lww.com]
At her return to our department, the patient had recurrent hemoptysis of average abundance associated with very persistent chest pain refractory to analgesics. [omicsonline.org]
Godfrey S (2004) Pulmonary hemorrhage/hemoptysis in children. Pediatr Pulmonol 37: 476-484. [ Crossref ] Pianosi P, al-sadoon H (1996) Hemoptysis in children. [oatext.com]
- Productive Cough
Case description A 48-year-old man was referred to our department for further treatment of the productive purulent cough and fever. [springerplus.springeropen.com]
Gastrointestinal
- Nausea
Some symptoms that indicate you might have an internal hemangioma include: nausea vomiting abdominal discomfort loss of appetite unexplained weight loss a feeling of fullness in the abdomen No special tests are used to diagnose skin hemangiomas. [healthline.com]
Most hepatic hemangiomas are less than 4 cm in diameter; those larger than 4 cm are known as giant hemangiomas. 2 Giant hemangioma may present with abdominal pain or fullness, nausea, hemorrhage with resulting hemodynamic compromise, jaundice due to compression [pulmonarychronicles.com]
Hemoptysis Hematemesis Prodrome of tingling in throat or gurgling in chest Prodrome of nausea and abdominal discomfort Blood coughed out Blood vomited out Frothy, bright red in colour Deep purple, brown or “coffee ground” in colour Mixed with sputum May [oatext.com]
Cardiovascular
- Vascular Disease
You are more likely to have vascular disease as you get older. [icdlist.com]
طرفي peripheral vascular disease تصلب الشرايين Arteriosclerosis تصلب عصيدي Atherosclerosis ( Foam cell, Fatty streak, عصيدة Atheroma, Intermittent claudication ) • Monckeberg's arteriosclerosis • Arteriolosclerosis ( Hyaline, Hyperplastic, oxycholesterol [marefa.org]
Erythrocyte sediment rate (ESR) & C-reactive protein (CRP): Elevated ESR and CRP suggests inflammation either due to infection or collagen vascular disease. RFT/LFT: Chronic liver disease may lead to coagulopathy and PH. [oatext.com]
The bleeding can originate from either small or large vessels within the lung.[4] Hemoptysis has multiple causes commonly classified as parenchymal diseases, airway diseases, and vascular diseases. [journals.lww.com]
Psychiatrical
- Aggressive Behavior
As discussed earlier, aggressive behavior by bronchopulmonary GCT has not been observed. Therefore, conservative therapy for this neoplasm is warranted. [clinicalgate.com]
Neurologic
- Confusion
Whenever there is any confusion regarding lung mass, thoracotomy must be done for arriving at an exact diagnosis from histopathology. Keywords: Lung, sclerosing hemangioma, woman How to cite this article: Saha K, Sit NK, Jash D, Maji A. [cancerjournal.net]
Although epithelioid hemangioendothelioma may exhibit tumor cells with large intracytoplasmic vacuoles, these spaces should not be confused with the expanded vascular channels identified in cavernous hemangioma. [path.upmc.edu]
To avoid misunderstanding and confusion, clarification of terminology for pulmonary vascular lesion is warranted. Fig. 1. Arteriovenous malformation/hemangioma (AVMH) of the lung. [jpatholtm.org]
Other causes: Muscular disorders such as mitochondrial myopathies, myotonic dystrophy, and oculopharyngeal muscular dystrophy Neurotoxic causes such as botulinism or envenomation Ptosis should not be confused with pseudoptosis, which is the perceived [morancore.utah.edu]
Abstract Favorites PDF Get Content & Permissions Open Translation and validation of the Tibetan confusion assessment method for the intensive care unit Danzeng, Qu-Zhen; Cui, Na; Wang, Hao; More Chinese Medical Journal. 132(10):1154-1158, May 20, 2019 [cmj.org]
Workup
However, the majority of new onset HS needs the following radiologic workup: Chest imaging: Plain X-ray or chest CT, with special attention to the lung apices. [reviewofophthalmology.com]
Cannot fully evaluate the magnitude and extent of the hemangioma High vessel density (>5 vessels/cm 2 ) and high peak arterial Doppler shift (>2 kHz) are sensitive and specific for infantile hemangiomas, as compared with other soft tissue masses [7] See Workup [emedicine.medscape.com]
Treatment
Hence, such hemangiomas usually require early and aggressive treatment; however, the treatment modalities employed so far have been associated with their own co-morbidities and potential long-term adverse effects for the developing child. [ncbi.nlm.nih.gov]
Hence, such hemangiomas usually require early and aggressive treatment; however, the treatment modalities employed so far have been associated with their own co‐morbidities and potential long‐term adverse effects for the developing child. [ingentaconnect.com]
