PATIENT SUMMARY: We reviewed outcomes among kidney cancer patients who presented with small lung nodules and developed a clinical tool to predict risk of developing lung metastases. Copyright © 2015 European Association of Urology. [ncbi.nlm.nih.gov]

• Pain

  Thoracic paravertebral block (TPVB) is a regional anesthetic technique that can relieve pain during and after abdominal or thoracic painful procedures. [ncbi.nlm.nih.gov]

  Liver : Loss of appetite, nausea after eating, or pain under the right ribs can indicate cancer in the liver. Jaundice, a yellowing of the skin and whites of the eyes, is another symptom. [medicalnewstoday.com]

  Original Article The effect of maternal obesity on the success of labor induction with a cervical ripening double-balloon catheter and on pain perception during catheter insertion Tuğba Kınay Berna Dilbaz Runa Özelçi İnci Kahyaoğlu Özlem Moraloğlu Tekin [gulhanemedj.org]

• Weight Loss

  Herein a previously healthy patient was admitted for dysphagia and fatigue, without significant weight loss. The pathological and molecular tests revealed his diagnosis of BRAF-mutant, advanced PMME with localized pulmonary metastasis. [ncbi.nlm.nih.gov]

  Clinical signs of nematodiasis were vague but generally consisted of weight loss, anorexia, and lethargy. Frequent antemortem fecal examinations were negative for spirurid eggs. [bioone.org]

  She had abdominal pain, occasional fever and weight loss for 3 months. Progressive breathlessness was present for 15 days. Her physical examination was unremarkable. [err.ersjournals.com]

  The symptoms of metastatic lung cancer can include: a persistent cough coughing up blood or bloody phlegm chest pain shortness of breath wheezing weakness sudden weight loss For cancer cells to metastasize, they must go through several changes. [healthline.com]

• Surgical Procedure

  Six of these patients underwent delayed treatment, locally aggressive, or multiple recurrent and surgical procedures. All of the aforementioned procedures had similar risk factors to those previously reported in the literature. [ncbi.nlm.nih.gov]

  Wedge resection (35, 22 of which through VATS procedures) was the most frequent surgical procedure performed. Ten were the segmental resections and 9 the lobectomies, all of these performed with a thoracotomy. [intechopen.com]

  In 2005, he underwent a wide local excision surgical procedure of a tumor lesion in his left arm which was diagnosed as DFSP and treated with post-surgical adjuvant radiotherapy (60 Gy dose). [pagepress.org]

  Other factors including sex, clinical stage, lymphovascular invasion, surgical procedure, neoadjuvant/adjuvant treatment and tumour differentiation were not associated with pulmonary recurrence. [bmjopen.bmj.com]

• Fever

  This 13-year-old girl admitted with 1-year history of cough, intermittent fever, and recurrent hemoptysis. [ncbi.nlm.nih.gov]

  1 Idaigaoka, Yufu-city, Oita, 879-5593 Japan Received: March 17, 2014; Accepted: March 18, 2014; Published: March 19, 2015 Keywords Infiltrative shadow; Lung; Metastasis; Pancreas Clinical Image A 61-year-old female was admitted due to a persistent fever [austinpublishinggroup.com]

  She had abdominal pain, occasional fever and weight loss for 3 months. Progressive breathlessness was present for 15 days. Her physical examination was unremarkable. [err.ersjournals.com]

  At the clinical exam, we note fever at 38°C. [latunisiemedicale.com]

  […] does not go away or gets worse weight loss dyspnea (shortness of breath or difficulty breathing) chest pain, which may be aggravated by deep breathing, coughing, or laughing hemoptysis (coughing up blood or rust-colored phlegm)[7] bone pain clubbing fever [en.wikipedia.org]

• Cough

  This 13-year-old girl admitted with 1-year history of cough, intermittent fever, and recurrent hemoptysis. [ncbi.nlm.nih.gov]

  If a lung metastasis does cause symptoms, they may include: pain or discomfort in the lung shortness of breath wheezing persistent cough coughing up blood and mucus It can be difficult to tell the difference between symptoms of lung metastasis and symptoms [breastcancer.org]

  The symptoms of metastatic lung cancer can include: a persistent cough coughing up blood or bloody phlegm chest pain shortness of breath wheezing weakness sudden weight loss For cancer cells to metastasize, they must go through several changes. [healthline.com]

• Hemoptysis

  Three cases of choriocarcinoma with pulmonary metastasis who had the primary symptom of hemoptysis are described. [ncbi.nlm.nih.gov]

