With variation present between disease presentations from case to case, it is possible that the spectrum of PAPA syndrome is wider than currently thought. [ncbi.nlm.nih.gov]

[…] on Admission - Yes) Total Medicare Hospitalizations - Oct 2015 to Sep 2018 (Present on Admission - Yes) Total National Projected Hospitalizations - Annualized (Present on Admission - Not Y) Total Medicare Hospitalizations - Oct 2015 to Sep 2018 (Present [dexur.com]

The incidence of anemia correlated with delayed presentation, a higher rate in patients that presented later than 6 days compared to the ones that presented earlier (64.5% vs. 15.4% P < 0.003) was observed. [nigerianjsurg.com]

Nongonococcal arthritis presents with a hot swollen joint that is painful throughout passive and active range of motion. Fever and signs of sepsis may also be present. Pain is present on both passive and active range of motion. [radiologykey.com]

• Fever

  [ 713.6 ] Staphylococcus 711.0 Streptococcus 711.0 syphilis (see also Syphilis) 094.0 [ 711.4 ] syringomyelia 336.0 [ 713.5 ] thalassemia (see also Thalassemia) 282.40 [ 713.2 ] tuberculosis (see also Tuberculosis, arthritis) 015.9 [ 711.4 ] typhoid fever [icd9data.com]

  Such patients presenting with unexplained fever of more than 1 degrees C(1.8 degrees F) and acute symptoms of joint inflammation should have an arthrocentesis. [ncbi.nlm.nih.gov]

  Fever of undetermined origin in patients with the acquired immunodeficiency syndrome in Brazil: report on 55 cases. [scielo.br]

  […] the infected joint (pseudoparalysis) Severe joint pain Joint swelling Joint redness Fever Chills may occur, but are uncommon. [nlm.nih.gov]

• Swelling

  Calf swelling and tenderness with apparent antibiotic resistance in pyogenic arthritis of the knee are the major signs of the diagnosis. [ncbi.nlm.nih.gov]

  Although conventional radiographs are obtained as the initial study, they are relatively insensitive to the early findings of the disease except for soft tissue swelling and osteopenia. [learningradiology.com]

  Infectious Arthritis Also called: Septic arthritis Most kinds of arthritis cause pain and swelling in your joints. Joints are places where two bones meet, such as your elbow or knee. Infectious arthritis is an infection in the joint. [icdlist.com]

  […] route of infection is hemic to the synovial tissue, causing destruction of the articular cartilage; may become chronic, with sinus formation, osteomyelitis, deformity, and disability. bacterial arthritis An acute arthropathy characterised by painful swelling [medical-dictionary.thefreedictionary.com]

• Chronic Diarrhea

  […] joints, buttocks, and scrotum, and chronic diarrhea. [ncbi.nlm.nih.gov]

+ - Effusion Effusion Joint Aspiration IV Antibiotics Admit Ortho* OR Admit Pediatrics Equivocal Septic Arthritis Afebrile Decreased Range of Motion Limp Labs, X-rays + - + - US Ortho Consult Consider Aspiration Consider admit Pediatrics for further workup [chop.edu]

Magnetic resonance imaging (MRI) has no role in the initial workup. The use of this expensive and time-consuming modality should be reserved for situations in which simpler measures, such as joint aspiration, fail to provide a diagnosis. [emedicine.com]

Diagnostic Workup Diagnostic workup begins with a high index of suspicion, and should include standard and advanced imaging techniques, laboratory studies, and diagnostic aspirations. [clinicaladvisor.com]

• Muscle Calcification

  On admission, an enhanced abdominal computed tomography scan showed an abnormal increase in synovial fluid surrounding the right ilium, with piriformis muscle calcification. [ncbi.nlm.nih.gov]

Abstract This study reports the clinical results of treatment for injection-induced pyogenic arthritis of the shoulder joint. [ncbi.nlm.nih.gov]

To discuss the indications and therapeutic outcomes of synovectomy, debridement, and continuous irrigation for the treatment of pyogenic arthritis caused by intra-articular injection used in the treatment of osteoarthritis of the knee. Methods. [journals.sagepub.com]

Patients with a positive culture from the hip or shoulder who had been pretreated with antibiotics had the worst prognosis. [ncbi.nlm.nih.gov]

Physicians should be aware that a delayed diagnosis results in a worse prognosis. [synapse.koreamed.org]

