Rabies, one of the oldest infectious diseases, still presents a public health threat in most parts of the world today. [ncbi.nlm.nih.gov]

• Intravenous Administration

  Following intravenous administration, the pseudovirus effectively infected the mice, with dynamic viral distributions being sequentially observed in spleen, liver and brain. [ncbi.nlm.nih.gov]

• Neglect

  To our surprise, the impact of these changes on the functionality is completely neglected. [ncbi.nlm.nih.gov]

• Cytoplasmic Inclusion Bodies

  Histopathology indicated that eosinophilic and cytoplasmic inclusion bodies, Negri bodies, were seen in neuronal cells of the CNS. Inflammatory cell reactions were scarce, and no apoptosis in the CNS was detected. [ncbi.nlm.nih.gov]

These findings suggest that the rhuIFN α-2a might have some anti-viral activity, which can be used for the treatment of rabies infection. [ncbi.nlm.nih.gov]

Our novel treatment, dubbed the Milwaukee protocol, has stirred controversy among medical specialists; some claim that Jeanna's cure was a fluke. [scientificamerican.com]

Moreover, although the disease is rarer than other human infections such as influenza, the prognosis following a bite from a rabid animal is poor: There is currently no effective treatment that will save the life of a symptomatic rabies patient. [ncbi.nlm.nih.gov]

However its epidemiology remains largely unappreciated in much of these regions, such as in Nepal, where limited information is available about the spatiotemporal dynamics of the main etiological agent, the rabies virus (RABV). [ncbi.nlm.nih.gov]

Adelchi Negri reported the identification of what he believed to be the etiologic agent of rabies, the Negri body. [whonamedit.com]

The etiology of rabies and the work of Adelchi Negri (1876–1912). In: Camillo Golgi (1843–1926), Santiago Ramón y Cajal (1852–1934), Adelchi Negri (1876–1912). [dx.doi.org]

Author information 1 Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, 130062, China. 2 Section of Epidemiology and Public Health, College of Veterinary and [ncbi.nlm.nih.gov]

Disease Control and Prevention, Beijing, 102206, China. [ncbi.nlm.nih.gov]