  Very rarely are patients symptomatic with cough, pain, hemoptysis, or dyspnea. Helical, thin-sliced computed tomography is the gold standard for detecting pulmonary metastases. [accesssurgery.mhmedical.com]

• Pleural Effusion

  A pediatric osteosarcoma with pulmonary metastasis and malignant pleural effusion. Osteosarcoma with pulmonary metastasis and malignant pleural effusion. [ncbi.nlm.nih.gov]

   Chest X-ray  Coarse, linear, reticular and nodular basal shadowing often with pleural effusions and hilar lymphadenopathy. 21. [slideshare.net]

  Pleural metastases are seen as nodularities, a plaquelike formation on the pleural surface with or without associated pleural effusion. [emedicine.medscape.com]

  The usual pattern of PM involved multiple pulmonary nodules in 65 patients (72%); solitary pulmonary nodules were found in 16 (18%), mass lesion in 10 (11%), lymphangitic spread in 3, and pleural effusion in 6 (6.7%). [karger.com]

• Pneumonia

  (mnemonic) acute interstitial pneumonia (AIP) cryptogenic organizing pneumonia (COP) reversed halo / atoll sign desquamative interstitial pneumonia (DIP) idiopathic non-specific interstitial pneumonia (NSIP) fibrotic non-specific interstitial pneumonia [radiopaedia.org]

  Pneumonia-like consolidation  Adenocarcinoma metastases may destroy adjacent lung parenchyma, resulting in pneumonia-like consolidation. 15. [slideshare.net]

  Twenty-two months after completion of radiation therapy, the patient developed a lower left lobe pneumonia. [ecancer.org]

  Crackles can be heard in patients with pneumonia, atelectasis, pulmonary fibrosis, acute bronchitis, bronchiectasis, interstitial lung disease or post thoracotomy or metastasis ablation. [dbpedia.org]

• Malignant Pleural Effusion

  A pediatric osteosarcoma with pulmonary metastasis and malignant pleural effusion. Osteosarcoma with pulmonary metastasis and malignant pleural effusion. [ncbi.nlm.nih.gov]

  Pleural metastases are seen as nodularities, a plaquelike formation on the pleural surface with or without associated pleural effusion. [emedicine.medscape.com]

• Nausea

  Headaches, confusion, tiredness, nausea, and weakness are symptoms. Liver : Loss of appetite, nausea after eating, or pain under the right ribs can indicate cancer in the liver. [medicalnewstoday.com]

  Acute toxicities (eg, cough, dyspnea, dysphagia, nausea, and fatigue) were reported in half of the patients treated with whole-lung irradiation. [ascopost.com]

  It is also important to know that pain, nausea, and other side effects can be managed with the help of your health care team. This is called palliative care and should be a part of any treatment plan. [cancer.net]

  Common side effects of many chemotherapy drugs are low blood cell counts (called bone marrow suppression), nausea and vomiting, mouth problems and bowel problems. Find out more about chemotherapy and side effects of chemotherapy. [cancer.ca]

• Dysphagia

  Herein a previously healthy patient was admitted for dysphagia and fatigue, without significant weight loss. The pathological and molecular tests revealed his diagnosis of BRAF-mutant, advanced PMME with localized pulmonary metastasis. [ncbi.nlm.nih.gov]

  Acute toxicities (eg, cough, dyspnea, dysphagia, nausea, and fatigue) were reported in half of the patients treated with whole-lung irradiation. [ascopost.com]

  Acute (0 to 6 months) EBRT side effects include esophagitis, dysphagia, erythema, and a need for tracheostomy, while late complications (6 months to 2 years) include xerostomia, esophageal stenosis, tracheal constriction, carotid stenosis, and brachial [thyroid.org]

  This is caused by compression of vasculature by the lung tumor that restricts blood return from the upper body.[4] dysphagia (trouble swallowing or the sensation that something is caught in the throat) and hoarseness new onset of wheezing without history [en.wikipedia.org]

• Aggressive Behavior

  Recently, some studies provided biomarkers that predicted the aggressive behavior of GCTs of the bone. [healio.com]

  In an article published recently, DFSP with fibrosarcomatous variant is described to have a more aggressive behavior and worse prognosis manifested by a lower recurrence free survival and a greater metastatic potential. 12 Other cases at higher risk of [pagepress.org]