After treatment, the patient no longer had hemoptysis. Therefore, in the clinical diagnosis and treatment of patients presenting with hemoptysis, enhanced CT/CT angiography (CTA) is necessary for differential diagnosis. [journals.lww.com]
Laser treatment: Laser treatment is used to remove the hemangioma. In some cases, a surgeon may use laser treatment to reduce redness and promote faster healing. [healthline.com]
Prognosis
[…] alveolar pneumocytes. 5) These tumors are mostly found incidentally on chest radiographs, but some patients may present with chest pain, cough, and hemoptysis. 6) Lymph node metastases have been reported in a few cases but did not seem to affect patient prognosis [histopathology-india.net]
They are treated, if at all, by surgical resection, with an excellent prognosis: generally, the only real danger is the inherent possibility of surgical complications. [en.wikipedia.org]
Based on this case, authors emphasize the need to consider this diagnosis when faced with lung tissue processes with recurrent hemoptysis where the prognosis may be at stake. Case Report The case is about a 27 year old woman, housewife. [omicsonline.org]
Cited by Pulmonary sclerosing pneumocytoma: clinical features and prognosis. Zheng Q, Zhou J, Li G, Man S, Lin Z, Wang T, Chen B, Lin F. Zheng Q, et al. World J Surg Oncol. 2022 Apr 30;20(1):140. doi: 10.1186/s12957-022-02603-4. [pubmed.ncbi.nlm.nih.gov]
Etiology
Sputum for bacteria, fungus and mycobacter: these may provide the etiologic diagnosis in cases of suspected infectious etiology. [oatext.com]
The concerning etiology in these cases is an aneurysm or tumor compressing the nerve, and should be emergently referred for evaluation. [morancore.utah.edu]
In patients over 55 years, the etiology is most likely microvascular and occurs in vasculopaths (hypertensives, diabetics). [reviewofophthalmology.com]
There are different surgical techniques and their indication depends on the etiology and the findings after examinations. It is performed under local anesthesia and sedation in an outpatient basis. [icrcat.com]
Treatment of ptosis depends on age, etiology, whether one or both eyelids are involved, the severity of ptosis, the levator function, and presence of additional ophthalmologic or neurologic abnormalities. [ncbi.nlm.nih.gov]
Epidemiology
[…] originated from morphologic similarity to a dermatopathology lesion that was previously called "sclerosing hemangioma", now known as dermatofibroma / fibrous histiocytoma Also called pneumocytoma, papillary pneumocytoma ( Arch Pathol Lab Med 2009;133:820 ) Epidemiology [pathologyoutlines.com]
[…] sclerosing hemangioma. [2] General Derived from type 2 pneumocyte. [3] Progesterone-receptor positive stromal cells. [4] Rare - 0.2% to 1% of lung tumours. [5] One large series had 100 cases. [6] Management: Surgical excision preferred, may be followed. [5] Epidemiology [librepathology.org]
Epidemiology Mortality/Morbidity Mortality associated with ptosis usually results from anesthetic complications from surgery. [emedicine.medscape.com]
This is consistent with the known epidemiological aspects of peripheral sclerosing hemangioma, occurring predominately in middle-aged females. 2 However, the endobronchial extension is responsible for a peculiar clinical and radiological presentation [nature.com]
Pathophysiology
However, because all of these lesions share a common pathophysiology and natural history, the inclusive term infantile hemangioma is preferred. Symptoms and Signs Superficial lesions have a bright red appearance; deeper lesions have a bluish color. [merckmanuals.com]
Identification of the underlying pathophysiologic mechanism is paramount to institute proper treatment. Pathophysiology Ptosis is the result of dysfunctioning of one or both upper eyelid elevator muscles. [emedicine.medscape.com]
Hypercoagulability related to hematological or neoplastic abnormalities, venous stasis secondary to external compression of IVC by a neighboring pathologic process and vessel injury due to trauma have all been implicated as primary mechanisms in the pathophysiology [pulmonarychronicles.com]
However, the pathophysiology of the association between bronchial papilloma and PSH is unclear. [springerplus.springeropen.com]
Prevention
Video in Spanish How can it be prevented? Ptosis cannot be prevented, but, if detected in time, can be corrected with the appropriate treatment. [imo.es]
There’s no way to prevent droopy eyelid. Just knowing the symptoms and getting a regular eye exam can help you fight the disorder. [healthline.com]