Disorders, UCL Institute of Neurology, University College London, Queen Square, London WC1N 3BG, United Kingdom. 4 From Gene Therapy, Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College [ncbi.nlm.nih.gov]

Following intravenous administration, the pseudovirus effectively infected the mice, with dynamic viral distributions being sequentially observed in spleen, liver and brain. [ncbi.nlm.nih.gov]

Encephalitis developed in all four recipients within 30 days after transplantation and was accompanied by rapid neurologic deterioration characterized by agitated delirium, seizures, respiratory failure, and coma. [ncbi.nlm.nih.gov]

Histopathology indicated that eosinophilic and cytoplasmic inclusion bodies, Negri bodies, were seen in neuronal cells of the CNS. Inflammatory cell reactions were scarce, and no apoptosis in the CNS was detected. [ncbi.nlm.nih.gov]