Isolated pulmonary metastasis was defined as limited to presumable pulmonary metastasis according to the follow-up radiologic workup. RESULTS: Thirty-five patients were identified to have repeat pulmonary metastasis. [ncbi.nlm.nih.gov]

[…] an underlying lung cancer at younger ages.[5] Importantly, many of these signs are commonly due to other causes which are not cancer.[6] A detailed medical history should be obtained from each patient to determine the relevance of further diagnostic workup [en.wikipedia.org]

• Pulmonary Infiltrate

  Adem et al. [12] described seven patients with metastatic angiosarcoma presenting with diffuse pulmonary hemorrhage. In four of those patients, chest radiographs showed diffuse pulmonary infiltrates in both lungs. [ajronline.org]

• Pleural Effusion

  A pediatric osteosarcoma with pulmonary metastasis and malignant pleural effusion. Osteosarcoma with pulmonary metastasis and malignant pleural effusion. [ncbi.nlm.nih.gov]

   Chest X-ray  Coarse, linear, reticular and nodular basal shadowing often with pleural effusions and hilar lymphadenopathy. 21. [slideshare.net]

  Pleural metastases are seen as nodularities, a plaquelike formation on the pleural surface with or without associated pleural effusion. [emedicine.medscape.com]

  The usual pattern of PM involved multiple pulmonary nodules in 65 patients (72%); solitary pulmonary nodules were found in 16 (18%), mass lesion in 10 (11%), lymphangitic spread in 3, and pleural effusion in 6 (6.7%). [karger.com]

Therefore, early detection, adequate treatment of the primary bone lesion, conservative treatment of lung metastases, and regular long-term follow-up are recommended. Copyright 2016, SLACK Incorporated. [ncbi.nlm.nih.gov]

In this study, by assessing the metastasis pattern, we aimed to identify the factors that may affect prognosis and response to treatment in patients with differentiated thyroid carcinoma (DTC) with pulmonary metastasis. [ncbi.nlm.nih.gov]

Etiology Pulmonary cavities may be the result of malignancy, infection, inflammation, or be congenital: cavitating malignancy primary bronchogenic carcinoma (especially squamous cell carcinoma) cavitating pulmonary metastases squamous cell carcinoma adenocarcinoma [radiopaedia.org]

In contrast to in the situation for breast carcinoma involving women, the etiology of male breast carcinoma remains little understood. [scielo.br]

Since then, efforts to better understand the etiology of PNs in patients with cancer have become necessary. Other series have also found different rates of malignant nodules on histologic analysis of PNs of patients with cancer. [ascopubs.org]

The solitary pulmonary nodule in this case was indistinguishable from pulmonary metastases of the adamantinoma based on clinical symptoms, epidemiology, chest radiography, CT, and FDG-PET/CT. [ncbi.nlm.nih.gov]

Objectives: To review the available data on epidemiology and management of foodborne nematodiasis in the European Union, detect any trends and determine the possible causes of the observed changes. [tandfonline.com]

A population-based epidemiologic and prognostic study of 137 patients. Cancer 1991; 67: 499-505. Mentzel T, Beham A, Katenkamp D, Dei Tos AP, Fletcher CD. [medigraphic.com]

Gestational trophoblastic neoplasia Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Gestational trophoblastic neoplasia from other Diseases Epidemiology and Demographics Risk [wikidoc.org]

The epidemiology will match that of the underlying malignancy (see below), but as malignancies increase in incidence with increasing age, so does the presence of pulmonary metastases. [radiopaedia.org]

In this study, we explored the impact of autophagy on the pathophysiology of breast cancer cells using a novel hypoxia-dependent, reversible dominant-negative strategy to regulate autophagy at the cellular level within the TME. [ncbi.nlm.nih.gov]

Gestational trophoblastic neoplasia Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Gestational trophoblastic neoplasia from other Diseases Epidemiology and Demographics Risk [wikidoc.org]

The presumed underlying pathophysiologic mechanism is excessive vascular production of vasodilators (particularly, nitric oxide). [pubs.rsna.org]

Pathophysiology[edit] The respiratory tract can be divided into two main components: the conducting airways and the gas exchange airways. [en.wikipedia.org]

Bcl-3 could bind to Smad3 and prevent the ubiquitination and degradation of Smad3 protein. These results indicate that Bcl-3 serves as a promising target to prevent breast tumor lung metastasis. [ncbi.nlm.nih.gov]

It’s very difficult to prevent metastatic cancer to the lungs. Researchers are working on preventive treatments, but nothing is common practice yet. [healthline.com]