PATIENT SUMMARY: We reviewed outcomes among kidney cancer patients who presented with small lung nodules and developed a clinical tool to predict risk of developing lung metastases. Copyright © 2015 European Association of Urology. [ncbi.nlm.nih.gov]

• Weight Loss

  Herein a previously healthy patient was admitted for dysphagia and fatigue, without significant weight loss. The pathological and molecular tests revealed his diagnosis of BRAF-mutant, advanced PMME with localized pulmonary metastasis. [ncbi.nlm.nih.gov]

  Clinical signs of nematodiasis were vague but generally consisted of weight loss, anorexia, and lethargy. Frequent antemortem fecal examinations were negative for spirurid eggs. [bioone.org]

  She had abdominal pain, occasional fever and weight loss for 3 months. Progressive breathlessness was present for 15 days. Her physical examination was unremarkable. [err.ersjournals.com]

  The symptoms of metastatic lung cancer can include: a persistent cough coughing up blood or bloody phlegm chest pain shortness of breath wheezing weakness sudden weight loss For cancer cells to metastasize, they must go through several changes. [healthline.com]

• Fever

  This 13-year-old girl admitted with 1-year history of cough, intermittent fever, and recurrent hemoptysis. [ncbi.nlm.nih.gov]

  1 Idaigaoka, Yufu-city, Oita, 879-5593 Japan Received: March 17, 2014; Accepted: March 18, 2014; Published: March 19, 2015 Keywords Infiltrative shadow; Lung; Metastasis; Pancreas Clinical Image A 61-year-old female was admitted due to a persistent fever [austinpublishinggroup.com]

  She had abdominal pain, occasional fever and weight loss for 3 months. Progressive breathlessness was present for 15 days. Her physical examination was unremarkable. [err.ersjournals.com]

  At the clinical exam, we note fever at 38°C. [latunisiemedicale.com]

  […] does not go away or gets worse weight loss dyspnea (shortness of breath or difficulty breathing) chest pain, which may be aggravated by deep breathing, coughing, or laughing hemoptysis (coughing up blood or rust-colored phlegm)[7] bone pain clubbing fever [en.wikipedia.org]

• Falling

  A 58-year-old male patient was sent to the emergency room of our hospital because of a sudden fall. Magnetic resonance imaging detected a mass at the right frontal sagittal sinus. [ncbi.nlm.nih.gov]

  […] accordance with its biological characteristics, WHO 2002 has classified desmoids-type fibromatosis as a tumor with the fibroblastic or myo-fibroblastic origin. [2] With respect to its biological status, is referred to as "the intermediate state," which falls [ccij-online.org]

  At presentation, 30–40% of cases of NSCLC are stage IV, and 60% of SCLC are stage IV. [6] Survival for lung cancer falls as the stage at diagnosis becomes more advanced: the English data suggest that around 70% of patients survive at least a year when [en.wikipedia.org]

• Cough

  This 13-year-old girl admitted with 1-year history of cough, intermittent fever, and recurrent hemoptysis. [ncbi.nlm.nih.gov]

  If a lung metastasis does cause symptoms, they may include: pain or discomfort in the lung shortness of breath wheezing persistent cough coughing up blood and mucus It can be difficult to tell the difference between symptoms of lung metastasis and symptoms [breastcancer.org]

  The symptoms of metastatic lung cancer can include: a persistent cough coughing up blood or bloody phlegm chest pain shortness of breath wheezing weakness sudden weight loss For cancer cells to metastasize, they must go through several changes. [healthline.com]

• Hemoptysis

  Three cases of choriocarcinoma with pulmonary metastasis who had the primary symptom of hemoptysis are described. [ncbi.nlm.nih.gov]

  Very rarely are patients symptomatic with cough, pain, hemoptysis, or dyspnea. Helical, thin-sliced computed tomography is the gold standard for detecting pulmonary metastases. [accesssurgery.mhmedical.com]

• Pneumonia

  (mnemonic) acute interstitial pneumonia (AIP) cryptogenic organizing pneumonia (COP) reversed halo / atoll sign desquamative interstitial pneumonia (DIP) idiopathic non-specific interstitial pneumonia (NSIP) fibrotic non-specific interstitial pneumonia [radiopaedia.org]

  Pneumonia-like consolidation  Adenocarcinoma metastases may destroy adjacent lung parenchyma, resulting in pneumonia-like consolidation. 15. [slideshare.net]

  Twenty-two months after completion of radiation therapy, the patient developed a lower left lobe pneumonia. [ecancer.org]

  Crackles can be heard in patients with pneumonia, atelectasis, pulmonary fibrosis, acute bronchitis, bronchiectasis, interstitial lung disease or post thoracotomy or metastasis ablation. [dbpedia.org]

• Rales

  The word "rales" derives from the French word râle meaning "rattle". [dbpedia.org]

  Pulmonary auscultation showed decreased breath sounds, principally in the left lung, with wheezing, diffuse rales and crackles in the lung bases. [scielo.br]

