[…] until after puberty begins, [44] Hidradenitis suppurativa is not present in eunuchs or eunuchoids, and hidradenitis suppurativa may occur as the presenting feature of premature adrenarche. [45] Also, antiandrogen therapy is of some benefit in patients [emedicine.medscape.com]

See Workup for more detail. [emedicine.medscape.com]

[…] and effectiveness for hidradenitis suppurativa treatment. [emedicine.medscape.com]

Successful treatment of superficial pyoderma gangrenosum associated with hidradenitis suppurativa with adalimumab. Dermatol Online J 2010;16:15. Saraceno R, Babino G, Chiricozzi A et al. [hs-online.be]

Risk factors, clinical course and long-term prognosis in hidradenitis suppurativa: a cross-sectional study. Br J Dermatol 2014;171:819–24. Shlyankevich J, Chen AJ, Kim GE et al. [hs-online.be]

No single treatment has shown overwhelmingly positive outcomes. [60] Spontaneous resolution is rare. [7] Specific factors appear to influence the prognosis. Larger excisions may offer a better outcome. [emedicine.medscape.com]

Etiology of Hidradenitis Suppurativa The exact etiology of hidradenitis suppurativa remains obscure. [emedicine.medscape.com]

Moreover, epidemiological data also suggest an association of hidradenitis suppurativa with other diseases, including metabolic syndrome. [emedicine.medscape.com]

Pathophysiology Hidradenitis suppurativa (HS) has traditionally been considered a disorder of the apocrine glands. [emedicine.medscape.com]