CASE PRESENTATION: A 15-year-old South Asian boy presented with high grade fever, epigastric discomfort and was anicteric on admission. [ncbi.nlm.nih.gov]

• Fever

  Dengue hemorrhagic fever should be considered in the differential diagnosis of diffuse pulmonary hemorrhage. [ncbi.nlm.nih.gov]

  Keywords Dengue virus ; Arthropod borne diseases; Dengue fever; Severe dengue infection; Dengue hemorrhagic fever; Pulmonary hemorrhage; Sri Lanka Abbreviations DF: Dengue Fever; DHF: Dengue Hemorrhagic Fever; SDI: Severe Dengue Infection; BP: Blood Pressure [omicsonline.org]

  Discussion: As per WHO guidelines, our patient fulfilled criteria for DHF: fever of 2-7 days,hemorrhagic tendencies, echhymosis and hemoptysis, thrombocytopenia < 100,000 and other signs of dengue fever like leucopenia and positive IgM. [erj.ersjournals.com]

• Anemia

  Thrombotic microangiopathic hemolytic anemia and anti-phospholipid syndrome can be the presenting manifestations of systemic lupus erythematosus. [ncbi.nlm.nih.gov]

  In a very traditional sense it is described when the following constellation of clinico-radiological features occur simultaneously 2 (although this is never an absolute necessity): hemoptysis anemia air space opacities on imaging Pulmonary hemorrhage [radiopaedia.org]

• Pathologist

  The pathologist's approach to pulmonary hemorrhage is outlined. Most cases fall into those examples of pulmonary hemorrhage caused by localized sites of bleeding, and those examples that fall within the spectrum of diffuse alveolar hemorrhage. [ncbi.nlm.nih.gov]

  Goodpasture’s Syndrome: Goodpasture, a Boston pathologist, was investigating the autopsy findings in influenza pandemic deaths just after World War I. [histopathology-india.net]

  Lung specimens should be read by a pediatric pathologist with expertise in lung disease ( Figure 3 and Figure 4). Figure 3. Histopathologic characteristics of pulmonary capillaritis. [clinicaladvisor.com]

• Hemoptysis

  He had experienced recurrent episodes of massive hemoptysis after epileptic seizures since the age of 28 years. He was admitted to Kyoto University Hospital with massive hemoptysis and hypoxia after an epileptic seizure of a few minutes' duration. [ncbi.nlm.nih.gov]

• Dyspnea

  Pulmonary manifestations of cryoglobulinemia are uncommon and their clinical behaviour is unpredictable, ranging from mild dyspnea to life-threatening presentations. [ncbi.nlm.nih.gov]

  He had a 10 pack-year history of cigarette smoking and quit about one month before presentation due to his progressive dyspnea. He used alcohol on the weekends, but did not use illicit drugs. [the-rheumatologist.org]

  Most patients present with dyspnea, cough, hemoptysis, and new alveolar infiltrates on chest imaging. Diagnostic tests are directed at the suspected cause. [merckmanuals.com]

• Aspiration

  If the Hct is close to the venous Hct, it represents a true hemorrhage, and the blood is usually from trauma, aspiration of maternal blood, or bleeding diathesis. [mhmedical.com]

  Renal biopsy and bone marrow aspiration showed cast nephropathy and an abnormal increase in plasma cells, respectively. She was diagnosed with multiple myeloma and successfully treated with plasma exchange and corticosteroids. [ncbi.nlm.nih.gov]

  This could represent pulmonary edema, pneumonia, aspiration or hemorrhage. The patient had known glomerulonephritis and hemoptysis. [learningradiology.com]

• Rales

  On exam, the patient is diaphoretic and has diffuse bilateral rales in all lung zones. The remainder of the exam is unremarkable. Laboratory tests demonstrate a white blood cell (WBC) count of 36.4, a hemoglobin (Hgb) of 13.1, and a lactate of 2.9. [emdocs.net]