• Dysphagia

  Herein a previously healthy patient was admitted for dysphagia and fatigue, without significant weight loss. The pathological and molecular tests revealed his diagnosis of BRAF-mutant, advanced PMME with localized pulmonary metastasis. [ncbi.nlm.nih.gov]

  Acute toxicities (eg, cough, dyspnea, dysphagia, nausea, and fatigue) were reported in half of the patients treated with whole-lung irradiation. [ascopost.com]

  Acute (0 to 6 months) EBRT side effects include esophagitis, dysphagia, erythema, and a need for tracheostomy, while late complications (6 months to 2 years) include xerostomia, esophageal stenosis, tracheal constriction, carotid stenosis, and brachial [thyroid.org]

  This is caused by compression of vasculature by the lung tumor that restricts blood return from the upper body.[4] dysphagia (trouble swallowing or the sensation that something is caught in the throat) and hoarseness new onset of wheezing without history [en.wikipedia.org]

• Aggressive Behavior

  Recently, some studies provided biomarkers that predicted the aggressive behavior of GCTs of the bone. [healio.com]

  In an article published recently, DFSP with fibrosarcomatous variant is described to have a more aggressive behavior and worse prognosis manifested by a lower recurrence free survival and a greater metastatic potential. 12 Other cases at higher risk of [pagepress.org]

Isolated pulmonary metastasis was defined as limited to presumable pulmonary metastasis according to the follow-up radiologic workup. RESULTS: Thirty-five patients were identified to have repeat pulmonary metastasis. [ncbi.nlm.nih.gov]

[…] an underlying lung cancer at younger ages.[5] Importantly, many of these signs are commonly due to other causes which are not cancer.[6] A detailed medical history should be obtained from each patient to determine the relevance of further diagnostic workup [en.wikipedia.org]

• Pulmonary Infiltrate

  Adem et al. [12] described seven patients with metastatic angiosarcoma presenting with diffuse pulmonary hemorrhage. In four of those patients, chest radiographs showed diffuse pulmonary infiltrates in both lungs. [ajronline.org]

Therefore, early detection, adequate treatment of the primary bone lesion, conservative treatment of lung metastases, and regular long-term follow-up are recommended. Copyright 2016, SLACK Incorporated. [ncbi.nlm.nih.gov]

In this study, by assessing the metastasis pattern, we aimed to identify the factors that may affect prognosis and response to treatment in patients with differentiated thyroid carcinoma (DTC) with pulmonary metastasis. [ncbi.nlm.nih.gov]

Etiology Pulmonary cavities may be the result of malignancy, infection, inflammation, or be congenital: cavitating malignancy primary bronchogenic carcinoma (especially squamous cell carcinoma) cavitating pulmonary metastases squamous cell carcinoma adenocarcinoma [radiopaedia.org]

In contrast to in the situation for breast carcinoma involving women, the etiology of male breast carcinoma remains little understood. [scielo.br]

Since then, efforts to better understand the etiology of PNs in patients with cancer have become necessary. Other series have also found different rates of malignant nodules on histologic analysis of PNs of patients with cancer. [ascopubs.org]

The solitary pulmonary nodule in this case was indistinguishable from pulmonary metastases of the adamantinoma based on clinical symptoms, epidemiology, chest radiography, CT, and FDG-PET/CT. [ncbi.nlm.nih.gov]

Objectives: To review the available data on epidemiology and management of foodborne nematodiasis in the European Union, detect any trends and determine the possible causes of the observed changes. [tandfonline.com]

A population-based epidemiologic and prognostic study of 137 patients. Cancer 1991; 67: 499-505. Mentzel T, Beham A, Katenkamp D, Dei Tos AP, Fletcher CD. [medigraphic.com]

Gestational trophoblastic neoplasia Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Gestational trophoblastic neoplasia from other Diseases Epidemiology and Demographics Risk [wikidoc.org]

The epidemiology will match that of the underlying malignancy (see below), but as malignancies increase in incidence with increasing age, so does the presence of pulmonary metastases. [radiopaedia.org]

In this study, we explored the impact of autophagy on the pathophysiology of breast cancer cells using a novel hypoxia-dependent, reversible dominant-negative strategy to regulate autophagy at the cellular level within the TME. [ncbi.nlm.nih.gov]

Gestational trophoblastic neoplasia Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Gestational trophoblastic neoplasia from other Diseases Epidemiology and Demographics Risk [wikidoc.org]

The presumed underlying pathophysiologic mechanism is excessive vascular production of vasodilators (particularly, nitric oxide). [pubs.rsna.org]

Pathophysiology[edit] The respiratory tract can be divided into two main components: the conducting airways and the gas exchange airways. [en.wikipedia.org]

Bcl-3 could bind to Smad3 and prevent the ubiquitination and degradation of Smad3 protein. These results indicate that Bcl-3 serves as a promising target to prevent breast tumor lung metastasis. [ncbi.nlm.nih.gov]

It’s very difficult to prevent metastatic cancer to the lungs. Researchers are working on preventive treatments, but nothing is common practice yet. [healthline.com]