Presentation
We describe a case of secondary syphilis with pulmonary involvement and we present a literature review. A 69-year-old male patient was admitted to hospital for dyspnoea and extended papular exanthema with palmoplantar involvement. [ncbi.nlm.nih.gov]
Abstract A 39-year-old Japanese man presented to our hospital complaining of left chest pain and rash on the hands and feet. Plain thoracic computed tomography (CT) revealed multiple nodular shadows in the left lower lobe of the lung. [jstage.jst.go.jp]
Over 20 NEW test entries present the latest tests and procedures, with a strong focus on affordable, clinically relevant genetic tests. [books.google.de]
Genital mucus lesions typically occur in women and present as condylomata, ulcerations, or papules. [emdocs.net]
Neurosyphilis can present at any stage of the disease. [consultqd.clevelandclinic.org]
Entire Body System
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Collapse
Sometimes, with the collapse of large gum provide radiological picture resembling lung abscess with a small amount of fluid in the cavity. Diagnosis helps serology - strongly positive Wassermann reaction The research of sputum to exclude TB. [eurodoctor.ucoz.com]
[…] diseases affections affusions afterwards appear application attack attended bleeding blisters blood blood-letting bowels brain bronchia calomel capillary cause chest chronic congestion chronic diseases chronic inflammation circulation circumstances cold collapse [books.google.de]
Symptoms include [4] blunted upper incisor teeth known as Hutchinson's teeth inflammation of the cornea known as interstitial keratitis deafness from auditory nerve disease frontal bossing (prominence of the brow ridge) saddle nose (collapse of the bony [en.wikipedia.org]
Observations showed a blood pressure of 157/66 mmHg, pulse of 86 beats per minute (collapsing in nature), and jugular venous pressure was normal. She had normal first heart sound with an early diastolic murmur. [bjcardio.co.uk]
Acute vertebral collapse and cauda equina compression in tertiary syphilis. J Neurol Neurosurg Psychiatry. 1975;38(6):558–60. View Article PubMed PubMed Central Google Scholar Ramani PS, Sengupta RP. [bmcinfectdis.biomedcentral.com]
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Prostitute
Summarized by the mnemonic PARESIS: P Personality changes A Affect R Reflexes (hyperreflexia) E Eye (Argyll Robertson Pupil – reacts to accommodation, not light – aka “Prostitute’s Pupil”) S Sensorium – hallucinations, delusions I Intellect decreased [errolozdalga.com]
The Communist party cracked down on prostitution as well, which resulted in a near elimination of syphilis [2]. [microbewiki.kenyon.edu]
Respiratoric
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Sputum
Diagnosis helps serology - strongly positive Wassermann reaction The research of sputum to exclude TB. The clinical picture of syphilis of the lungs has no special features. [eurodoctor.ucoz.com]
Gastrointestinal
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Hematochezia
Haug Browse recently published Learning/CME Learning/CME View all learning/CME CME Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis Case 4-2019: An 18-Year-Old Man with Abdominal Pain and Hematochezia Bridging the Gap Challenge Yourself [nejm.org]
Musculoskeletal
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Contusion
Manifestations of Pulmonary Tuberculosis in CT Imaging Outcome in patients with blunt chest trauma and pulmonary contusions Hematogenous Panophthalmitis Inhibition of the Oversensing of Cardiac Pacemakers in Chest CT 更多... [oalib.com]
Skin
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Rash of the Hands and Feet
Abstract A 39-year-old Japanese man presented to our hospital complaining of left chest pain and rash on the hands and feet. Plain thoracic computed tomography (CT) revealed multiple nodular shadows in the left lower lobe of the lung. [jstage.jst.go.jp]
Face, Head & Neck
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Leontiasis
(malignant) (membranous) (phlegmonous) (pneumococcal) (pseudomembranous) (septic) (subglottic) (suppurative) (ulcerative) (viral) 464.00 syphilitic 095.8 Laryngotracheitis (acute) (infectional) (viral) (see also Laryngitis) 464.20 syphilitic 095.8 Leontiasis [icd9data.com]
Workup
In the absence of x-ray findings, workup becomes more problematic. [aao.org]
X-Ray
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Multiple Pulmonary Nodules
Chest CT scan and 18 F-fluorodeoxyglucose (FDG) PET/CT showed multiple pulmonary nodules mimicking pulmonary hematogenous metastases. This was confirmed on follow-up images that showed therapeutic response to penicillin. [oalib.com]