With adequate management the prognosis of suppurative sacroiliitis in pediatric patients is excellent, despite persistent abnormal radiographic findings in most patients. Received November 1, 1979. Accepted December 21, 1979. [pediatrics.aappublications.org]

[…] radiographs a fat-fluid level can be a specific sign in the absence of trauma MRI sensitive and more specific for early cartilaginous damage T1 : low signal within subchondral bone T2 : perisynovial edema C+ (Gd) : synovial enhancement Treatment and prognosis [radiopaedia.org]

Despite obtaining specimens from multiple sites for culture and using antigen detection tests only 64% of patients had an etiologic agent determined. [ncbi.nlm.nih.gov]

Joint aspiration under biplane fluoroscopic control and culture of the aspirated material is indicated in establishing the specific etiologic agent which is Staphylococcus aureus in most cases. [pediatrics.aappublications.org]

Etiology The gene responsible for the syndrome, the proline-serine-threonine phosphatase interacting protein 1 ( PSTPIP1 ) gene (previously known as the CD2 binding protein 1 ( CD2BP1 ) gene), was cloned in 2002. [orpha.net]

OBJECTIVE: To study the epidemiological characteristics and predictors of treatment outcomes for Thai patients hospitalized with PA. MATERIALS AND METHODS: The nationwide hospital database from the 2010 fiscal year was analyzed. [ncbi.nlm.nih.gov]

Patient Population: Prevalence and Epidemiology Knee // Shoulder & Elbow // Hip // Spine // Foot & Ankle // Hand & Wrist Fragility Fractures: Diagnosis and Treatment Shoulder & Elbow The Characteristics of Surgeons Performing Total Shoulder Arthroplasty [mdedge.com]

Objective To study the epidemiological characteristics and predictors of treatment outcomes for Thai patients hospitalized with PA. Materials and methods The nationwide hospital database from the 2010 fiscal year was analyzed. [onlinelibrary.wiley.com]

Summary Epidemiology To date, only 34 patients with PAPA syndrome have been reported worldwide, from five families (two in the USA, one in Italy, one in the Netherlands, and one in New Zealand). [orpha.net]

Gímenez, None. « Back to 2013 ACR/ARHP Annual Meeting ACR Meeting Abstracts - https://acrabstracts.org/abstract/pyogenic-arthritis-clinical-and-epidemiological-features-of-101-cases-at-a-university-hospital/ [acrabstracts.org]

The pathophysiology of septic arthritis – or how the disease occurs – is when organisms such as viruses, bacteria, or fungi enter the joint space directly (as in the case of an injury or injection that breaks the skin) or through the bloodstream from [joybauer.com]

Disseminated gonococcal infection: a prospective analysis of 49 patients and a review of pathophysiology and immune mechanisms. Medicine. 1983;62:395. PubMed CrossRef Google Scholar 14. Herndon WA, Knauer S, Sullivan JA, et al. [link.springer.com]

The purpose of this article is to provide an overview of the pathophysiology, diagnosis, treatment and long-term follow-up of septic arthritis in children. Figure 1. [racgp.org.au]

Surgery related Simultaneous bilateral arthroplasty Operative time >2.5 hours Allogenic blood transfusion Postoperative complications Delayed wound healing Atrial fibrillation Myocardial infarction Urinary tract infection (UTI) Prolonged hospital stay Pathophysiology [arupconsult.com]

[…] factors for neonatal septic arthritis prematurity (relatively immunocompromised) Cesarean section patients treated in the NICU invasive procedures such as umbilical catheterization, venous catheterization, heel puncture may lead to transient bacteremia Pathophysiology [orthobullets.com]

Preventive measures directed to patients with prosthetic joints or osteosynthetic material, and a known haematogenous source would have prevented at most 8% of all cases. bacterial arthritis prosthetic joint infection epidemiology prevention Statistics [doi.org]

Postoperative physiotherapy and mobilisation of the joint is necessary, while splinting prevents contractures. Early treatment may prevent severe complications such as dislocation, acvascular necrosis and late osteoarthritis. [www0.sun.ac.za]

Ice may also help prevent tissue damage. Use a cold compress, or put crushed ice in a bag. Cover it with a towel and apply it to your joint for 15 to 20 minutes every hour, or as directed. Exercise as directed. [drugs.com]

While there are no official guidelines on nutrition for septic arthritis, a nutrient-rich diet that can help prevent or fight infection may be beneficial. [joybauer.com]

Outpatient settings policy options for improving infection prevention. Atlanta, GA: US Department of Health and Human Services, CDC; 2015. [imic.or.jp]