  Sudden tachycardia, tachypnea, hypoxemia, cough, and hemoptysis appeared in the immediate postoperative period, and the patient was transferred to the intensive care unit (ICU) with respiratory failure and generalized coarse rales on admission. [jintensivecare.biomedcentral.com]

• Coarse Rales

  Sudden tachycardia, tachypnea, hypoxemia, cough, and hemoptysis appeared in the immediate postoperative period, and the patient was transferred to the intensive care unit (ICU) with respiratory failure and generalized coarse rales on admission. [jintensivecare.biomedcentral.com]

• Nausea

  A 68-year-old male was seen in the emergency room after an episode of frank hemoptysis associated with oppressive chest pain, nausea, sweating and pallor. Dyspnea, cold sweats and pallor were confirmed on physical examination. [archbronconeumol.org]

  Hemoptysis Hematemesis Prodrome of tingling in throat or gurgling in chest Prodrome of nausea and abdominal discomfort Blood coughed out Blood vomited out Frothy, bright red in colour Deep purple, brown or “coffee ground” in colour Mixed with sputum May [oatext.com]

• Jaundice

  The updated coverage includes new information on fetal assessment, survival of premature infants, and perinatal asphyxia and new guidelines on neonatal jaundice. [books.google.de]

  Higher age at diagnosis, history of hemoptysis or jaundice at presentation was predictive of a partial or poor response to therapy [27]. The long term survival in DAH with various etiologies is presented in table 6 [28]. [oatext.com]

• Hypertension

  Resolution of pulmonary hemorrhage despite anticoagulation while on extracorporeal membrane oxygenation can occur after relief of left atrial hypertension. [ncbi.nlm.nih.gov]

  […] by the arterial hypertension was the cause of pulmonary edema and the ensuing alveolar hemorrhage. [jbsr.be]

• Uremia

  A 70-year-old man with uremia was referred because of hemoptysis. A chest X-ray showed diffuse infiltration in the right lung field. Laboratory data were remarkable for renal failure, anemia, and thrombocytopenia. [ncbi.nlm.nih.gov]

Pulmonary infections are rarely reported in association with DAH, but they should be considered in the diagnostic workup because of the obvious therapeutic implications. [link.springer.com]

• Pulmonary Infiltrate

  Respiratory symptoms and pulmonary infiltrates on chest X-ray were absent upon admission. [ncbi.nlm.nih.gov]

  Criterion C: Diffuse, bilateral pulmonary infiltrates on Chest X-ray (CXR) or Computerized Tomography (CT) of the chest. [cdc.gov]

  A chest roentgenogram showed a recurrence of diffuse, hazy, bilateral pulmonary infiltrates that were similar to those seen earlier. [nejm.org]

  Chest radiographs showed bilateral pulmonary infiltrates occupying all four quadrants, confirmed by chest CT, on the day of admission (Figure 1 ). Figure 1 Chest X-ray and CT scan. (A) Chest X-ray where bilateral pulmonary infiltrates were observed. [jintensivecare.biomedcentral.com]

  The chest x-ray (Figure) showed bilateral pulmonary infiltrates of recent onset and fibrobronchoscopy showed an absence of endobronchial lesions; hemoglobin had decreased by 5 g/dL. [revespcardiol.org]

• Bilateral Pulmonary Infiltrates

  Criterion C: Diffuse, bilateral pulmonary infiltrates on Chest X-ray (CXR) or Computerized Tomography (CT) of the chest. [cdc.gov]

  The chest x-ray (Figure) showed bilateral pulmonary infiltrates of recent onset and fibrobronchoscopy showed an absence of endobronchial lesions; hemoglobin had decreased by 5 g/dL. [revespcardiol.org]

  A chest roentgenogram showed a recurrence of diffuse, hazy, bilateral pulmonary infiltrates that were similar to those seen earlier. [nejm.org]

  Chest radiographs showed bilateral pulmonary infiltrates occupying all four quadrants, confirmed by chest CT, on the day of admission (Figure 1 ). Figure 1 Chest X-ray and CT scan. (A) Chest X-ray where bilateral pulmonary infiltrates were observed. [jintensivecare.biomedcentral.com]

  pulmonary infiltrates on a chest radiograph or computed tomography of the chest. [oatext.com]