All of these cases presented with multiple pulmonary nodules. The association of pulmonary nodules with the characteristic skin lesions may aid diagnosis and the early institution of treatment. Footnotes Conflict of interest: None declared. [err.ersjournals.com]
A case of secondary syphilis presenting as multiple pulmonary nodules. Korean J Intern Med 2013;28:231–235. 36. Holland BA, Perrett LV, Mills CM. Meningovascular syphilis: CT and MR findings. Radiology 1986;158:439–442. 37. [synapse.koreamed.org]
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Atelectasis
Surgical intervention is indicated for the irreversible effects of syphilis: the persistent cicatricial changes with the formation of bronchial stenosis or atelectasis bronchial bronchiectasis. With this material are reading... [eurodoctor.ucoz.com]
Treatment
Treatment with intravenous penicillin G was effective on cutaneous, ocular and pulmonary manifestations. Lung involvement in secondary syphilis is poorly known and rarely described. [ncbi.nlm.nih.gov]
Protivosifiliticheskoe treatment administered without prior administration of iodine and biyohinola. [eurodoctor.ucoz.com]
This excellent reference book is designed to be a concise textbook of the treatment of diseases of the respiratory tract. Dr. [books.google.de]
Prognosis
He gives the definition, aetiology, pathology, symptoms, physical signs, complications, diagnosis, prognosis, general treatment and the proven Homeopathic remedies that have been found to be the most useful, for over thirty specific diseases including [books.google.de]
[…] favorable prognosis for patients diagnosed with either primary or secondary syphilis 20% of untreated patients with tertiary syphilis die of the disease prognosis for tertiary syphilis depends on the extent of scarring and tissue damage with adequate [medbullets.com]
Outlook (Prognosis) Primary and secondary syphilis can be cured if it is diagnosed early and completely treated. Although secondary syphilis usually goes away within weeks, in some cases it may last for up to 1 year. [mountsinai.org]
The prognosis depends on how early it is caught and treated. [draxe.com]
Etiology
Etiology The differential for etiologies of pulmonary artery aneurysms can be broad. [radiopaedia.org]
A review of the literature suggested the etiology of PAAs can be congenital or acquired. Congenital aneurysms are usually associated with cardiac malformations causing pulmonary hypertension, and persistent ductus arteriosus is the most frequent. [revespcardiol.org]
Epidemiology
Epidemiology, Clinical Features, and Laboratory Diagnosis Infection of the fetus will occur in 40%-50% of pregnant women who have primary or active syphilis. [isradiology.org]
Rolfs RT, Nakashima AK (1990) Epidemiology of primary and secondary syphilis in the United States, 1981 to 1989. JAMA 264: 1432 PubMed Google Scholar 4. [link.springer.com]
Skin -rhagades(cracks, fissures atmucocutaneousjunctions) #1, 2, & 3 are part of Hutchinson’s triad Extended discussion Epidemiology (Treponema Pallidum): Transmitted at any time during pregnancy or at birth Transmitted at any disease stage Almost 100% [johnsarm.net]
Epidemiology, treatment and molecular typing of Treponema pallidum. Dan Med J. 2015 Dec;62(12):B [emdocs.net]
Introduction Classification Treponema pallidum spirochete Epidemiology demographics most common during years of peak sexual activity most new cases occur in men and women aged 20-29 years recent rise in syphilis cases among men who have sex with men [medbullets.com]
Pathophysiology
It is not clear of the pathophysiology mechanism for such changes. The formation of chronic gummas is the character of gummatous syphilis. [bmcinfectdis.biomedcentral.com]
Prevention
Nurses are key in efforts of secondary prevention, ensuring that proper screening takes place. [americannursetoday.com]
"A Brief Introduction to the National Center for AIDS Prevention and Control, China CDC." National Center for AIDS/STD Control and Prevention, China CDC. NCAIDS. 26 Aug 2009 . [12]. "Prevention and Treatment of Infectious Diseases." [microbewiki.kenyon.edu]
Treatment is needed to cure a syphilis infection, prevent complications, and prevent the spread of the infection to others. [bccdc.ca]
Encyclopedia) RPR test (Medical Encyclopedia) Syphilis (Centers for Disease Control and Prevention) Syphilis - primary (Medical Encyclopedia) Syphilis and MSM (Men Who Have Sex with Men) (Centers for Disease Control and Prevention) VDRL test (Medical [icdlist.com]
Preventing STDs Because syphilis is an STD, the best way to prevent getting it is to abstain from having sex. Sexual activity with more than one partner or with someone who has more than one sex partner also increases the risk of contracting an STD. [connecticutchildrens.org]