With variation present between disease presentations from case to case, it is possible that the spectrum of PAPA syndrome is wider than currently thought. [ncbi.nlm.nih.gov]

[…] on Admission - Yes) Total Medicare Hospitalizations - Oct 2015 to Sep 2018 (Present on Admission - Yes) Total National Projected Hospitalizations - Annualized (Present on Admission - Not Y) Total Medicare Hospitalizations - Oct 2015 to Sep 2018 (Present [dexur.com]

• Fever

  [ 713.6 ] Staphylococcus 711.0 Streptococcus 711.0 syphilis (see also Syphilis) 094.0 [ 711.4 ] syringomyelia 336.0 [ 713.5 ] thalassemia (see also Thalassemia) 282.40 [ 713.2 ] tuberculosis (see also Tuberculosis, arthritis) 015.9 [ 711.4 ] typhoid fever [icd9data.com]

  Such patients presenting with unexplained fever of more than 1 degrees C(1.8 degrees F) and acute symptoms of joint inflammation should have an arthrocentesis. [ncbi.nlm.nih.gov]

  Fever of undetermined origin in patients with the acquired immunodeficiency syndrome in Brazil: report on 55 cases. [scielo.br]

• Swelling

  Calf swelling and tenderness with apparent antibiotic resistance in pyogenic arthritis of the knee are the major signs of the diagnosis. [ncbi.nlm.nih.gov]

  Although conventional radiographs are obtained as the initial study, they are relatively insensitive to the early findings of the disease except for soft tissue swelling and osteopenia. [learningradiology.com]

  Infectious Arthritis Also called: Septic arthritis Most kinds of arthritis cause pain and swelling in your joints. Joints are places where two bones meet, such as your elbow or knee. Infectious arthritis is an infection in the joint. [icdlist.com]

• Chronic Diarrhea

  […] joints, buttocks, and scrotum, and chronic diarrhea. [ncbi.nlm.nih.gov]

Magnetic resonance imaging (MRI) has no role in the initial workup. The use of this expensive and time-consuming modality should be reserved for situations in which simpler measures, such as joint aspiration, fail to provide a diagnosis. [emedicine.com]

[…] hr US - Effusion Effusion Joint Aspiration IV Antibiotics Admit Ortho* OR Admit Pediatrics Equivocal Septic Arthritis Afebrile Decreased Range of Motion Limp Labs, X-rays - - US Ortho Consult Consider Aspiration Consider admit Pediatrics for further workup [chop.edu]

Diagnostic Workup Diagnostic workup begins with a high index of suspicion, and should include standard and advanced imaging techniques, laboratory studies, and diagnostic aspirations. [clinicaladvisor.com]

• Muscle Calcification

  On admission, an enhanced abdominal computed tomography scan showed an abnormal increase in synovial fluid surrounding the right ilium, with piriformis muscle calcification. [ncbi.nlm.nih.gov]

Abstract This study reports the clinical results of treatment for injection-induced pyogenic arthritis of the shoulder joint. [ncbi.nlm.nih.gov]

Patients with a positive culture from the hip or shoulder who had been pretreated with antibiotics had the worst prognosis. [ncbi.nlm.nih.gov]

Physicians should be aware that a delayed diagnosis results in a worse prognosis. [synapse.koreamed.org]

With adequate management the prognosis of suppurative sacroiliitis in pediatric patients is excellent, despite persistent abnormal radiographic findings in most patients. Received November 1, 1979. Accepted December 21, 1979. [pediatrics.aappublications.org]

Recent reports using a staging system based on arthroscopic findings have proven that the prognosis worsens as the stage advances [ 10, 11 ]. [doi.org]

Successful identification of a single disease locus for this syndrome suggests that these clinically distinct disorders may share a genetic etiology. [ncbi.nlm.nih.gov]

Joint aspiration under biplane fluoroscopic control and culture of the aspirated material is indicated in establishing the specific etiologic agent which is Staphylococcus aureus in most cases. [pediatrics.aappublications.org]

Etiology The gene responsible for the syndrome, the proline-serine-threonine phosphatase interacting protein 1 ( PSTPIP1 ) gene (previously known as the CD2 binding protein 1 ( CD2BP1 ) gene), was cloned in 2002. [orpha.net]

OBJECTIVE: To study the epidemiological characteristics and predictors of treatment outcomes for Thai patients hospitalized with PA. MATERIALS AND METHODS: The nationwide hospital database from the 2010 fiscal year was analyzed. [ncbi.nlm.nih.gov]

Objective To study the epidemiological characteristics and predictors of treatment outcomes for Thai patients hospitalized with PA. Materials and methods The nationwide hospital database from the 2010 fiscal year was analyzed. [onlinelibrary.wiley.com]

Summary Epidemiology To date, only 34 patients with PAPA syndrome have been reported worldwide, from five families (two in the USA, one in Italy, one in the Netherlands, and one in New Zealand). [orpha.net]

Patient Population: Prevalence and Epidemiology Knee // Shoulder & Elbow // Hip // Spine // Foot & Ankle // Hand & Wrist Fragility Fractures: Diagnosis and Treatment Shoulder & Elbow The Characteristics of Surgeons Performing Total Shoulder Arthroplasty [mdedge.com]

Clinical, epidemiological, and therapeutic data on pediatric PG is poor as there are many newly reported associated diseases and drugs. This paper aims to review all recent available data on pediatric PG. [read.qxmd.com]

However, the pathophysiological function of PSTPIP1 remains to be elucidated. We have generated mouse strains that either are PSTPIP1 deficient or ectopically express mutant PSTPIP1. [ncbi.nlm.nih.gov]

Disseminated gonococcal infection: a prospective analysis of 49 patients and a review of pathophysiology and immune mechanisms. Medicine. 1983;62:395. PubMed CrossRef Google Scholar 14. Herndon WA, Knauer S, Sullivan JA, et al. [link.springer.com]

The pathophysiology of septic arthritis – or how the disease occurs – is when organisms such as viruses, bacteria, or fungi enter the joint space directly (as in the case of an injury or injection that breaks the skin) or through the bloodstream from [joybauer.com]

The purpose of this article is to provide an overview of the pathophysiology, diagnosis, treatment and long-term follow-up of septic arthritis in children. Figure 1. [racgp.org.au]

Surgery related Simultaneous bilateral arthroplasty Operative time 2.5 hours Allogenic blood transfusion Postoperative complications Delayed wound healing Atrial fibrillation Myocardial infarction Urinary tract infection (UTI) Prolonged hospital stay Pathophysiology [arupconsult.com]

Preventive measures directed to patients with prosthetic joints or osteosynthetic material, and a known haematogenous source would have prevented at most 8% of all cases. bacterial arthritis prosthetic joint infection epidemiology prevention Statistics [doi.org]

Chapter 16: Patient-Centered Care -- Chapter 17: Harnessing Data to Make Quality Improvement Decisions: Measurement and Measures -- Chapter 18: Standardization and Reliability -- Chapter 19: Tools to Identify Problems and Reduce Risks -- Chapter 20: Preventing [worldcat.org]

Postoperative physiotherapy and mobilisation of the joint is necessary, while splinting prevents contractures. Early treatment may prevent severe complications such as dislocation, acvascular necrosis and late osteoarthritis. [www0.sun.ac.za]

Therefore, timely and correct diagnosis with early treatment is critical to preventing acute complications and late sequelae. [spandidos-publications.com]

Preventive (prophylactic) antibiotics may be helpful for people at high risk. Bacterial arthritis; Non-gonococcal bacterial arthritis Cook PP, Siraj DS. Bacterial arthritis. In: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. [nlm.nih.gov]