• Leukopenia

  A significant drop in hemoglobin and hematocrit levels was observed in association with leukopenia, lymphopenia, a positive ANA, and hypocomplementemia. Chest radiography and computed tomography revealed bilateral infiltrates. [ncbi.nlm.nih.gov]

All of the cases survived after treatment for concurrent VTE and PH, and received short- or long-term anticoagulation treatment after discharge. [ncbi.nlm.nih.gov]

As a cutaneous variant of lupus erythematosus, discoid lupus erythematosus (DLE) is thought to have a good prognosis; however, the involvement of internal organs with a transition to systemic disease may occur. [ncbi.nlm.nih.gov]

Patients with the cryoglobulinemic pulmonary hemorrhage have an extremely poor prognosis and high mortality at presentation and even a poorer prognosis in survivors having further hemorrhagic episodes [ 1 ]. [academic.oup.com]

Considered as a possible etiology, MMF was withdrawn. There was immediate improvement of the patient's symptoms. [ncbi.nlm.nih.gov]

Sputum for bacteria, fungus and mycobacter: these may provide the etiologic diagnosis in cases of suspected infectious etiology. [oatext.com]

/etiology* Humans Infant, Newborn Infant, Premature* Infant, Premature, Diseases/epidemiology Infant, Premature, Diseases/etiology* Infant, Very Low Birth Weight* Male Pennsylvania/epidemiology Prognosis Retrospective Studies Survival Rate/trends [ncbi.nlm.nih.gov]

[…] hemorrhage has been reported to precede DPO in some cases Hemoptysis (see Hemoptysis, [[Hemoptysis]]) Epidemiology : xxx Interstitial Pulmonary Fibrosis (see Interstitial Lung Disease, [[Interstitial Lung Disease]]) Epidemiology : occurs with recurrent [mdnxs.com]

Epidemiology (Sunnyvale) 6:251. doi:10.4172/2161-1165.1000251 Copyright: © 2016 Ralapanawa DMPUK, et al. [omicsonline.org]

London Health Protection Agency (HPA) (2009) Pandemic (H1N1) 2009 in England: an overview of initial epidemiological findings and implications for the second wave. Available at http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1258560552857. [link.springer.com]

The specific pathophysiology and manifestations vary depending on cause. [merckmanuals.com]

On rare occasions pheochromocytoma can present with atypical manifestations such as hemoptysis, acute coronary syndrome with normal coronary catheterization or dilated cardiomyopathy. 1 Pathophysiological mechanisms most often involved in hemoptysis are [archbronconeumol.org]

It is imperative to understand this pathophysiology as many clinical findings are nonspecific and thus, the diagnosis may be difficult to ascertain. (2,7) DAH is characterized by 3 distinct histological types: Pulmonary Capillaritis, Bland Damage, and [emdocs.net]

Negative-pressure pulmonary edema is the result of three pathophysiologic processes: negative intrathoracic pressure, 6 increase of systemic vascular and pulmonary capillary hydrostatic pressure, and mechanical stress at the alveolar–capillary level. [anesthesiology.pubs.asahq.org]

The pathophysiology of leaking in dengue infection is explained by the enhancement of the immune activation, particularly during a secondary infection, leading to exaggerated cytokine response resulting in increased vascular permeability, which is also [omicsonline.org]

Proper prenatal care and preventing premature labor and delivery were the most important preventative factors. A quick, deep thrust of intratracheal epinephrine with a catheter may improve survival. © 2012 The Authors. [ncbi.nlm.nih.gov]

You can help prevent the growth of mold in your home by preventing the conditions that encourage mold growth. [mold-advisor.com]

When this happens, blood leaks into the airways, preventing adequate breathing. Pulmonary hemorrhage can occur with systemic lupus, Goodpasture’s syndrome and Wegener’s granulomatosis. [web.archive.org]