Deficiency can occur in people with uremia, alcoholism, cirrhosis, hyperthyroidism, malabsorption syndromes, and congestive heart failure (CHF), and in those taking certain medications. Mild deficiency of vitamin B6 is common. [naturalmedicinejournal.com]

Author of: Benign childhood partial seizures and related epileptic syndromes London: John Libbey and Co. (1999)) Early-onset benign childhood occipital seizure susceptibility syndrome: a syndrome to recognise. Epilepsia 1999: 40:621-630 [books.google.com]

Seizure types include focal motor seizures, asymmetric tonic or clonic seizures, and epileptic spasms. [demosmedical.com]

[…] of pyridoxine, whatever the suspected cause pyridoxine dependent seizures pyridoxine responsive seizures epidemiology Statistics from Altmetric.com pyridoxine dependent seizures pyridoxine responsive seizures epidemiology Early onset seizures responsive [adc.bmj.com]

These seizures involve muscle rigidity, convulsions, and loss of consciousness (tonic-clonic seizures). [ghr.nlm.nih.gov]

Uncoupling of EEG-clinical neonatal seizures after antiepileptic drug use. Pediatr Neurol. 2003;28(4):277–280. 19. Mizrahi EM, Kellaway P. Characterization and classification of neonatal seizures. Neurology. 1987;37(12):1837–1844. 20. [demosmedical.com]

The classic clinical presentation is neonatal seizures responsive only to pyridoxine therapy. [pediatrics.aappublications.org]

ALDH7A1 mutations can also be identified in patients with neonatal seizures and other phenotypic presentations such as neonatal sepsis. [epilepsygenetics.net]

Key words : Pyridoxine dependent seizures; Neonatal seizures Pyridoxine-dependent epilepsy is a syndrome that usually presents with neonatal intractable seizures. It may present in later infancy or early childhood. [indianpediatrics.net]

Symptoms can include peripheral neuropathy, a pellagra-like syndrome, anemia, and seizures, which, particularly in infants, may not resolve when treated with anticonvulsants. [merckmanuals.com]

Detailed evaluation revealed that psychological symptoms were of alcohol-dependent syndrome and neurological symptoms were due to alcoholic peripheral neuropathy. [ijnpnd.com]

Other manifestations include anemia, peripheral neuropathy, and dermatitis. Treatment consists of pyridoxine 5 mg intramuscularly followed by 0.5 mg per day orally for 2 weeks. Correct dietary deficiency. [emedicine.medscape.com]

Subepidermal vesicular dermatosis and sensory peripheral neuropathy caused by pyridoxine abuse. J Am Acad Dermatol 1986; 14: 915-7. Parry G, Bredesen D. Sensory neuropathy with low dose pyridoxine. Neurology 1985; 35: 1466-8. [drugs.com]

A wide range of focal seizures (anything from tonic posturing to autonomic signs) is very common and tonic spasms are also seen. [demosmedical.com]

In their study, severe acute pyridoxine deficiency in young ducklings was also characterized by severe anemia while chronic pyridoxine deficiency in older ducklings produced paralysis, convulsions, severe microcytic anemia, and poor feather development [medical-dictionary.thefreedictionary.com]

While this may be correct in some cases, P5P deficiency can also cause microcytic anemia. [metabolichealing.com]

Vitamin B 6 deficiency may impair hemoglobin synthesis and lead to microcytic anemia (3). Deficiency in another B vitamin, niacin, is easily prevented by adequate dietary intakes. [lpi.oregonstate.edu]